Clinical trials: Caries; Initial
White Spot Lesion of Tooth
Effect of Self Assembling Peptide on White Spot Lesion
During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?
- Trial name
- regeneration (NCT03930927)
- Testing
- Self Assembling peptide, remineralizing agent
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raneen Ahmed
Dental Caries, Early Caries Lesion
Effect of Ozone Therapy on Remineralization of Initial Caries Lesions in Children
Initial caries lesions can be managed using non-invasive treatment approaches that promote remineralization and prevent lesion progression.
- Trial name
- OZONE-CARIES (NCT07671651)
- Testing
- Ozone Therapy, other
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Neslihan Atmaca
Light Fluorescence Device
Clinical Effectiveness of(VistaProof)in Comparison With ICDAS-II & Histological Validation for Detecting Occlusal Caries
a diagnostic accuracy study control trial is to be held to evaluate the Clinical performance of quantitative light fluorescence based device (Vistacam Proof) in comparison with the visual examination and histological validation…
- Trial name
- NCT03940170
- Testing
- vistacam proof, ICDASII, fissurotomy
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Mohamed samy El-sayed
Caries; Initial
Efficacy of Resin Infiltration of Proximal Caries
The aim of the present study was to assess the clinical efficacy of resin infiltration of interproximal caries lesions using a novel measure method-----DIAGNOcam.
- Trial name
- RIDCBW (NCT04092296)
- Testing
- resin infiltration, remineralization
- Where
- China
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Wuhan University
Caries, Caries,Dental
Extraction of the Compromised First Permanent Molars
Compromised first permanent molars (FPM), whether diagnosed with severe molar incisor hypomineralization (MIH), irreversible pulpities, or necrosis, require frequent re-treatment consequently entering the restorative cycle, which…
- Trial name
- FPM (NCT06231823)
- Testing
- Extraction
- Where
- Egypt
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
White Spot Lesion of Tooth, Orthodontic Treatment
S-PRG Filler for Preventing White Spot Lesions During Orthodontic Treatment
White spot lesions are early areas of enamel demineralization that may develop during orthodontic treatment with fixed braces. This study aims to evaluate the effectiveness of S-PRG Barrier Coat in preventing white spot lesions…
- Conditions
- White Spot Lesion of Tooth, Orthodontic Treatment, Enamel Demineralization, Fluoride Varnishes
- Trial name
- SPRG-WSL (NCT07839780)
- Testing
- S-PRG Barrier Coat, S-PRG Barrier Coat + 5% Sodium Fluoride Varnish, 5% sodium fluoride varnish
- Where
- Malaysia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
White Spot Lesion of Tooth
Clinical Outcomes, Cost-Effectiveness and Patient Satisfaction of Two Resin Infiltration Systems for The Management of White Spot Lesions
The aim of this study is to clinically evaluate and compare the color matching of white spot lesions (WSLs) following treatment with two resin infiltration systems: ICON resin infiltration and I-Mate resin infiltration.
- Trial name
- NCT07799350
- Testing
- light cured low viscosity resin infiltration
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions
The current study aimed to evaluate the color change potential of wheat grass and white tea on post orthodontic white spot lesions (WSLs).
- Trial name
- NCT06976385
- Testing
- White tea, Wheat grass solution
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
White Spot Lesion of Tooth
Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions
this study aimed to assess the effect of the application of the low-viscosity Icon resin infiltrate on the color change of the diagnosed white spot enamel lesions (WSLs) over 3-, 6-, and 12-m follow-up periods.
- Trial name
- NCT05757440
- Testing
- Icon resin application
- Where
- Egypt
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
Dental Caries, Irreversible Pulpitis
Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis
This study evaluates the effectiveness of photobiomodulation (PBM) in conjunction with mineral trioxide aggregate (MTA) pulpotomy for treating irreversible pulpitis in immature first permanent molars.
- Trial name
- NCT06730360
- Testing
- MTA Pulpotomy without photobiomodulation, MTA Pulpotomy with Photobiomodulation (LLLT)
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Permanent Molars, Dental Caries
Hall Technique vs Conventional Crown Restoration in Permanent Molars: Split-Mouth Trial in Children
The aim of this study is to compare the clinical and radiographic success of stainless steel crowns placed using the Hall Technique versus the conventional method in the restoration of permanent first molars in children, and to…
- Conditions
- Permanent Molars, Dental Caries, Tooth Decay, Permanent First Molar Caries
- Trial name
- HTCC-SM (NCT07186673)
- Testing
- Stainless steel crown placement using Hall Technique, Stainless steel crown placement using conventional method
- Where
- 2 sites in Syria
- Volunteers
- 10 people
- Sponsor
- Latakia University
White Spot Lesion of Tooth
Efficacy of Different Agents in Treatment of Initial Caries on Smooth Surfaces in Permanent Teeth in Children
White spot lesions (WSL) are characterized by an apparently intact outer surface and a demineralized subsurface, and are considered the first clinical sign of dental caries.
- Trial name
- NCT05206539
- Testing
- Self-assembling peptide (P11-4), CPP-ACFP, Resin infiltration
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth
Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting
The goal of this clinical trial is to assess the efficacy of "Icon® resin infiltration" and "VanishTM XT varnish" in restoring the appearance of white spot lesions WSLs in healthy children affected with anterior white spot…
- Conditions
- White Spot Lesions, White Spot Lesions [Initial Caries] on Smooth Surface of Tooth, Enamel Hypomineralization
- Trial name
- RI (NCT06696105)
- Testing
- Resin infiltration, Vanish XT varnish (resin modified glass ionomer restoration)
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children
This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and…
- Trial name
- NCT07725757
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Caries Prevention
Effectiveness of Using (Vanish XT) in Prevention of Occlusal Caries: a RCT
Despite the continuous effort to prevent and treat dental caries, it continues to be one of the most common chronic diseases in both children and adults.
- Trial name
- NCT04579536
- Testing
- Light curable resin modified glass ionomer varnish, Vanish White Varnish
- Where
- Saudi Arabia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
White Spot Lesion of Tooth
Effect of Diode Laser With Dye and Remineralizing Agent on Surface Area of White Spot Lesions by Using Digital Subtraction Radiograph Techniques.
The current study was conducted to compare effect of diode laser and perio green dye with reminerlizing agent on surface area white spot lesions by using digital subtraction radiographic techniques.
- Trial name
- NCT07818655
- Testing
- remin pro
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Caries, Dental
Accuracy Of Sopro-Life Camera In Comparison With ICDAS II For Detection Of Initial Caries
This study will be conducted to assess diagnostic predictive values of a light induced fluorescence intraoral camera versus those of the visual-tactile assessment method according to modified ICDAS-II criteria in clinical
- Trial name
- NCT03586713
- Testing
- light induced fluorescence camera
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries, Dental
Atraumatic Restorative Treatment Sealants in First Permanent Molars
The aim of this bi-center study was to evaluate the retention and caries-preventive effect of Atraumatioc Restorative Treatment (ART) sealants, using two glass ionomer cement (GIC) versus non-sealant on first permanent molars of…
- Trial name
- NCT03667768
- Testing
- Glass ionomer sealant, Non-sealant (toothbrushing)
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
White Spot Lesion of Tooth
White Spot Lesions Prevention During Orthodontic Fixed Appliance Treatment: a Randomized Clinical Trial
The aim of this study is to evaluate the effectiveness of calcium fluoride nanoparticles containing orthodontic primer in preventing or decreasing the incidence WSLs over a period of 6 months in patients with fixed orthodontic…
- Trial name
- NCT04994314
- Testing
- nCaF2 primer, Control primer
- Where
- Iraq
- Volunteers
- 31 people
- Sponsor
- University of Baghdad