Clinical trials: Clinical Decision Support
Genetic Disease, Pediatrics
Clinical Decision Support to Identify Pediatric Patients With Undiagnosed Genetic Disease
This study will evaluate the effectiveness of SIGHT as a clinical support system to prompt provider/patient discussion and shared decision making regarding the need for genetic testing in the form of a chromosomal microarray.
- Conditions
- Genetic Disease, Pediatrics, Predictive Model, Clinical Decision Support
- Trial name
- SIGHT (NCT06744543)
- Testing
- SIGHT Prompted Provider Message
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanderbilt University Medical Center
Adverse Drug Reactions, Clinical Decision Support
Multi-Agent Collaborative ADR Prediction With Human-Machine Decision Comparison
This study develops a multi-agent collaborative prediction model to forecast adverse drug reactions using real-world clinical medical records.
- Trial name
- NCT07808866
- Testing
- Retrospective medical record data analysis only, no clinical intervention
- Where
- 2 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Peking University Third Hospital
Children With Medical Complexity (CMC), Multiple Chronic Conditions
Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis
The goal of this pilot hybrid type I efficacy/implementation trial is to assess a newly developed decision support tool patients, parents, and providers to use during surgical treatment decision making for neuromuscular scoliosis…
- Conditions
- Children With Medical Complexity (CMC), Multiple Chronic Conditions, Neuromuscular Scoliosis, Shared Decision Making
- Trial name
- NCT07167927
- Testing
- Decision support tool
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Utah
Emergency Care, Clinical Decision Support
Artificial Intelligence(AI) in the Emergency Department (ED) in Cologne
This retrospective, non-interventional study evaluates the prognostic performance of open-weight Large Language Models (LLMs) in the setting of a German academic emergency department.
- Conditions
- Emergency Care, Clinical Decision Support, Triage
- Trial name
- KINA-CO (NCT07725965)
- Where
- Germany
- Volunteers
- 100,000 people
- Sponsor
- University of Cologne
Preeclampsia, Aspirin
Low Dose Aspirin Alerts in High-Risk Pregnancies
The goal of this study is to assess the effect of an electronic health record (EHR) clinical decision support tool, also known as a best practice alert (BPA), on healthcare provider recommendations for low dose aspirin use in a…
- Conditions
- Preeclampsia, Aspirin, Clinical Decision Support Systems, Economics, Behavioral
- Trial name
- NCT05802940
- Testing
- Electronic health record best practice alert
- Where
- United States
- Volunteers
- 830 people
- Sponsor
- Geisinger Clinic
Trauma, Injury
Clinical Evaluation of an AI Risk Prediction System (AI-TRiPS)
The goal of this clinical study is to evaluate a software device and its impact on clinician behaviour during the initial management of trauma patients in a real-world clinical setting.
- Conditions
- Trauma, Injury, Decision Support Systems, Clinical
- Trial name
- AI-TRiPS (NCT07634185)
- Testing
- AI-TRiPS Device
- Volunteers
- 1,200 people
- Sponsor
- Queen Mary University of London
Pain Management, Pain Assessment
Effectiveness and Implementation of a Clinical Pain Management Dashboard for the NICU
This study protocol describes a type 1 hybrid effectiveness-implementation study evaluating a clinical decision support dashboard for neonatal pain management in a tertiary NICU.
- Conditions
- Pain Management, Pain Assessment, Neonatal Intensive Care, Implementation Research
- Trial name
- NCT07629661
- Testing
- Implementation of clinical pain management dashboard
- Where
- Netherlands
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Clinical Decision Support System (CDSS)
A Qualitative Study Examining Clinical Decision Support System Adoption Among Hospital Clinicians
A Qualitative Study to Explore the Barriers to Adoption of Clinical Decision Support Systems
- Trial name
- CDSS-ADOPT (NCT07398235)
- Testing
- Semi-structured interview
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Medway NHS Foundation Trust
Clinical Decision Support System
ICU Cockpit Apps: Interventional Study With First ICU Cockpit Software Applications
In neurocritical care, besides the standard intensive care monitoring, even more data are obtained from the very complex pathophysiological changes in brain disease.
- Trial name
- ICUCockpiApp (NCT04748289)
- Testing
- ICU Cockpit software testing
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- Emanuela Keller
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Clinical Decision Support Systems
Medical Imaging Decision And Support
Rationale: Diagnostic medical imaging is essential in health care and guides patient management decisions. Rapid advances in imaging technology have enabled diagnosis at an early disease stage.
- Trial name
- MIDAS (NCT05490290)
- Testing
- Active
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- University Hospital Augsburg
Brain Injury, Clinical Decision Support
Implementation of the Pittsburgh Infant Brain Injury Score
This is an implementation study of the Pittsburgh Infant Brain Injury Score (PIBIS) into the UPMC Children's Hospital of Pittsburgh emergency department.
- Conditions
- Brain Injury, Clinical Decision Support, Infant
- Trial name
- PIBIS (NCT05034718)
- Testing
- PIBIS clinical decision support, Standard of care
- Where
- United States
- Volunteers
- 1,989 people
- Sponsor
- University of Pittsburgh
Clinical Decision Support
Optimizing the Influenza Clinical Decision Support Tool
The proposed study aims to examine several iterations of the Influenza Best Practice Alert at NYU Langone Health. The goal is to increase ordering of the influenza vaccine through the alert.
- Trial name
- NCT03415425
- Testing
- Current Version of the Influenza Alert, Alternate Modifications of the Influenza Alert
- Where
- United States
- Volunteers
- 25,881 people
- Sponsor
- NYU Langone Health
Pneumonia, Primary Health Care
Tools for the Integrated Management of Childhood Illness (TIMCI): Evaluation of Pulse Oximetry & Clinical Decision Support Algorithms in Primary Care
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Pneumonia, Primary Health Care, Child Health, Hypoxia
- Trial name
- TIMCI (NCT04910750)
- Testing
- Pulse oximetry, Clinical Decision Support Algorithm
- Where
- 27 sites in Tanzania
- Volunteers
- 167,517 people
- Sponsor
- Swiss Tropical & Public Health Institute
Childhood Severe Illness, Pneumonia
Tools for the Integrated Management of Childhood Illness: Cross-country Quasi-experimental Pre-post Study in Kenya and Senegal
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Childhood Severe Illness, Pneumonia, Primary Health Care, Hypoxia
- Trial name
- TIMCI (NCT05065320)
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 51,590 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Clinical Decision Support, Clinical Practice Guidelines
Professional Development in Emergency Medical Services
The ProDEms-trial focuses on nurses and ambulance drivers working in prehospital care, taking care on the one hand of patients suffering from time-sensitive critical conditions like STEMI, acute stroke or severe traumatic brain…
- Conditions
- Clinical Decision Support, Clinical Practice Guidelines, Emergency Medical Services
- Trial name
- ProDEms (NCT02365792)
- Testing
- Clinical Decision Support Tool for Prehospital Care
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- KU Leuven
Diarrhea Infectious, Algorithms
The Acceptability and Impact of Diarrheal Etiology Prediction (DEP) Algorithm
This is a randomized crossover study, where clinicians will be randomized to periods where they will use a rehydration calculator application with or without the Diarrheal Etiology Prediction (DEP) algorithm.
- Conditions
- Diarrhea Infectious, Algorithms, Decision Support Systems, Clinical, Clinical Decision-Making
- Trial name
- NCT04602676
- Testing
- Rehydration calculator application with DEP algorithm, Rehydration calculator application
- Where
- 2 sites in Bangladesh, Mali
- Volunteers
- 30 people
- Sponsor
- University of Utah
Clinical Decision Support, Medical Informatics Interventions
Showing Health Information Value in a Community Network
The purpose of this study is to determine the value of shared health information on care quality and costs when this information is used to notify care providers about concerning health events for patients cared for by a…
- Conditions
- Clinical Decision Support, Medical Informatics Interventions, Population Health Management, Quality of Healthcare
- Trial name
- NCT00365885
- Testing
- Computer-based clinical decision support.
- Where
- United States
- Volunteers
- 20,108 people
- Sponsor
- Duke University
Decision Support Systems, Clinical
Evidence-Based Medicine Electronic Decision Support Study
The purpose of this study is to analyze the effect of the Evidence-Based Medicine electronic Decision Support (EBMeDS) automatic reminders in primary health care.
- Trial name
- EBMeDS (NCT00915304)
- Testing
- The EBMeDS reminders
- Where
- Finland
- Volunteers
- 12,101 people
- Sponsor
- Tampere University