Clinical trials: Early Childhood Caries
Early Childhood Caries
Clinical Efficiency and Child's Behavior of Hall Versus SDF Techniques in the Management of Carious Primary Molar:
This study will compare two non- invasive treatment options: Hall technique and 38% Silver diamine fluoride. Both are methods used to create a more favorable environment without removal of caries leading to the arrest of the…
- Trial name
- NCT04737057
- Testing
- SDF, Hall technique
- Volunteers
- 72 people
- Sponsor
- Cairo University
Early Childhood Caries
Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC)
Considering the severity and high prevalence of ECC, as well as the importance of early intervention and approach, the Atraumatic Restorative Treatment program, because of its advantages, consists of an important treatment…
- Trial name
- ART-ECC (NCT03756025)
- Testing
- Atraumatic Restorative Treatment (ART)
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Dental Caries, Dental Caries in Children
Atraumatic Versus Silver-Modified Atraumatic Restorative Treatment in Primary Molars
The goal of this clinical trial is to evaluate and compare the short-term effectiveness of two minimally invasive treatments-Atraumatic Restorative Treatment (ART) and Silver-Modified Atraumatic Restorative Treatment (SMART)-in…
- Trial name
- NCT07023939
- Testing
- ART: Atraumatic restorative treatment, SMART: Silver-Modified Atraumatic Restorative Treatment
- Where
- Lebanon
- Volunteers
- 34 people
- Sponsor
- Beirut Arab University
Early Childhood Caries, Dental Caries in Children
Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and the Effects on Oral Health Related Quality of Life
There is still a need for the assessment of different minimal intervention strategies and treatments focusing on the prevention and arrest of carious lesions of primary molars The evidence-based clinical practice guideline on…
- Conditions
- Early Childhood Caries, Dental Caries in Children, Dental Caries Extending Into Dentin, Dental Caries
- Trial name
- NCT05772039
- Testing
- Topical application of 38% Silver Diammine Fluoride Solution, Topical application of 5% Sodium Fluoride with functional Tricalcium phosphate Varnish
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Universiti Sains Malaysia
Child, Early Childhood Caries
Evaluation of Remineralizing Efficacy of Combination Varnishes on White Spot Lesions in ECC Children
The remineralizing efficacy of 3 fluoride varnishes were assessed in children with white spot lesion under 6 years of age ( children with early childhood caries)
- Trial name
- NCT03360266
- Testing
- Sodium Fluoride with CPP-ACP varnish, sodium fluoride with ACP varnish, 5% Sodium Fluoride Varnish
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indira Gandhi Institute of Dental Science
Dental Caries in Children
Social Impact of Children's Dental Appearance
This study evaluates the social impact of children's dental perception from children with or without caries experience. For this, children and their parents are shown pictures of child faces with healthy teeth, decayed teeth and…
- Trial name
- NCT03800043
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Göttingen
Dental Caries, Early Childhood Caries
Preventing Early Childhood Caries in Indigenous Children: the Baby Teeth Talk Study
The purpose of this study is to determine whether a combination of pre- and post-natal preventive and behavioral interventions is effective in preventing early childhood caries in Indigenous children.
- Trial name
- BTT (NCT02151916)
- Testing
- Dental care, AG, MI & fluoride varnish, Delayed intervention
- Where
- Canada
- Volunteers
- 544 people
- Sponsor
- University of Toronto
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Early Childhood Caries
Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre
To determine the optimal application time of silver diamine fluoride (38% SDF) in arresting dental caries in the primary teeth of preschool children.
- Trial name
- NCT04655430
- Testing
- 3-second SDF application, 5-second SDF application, 10-second SDF application
- Where
- Hong Kong
- Volunteers
- 665 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Candida Infection, Oral Thrush
Oropharyngeal Candidiasis (OPC) and S-ECC
The overall objective of this study is to investigate the association of early Candida infection (known as oral thrush or oropharyngeal candidiasis, OPC) in children during the first year of life with the onset and severity of…
- Conditions
- Candida Infection, Oral Thrush, Early Childhood Caries
- Trial name
- Oral-Thrush (NCT05761197)
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Temple University
Pediatric Dental General Anesthesia, Restoration
Clinical Performance and Failure Rates of Restorations Following Pediatric Dental Rehabilitation Under General Anesthesia
Full-mouth dental rehabilitation under general anesthesia (GA) is frequently required for young children with extensive dental caries, behavioral challenges, or special healthcare needs.
- Conditions
- Pediatric Dental General Anesthesia, Restoration, Clinical Performance, Full Mouth Rehabilitation
- Trial name
- NCT07827833
- Testing
- Routine Restorative Materials and Treatment Methods
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Tanta University
Early Childhood Caries (ECC)
Caries Risk in Children Treated Under General Anesthesia for Early Childhood Caries
This observational, cross-sectional study aims to evaluate the current caries risk profiles of children who underwent dental treatment under general anesthesia (GA) for early childhood caries (ECC) between 2015 and 2020 at Aydın…
- Trial name
- NCT07330570
- Testing
- Caries Risk Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Dental Caries, Early Childhood Caries
Cohort Zero Caries
The purpose of this study is to compare the effectiveness of a traditional oral health educational program and a program based on the theories of the Motivational Interview directed to the child's mothers/fathers/responsible…
- Trial name
- CZC (NCT02578966)
- Testing
- Motivational Interview, Traditional health education
- Volunteers
- 650 people
- Sponsor
- Hospital Nossa Senhora da Conceicao
Early Childhood Caries
Silver Diamine Fluoride Effectiveness Versus Atraumatic Restorative Treatment in Arresting ECC
The study was conducted to evaluate the effectiveness of the biannual application of 38% silver diamine fluoride in arresting early childhood caries when compared to atraumatic restorative treatment.
- Trial name
- NCT04514094
- Testing
- SDF, ART
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Hams Hamed Abdelrahman
Dental Caries in Children, Diet Habit
Maternal Control of the Child's Feeding, Child's Eating Behavior and Early Childhood Caries in Preschoolers
Dental caries in children is considered one of the most prevalent oral diseases of this age group, leading to significant manifestations presenting as pain, interference with feeding, higher risk of developing dental caries in…
- Conditions
- Dental Caries in Children, Diet Habit, Dietary Exposure, Eating Behavior
- Trial name
- NCT06898918
- Where
- Egypt
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Oral Health Related Quality of Life OHRQoL
Does Treating Early Childhood Caries Under Local or General Anesthesia Have Varying Effects on OHRQoL
A two-arm randomized control trial is to compare the changes in OHRQoL scores among children treated for ECC under general (DGA) and local anesthesia (LA).
- Trial name
- NCT05761691
- Testing
- Dental treatment
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Early Childhood Caries, Oral Hygiene
Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries
Few educational oral health applications, directed to the preschool children under the age of six years are available world-wide.
- Conditions
- Early Childhood Caries, Oral Hygiene, Oral Health
- Trial name
- FU-APP (NCT05515510)
- Testing
- FU-APP, Oral health recommendations
- Where
- Germany
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Early Childhood Caries (ECC), Color Stability of Restoration
Evaluation of Silver Diamine Fluoride, Sodium Fluoride With Casein Phosphopeptide-Amorphous Calcium Phosphate(MI Varnish) and Dycal to Arrest Caries When Used in Indirect Pulp Capping Procedures in Children
Early childhood caries is a serious public health issue often neglected and goes untreated having detrimental effects on the child and their family. Hence, multiple teeth are affected with dental caries approaching close to pulp.
- Conditions
- Early Childhood Caries (ECC), Color Stability of Restoration, Caries Arrested, Caries,Dental
- Trial name
- SDF (NCT07893756)
- Testing
- Silver Diamine Fluoride (SDF, 38%) gel, Sodium Fluoride with CPP-ACP (MI varnish), Calcium Hydroxide (CH)
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- University of Jazan
Dietary Supplement
Probiotics in Children With Early Childhood Caries
The purpose of this study is to determine if probiotic lozenges taken once a day before bedtime for twelve weeks can decrease the numbers of Streptococcus mutans
- Trial name
- NCT03998306
- Testing
- Experimental: Probiotics, No intervention
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester