Clinical trials: Developmental Disabilities
Autism Spectrum Disorder
Cognoa Autism Spectrum Disorder (ASD) Digital Therapeutic Engagement and Usability Study
Cognoa will measure usability, engagement with the device, and changes in parent-reported socialization during a 4-week period of intervention at home with the Cognoa ASD therapeutic device.
- Trial name
- NCT04326231
- Testing
- Usability assessment of Cognoa ASD Therapeutic Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cognoa, Inc.
Autism Spectrum Disorder
PEACE for ImPACT Study
Investigators will test the impact of the PEACE implementation toolkit and determine the level of implementation support needed to improve early intervention providers use of caregiver coaching with families of young children…
- Trial name
- NCT06374381
- Testing
- PEACE Online Resources, PEACE Weekly Group Facilitation, PEACE Weekly Individual Facilitation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Autism, Emotion Regulation Difficulties
Enhancing Emotion Regulation in Children With Autism Through Extended Reality
Pilot study on the development of an Extended Reality (XR) application to support emotion regulation in children with Autism Spectrum Disorder (ASD) (random assignment to an experimental group, N = 10, and a control group, N =…
- Trial name
- ERAC-XR (NCT07838272)
- Testing
- Extended Reality, Emotion regulation coaching
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Johannes Kepler University of Linz
Autism Spectrum Disorder, Autism
Oral Health Care in Autism Spectrum Disorder
Persons with autism spectrum disorder (ASD) are characterized by impairments in social interactions, speech and communication, restricted patterns of behaviour, and unusual sensory sensitivities.
- Trial name
- CREASED (NCT03830541)
- Testing
- Oral care delivery analysis in participants with ASD
- Volunteers
- 52 people
- Sponsor
- University of Novi Sad
Autism Spectrum Disorder
Care Pathway for Children With Autism Spectrum Disorder Included in the ELENA Cohort
Autism Spectrum Disorder (ASD) is lifelong neurodevelopmental disorder that affect social communication and interaction and includes limited and repetitive patterns of behavior (DSM 5).
- Trial name
- ELENA-SNDS (NCT04292522)
- Where
- France
- Volunteers
- 903 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder
Sensory and Behavioral Aspects With Particular Attention to Food Selectivity in Children With Autism
Brief Summary: Eating problems and in particular food selectivity is a condition that worsens a long-life disorder such as Autism Spectrum Disorder (ASD) , both on an individual level, both on family and social ones .
- Trial name
- NCT06335030
- Where
- 3 sites in Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Fondazione Stella Maris
Autism Spectrum Disorder, Anxiety
A Pilot Study of Buspirone for the Treatment of Anxiety in Youth with Autism Spectrum Disorders
The main objective of this exploratory 8-week pilot study is to evaluate the safety and efficacy of buspirone for the treatment of anxiety in youth (ages 6-17 years) with autism spectrum disorders.
- Trial name
- NCT03432065
- Testing
- Buspirone
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder (ASD)
Non-Helium Magnetoencephalography in Autism Spectrum Disorder
The goal of this observational study is to learn how brain activity in children with autism spectrum disorder (ASD) differs from typical developing children using magnetoencephalography (MEG).
- Trial name
- NCT07064967
- Testing
- Magnetoencephalography
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Autistic Disorder
Study of Acamprosate in Autism
Recent pharmacotherapy research in autism spectrum disorders (ASD) has successfully focused on treatment of co-occurring symptoms, including inattention, hyperactivity, and irritability that commonly occur in persons with ASD.
- Trial name
- NCT01813318
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autistic Disorder
Evaluation of the Efficiency of Treatment by BUMETANIDE on Autistic Children With a Known Ethiology
During a previous therapeutic trial, investigators showed that the bumetanide improved significantly autism. This trial showed that a therapeutic response was obtained in 75% of cases.
- Trial name
- BUMAUTEP (NCT02947880)
- Testing
- Bumetanide
- Where
- France
- Sponsor
- University Hospital, Limoges
Autism Spectrum Disorder, Gastrointestinal Diseases
Fecal Microbiota Transplantation for Patients With Autism Spectrum Disorder.
This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the…
- Conditions
- Autism Spectrum Disorder, Gastrointestinal Diseases, Healthy
- Trial name
- NCT06290258
- Testing
- Fecal microbiota transplantation
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Child Development, Physical Disability
Children Participation Assessment Scale
Increasing the number of Turkish versions of questionnaires evaluating participation will increase the variety of assessment methods.
- Conditions
- Child Development, Physical Disability, Participation, Patient
- Trial name
- NCT05107518
- Testing
- Children Participation Assessment Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gazi University
Autism Spectrum Disorder
Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial
The goal of this study is to target the neurobiology of restricted and repetitive behaviors in children with autism spectrum disorder using N-acetylcysteine (NAC), a well-tolerated nutritional supplement that has shown promise…
- Trial name
- NCT05664789
- Testing
- N acetyl cysteine
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Stanford University
Autism Spectrum Disorder, Autistic Disorder
Sensorimotor Affect Relationship-based Therapy (SMART) for Children With Autism Spectrum Disorders Ages 2-12
The SMART Program at Nationwide Children's Hospital is an interdisciplinary social skills group that teaches children with autism spectrum disorders (ASD) ages 2-12 the fundamental social skills necessary to build and maintain…
- Trial name
- SMART (NCT01977248)
- Testing
- Sensorimotor Affect Relationship-based Therapy (SMART)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Nationwide Children's Hospital
Autism
Ziprasidone in Children With Autism: A Pilot Study
The purpose of this study is to see if the drug, ziprasidone, is effective in treating problems in adolescent associated with autism.
- Trial name
- NCT00208559
- Testing
- Ziprasidone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Drexel University College of Medicine
Autism Spectrum Disorder, Conduct Disorder
Effectiveness of a Short Computer-based Emotion Recognition Training in Different Patient Groups
Emotion recognition and regulation are necessary skills for social interaction. Disrupted development of these processes severely interferes with socio-emotional development.
- Trial name
- NCT04845243
- Testing
- Emotionen Verstehen und Ausdrücken (E.V.A.)
- Volunteers
- 80 people
- Sponsor
- Prof. Christina Stadler
Autism Spectrum Disorder, Early Developmental Impairment
Multicenter Validation Study on Autism Screening Using a Machine-assisted System
The goal of this observational study is to assess the effectiveness of a machine-assisted system for early screening of autism. The main questions it aims to answer are: Does the machine-assisted system including 5 main…
- Conditions
- Autism Spectrum Disorder, Early Developmental Impairment, Language Development Disorders
- Trial name
- NCT07006948
- Testing
- Autism Diagnostic Observation Schedule, the 2nd edition(ADOS-2), Griffiths Developmental Scales, Chinese edition(GDS-C)
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Autism Spectrum Disorder
Effect of Combined Music and Taekwondo Training for Children with Autism Spectrum Disorder
The goal of this randomized controlled trial is to evaluate the effect of combined music and taekwondo training on the mental and physical condition of children with autism spectrum disorder.
- Trial name
- NCT06277778
- Testing
- Taekwondo training with music therapy, Taekwondo training alone
- Where
- Hong Kong
- Volunteers
- 70 people
- Sponsor
- The Hong Kong Polytechnic University
Autism Spectrum Disorder
Early Intervention, Supervision, Quality and Outcome in ASD
The objective of this study is to examine the significance of knowledge of autism spectrum disorder (ASD), and early intensive behavioral intervention, as well as trust in EIBI, adequate assessment of EIBI quality, and EIBI…
- Trial name
- NCT03196713
- Testing
- Early Intensive Behavioral Intervention
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Karolinska Institutet
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