Clinical trials: Depression and/or Anxiety Symptoms
Depression and/or Anxiety Symptoms, Problematic Phone Use Behavior
The Mindful Smartphone Use Study
The goal of this clinical trial is to understand the feasibility and acceptability on a mindfulness-based intervention to address co-existing smartphone addiction and psychological distress among adolescents ages 13-19…
- Trial name
- NCT07892807
- Testing
- Mindwire
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brown University
Depressive Symptoms, Anxiety Disorders and Symptoms
Family Spirit Strengths
This project addresses the disproportionate morbidity and mortality associated with mental and behavioral health problems in American Indian and Alaska Native communities.
- Conditions
- Depressive Symptoms, Anxiety Disorders and Symptoms, Substance Use, Mental Health Issue
- Trial name
- FSS (NCT05836090)
- Testing
- Family Spirit Strengths (FSS), Family Spirit Nurture
- Where
- 3 sites in United States
- Volunteers
- 188 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Anxiety Symptoms, Post-traumatic Stress Symptoms
Improving Student Mental Health Through a Universal Trauma-Informed Intervention
The goal of this trial is to identify the most effective ways for schools to deliver RAP Club, a universal school-based mental health intervention.
- Conditions
- Anxiety Symptoms, Post-traumatic Stress Symptoms, Depressive Symptoms, Behavioral Problems
- Trial name
- PPP (NCT07842432)
- Testing
- RAP Club Delivered by a School Clinician, RAP Club Delivered by a Teacher, Standard Supervision
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Post-Traumatic Stress Disorder, Depressive Symptoms
Efficacy of EMDR Versus CBT for Post-Traumatic Stress and Comorbid Disorders in Pakistan: A Randomized Controlled Feasibility-Pilot Study
Post-Traumatic Stress Disorder (PTSD) is commonly accompanied by symptoms of depression and anxiety. Eye Movement Desensitization and Reprocessing (EMDR) and Cognitive Behavioral Therapy (CBT) are evidence-based psychological…
- Conditions
- Post-Traumatic Stress Disorder, Depressive Symptoms, Anxiety Symptoms
- Trial name
- NCT04021329
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Trauma-Focused Cognitive Behavioral Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Khushal Khan Khattak Univeristy, Karak, Pakistan
PTSD Symptoms, Anxiety Symptoms
Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida
This study examines mental health challenges among World Trade Center (WTC) General Responders, who continue to experience significant psychological trauma from the WTC collapse.
- Conditions
- PTSD Symptoms, Anxiety Symptoms, Depression Symptoms, Sleep Disturbance
- Trial name
- PTSDCoach911 (NCT06648928)
- Testing
- Clinician Supported PTSD Coach, Self Managed PTSD Coach
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida International University
Depression - Major Depressive Disorder, Anxiety
No Time to Wait: Single Session Intervention
Mental health problems in youth are prevalent, but early intervention effectively reduces symptoms, substance abuse risk, suicide, and comorbidities.
- Trial name
- NCT07383467
- Testing
- Online Single Session Intervention on Growth Mindset
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- United Christian Hospital
Autism Spectrum Disorder, Somatic Symptom Disorder
Somatic Symptoms in Autism Spectrum Disorder: Data Integration
Autistic patients have higher rates of co-morbid somatic symptoms. Thus, compared to the general population, they experience more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular…
- Trial name
- NCT05886361
- Testing
- No intervention involved
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Emotion Regulation, Depressive Symptoms
Music Program for Hong Kong Adolescents: Improving Emotion Regulation and Reducing Depression, Anxiety, and Loneliness
This study is a clinical trial that aims to test and validate a music-based program called "Tuned In" in helping adolescents in Hong Kong improve their mental well-being.
- Conditions
- Emotion Regulation, Depressive Symptoms, Anxiety, Loneliness
- Trial name
- NCT06147297
- Testing
- Tuned In
- Where
- Hong Kong
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Artificial Intelligence (AI), Prolonged Grief Symptoms
AI-GF-GNW on Prolonged Grief Reactions
Prolonged Grief Disorder (PGD) is a severe, disabling condition characterized by intense yearning and difficulty accepting the reality of loss, which significantly impairs the academic and psychosocial functioning of bereaved…
- Conditions
- Artificial Intelligence (AI), Prolonged Grief Symptoms, Depression - Major Depressive Disorder, Anxiety
- Trial name
- NCT07589088
- Testing
- AI-Assisted Grief-Focused Guided Narrative Writing, No-Feedback Guided Narrative Writing, Free Writing
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Peking University
Trauma-related Mental Health Symptoms
Adaptation and Examination of a Trauma-informed Intervention for Pregnant Veterans
The current proposal aims to refine and examine an intervention called Calm Moms. Calm Moms is a web-based treatment program designed to reduce anxiety, stress, and low mood symptoms among pregnant Veterans with a history of…
- Trial name
- NCT06906185
- Testing
- Calm Moms-V, Care As Usual
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Depressive Symptoms, Conduct Disorder
Intervening Early: Key Adolescent Outcomes
This study follows children into adolescence who were first randomized to intervention condition in infancy.
- Conditions
- Depressive Symptoms, Conduct Disorder, Anxiety Disorders
- Trial name
- SCOH-A (NCT04168684)
- Testing
- Attachment and Biobehavioral Catch-up (ABC), Developmental Education for Families (DEF)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Delaware
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Anxiety Disorders and Symptoms, Depressive Symptoms
Transdiagnostic, Indicated Preventive Intervention for Adolescents At High Risk of Emotional Problems W/Add-On Modules
PROCARE is a preventive intervention that has shown its effectiveness in selective prevention to reduce young people's risk of developing emotional problems.
- Trial name
- PROCARE-I+ (NCT06350760)
- Testing
- Active control condition, PROCARE-I+ 8-session
- Where
- 3 sites in Spain
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Depressive Symptoms, Anxiety
School-based Group Acceptance and Commitment Therapy for Adolescents
The objective of the investigators' mental health promotion intervention premised on the Acceptance and Commitment Therapy (ACT) framework in secondary school settings aims to enhance young people's psychological flexibility and…
- Conditions
- Depressive Symptoms, Anxiety, Stress
- Trial name
- NCT06039228
- Testing
- Acceptance and commitment therapy
- Where
- Hong Kong
- Volunteers
- 61 people
- Sponsor
- Chinese University of Hong Kong
Childhood Cancer, Depressive Symptoms
Cultivating Resilience in Oncology Practice
The purpose of the CROP study is to investigate the potential to cultivate psychological resources and resilience in childhood cancer patients and their family members using a mobile phone-based intervention.
- Conditions
- Childhood Cancer, Depressive Symptoms, Anxiety Disorders and Symptoms, Mental Health Issue
- Trial name
- CROP (NCT04902313)
- Testing
- Awareness and insight Modules (AiM)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Resilience, Depressive Symptom
Musical Training to Enhance Resilience of Underprivileged School-aged Children
This is a multi-centre randomised controlled trial aims to examine the effects of a group-based gamified instrumental musical training in enhancing resilience (primary outcome), reducing psychological distress (depressive…
- Conditions
- Resilience, Depressive Symptom, Anxiety
- Trial name
- NCT07165925
- Testing
- Gamified music training
- Where
- Hong Kong
- Volunteers
- 174 people
- Sponsor
- Chinese University of Hong Kong
Depressive Symptoms, Anxiety
Culturally Adapted iCBT for Arabic-speaking Refugee and Migrant Youth With Common Mental Health Problems
The aim of the current study is to explore whether culturally adapted internet-based cognitive behavioral therapy is effective in reducing the symptoms of various common mental health problems among Arabic-speaking refugee and…
- Conditions
- Depressive Symptoms, Anxiety, Insomnia, Grief
- Trial name
- RAHA (NCT06102096)
- Testing
- Culturally Adapted iCBT
- Where
- Sweden
- Volunteers
- 125 people
- Sponsor
- Karolinska Institutet
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu