Clinical trials: Complication of Renal Dialysis
End Stage Renal Disease
Prognostic Value of Central and BracHial Ambulatory Blood Pressure Monitoring in ERSD Patients Treated With HeMOdialysis
This is a prospective cohort study which aims to explore the significance of brachial and central ambulatory blood pressure monitoring in predicting cardiovascular risk in patients with end stage renal disease who are treated…
- Trial name
- C-HEMO (NCT03306160)
- Testing
- 48-hour blood pressure ambulatory monitoring
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Shanghai 10th People's Hospital
Hemodialysis Complication
Retrospective Survey of Hyperkalemia in Hemodialysis
This study aim to describe hyperkalemia clinical burden and investigate the risk factors associated with the burden on HD facility level.
- Trial name
- Visualize-HD (NCT05020717)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Peking University People's Hospital
Secondary Hyperparathyroidism
Cinacalcet in Paediatric Secondary Hyperparathyroidism (SHPT) Due to Chronic Kidney Disease (CKD)
Twelve-month, multicenter, intra-subject controlled (retrospective-prospective), open-label, active-treatment study to evaluate the dose-response and pharmacokinetics (PK) of cinacalcet HCl for the treatment of Secondary…
- Trial name
- NCT01479088
- Testing
- Cinacalcet HCl
- Where
- 5 sites in Italy
- Volunteers
- 30 people
- Sponsor
- ENRICO VERRINA
End Stage Renal Disease
Peridialysis Project: The Influence of Predialysis Factors on the Initial Course of Dialysis
The present study plans to delineate the clinical, biochemical, sociological and psychological factors. involved in dialysis preparation, and their impact on dialysis initiation (DI), modality choice and prognosis.
- Trial name
- Peridialysis (NCT02488200)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Herlev Hospital
End Stage Renal Disease, Dialysis
Peritoneal Membrane Dysfunction in Peritoneal Dialysis Using Metabolomics
Ability and sensitivity of metabolomics analysis to highlight biomarkers or a score of biomarkers that will be able to identify those pediatric patients on peritoneal dialysis at high risk for possible peritoneal dialysis…
- Trial name
- NCT03964701
- Testing
- no intervention
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Baxter (Hellas) Ltd
Renal Failure
Music Interventions for Patients Undergoing Hemodialysis
Fatigue is found to be one of the most persistent problems among patients in treatment with hemodialysis, and associated with impaired health-related quality of life.
- Trial name
- NCT04959682
- Testing
- Music Intervention
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- University of Southern Denmark
Chronic Kidney Disease Requiring Hemodialysis
The Effect of Peer Support on Disease Adaptation and Self-Care Ability in Individuals Diagnosed With Chronic Kidney Failure
This study was designed as an interventional, pretest-posttest controlled trial to examine the effects of peer interaction on disease adaptation and self-care ability in patients newly diagnosed with chronic kidney failure and…
- Trial name
- Peer support (NCT07125976)
- Testing
- peer support
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- pınar dogan
End-stage Kidney Disease, End-stage Renal Disease
The Prevalence of Sarcopenia in a Cohort of Haemodialysis Patients and Its Correlation With Mortality
The study aims to explore the correlation between the prevalence of sarcopenia and one year mortality amongst patients on maintenance hemodialysis
- Conditions
- End-stage Kidney Disease, End-stage Renal Disease, Dialysis Dependent Chronic Kidney Disease, Sarcopenia
- Trial name
- NCT06477978
- Testing
- Hand grip function testing
- Where
- Egypt
- Volunteers
- 274 people
- Sponsor
- Kasr El Aini Hospital
Chronic Kidney Disease (CKD), Secondary Hyperparathyroidism (SHPT)
A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)
The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of ages 0 to 9 years with SHPT associated with stage 5 CKD receiving Peritoneal…
- Trial name
- NCT04064827
- Testing
- Paricalcitol
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 2 people
- Sponsor
- AbbVie
Secondary Hyperparathyroidism
A Phase 3 Study of Etelcalcetide in Children With Secondary Hyperparathyroidism Receiving Hemodialysis
Assess the efficacy, safety, pharmacokinetics (PK) and pharmacodynamics (PD) of etelcalcetide in the treatment of secondary hyperparathyroidism (SHPT) in pediatric participants between ≥ 2 to < 18 years of age, with chronic…
- Trial name
- NCT03969329
- Testing
- Etelcalcetide
- Where
- 23 sites in Belgium, Czechia and 10 more
- Volunteers
- 24 people
- Sponsor
- Amgen
Hemodialysis Complication
Auricular Acupressure and Fluid Restriction Program on Salivary Flow and Fluid Adherence in Children on Hemodialysis
This study aims to evaluate the effects of auricular acupressure on salivary flow rate and fluid restriction adherence among children undergoing Hemodialysis .
- Trial name
- NCT06562959
- Testing
- Fluid Restriction Program, Intervention Bundle (Fluid Restriction Program and Auricular Acupressure
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Uremia, End Stage Renal Disease on Dialysis
Independent Effects of Visceral Adipose Volume and Density on Patient Survival in Peritoneal Dialysis
It was VAT volume predict patient outcome, while VAT density predicted baseline membrane function in PD patients and reflected peritoneal vascular density and local inflammation status.
- Trial name
- NCT07086430
- Volunteers
- 358 people
- Sponsor
- RenJi Hospital
Hyperphosphatemia, Chronic Kidney Disease, Receiving Dialysis
A Study of a Novel Iron-based Phosphate Binder AP301 in Patients With Hyperphosphatemia in the U.S. and China
The goal of this clinical trial is to learn if AP301 could work in the patients receiving maintenance dialysis with elevated blood phosphate.
- Conditions
- Hyperphosphatemia, Chronic Kidney Disease, Receiving Dialysis, ESRD (End-Stage Renal Disease), Dialysis
- Trial name
- RESPOND-2 (NCT06933472)
- Testing
- AP301, AP301 Low Dose
- Where
- 42 sites in United States, China
- Volunteers
- 264 people
- Sponsor
- Alebund Pharmaceuticals
Chronic Kidney Disease, Dialysis
Dose-finding Study of MCI-196
The Primary Objective of this study is to determine the initial starting doses of colestilan (MCI-196) in paediatric subjects with Chronic Kidney Disease Stage 5 on Dialysis and with Hyperphosphataemia.
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia, Paediatric
- Trial name
- NCT01814904
- Testing
- colestilan-L, colestilan-M, colestilan-H
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Kidney Disease
Patient INformation About Options for Treatment - PINOT
This prospective observational study is designed to find out what treatment options new patients with chronic kidney disease learn about from their renal unit.
- Trial name
- PINOT (NCT01298115)
- Where
- Australia
- Volunteers
- 721 people
- Sponsor
- University of Sydney
End-Stage Renal Disease
Morbidity, Mortality, Short and Long-term Survival of Hemodialysis End-stage Kidney Disease Patients in Central Tanzania
Background: In the last 2 decades, Tanzania made great improvements in the renal replacement therapy infrastructure and services.
- Trial name
- NCT03988491
- Where
- Tanzania
- Volunteers
- 10,000 people
- Sponsor
- Benjamin Mkapa Hospital
Anaemia
Anemia Studies in CKD: Erythropoiesis Via a Novel PHI Daprodustat - Pediatric (ASCEND-P)
This is an international, multicenter trial, evaluating pharmacokinetics (PK) (4 weeks), safety (52 weeks), and hemoglobin (Hgb) response (52 weeks) to daprodustat in children and adolescent participants with anemia associated…
- Trial name
- ASCEND-P (NCT05682326)
- Testing
- Daprodustat
- Where
- 4 sites in Japan, South Korea
- Volunteers
- 4 people
- Sponsor
- GlaxoSmithKline
End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis
EXtension of Tablo TrEatmeNt Duration Registry
Observational, retrospective and prospective, multicenter, post-market study of the Tablo Hemodialysis System in hospitalized participants with End-Stage Kidney Disease or Acute Kidney Injury who are prescribed renal replacement…
- Conditions
- End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis, Acute Kidney Injury
- Trial name
- XTEND (NCT04912050)
- Testing
- Tablo Hemodialysis System
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Outset Medical
Chronic Renal Failure, Peritoneal Membrane Disorder
Administration of pH-Neutral Peritoneal Dialysis Solutions Containing Lactate or Bicarbonate in Children
Peritoneal Dialysis (PD) is the preferred treatment modality in children with end-stage renal disease. Unfortunately progressive alterations of the peritoneal membrane occur with time on PD, leading to a continuous loss of…
- Trial name
- BIOKID (NCT01632046)
- Testing
- lactate and bicarbonate buffered dialysis solutions
- Where
- 7 sites in Austria, Finland and 3 more
- Volunteers
- 42 people
- Sponsor
- Heidelberg University
Kidney Disease, Chronc Kidney Disease Stage 5
The Effect of Patient Empowerment Learning (With AI) About Itching in Hemodylasis Patients.
This study investigates whether artificial intelligence-supported patient education can reduce itching and improve patient empowerment in individuals with chronic kidney disease undergoing hemodialysis.
- Conditions
- Kidney Disease, Chronc Kidney Disease Stage 5, Chronic Kidney Disease
- Trial name
- NCT07740083
- Testing
- Artificial Intelligence-Supported Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Izmir Tinaztepe University