Clinical trials: Diabetic Peripheral Neuropathy
Diabetes Mellitus, Diabetes Complications
New Diagnostic Tool (MinION) for Identifying Microorganisms in Foot Wounds of Patients Living With Diabetic Foot Osteomyelitis
Diabetic foot wound infections are predominantly polymicrobial. However, 'conventional' microbiological culture does not identify all the bacteria potentially involved in these infections and requires time, which can have a…
- Conditions
- Diabetes Mellitus, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- MINI-OS (NCT07391995)
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Diabetic Neuropathy Peripheral
Evaluating a Nitric Oxide Generator, Nebivolol as a Disease Modifier in Patients With Diabetic Neuropathy.
The goal of this clinical trial is to test in patients with diabetic neuropathy, Can Nevibolol at a dose of 2.5 mg- 10 mg compared with standard pain modulating treatment conserve the mean nerve action potential amplitude (sural…
- Trial name
- EVANESCENT-DPN (NCT06201611)
- Testing
- Nebivolol+ Standard care arm, Epalrestat + Alpha Lipoic Acid +Standard care, Standard care alone
- Where
- 2 sites in India
- Volunteers
- 120 people
- Sponsor
- St. John's Research Institute
Diabetes Type 1, Proteomics
Proteomic Analysis in Paediatric Diabetes Type 1 (PAPD)
The aim of the present study is to investigate a targeted proteomic analysis in plasma of children - of Greek origin- with type 1 diabetes (DT1) and its correlation with the electrophysiological findings that accompany diabetic…
- Conditions
- Diabetes Type 1, Proteomics, Diabetic Peripheral Neuropathy
- Trial name
- PAPD (NCT04257877)
- Testing
- Blood sampling
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Diabetic Peripheral Neuropathy
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy.
- Trial name
- NCT06041399
- Testing
- hypoglycemic Agents(metformin), lipid-lowering drug(Statin)
- Where
- China
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Diabetic Peripheral Neuropathy
The Effect of Related Blood Markers on Diabetic Peripheral Neuropathy
The goal of this observational study is to explore the relationship between related blood indicators and diabetic peripheral neuropathy(DPN).
- Trial name
- NCT06041412
- Where
- China
- Volunteers
- 1,400 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Organic, Including Symptomatic, Mental Disorders, Substance Use
Exploring the Comorbidity Between Mental Disorders and General Medical Conditions
Mental disorders have been shown to be associated with a number of general medical conditions (also referred to as somatic or physical conditions).
- Conditions
- Organic, Including Symptomatic, Mental Disorders, Substance Use, Schizophrenia, Mood [Affective] Disorders
- Trial name
- COMO-GMC (NCT03847753)
- Testing
- Organic Disorders, Substance Use Disorders, Schizophrenia Disorders
- Volunteers
- 5,940,299 people
- Sponsor
- University of Aarhus
Diabetic Peripheral Neuropathy
Effect of Rotating Magnetic Therapy on Diabetic Peripheral Neuropathy
The aim of the study is to assess the effect of Rotating Magnetic Therapy on Diabetic Peripheral Neuropathy using Nerve conduction velocity examination.
- Trial name
- NCT03983200
- Testing
- Rotating Magnetic Therapy, Mecobalamin
- Volunteers
- 200 people
- Sponsor
- Majianhua
Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy
Prevalence of Peripheral Neuropathy in Children and Adolescents With Type I Diabetes Mellitus: a Prospective Study
Diabetes mellitus type I is an increasing burden for more and younger children. Therapy should avoid long-term complications as macrovascular diseases and diabetic nephropathy, retinopathy and diabetic neuropathy (DN).
- Conditions
- Diabetes Mellitus Type I, Diabetic Peripheral Neuropathy, Nerve Conduction Study Not Performed
- Trial name
- NCT01512030
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Landeskrankenhaus Feldkirch
Diabetic Neuropathies, Peripheral Nerve Diseases
Effect of Exercise on Gait and Balance in Peripheral Neuropathy
The purpose of this study is to find out if participation in one of the study groups: functional balance training, Tai Chi, or education, results in better outcomes overall.
- Conditions
- Diabetic Neuropathies, Peripheral Nerve Diseases, Peripheral Nervous System Diseases
- Trial name
- NCT00270842
- Testing
- Tai Chi, Functional Balance, Education Control group
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- US Department of Veterans Affairs
Diabetic Peripheral Neuropathy
Restoration of Cutaneous Sensorum in Patients With Diabetic Peripheral Neuropathy (DPN) Via Metanx®
The purpose of this research study is to determine if Metanx improves sensory neuropathy in persons with Type 2 diabetes. Metanx is a medical food available with a prescription from a physician.
- Trial name
- NCT00933998
- Testing
- Metanx® (Oral L-methylfolate, Methylcobalamin and Pyridoxal 5'-phosphate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Carolina Musculoskeletal Institute
Neuropathy; Peripheral, Autonomic, in Diabetes Mellitus (Manifestation)
The Relationship Between Vascular Adhesion Protein-1 and Diabetic Cardiovascular Autonomic Neuropathy
Exploring the relationship between serum VAP-1 and cardiovascular autonomic neuropathy in subjects with type 2 diabetes mellitus
- Trial name
- NCT01706289
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabetes Mellitus, Peripheral Neuropathy
Botulinum Toxin Effects on Plantar Ulcer Recurrence
The purpose of this grant is to collect pilot data to assess the amount of botulinum toxin that needs to be injected into the calf muscles of subjects with diabetes mellitus, peripheral neuropathy, and a plantar ulcer to decrease…
- Conditions
- Diabetes Mellitus, Peripheral Neuropathy, Plantar Ulcers
- Trial name
- NCT00845897
- Testing
- Botulinum Toxin, Saline
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Foot Ulcer
Achilles Tendon Lengthening in Patients With Diabetes to Prevent Foot Ulcers
People with diabetes often develop severe skin problems (ulcers) on their feet. Sometimes these are treated with surgery and other times by temporarily immobilizing the foot in a cast.
- Conditions
- Diabetes Mellitus, Foot Ulcer, Peripheral Neuropathy
- Trial name
- NCT00006426
- Testing
- Achilles tendon-lengthening surgery
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)