Clinical trials: Claudication
Intermittent Claudication
(Cost) Effectiveness Study of Exercise Therapy in Patients With Peripheral Arterial Disease
The purpose of this study is to determine if supervised exercise therapy in a physiotherapeutic setting, with or without therapy feedback, is more (cost-)effective than exercise therapy based on a 'go home and walk' advice…
- Trial name
- EXITPAD (NCT00279994)
- Testing
- Exercise therapy, Accelerometer (PAM; Personal Activity Monitor), Oral Exercise Therapy advise
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Atrium Medical Center
Diabetic Angiopathies, Intermittent Claudication
Trial Comparing Different Medical Devices for Infragenual Dilatation
This study is a comparison of different medical devices for infragenual dilatation.
- Trial name
- NCT00134277
- Testing
- Infragenual dilatation, Infragenual dilatation with stenting, Infragenual dilatation with cutting balloon
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- University Hospital, Ghent
Cardiovascular Disease
Evaluation of Patients With Heart Disease Not Eligible for Research Protocols
An important mission of the National Institutes of Health (NIH) is to develop and carry out research studies designed to improve understanding of disease processes and treatments.
- Trial name
- NCT00001458
- Where
- United States
- Volunteers
- 7,829 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Spinal Stenosis
The Coflex®COMMUNITY Study: An Observational Study of Coflex® Interlaminar Technology
The purpose of the coflexCOMMUNITY observational study is to collect information on patients with spinal stenosis undergoing back surgery with the coflex® implant, and to look at their outcomes and the cost-effectiveness of this…
- Trial name
- NCT02457468
- Testing
- coflex
- Where
- 28 sites in United States
- Volunteers
- 325 people
- Sponsor
- Predicted, Reported and Observed Outcomes Foundation
Intermittent Claudication, Peripheral Arterial Disease
York Study of Unloading Shoes for Vascular Intermittent Claudication
Some people experience a cramp-like leg pain during walking that is relieved only by rest. This is called intermittent claudication (IC) and it is a common symptom of peripheral arterial disease.
- Trial name
- YORVIC (NCT02505503)
- Testing
- Unloading shoes, Unadapted control shoe
- Where
- 2 sites in United Kingdom
- Volunteers
- 38 people
- Sponsor
- York Teaching Hospitals NHS Foundation Trust
Peripheral Arterial Disease, Claudication
THE OMEGA-SPM-DOSE and OMEGA-SPM-PAD: Specialized Pro-Resolving Mediators in Patients With Peripheral Artery Disease
The purpose of this study is to understand the effects of fish oil supplement (containing parts of omega-3 fatty acids) on inflammation.
- Conditions
- Peripheral Arterial Disease, Claudication, Claudication, Intermittent, Vascular Occlusion
- Trial name
- NCT02719665
- Testing
- SPM Emulsion, Dose-modality, SPM Softgel, Dose-Modality
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Femoropopliteal Disease, Intermittent Claudication
Trial of Nonsurgical Treatment of Intermittent Claudication Due to Femoro-popliteal Disease
Intermittent Claudication (IC)is a common condition characterised by pain in the muscles of the legs on exertion caused by "hardening of the arteries" and a reduced blood supply.
- Trial name
- NCT00798850
- Testing
- Percutaneous Transluminal Angioplasty (PTA), Supervised Exercise Programme (SEP), Combined Treatment
- Where
- United Kingdom
- Volunteers
- 178 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Claudication
Intra-arterial Measurement of pO2 in Walking Induced Transient Hack Profiles
Confirm with invasive measurement the presence of a Walking-Induced Transient Hack (WITH) profile
- Trial name
- Initial-VHS (NCT01022606)
- Testing
- Arterial sampling
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Angers
Peripheral Arterial Disease, Claudication
Effects of Passive Muscle Stretching on Vascular Function and Symptoms of PAD
Patients with peripheral arterial disease often have walking impairment due to insufficient oxygen supply to lower extremity skeletal muscle.
- Trial name
- NCT03288181
- Testing
- Muscle Stretch
- Volunteers
- 13 people
- Sponsor
- Tallahassee Research Institute, Inc.
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Intermittent Claudication
The Relationship Between Peripheral Arterial Disease and Mitochondrial Respiratory Capacity
Current evidence cannot explain the clinical features of peripheral arterial disease only from the principle of reduced blood flow.
- Trial name
- NCT02434783
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Atherosclerosis, Peripheral Vascular Disease
Magnetic Resonance Imaging to Detect Blood Vessel Inflammation in Patients Undergoing Peripheral Balloon Angioplasty
This study will examine the use of magnetic resonance imaging (MRI) in detecting blood vessel inflammation. The results of this study may later be applied to diagnosing inflammation of arteries in patients with atherosclerosis…
- Trial name
- NCT00004549
- Testing
- Magnetic resonance imaging
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Peripheral Arterial Disease
Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies
Intermittent claudication afflicts 5% of the US population older than 55 years of age and develops along with hardening of the arteries of the legs.
- Trial name
- NCT01970332
- Testing
- Revascularization Surgery, Supervised exercise therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Nebraska
Peripheral Arterial Disease
Effect of Exercise Training on Protein Expression in Skeletal Muscle Tissue After Exercise in Peripheral Arterial Disease
Cardiovascular disease remain one of the leading causes of death in Australia, accounting for 47637 (36%) of deaths in 2004. Peripheral arterial disease (PAD) is a category of cardiovascular disease, characterised by intermittent…
- Trial name
- NCT01871779
- Testing
- Standard Treadmill Exercise, Intermittent treadmill & resistance training
- Where
- Australia
- Volunteers
- 35 people
- Sponsor
- Flinders University
Intermittent Claudication, Peripheral Arterial Disease
Using KomPas+ in the Treatment of Patients With Intermittent Claudication
Intermittent claudication is the most common symptom of peripheral arterial disease (PAD). The recommended therapy is supervised exercise therapy combined with lifestyle counselling, provided by a physiotherapist.
- Trial name
- NCT05232474
- Testing
- KomPas+, KomPas
- Where
- Netherlands
- Volunteers
- 2,271 people
- Sponsor
- Radboud University Medical Center
Peripheral Vascular Diseases, Intermittent Claudication
PTA vs. Primary Stenting of SFA Using Self-Expandable Nitinol Stents
The investigators evaluated whether primary implantation of a self-expanding nitinol stent yielded anatomical and clinical benefits superior to those afforded by percutaneous transluminal angioplasty with optional secondary…
- Conditions
- Peripheral Vascular Diseases, Intermittent Claudication, Angioplasty
- Trial name
- NCT00715416
- Testing
- Nitinol stent, Nitinol Stent Placement
- Where
- Austria
- Volunteers
- 76 people
- Sponsor
- Vienna General Hospital
Limping
High Resolution IR Imaging for Diagnosis in the Acute Limping Child - ThermLimp
A variety of different diseases may cause a limp in a child, and in younger children it is particularly challenging to isolate the area affected.
- Trial name
- Thermlimp (NCT03312348)
- Testing
- Infrared imaging
- Volunteers
- 30 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Intermittent Claudication
Hospital- and Home-based Supervised Exercise Versus UNsupervised Walk Advice For Patients With InTermittent Claudication
The purpose of this randomized clinical trial is to determine and compare the clinical and cost effectiveness of three methods for exercise therapy as treatment for patients with intermittent claudication.
- Trial name
- SUNFIT (NCT02341716)
- Testing
- WA, SET, HET
- Where
- 2 sites in Sweden
- Volunteers
- 165 people
- Sponsor
- Lennart Jivegård
Intermittent Claudication, Peripheral Vascular Diseases
Autologous Bone Marrow-derived Mononuclear Cells for Therapeutic Arteriogenesis in Patients With Limb Ischemia
The investigators propose confirm and extend the findings of open studies on the apparent efficacy of bone-marrow derived mononuclear cells for the induction of arteriogenesis in patients with severe claudication or critical leg…
- Trial name
- ABC (NCT00539266)
- Testing
- bone marrow derived mononuclear cells
- Where
- Netherlands
- Volunteers
- 108 people
- Sponsor
- Leiden University Medical Center
Peripheral Arterial Disease, Cardiovascular Diseases
Assessing the Feasibility of Including Patients With Peripheral Artery Disease in to an Established Cardiac Rehabilitation Service.
This study will investigate if patients with peripheral artery disease (PAD) can be successfully incorporated into an already existing Cardiac Rehabilitation programme.
- Conditions
- Peripheral Arterial Disease, Cardiovascular Diseases, Intermittent Claudication, Coronary Artery Disease
- Trial name
- NCT03564080
- Testing
- Combined - PAD and CAD
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- University of Salford