Clinical trials: Child Development
Autism Spectrum Disorder, Autism
Safety and Efficacy of the Transfusion of UCB in Patients With an ASD Depending on the Degree of HLA Compatibility.
Autism is one of those disorders in Autism spectrum disorders (ASD), which characterized by social interaction abnormalities, impaired verbal and non-verbal communication, and repetitive, obsessive behavior, while the therapeutic…
- Trial name
- ASD-HLA2019 (NCT04099381)
- Testing
- ASD CB-MNC infusion low level HLA compatibility., ASD CB-MNC infusion high level HLA compatibility., Standard therapy.
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Autism Spectrum Disorder
Trial of Autism Parent Navigator Program
To address the dual needs of parents for support in navigating Autistic Spectrum Disorder (ASD) services and maintaining positive family functioning, the investigators propose to test Autism Parent Navigators (APN), an innovative…
- Trial name
- APN (NCT04744428)
- Testing
- Autism Parent Navigators, Peer mentoring
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Penn State University
Child Language
Genetic Biomarkers of Child Language Development in Taiwan: an Identification and Validation Study
A study of the relation between genetic biomarkers and child language development in Taiwan.
- Trial name
- NCT05504564
- Testing
- The experiment does not required any intervention
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Parent-Child Relations, Parenting
Literacy Promotion Using Automated Hovering
The purpose of this study is to incorporate behavioral economics (BE) approaches to determine whether 3 novel interventions of varying intensity improve the frequency of parent-child reading behaviors among low-income families.
- Conditions
- Parent-Child Relations, Parenting, Literacy
- Trial name
- LP (NCT04576481)
- Testing
- Texting, Regret, Lottery
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Silver Russell Syndrome, Prader-Willi Syndrome
Aromatase Inhibitor in Bone Maturation, Children With Silver Russell or Prader-Willi Syndrome
There is currently no drug with pediatric marketing authorization capable of limiting the advance in bone maturation of children with aggressive adrenarche.
- Trial name
- ANASILPRA (NCT01520467)
- Testing
- Anastrozole
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorders
Omega-3 Fatty Acids in Autism Spectrum Disorders
This is a 12-week open label trial to evaluate whether omega-3 fatty acids is effective in reducing the severity of autism and its comorbidities.
- Trial name
- NCT01695200
- Testing
- Omega-3 fatty acids
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- National Healthcare Group, Singapore
Child Development
The Effect of Early-life Risk Factors on the Etiology of Diabetes in Children: a Birth Cohort
In recent years, with the rising prevalence of obesity among children, the incidence of type 2 diabetes in children and adolescents has continued to be increased.
- Trial name
- NCT04313998
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sijia Gu
Autism Spectrum Disorder With Intellectual Deficiency
Recording Stress Biomarkers in Autism Spectrum Disorders
The goal of this observational study is to learn how stress affects children and young people with autism spectrum disorder (ASD).
- Trial name
- STRESSDEFIS (NCT07535801)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite Cote d'Azur
Autism Spectrum Disorder
EMPATIA@Lecco- Balance Rehabilitation of Autistic Children With Virtual rEality
The general objective of this project is to investigate the possible efficacy of a training based on proprioceptive and visual feedback carried out with the GRAIL (Motekforce Link) virtual reality environment on postural control…
- Trial name
- BRAVE (NCT04276571)
- Testing
- exergames with GRAIL virtual immersive reality environment
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS Eugenio Medea
Overweight, Autism Spectrum Disorder
Treatment of Overweight Induced by Antipsychotic Medication in Young People With Autism Spectrum Disorders (ASD)
The purpose of this study is to determine whether metformin is safe and effective in the treatment of weight or weight gain in young people with Autism Spectrum Disorders (ASD) who are currently taking atypical antipsychotic…
- Trial name
- MET (NCT01825798)
- Testing
- Metformin
- Where
- 4 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Autism Spectrum Disorder
A Study to Evaluate Scales for Repetitive and Restricted Behaviors in Children, Adolescents, and Adults With Autism Spectrum Disorder (ASD)
This is a non-drug study seeking to characterize different scales to measure repetitive and restrictive behaviors in different ASD sub-populations over time. This study will also explore the use of digital biomarkers.
- Trial name
- NCT03611075
- Testing
- No Intervention
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Opioid Use Disorder, Neonatal Abstinence Syndrome
RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure
The impact of parental opioid use disorder and other substance use exposure on child welfare and the healthcare system is undeniable.
- Conditions
- Opioid Use Disorder, Neonatal Abstinence Syndrome, Child Development, Child Abuse
- Trial name
- RESPECT-Plus (NCT02334111)
- Testing
- RESPECT-Plus
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Medical Center
Malnutrition, Intestinal Diseases, Parasitic
The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas
Worldwide, over 2 billion people suffer from worm infections in developing countries. These infections are especially damaging to the health of children, resulting in both short-term and lifelong disability.
- Trial name
- NCT01314937
- Testing
- Mebendazole, Usual care
- Where
- Peru
- Volunteers
- 1,760 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Huntington's Disease
Child to Adult Neurodevelopment in Gene Expanded Huntington's Disease
Huntington's Disease (HD) is an autosomal dominant disease manifested in a triad of cognitive, psychiatric, and motor signs and symptoms. HD is caused by a triplet repeat (CAG)expansion in the gene Huntingtin (HTT).
- Trial name
- ChANGE HD (NCT01860339)
- Where
- 6 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Peggy C Nopoulos
Motor Development, Physical Activity
Evaluation of the Move 2 Learn (M2L) Program for Young Children
Move 2 Learn (M2L) is a 10-week movement and pre-literacy program for preschool aged children and their parents designed to improve both movement and reading skills as well as support their overall cognitive, physical, and…
- Trial name
- NCT03999619
- Testing
- Move 2 Learn
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Autism, ASD
Fronto-temporal tDCS Mproves Fluency & Empathy in ASD Kids
Interventional, prospective, randomized, double-blind, placebo-controlled and parallel assignment study, in which patients with Autism Spectrum Disorder (ASD) are two types of intervention by transcranial random noise stimulation…
- Trial name
- tDCS25112013 (NCT02004236)
- Testing
- tRNS Fronto-temporal cortex, tRNS over fusiform temporal cortex
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people
- Sponsor
- Spanish Foundation for Neurometrics Development
Surgery in Early Childhood
Surgery in Early Life and Child Development at School-entry: A Population-based Study
The central hypothesis is that surgery and anesthesia exposure in children with immature structural and functional brain development has long-term adverse effects on child development at school-entry compared with children not…
- Trial name
- NCT02595801
- Testing
- Surgery in early childhood
- Where
- Canada
- Volunteers
- 188,628 people
- Sponsor
- The Hospital for Sick Children
Pre-Term, Development, Child
EPIPAGE 2 - 10-year Follow-up (RECONAI PROJECT)
Epipage 2 (Epidemiological study on small gestational ages) is a prospective population-based national cohort implemented to better understand the short, mid and long term future of premature children.
- Trial name
- EPIPAGE2 (NCT05243901)
- Where
- France
- Volunteers
- 2,383 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Learning Problems
Educational Support Interventions for Children in Care
A Randomized controlled study of two different educational support interventions developed for children in foster care (age 6-13).
- Trial name
- NCT02217072
- Testing
- School intervention, Parents as Tutors
- Where
- Denmark
- Volunteers
- 190 people
- Sponsor
- VIVE - The Danish Center for Social Science Research
Autism Spectrum Disorder
Sibling-Mediated Intervention on Literacy and Reciprocity for Children With Autism
Given the increasing prevalence of autism spectrum disorder (ASD), estimated to be 1 in 68 in the United States alone, ASD has become one of the fastest-growing pediatric concerns.
- Trial name
- NCT05098392
- Testing
- Sibling-mediated intervention
- Where
- 3 sites in United States, China
- Volunteers
- 8 people
- Sponsor
- Arizona State University
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