Clinical trials: Curcumin
Bleeding, Implants
Use of Curcumin to Treat Unfavorable Bleeding Patterns in Contraceptive Implant Users
The investigators plan to study the effects of curcumin, the active ingredient in the spice turmeric, on the irregular bleeding experienced by women who use the contraceptive implant.
- Conditions
- Bleeding, Implants, Breakthrough Bleeding
- Trial name
- NCT04205929
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Traumatic Pulp Exposure in Children
Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth
The aim of the study is to evaluate clinical and radiographic effect of nano propolis and nano curcumin as direct pulp capping agents in young permanent teeth. .
- Trial name
- NCT06029023
- Testing
- MTA Cement, propolis nano particle, curcumin nanoparticles
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Childhood Obesity
Efficacy Evaluation of a Mixed Compound of Antioxidants in Terms of Endothelium Damage/Function in Pediatric Subjects With Obesity.
The aim of our study was to test the effects on endothelium of a combination of curcumin, resveratrol, plus zinc, magnesium, selenium and Vitamin D in a cohort of pediatric subjects with obesity.
- Trial name
- OBELIX (NCT04723849)
- Testing
- Auxilie® Immuplus, Envicon Medical, Verona, Italy
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- Universita di Verona
NAFLD - Nonalcoholic Fatty Liver Disease, NASH - Nonalcoholic Steatohepatitis
Curcumin for Pediatric Nonalcoholic Fatty Liver Disease
This is a single-center, randomized, double-blinded, placebo-controlled, parallel treatment groups phase 2a study of curcumin for pediatric nonalcoholic fatty liver disease (NAFLD).
- Trial name
- NCT04109742
- Testing
- phosphatidylcholine-curcumin complex supplement
- Sponsor
- Columbia University
Recurrent Aphthous Ulcer, Recurrent Aphthous Stomatitis
Curcumin and Nanocurcumin in Oral Aphthous Ulcer
Recurrent aphthous ulcer is a painful inflammatory lesion with a high prevalence. Since the etiology is not clear, several strategies have been proposed to reduce pain and severity of its symptoms.
- Trial name
- NCT04385979
- Testing
- Gel
- Where
- Iran
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Inflammatory Bowel Disease, Ulcerative Colitis
Curcumin in Pediatric Inflammatory Bowel Disease
This is a single center, open label forced dose titration study designed to determine the tolerability of curcumin in pediatric patients with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn's Disease
- Trial name
- NCT00889161
- Testing
- Curcumin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Seattle Children's Hospital
Multiple Myeloma
Curcumin (Diferuloylmethane Derivative) With or Without Bioperine in Patients With Multiple Myeloma
Primary Objectives: 1. To evaluate clinical tolerance and response to curcumin alone and in combination with Bioperine in patients with multiple myeloma. 2.
- Trial name
- NCT00113841
- Testing
- Curcumin, Bioperine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- M.D. Anderson Cancer Center
Healthy Children
An Investigator-initiated Trial to Assess the Effectiveness of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children
An Open-Label, Three-Arm, Parallel, Investigator-Initiated Trial of Three Different Gummies (Curcumin Gummies, Vitamin C Gummies, and Vitamin B Complex Gummies) in Healthy Children.
- Trial name
- NCT05775237
- Testing
- Curcumin Gummies, Vitamin C Gummies, Multivitamin Gummies
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Periodontitis
Efficacy of Nano-Curcumin and Nano-Hyaluronic Acid as an Adjunct to Scaling and Root Planing in the Treatment of Periodontitis
to evaluate Efficacy of Locally Applied Nano-Curcumin and Nano-Hyaluronic Acid as an Adjunct to Scaling and Root Planing in the Treatment of Periodontitis patients Materials and methods: forty patients (n=40) were selected from…
- Trial name
- NCT06777303
- Testing
- curcurmin loaded on chitosan nano-particles, hyaluronic acid loaded on chitosan nano-particles, scaling and root planning
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Ulcerative Colitis
Curcumin in Pediatric Ulcerative Colitis
Background: Curcumin in an active phytochemical substance, used as part of the human diet, that has anti-inflammatory and anti-oxidative properties which were demonstrated in multiple experimental models of colitis including a…
- Trial name
- NCT02277223
- Testing
- Curcumin
- Where
- Israel
- Sponsor
- Schneider Children's Medical Center, Israel
Oral Mucositis, Pediatric Cancer
Curcumin VS Photo-bio-modulation Therapy of Oral Mucositis in Pediatric Patients Undergoing Anti-Cancer Non-invasive Treatment
The main objective of this study is to assess the impact of non-invasive photodynamic therapy by Curcumin and photo-bio-modulation low level (LL) laser treatment in managing mucositis induced by chemotherapy in pediatric…
- Trial name
- NCT06044142
- Testing
- Curcumin, Laser
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Riyadh Elm University
Cutaneous T-cell Lymphoma
Trial of Curcumin in Cutaneous T-cell Lymphoma Patients
The goal of this clinical research study is to learn if treatment with curcumin can help to decrease the size of lesions and/or decrease itching in patients with MF or SS. The safety of curcumin will also be studied.
- Trial name
- NCT00969085
- Testing
- Curcumin (Turmeric), Questionnaires, Photos
- Sponsor
- M.D. Anderson Cancer Center
Pediatric Patients Having Renal Failure and on Regular Hemodialysis
Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study
The study will be a randomised, double blinded, placebo controlled design. It will include 2 groups : trial group and placebo group Patients in both groups are children on regular hemodialysis The patients in the trial group will…
- Trial name
- NCT05627843
- Testing
- Curcumin capsules 1 gm
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Radiation-Induced Mucositis, Head and Neck Cancer
Curcumin Gel On Radiation Induced Oral Mucositis
The goal of this clinical study is to investigate the effect of a curcuma longa oral gel (curenext) on reducing radiation-induced oral mucositis severity in cancer patients and provide a context for understanding if there is a…
- Trial name
- NCT05982197
- Testing
- Curcumin Gel, Standard Preparation
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Periodontitis
Efficacy of Curcumin Gel Combined With Non-surgical Periodontal Therapy on Salivary Procalcitonin Level in the Treatment of Periodontitis Patients
Objectives: To evaluate the efficacy of curcumin gel as an adjunct to scaling and root planing (SRP) on the salivary procalcitonin level in the treatment of periodontitis.
- Trial name
- NCT05667376
- Testing
- Local drug delivery, curcumin gel
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Reham abdelfatah
Psoriasis
Turmeric Based Therapy in the Treatment of Psoriasis: A Clinical Trial
Psoriasis affects around 4% of world population. The disease could be disabling and disfiguring dermatologic condition. World Health Organization (WHO) has recently drawn the attention to the inadequate treatment options…
- Trial name
- NCT04071106
- Testing
- Turmeric Extract, Turmeric Extract in Olive oil, Petrolatum
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Lupus Nephritis, SLE Nephritis
The Effect of Curcumin on the Clinical Outcome of Pediatric Patients with Active Lupus Nephritis
Pediatric Lupus nephritis which is a sever and common complication to childhood onset systemic lupus erythematous is an aggressive inflammatory process triggered by the deposition of antigen-antibody complex in kidney tissue.
- Trial name
- NCT05714670
- Testing
- Curcumin Oral Capsule
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Prostate Cancer
Nanocurcumin for Prostate Cancer Patients Undergoing Radiotherapy (RT)
There is a growing body of evidence exploring the role of curcumin as a radioprotector against radiation-induced injury in normal tissues as well as a radiosensitizer in tumor cells.
- Trial name
- NCT02724618
- Testing
- Curcumin, RT
- Where
- Iran
- Volunteers
- 64 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Bipolar Disorder
Adjunctive Curcumin for Symptomatic Adolescents With Bipolar Disorder: Brain and Body Considerations
This study will enroll 30 adolescents with bipolar disorder (BD) who are suffering from symptoms of depression despite already taking a traditional mood-stabilizing medication.
- Trial name
- NCT01928043
- Testing
- Curcumin
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Sunnybrook Health Sciences Centre
Optic Atrophy, Hereditary, Leber
A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)
Background Leber's Hereditary Optic Neuropathy (LHON) is a maternally inherited ocular disorder associated with a mutation in mtDNA .
- Trial name
- NCT00528151
- Testing
- curcumin
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mahidol University