Clinical trials: Cognitive Function
Atherosclerosis
ELITE: Early Versus Late Intervention Trial With Estradiol
The purpose of this study is to examine the effects of oral 17B-estradiol (estrogen) on the progression of early (subclinical) atherosclerosis and cognitive decline in healthy postmenopausal women.
- Trial name
- NCT00114517
- Testing
- 17B-estradiol
- Where
- United States
- Volunteers
- 643 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Epilepsy, Cognitive Function 1, Social
The Effect of Dual Task on Postural Control in Children Diagnosed with Epilepsy
An individual's postural control is often accompanied by other tasks in daily life, such as cognitive tasks. Cognitive dual task (cognitive dual task) is the ability to perform two or more cognitive and motor activities…
- Conditions
- Epilepsy, Cognitive Function 1, Social, Balance; Distorted, Children
- Trial name
- NCT06529133
- Testing
- Evaluation of postural control
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Stroke, Acute
Health Disparities in Stroke Patients and Their Families: a Longitudinal Multicenter Study (HDSS)
The meeting point of the patient and his/her immediate family with the health care system is complicated and traumatic. While having to deal with medicalization geared towards providing evidence-based and cost-effective medical…
- Trial name
- HDSS (NCT03330652)
- Where
- 4 sites in Israel
- Volunteers
- 600 people
- Sponsor
- Sheba Medical Center
Activity, Motor
Feasibility and Fidelity of a Gross Motor-based Physical Activity Intervention on Cognition in Preschool-age Children
The goal of this study will be to examine the implementation and preliminary efficacy of a teacher taught gross motor skill-based physical activity (PA) intervention on cognitive variables in low low socio-economic (SES)…
- Trial name
- P-MAC (NCT05949866)
- Testing
- Movement and Cognition Intervention Group, Health Tracker Group (Control Group)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Healthy, Child Development
Event Related Potentials in Infants and Adults
This study will explore the development of visual perception and the brain activity that underlies it. It will examine electrical activity in the brain while people are processing characteristics of the visual environment, and…
- Trial name
- NCT00088712
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Depressive Disorder in Mothers
Treatment of Depression in Mothers in Home Visitation
This study develops and contrasts In-Home Cognitive Behavioral Therapy (IH-CBT), an adapted evidence-based treatment for depressed mothers participating in home visitation, with typical home visitation in which treatment may be…
- Trial name
- MIDIS (NCT01221701)
- Testing
- In-Home Cognitive Behavioral Psychology
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acne Vulgaris
A Pilot Study of the Effects of Isotretinoin on Cognition, Learning and Memory
This prospective study tested the effects of isotretinoin in a cohort of patients receiving standard therapy for acne vulgaris. Subjects completed questionnaires and standardised computer based cognitive testing using CANTAB to…
- Trial name
- NCT01404130
- Testing
- Isotretinoin
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- University of Aberdeen
Autism
Social Cognition in Children and Adolescents With Autism Spectrum Disorder
This study aims to (1) characterize the multi-domain social cognitive profile and developmental trajectory of children with autism spectrum disorder (ASD) aged 2.5 to 14 years relative to typically developing peers; (2) establish…
- Trial name
- NCT07692022
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Physical Activity, Obesity
Effectiveness of MOVI Interventions on Adiposity, Cognition and Subclinical Atherosclerosis: MOVI-daFit!
Project which objective is to test the effectiveness of an extracurricular physical activity intervention based on high intensity interval training (MOVI-daFit!) on improving cardiorespiratory fitness (CRF), cardiometabolic risk…
- Conditions
- Physical Activity, Obesity, Children, Cardiovascular
- Trial name
- NCT03236337
- Testing
- MOVI intervention
- Where
- 2 sites in Spain
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Cardiometabolic Health, Gastro-intestinal Wellbeing
Effects of Wholegrains on Children's Health (KORN)
KORN investigates the effects of wholegrain oat and rye intake on health and cognitive wellbeing in children with overweight.
- Conditions
- Cardiometabolic Health, Gastro-intestinal Wellbeing, Cognitive Function, Overweight
- Trial name
- NCT04430465
- Testing
- Grain products high in wholegrains from oat and rye, Grain products low in wholegrains
- Where
- Denmark
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cerebrovascular Accident
Effects of Combined Resistance and Aerobic Training vs Aerobic Training on Cognition and Mobility Following Stroke
Both aerobic training (AT) and resistance/strength training (RT) have the potential to improve recovery after stroke. Research conducted in chronic disease and healthy populations suggest that AT and RT "combination therapy" may…
- Trial name
- TRI-RAvA (NCT01712724)
- Testing
- combined resistance and aerobic training
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- University Health Network, Toronto
Cognitive Impairment, Child Autism
Exercise and Cognition in Children With ASD
Physical exercise is widely reported to be beneficial to executive functions (EFs) in children with autism spectrum disorder (ASD).
- Trial name
- NCT05503459
- Testing
- Bicycle learning, Stationary cycling
- Where
- Hong Kong
- Volunteers
- 82 people
- Sponsor
- Education University of Hong Kong
Cognitive Function 1, Social
The Cogni-Action Project: Physical Activity, Brain, and Cognition
Education and health are crucial topics for public policies as both largely determine the future wellbeing of the society. Currently, several studies recognize that physical activity (PA) benefits brain health in children.
- Trial name
- Cogni-Action (NCT03894241)
- Testing
- physical activity
- Where
- 2 sites in Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Valparaiso
Cognition
Pilot Study of Active Desk in Primary School : Effects on Cognitive Capacities, Physical Capacities and Well-being
Physical activity (PA) is insufficient in children with three quarters of them who do not meet the WHO's recommendations. Physical inactivity is growing during adolescence; in part due to the time spend in sedentary behaviors at…
- Trial name
- BICLASS (NCT04880759)
- Testing
- bike desks in the classroom
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Alzheimer's Disease
OmegAD (Omega-3 and Alzheimer's Disease)
Memory loss and difficulties with thinking associated with Alzheimer's disease (AD) may be due to a deficiency in the brain of a fatty acid named DHA.
- Trial name
- NCT00211159
- Testing
- EPAX 1050TG
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Karolinska University Hospital
Memory, Learning
Examining the Effects of a Team-based Running Program
The investigators are interested in finding accessible interventions for youth and young adults that help promote long-term positive mental health functioning.
- Conditions
- Memory, Learning, Mood, Attention
- Trial name
- NCT03143582
- Testing
- Running
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Attention-deficit Hyperactivity Disorder
Cognitive Restructuring in ADHD: Functional Training
The objective of the Cognitive Restructuring in ADHD: Functional Training (CRAFT) study is to develop a non-pharmacological intervention program for children with Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- CRAFT (NCT02827188)
- Testing
- Mega Team-videogame
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- The Hospital for Sick Children
Neurofibromatosis Type 1
Effect of Lamotrigine on Cognition in NF1
The purpose of this study is to determine whether lamotrigine can improve cognitive and neurophysiological deficits in adolescents with Neurofibromatosis type 1.
- Trial name
- NF1-EXCEL (NCT02256124)
- Testing
- Lamotrigine
- Where
- 3 sites in Belgium, Netherlands and 1 more
- Volunteers
- 41 people
- Sponsor
- Erasmus Medical Center
Cerebral Palsy
Amantadine in Treating Cognitive & Motor Impairments in Adolescents and Adults With Cerebral Palsy
Cerebral palsy (CP) is a common childhood-onset disability associated with motor and cognitive impairments, however most research is focused on motor outcomes.
- Trial name
- NCT04273737
- Testing
- Amantadine Hydrochloride
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Columbia University
RETT Syndrome With Proven MECP2 Mutation
Repurposing Mirtazapine in Rett Syndrome
Rett Syndrome (RTT) is a rare neurodevelopmental disorder caused by an MECP2 gene mutation on the X chromosome, primarily affecting females.
- Trial name
- MirtaRett (NCT07430046)
- Testing
- mirtazapine
- Where
- 4 sites in Italy
- Volunteers
- 54 people
- Sponsor
- University of Trieste
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