Clinical trials: Cataract Congenital
Congenital Cataract
Reduction of Corneal Astigmatism With Toric Intraocular Lens Implantation in Congenital Cataract
This study was conducted to evaluate changes of reduction of corneal astigmatism with toric intraocular lens(IOL) in congenital cataract.
- Trial name
- NCT02040129
- Testing
- Acrysof Toric IOL
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Kyungpook National University Hospital
Cataract, Glaucoma
Potential Research Participants for Future Studies of Inherited Eye Diseases
This study will evaluate potential candidates for future clinical research studies related to diagnosed or undiagnosed genetic eye disorders or diseases.
- Conditions
- Cataract, Glaucoma, Retinitis Pigmentosa, Macular Degeneration
- Trial name
- NCT00559234
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- National Eye Institute (NEI)
Crystalline Cataract, Lens; Anomaly
Age-related Changes of Crystalline Lens Tilt and Decentration: A Swept-source Optical Coherence Tomography Study
230 participants at Eye Hospital of Wenzhou Medical University during June, 2019 and August, 2019 were enrolled in this study. 230 right eyes and 88 left eyes were included for the measurement.
- Trial name
- NCT04487795
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Yune Zhao
Congenital Cataract
Guangke Lenses in Congenital Cataract
This study aims to investigate whether individually customized bifocal + defocus spectacles can slow myopic shift in children after congenital cataract surgery.
- Trial name
- NCT07778797
- Testing
- Conventional Bifocal Lenses, Individually Customized Bifocal + Defocus Lenses
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cerebrotendinous Xanthomatosis (CTX)
Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Iiopathic bilateral cataracts occur in many children with Cerebrotendinous Xanthomatosis (CTX) so the opportunity to use contact with health care providers in connection with pediatric cataract evaluation and treatment is a…
- Trial name
- NCT02638220
- Where
- 44 sites in United States
- Volunteers
- 442 people
- Sponsor
- Travere Therapeutics, Inc.
Cataract Congenital, Astigmatism
Toric Intraocular Lens Implantation in Pediatric Cataract
To evaluate the visual and refractive outcomes after an intraocular lens (IOL) implantation in pediatric eyes with cataract and preexisting corneal astigmatism
- Conditions
- Cataract Congenital, Astigmatism, IOL
- Trial name
- TILIPC (NCT06294795)
- Testing
- congenital/pediatric cataract surgery, Non-Toric IOLs, Toric IOLs
- Where
- 2 sites in Kazakhstan
- Volunteers
- 40 people
- Sponsor
- Kazakh Eye Research Institute
Congenital Cataract
Electrophysiology in Congenital Cataract After Lensectomy and Anterior
In this prospective study , a cohort of 91 eyes with congenital cataract and 25 eyes normal eyes from Wenzhou medical university was erolled.91 eyes with congenital cataract was after lensectomy and anterior vitrectomy as test…
- Trial name
- NCT04427748
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Congenital Cataract, Aphakic or Pseudophakic Glaucoma
Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients
In cell cultures, lens epithelial cells and trabecular meshwork cells will be exposed to aqueous humor from pediatric eyes undergoing cataract removal surgery.
- Trial name
- NCT01136473
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Carmel Medical Center
Deprivation Amblyopia, Congenital Cataract
Augmented Reality Training for Amblyopia After Congenital Cataract Surgery
This study will evaluate whether augmented reality training is effective and safe for treating unilateral amblyopia after congenital cataract surgery in children.
- Trial name
- NCT07693790
- Testing
- Augmented Reality Amblyopia Training, Conventional Patching
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Non-genetic Risk Factors of Congenital Cataracts
Prevention and treatment of the reversible childhood blindness, including congenital cataracts (CC), has been listed as a significant component of the international programme "VISION 2020 - the Right to Sight" launched by WHO in…
- Trial name
- NCT03215186
- Testing
- observational study
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cataract
A Novel Congenital Cataract Category System
Congenital cataracts (CC) are the leading cause of childhood visual disabilities and treatable childhood blindness worldwide1. CC patients have a wide range of presentations of lens opacities and are generally categorized into…
- Trial name
- NCT02793869
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Sun Yat-sen University
Cataract
Longitudinal Changes in Refractive Error After Primary IOL Implantation Among Children With Congenital Cataract
The purpose of prospective cohort study is to estimate the rate of change in postoperative change after primary IOL implantation among children with congenital cataract(CC) and to explore key factors associated with the rate of…
- Trial name
- NCT04441268
- Testing
- primary IOL implantation
- Where
- China
- Volunteers
- 335 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract
Clinical Characteristics in Congenital Cataract Eyes
This study involved children with congenial cataract eyes, who underwent cataract surgeries at the Eye Hospital of Wenzhou Medical University (Hangzhou, China). All medical records were reviewed for primary diagnosis.
- Trial name
- NCT03905044
- Testing
- eyes with congenital cataracts
- Volunteers
- 239 people
- Sponsor
- yin ying zhao
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Congenital Cataract
Inflammatory Cytokines in Congenital Cataract After Lensectomy and Anterior Vitrectomy
In this prospective study , a cohort of 58 eyes with congenital cataract from Wenzhou medical university was erolled.33 eyes with congenital cataract was after lensectomy and anterior vitrectomy as post-surger group, 26 eyes…
- Trial name
- NCT04120818
- Testing
- secondary IOL implantation, primary IOL implantation
- Where
- 2 sites in China
- Volunteers
- 59 people
- Sponsor
- yin ying zhao
Cataract
Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative…
- Trial name
- NCT02581046
- Testing
- Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients, Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Cataract
The Visual Plasticity During Adversity and Prosperity in Infants With Congenital Cataracts
Phenotypic plasticity is the ability of individuals to change their phenotypic status when exposed to environmental variations. However, whether the plastic changes show differential susceptibility in adversity and prosperity is…
- Trial name
- NCT03593824
- Testing
- bilateral cataract removal surgery for dense cataract, bilateral cataract removal surgery for non-dense nuclear cataract
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract
Aphakia Versus Pseudophakia in Children Under 2 Years Undergoing Bilateral Congenital Cataract Surgery
The purpose of this study is to document the safety and efficacy of primary IOL implantation in children below 2 years of age undergoing congenital cataract surgery.
- Trial name
- NCT01297153
- Testing
- Intraocular Lens (Acrysof IOL), No IOL
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Iladevi Cataract and IOL Research Center
Macular, Congenital Cataract
Effects of 23-gauge Lensecotomy Combined With Anterior Vitrectomy on Macular in Children With Congenital Cataract
Congenital cataract is the main cause of form deprivation amblyopia in children. Current studies confirm that form deprivation amblyopia affects the macular development.
- Trial name
- NCT04077489
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- yin ying zhao
Congenital Cataract
Iridocorneal Angle and Anterior Segment Structure in Eyes of Children With Cataract
The aim of this study is to evaluate the morphology of iridocorneal angle and anterior segment structure in children with cataract, and to explore potential preoperative structural clues for postoperative glaucoma.
- Trial name
- ACA (NCT03778086)
- Testing
- gonioscopy
- Volunteers
- 100 people
- Sponsor
- Wenzhou Medical University