Clinical trials: Cognitive Function
Prodromal Schizophrenia, Prodromal Psychosis
Aripiprazole Treatment of the Prodrome
The RAP Program is conducting a research study of the antipsychotic medication Aripiprazole. This drug has been approved for treating symptoms associated with schizophrenia and is associated with fewer side effects.
- Trial name
- NCT00169949
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwell Health
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Complex Neurodevelopmental Disorder
Cognitive Benefit of Intensive Rehabilitation Using Rhythmic Music Training in Children With Complex Neurodevelopmental Disorder
In the wide range of studies carried out on neurodevelopmental disorders (NDD), rhythm disorders have been identified as a major cross-cutting component.
- Trial name
- CHUpercu (NCT07303049)
- Testing
- Intensive rhythmic musical training
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Toulouse
Haemophilia A, Haemophilia B
A Study of the Impact of Hemophilia and Its Treatment on Brain Development, Thinking and Behaviour in Children With Hemophilia
The Hemophilia Growth and Development Study (HGDS) nearly 25 years ago showed haemophilia and HIV impacted brain development, thinking, and behaviour in children and adolescents.
- Trial name
- eTHINK (NCT03660774)
- Testing
- No treatment given
- Where
- 22 sites in United States
- Volunteers
- 563 people
- Sponsor
- Novo Nordisk A/S
HIV Infections
Perspective Memory and Executive Functions in HIV+ Patients
The primary goal of this observational study is to evaluate prospective memory in HIV+ patients compared to healthy subjects. The secondary goal is to examine the relationship between prospective memory and Hot Cognition…
- Trial name
- (3514) (NCT05752578)
- Testing
- Neuropsychological testing
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cognitive Decline
Mind-motor Exercise to Improve Cognition and Functional Fitness
This is a 3 month cluster randomized controlled trial using a square-stepping exercise program (a.k.a. mind-motor exercise) in retirement and long-term care residences to improve global cognitive functioning in older adults with…
- Trial name
- MIND-FUN (NCT02730013)
- Testing
- Square Stepping Exercise
- Where
- Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Western Ontario, Canada
Huntington Disease
Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease
WVE-HDSNP2-002 is an open-label extension (OLE) study to evaluate the safety, tolerability, PK, PD, and clinical effects of WVE-120102 in adult patients with early manifest HD who carry a targeted single nucleotide polymorphism…
- Trial name
- NCT04617860
- Testing
- WVE-120102
- Where
- 20 sites in Australia, Canada and 5 more
- Volunteers
- 36 people
- Sponsor
- Wave Life Sciences USA, Inc.
Persisting Primitive Reflexes
Preschool Children Motor Development
The preschool age period is crucial for motor and cognitive development, which retention primary reflexes can negatively influence.
- Trial name
- NCT06071000
- Testing
- Neuro-developmental stimulation (Neuro-vývojová stimulace).
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Autism
Therapeutic Intervention Effects of rTMS on Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a common and complex neurodevelopmental disorder, which is characterized by impairments of social communication, social reciprocity, as well as restricted and repetitive behaviors (RRB).
- Trial name
- NCT05140356
- Testing
- Applied high amplitude repeated transcranial magnetic stimulation, Applied low amplitude repeated transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- University of Electronic Science and Technology of China
Depressive Disorder in Mothers
Treatment of Depression in Mothers in Home Visitation
This study develops and contrasts In-Home Cognitive Behavioral Therapy (IH-CBT), an adapted evidence-based treatment for depressed mothers participating in home visitation, with typical home visitation in which treatment may be…
- Trial name
- MIDIS (NCT01221701)
- Testing
- In-Home Cognitive Behavioral Psychology
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Attention Deficit, Mobility
Cognitive and Postural Activities of Prematurely Born Children
Prematurely born children (PC) have academic difficulties related to poorer attention capabilities. Additionally, they often show excessive mobility, quoted as agitation.
- Conditions
- Attention Deficit, Mobility, Postural Activity
- Trial name
- COGNIPOST (NCT04275895)
- Testing
- Evaluation of different attention or/and postural activities
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Learning Disorders, Depression
Move and Feel Good : Effects of Intensive Physical Training on Brain Plasticity, Cognition and Psychological Well-being.
The investigators perform a prospective, randomized, clinical study involving students in education with mood disorders and randomized to an intensive exercise program or a control relaxation activity.
- Conditions
- Learning Disorders, Depression, Anxiety
- Trial name
- Move&FG (NCT02970825)
- Testing
- Exercise, Relaxation
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Child Development
The Role of Motion in Infants' Ability to Categorize
This study is concerned with psychological and physiological development in infants. Specifically, researchers are interested in when and how babies are able to group similar objects, like animals or vehicles, into the same…
- Trial name
- NCT00362076
- Where
- United States
- Volunteers
- 941 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Academic Acheivement, Physical Activity
Effects of Physical Activity on Math - an RCT
Background Increased physical activity can improve cognition and academic skills. However due to economic concerns and increasing focus on standardized testing, PA in schools often receives little attention and physical education…
- Trial name
- NCT02488460
- Testing
- Physically active math lessons
- Volunteers
- 545 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Motor Development, Balance
Balance-Cognitive-Strength Training for Balance, Inhibitory Control, and Gait in Preschool Children
This randomized controlled study evaluated whether an 8-week balance-cognitive-strength training program improved balance ability, inhibitory control, and gait performance in preschool children aged 3 to 6 years.
- Conditions
- Motor Development, Balance, Healthy Children, Gait
- Trial name
- BCS-Preschool (NCT07689474)
- Testing
- Balance-Cognitive-Strength Training
- Where
- China
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Malaria
School Based Malaria Control in Ugandan Schoolchildren
The investigators hypothesize that schoolchildren treated with IPT using DP over one year of follow-up will have a different risk of clinical malaria compared to those treated with placebo.
- Trial name
- SBMC (NCT01231880)
- Testing
- Four monthly IPT with dihydroartemisinin Piperaquine (DP), Monthly IPT using DP
- Where
- Uganda
- Volunteers
- 740 people, healthy volunteers welcome
- Sponsor
- Makerere University
Cognitive Impairment, Physical Disability
Circle Game Collaborative--Freddie the Frog
Families who have children with disabilities experience more challenges in interacting with their children than families who have children without disabilities.
- Trial name
- NCT05522946
- Testing
- Gameplay between parent and child or adolescent with or without a disability
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio State University
Mild Cognitive Impairment, Alzheimer Disease
Effect of LEQEMBI on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer's Disease
This is a proof of concept observational study is to determine if there is correlation between Aβ plaques and vascular findings in the Retina versus brain ARIA.
- Trial name
- NCT06400368
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NeuroVision Imaging
Mild Cognitive Impairment, Alzheimer's Disease
Investigating the Clinical Consequences of Flutemetamol-PET-scanning
The study examines subjects where there might be an indication for Amyloid-PET according to the Criteria defined by the Amyloid Imaging Task Force.
- Conditions
- Mild Cognitive Impairment, Alzheimer's Disease, Dementia
- Trial name
- NCT02353949
- Testing
- Flutemetamol (Vizamyl)
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University of Zurich
Diet Modification
Increasing Lean Protein Intake in Preschool-age Children and Assessing Effects on Cognition and Select Health Outcomes
The proposed project addresses the goal of exploring preschooler's ability to recognize changes in feelings of hunger/satiety based on consuming a snack and a meal (lunch/dinner) that are either based on the usual childcare…
- Trial name
- NCT06882252
- Testing
- Low glycemic index diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sibylle Kranz, PhD, RDN
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