Clinical trials: Chronic Tic Disorders
Tourette Syndrome, Chronic Tic Disorder
Anger Control Training for Youth With Tourette Syndrome
This is a clinical study of a cognitive-behavioral therapy known as anger control training in adolescents with Tourette Syndrome and explosive, disruptive behavior.
- Conditions
- Tourette Syndrome, Chronic Tic Disorder, Oppositional Defiant Disorder, ADHD
- Trial name
- NCT00486551
- Testing
- Anger control training
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Yale University
Tourette Syndrome, Tic Disorder, Chronic Motor or Vocal
Open-label MNS for Tourette Syndrome
A recent report (Morera Maiquez et al 2020) described reduced tic severity in people with Tourette syndrome during 1-minute epochs of median nerve stimulation (MNS) at 10 Hz.
- Trial name
- NCT05016765
- Testing
- Active, self-directed electrical stimulation of the median nerve
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Washington University School of Medicine
Tic Disorder
Scalp Acupuncture Treatment for Chronic Tic Disorders in Children
The goal of this clinical trial is to learn if scalp acupuncture works to treat chronic tic disorders (CTD) in children. It will also learn about the safety of scalp acupuncture.
- Trial name
- NCT06924918
- Testing
- Scalp Acupuncture Treatment, Tuina Treatment Group
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Children's Hospital of Fudan University
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
TicHelper: A Computerized Comprehensive Behavioral Intervention for Tics (CBIT)
Tic Disorders (including Tourette Disorder) are relatively common in school-age children and for some children can lead to significant psychosocial and physical impairment and diminished quality of life.
- Trial name
- NCT02413216
- Testing
- TicHelper, Internet Based Resources
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- University of Utah
Tourette Syndrome, Tourette Syndrome in Children
Tourette Discrimination (TD) Stigma Scale
The goal of this qualitative study is to understand the challenges of stigmatization and discrimination in children and young adults with Chronic Tic Disorders (CTD), including Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Tic Disorder, Childhood
- Trial name
- TD (NCT05696769)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Wake Forest University Health Sciences
Tourettes Syndrome, Tic
N-acetylcysteine (NAC) for Children With Tourette Syndrome
Tourette syndrome is a childhood-onset neuropsychiatric disorder characterized by multiple motor and vocal tics that last for at least a year in duration.
- Trial name
- NCT01172288
- Testing
- N-Acetylcysteine (NAC)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Yale University
Tourette Disorder, Chronic Tic Disorder
Dissemination of Comprehensive Behavioral Intervention for Tics (CBIT) to Occupational Therapists: A Feasibility Study
Comprehensive Behavioral Intervention for Tics (CBIT) is an evidence based intervention for tic disorders. A recent scientific review of research priorities completed by the Tourette Syndrome Association recommended widespread…
- Trial name
- NCT02114905
- Testing
- OTs Trained and Deliver CBIT
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Weill Medical College of Cornell University
Tourette Syndrome, Chronic Tic Disorder
Proof of Concept Study of an Oral Orthotic to Reduce Tic Severity in Chronic Tic Disorder and Tourette Syndrome
The purpose of this study is to assess the feasibility of a trial on an oral orthotic for reducing tic severity in children ages 7-25 years with Tourette syndrome (TS) or Chronic Tic Disorder (CTD).
- Trial name
- NCT02067819
- Testing
- Active Oral Orthotic Treatment
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Tic Disorder
Treatment Outcome of Combined Virtual Tic Training in Children and Adolescents With a Chronic Tic Disorder
Tics are unwanted, repetitive movements or sounds that are either simple or complex in appearance. Tic disorders often have a huge impact on children's life.
- Trial name
- NCT04678180
- Testing
- Combined HRT and ERP
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- Aarhus University Hospital
Tourette Syndrome, Tic Disorders
Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
This study will determine the effectiveness of cognitive behavior therapy (CBT) with habit reversal training (HRT) in treating chronic tic disorders (CTDs) in children and adolescents.
- Trial name
- CBIT (NCT00218777)
- Testing
- Comprehensive Behavioral Intervention for Tics
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Tourette Association of America
Tourette Syndrome, Chronic Tic Disorder
Transcutaneous Auricular Vagus Nerve Stimulation for Chronic Tic Disorders/Tourette's Syndrome in Children and Adolescents
The objective of this trial is to evaluate the effect of transcutaneous auricular vagus nerve stimulation compared to sham stimulation in improving chronic tic disorder or Tourette's syndrome in children and adolescents.
- Trial name
- NCT07854665
- Testing
- Transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 124 people
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Tourette's Syndrome, Chronic Motor Tic Disorder
Brain-Behavior Interactions in Tic Suppression
The purpose of this study is to examine how the brain and environment interact to influence children's ability to suppress tics using a medical technology called Transcranial Magnetic Stimulation (TMS).
- Conditions
- Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Vocal Tic Disorder
- Trial name
- NCT02205918
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Tourette's Disorder, Persistent (Chronic) Motor or Vocal Tic Disorder
Internet-delivered Behaviour Therapy for Children and Adolescents With Tourette's Disorder
The purpose of this trial is to evaluate the clinical efficacy, 12-month durability, and cost-effectiveness of BIP TIC - a therapist-guided and parent-guided internet-delivered behavioural intervention for children and…
- Trial name
- NCT03916055
- Testing
- Exposure and response prevention (ERP), Education on tics
- Where
- Sweden
- Volunteers
- 221 people
- Sponsor
- Karolinska Institutet
Chronic Motor or Vocal Tic Disorder, Tourette's Disorder
Aripiprazole in Children and Adolescents With Chronic Tic Disorder or Tourette's Disorder
The purpose of this trial is to demonstrate the efficacy and safety of aripiprazole in children and adolescents aged 6~18 years with chronic tic disorders or Tourette's disorder
- Trial name
- NCT00706589
- Testing
- aripiprazole
- Where
- 6 sites in South Korea
- Volunteers
- 61 people
- Sponsor
- Korea Otsuka Pharmaceutical Co., Ltd.
Tourette Syndrome, Tic Disorders
Effectiveness of Behavior Therapy and Psychosocial Therapy for the Treatment of Tourette Syndrome and Chronic Tic Disorder
This study will compare the efficacy of supportive therapy versus habit-reversal therapy for the treatment of Tourette syndrome and chronic tic disorder.
- Trial name
- NCT00231985
- Testing
- Habit reversal therapy, Supportive therapy
- Where
- 3 sites in United States
- Volunteers
- 122 people
- Sponsor
- Massachusetts General Hospital
Tic Disorder, Tourette Syndrome
Phase III Study of 5LGr to Treat Tic Disorder
The purpose of this study is to evaluate the effective and safety of 5LGr in pediatric patients with tic disorders.
- Conditions
- Tic Disorder, Tourette Syndrome, Chronic Tic Disorder
- Trial name
- 5LGr (NCT01501695)
- Testing
- 5LGr, tiapride
- Volunteers
- 603 people
- Sponsor
- Tasly Pharmaceuticals, Inc.
Tic Disorders
Acupuncture Treatment in Pediatric Patients With Tic Disorders: A Prospective, Single-Center, Randomized Controlled Trial
This study was conducted to observe the efficacy of Nourishing the vital energy and Regulating the spirit needle technique in the treatment of chronic tic disorder through the Yale Global Tic Severity Scale (YGTSS) and the…
- Trial name
- ATPTD (NCT07071428)
- Testing
- Regular acupuncture, the Nourishing the vital energyand Regulating the spirit needle technique
- Where
- China
- Volunteers
- 76 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Tourette's Syndrome, Tourette's Disorder
Psychosocial Intervention for Young Children With Chronic Tics
Analysis of data from the recently completed NIH Child Comprehensive Behavioral Intervention for Tics (CBIT) study found a manualized behavioral treatment approach strongly superior to psychoeducation/supportive therapy for…
- Conditions
- Tourette's Syndrome, Tourette's Disorder, Tourette's Disease, Tourette Disorder
- Trial name
- CBIT JR (NCT03042507)
- Testing
- Comprehensive Behavioral Intervention for Tics (CBIT)
- Volunteers
- 15 people
- Sponsor
- Weill Medical College of Cornell University
Tourette Syndrome, Chronic Tic Disorders
Developing Cognitive Training for Tourette Syndrome
Many researchers suspect that individuals with Tourette Syndrome (TS) may have a poor cognitive ability (i.e., response inhibition; RI) that is essential to inhibit inappropriate response such as vocal or motor tics.
- Trial name
- NCT01440023
- Testing
- Comprehensive Behavioral Intervention for Tics (CBIT), Computerized Response Inhibition Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Milwaukee
Tic Disorders
Mobile App-assisted Behavioral Treatment in Children and Adolescents With Tics
Chronic tic disorders are neurodevelopmental disorders affecting 0.5-1% of children and adolescents. Tics present as sudden, rapid, repetitive non-rhythmic movements or vocalizations or a combination.
- Trial name
- NCT05390268
- Testing
- Mobile app-assisted behavioral treatment, Mobile app-assisted psychoeducation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital