Clinical trials: Cardiovascular Events
STEMI
Follow up of Clinical Outcome of Deferred vs Immediate Stenting in High Thrombus Stemi Patients
To compare the effect of immediate stenting versus deferred stenting - with use of glycoproteinIIbIIIa inhibitor \& low molecular weight heparin - on the clinical outcome -3 and 6 months after stenting \& also infarct size using…
- Trial name
- NCT05793671
- Testing
- PPCI in heavy thrombus burden STEMI patients
- Volunteers
- 440 people
- Sponsor
- Assiut University
Apnea of Prematurity, Apneic Spells of Newborn Nos
Cardio-respiratory Events in Preterm Infants During Transition
Cardio-respiratory events (CRE), defined as intermittent episodes of hypoxemia and/or bradycardia, are particularly common among preterm infants.
- Conditions
- Apnea of Prematurity, Apneic Spells of Newborn Nos, Patent Ductus Arteriosus, Premature Birth
- Trial name
- NCT04123691
- Testing
- pulse oximetry monitoring
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Ischemic Attack, Transient
Cognitive and Physical Functions in Patients With Transient Ischemic Attack. A Randomized Controlled Trial of Physical Activity on Prescription up to One Year After the Event
The purpose of this study is to determine whether Physical Activation on Prescription can help patients with TIA to become more physically active.
- Trial name
- NCT01509924
- Testing
- Physical activation on Prescription
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Tiohundra AB
Peripheral Arterial Disease(PAD)
Effect of Anticoagulant and Antiplatelet Drug Intervention on Postoperative Major Adverse Events in Patients with PAD：Phase II
This study is a multicenter, prospective, observational research project. It is anticipated to enroll a total of 6,000 patients between February 1, 2025, and January 31, 2028 (with completion of one-year postoperative follow-up…
- Trial name
- NCT06850207
- Volunteers
- 6,000 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Venous Thromboembolism, Pediatrics
Using a Real-Time Risk Prediction Model to Predict Pediatric Venous Thromboembolism (VTE) Events
The study will evaluate the effectiveness of a novel, real-time risk prediction model for identifying pediatric patients at risk for developing in-hospital blood clots (or venous thromboembolism [VTE]) based on data easily…
- Conditions
- Venous Thromboembolism, Pediatrics, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT04574895
- Testing
- Hematology Review
- Where
- United States
- Volunteers
- 17,427 people
- Sponsor
- Vanderbilt University Medical Center
Coronary Artery Disease, End Stage Renal Disease
Prospective Study of End Stage Renal Disease Patients With Coronary Artery Disease Treated by Oral Nicorandil
Nicorandil is potentially effective to prevent cardiovascular events in patients with coronary artery disease (CAD) receiving hemodialysis.
- Trial name
- NCT01475123
- Testing
- Nicorandil
- Where
- Japan
- Volunteers
- 268 people
- Sponsor
- Kumamoto University
Retinal Detachment, Achilles Tendon
A Study of Fluoroquinolones Exposure and Collagen-Related Serious Adverse Events
The purpose of this study is to evaluate whether there is an increased risk of achilles tendon rupture (ATR), retinal detachment (RD) or aortic aneurysm and dissection (AAD) following exposure to fluoroquinolone (FQ) or other…
- Conditions
- Retinal Detachment, Achilles Tendon, Aneurysm, Dissecting
- Trial name
- NCT03479736
- Testing
- Oral Fluoroquinolones (FQ), Other Antibiotics, Febrile Illness Not Treated with Antibiotics Will be Analyzed as an Exposure
- Where
- United States
- Volunteers
- 117,911 people
- Sponsor
- Janssen Research & Development, LLC
Hypertension
Post Marketing Surveillance (PMS) Study to Assess Safety and Efficacy of Micardis in Patients With Essential Hypertension
The objective of this PMS study was to monitor and assess the safety of Micardis tablets in patients with hypertension over a period of 6 years
- Trial name
- NCT02245464
- Testing
- Telmisartan
- Volunteers
- 13,066 people
- Sponsor
- Boehringer Ingelheim
Ischemic Cardiovascular Disease
Multicenter Randomised Prospective Study for External Support Mesh VEST of Venous Coronary Grafts on the Right Territory
Multicentre randomised prospective study aimed at verifying medium-term patency of venous grafts on the right coronary artery territory, by clinical and/or instrumental follow-up with particular attention to clinically driven…
- Trial name
- RiVEST (NCT06877195)
- Testing
- CABG
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Cardiochirurgia E.H.
Myocardial Infarction
Pattern of Repeat Cardiovascular Events During Follow-up After First Diagnosed Event-MI
Recurrent myocardial infarctions (reinfarctions) can be due to recurrence at the original treatment site, the presence of untreated lesions elsewhere, or in progressive lesions.
- Trial name
- PRECLUDE-MI (NCT03099395)
- Volunteers
- 100,000 people
- Sponsor
- Uppsala University
Asthma in Children, Atrial Fibrillation
Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches
The MEDEA project is envisioned to provide the field-based evidence for the adoption of a strategic plan for mitigating the health effects of desert dust storm (DDS) events in South-Eastern Europe.
- Trial name
- MEDEA (NCT03503812)
- Testing
- Intervention (1) for outdoor exposure reduction - Asthma in Children, Intervention (2) for outdoor and indoor exposure reduction - Asthma in Children, Intervention (1) for outdoor exposure reduction - Atrial Fibrillation
- Where
- 3 sites in Cyprus, Greece and 1 more
- Volunteers
- 310 people
- Sponsor
- University of Cyprus
Unexpected Hospital Mortality, Death, Sudden, Cardiac
Prevention of Serious Adverse Events in Acute Care Hospitals by Afferent Limb and Response Method Intervention - the ALARM Intervention Study.
1. Summary Growing evidence suggests that a significant proportion of in-hospital patient deaths occur after serious adverse events (SAE's).
- Conditions
- Unexpected Hospital Mortality, Death, Sudden, Cardiac, Unplanned Intensive Care Unit Admission
- Trial name
- ALARM (NCT01949025)
- Testing
- ALARM intervention
- Where
- Belgium
- Volunteers
- 69,656 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Vomiting, Cardiovascular Event
CV Events in Emetogenic Chemotherapy
Describe cardiovascular events in a cancer population receiving highly emetogenic chemotherapy (HEC) or moderately emetogenic chemotherapy (MEC).
- Conditions
- Vomiting, Cardiovascular Event, Arterial Thromboembolic Event
- Trial name
- NCT01366599
- Testing
- HEC or MEC
- Volunteers
- 12,058 people
- Sponsor
- GlaxoSmithKline
Transient Ischemic Attack, Non-disabling Stroke
Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT
The objective of the Program of Rehabilitative Exercise and Education to avert Vascular Events after Non-disabling stroke and Transient ischemic attack (PREVENT) Trial is to determine whether the timely delivery of secondary…
- Trial name
- PREVENT (NCT00885456)
- Testing
- PREVENT program, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 187 people
- Sponsor
- Marilyn MacKay-Lyons
Myocardial Injury After Noncardiac Surgery (MINS)
SecondarY Prevention and maNagement of Myocardial Injury aftER Noncardiac surGerY (SYNERGY) Pilot Trial
Cardiac complications, particularly myocardial injury after noncardiac surgery (MINS), significantly contribute to 30-day mortality, affecting about 1 in 10 patients after noncardiac surgery.
- Trial name
- NCT06768034
- Testing
- Intervention Group
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Venous Thromboembolism
Comparative Study of Prophylactic Agent for Venous Thromboembolism After Total Knee Arthroplasty
The purpose of this study is to compare the efficacy of two prophylactic agent(aspirin 300mg/day and rivaroxaban 10mg/day) for venous thromboembolism after total knee arthroplasty.
- Trial name
- NCT02271399
- Testing
- acetylsalicylic acid, rivaroxaban
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Hanyang University Seoul Hospital
Sudden Cardiac Death, Acute Coronary Event
Finnish Genetic Study for Arrhythmic Events
Finnish Genetic Study for Arrhythmic Events (FinGesture is a prospective case-control study assessing the characteristics and genetic background of consecutive series of autopsy verified out-of-hospital victims of SCD vs.
- Trial name
- FinGesture (NCT02075866)
- Where
- Finland
- Volunteers
- 8,000 people
- Sponsor
- University of Oulu
Atrial Fibrillation
Warfarin - How Good Are we at Maintaining Target Range ?
Patients with atrial fibrillation are often anticoagulated with Warfarin. Warfarin has a narrow therapeutic window requiring frequent monitoring.
- Trial name
- NCT01081327
- Where
- United Kingdom
- Volunteers
- 5,000 people
- Sponsor
- University of Dundee
Cardiovascular Event, Coronary Artery Bypass Graft
Glycosylated Hemoglobin and Risk of Perioperative Major Cardiovascular Events in Diabetic Patients Undergoing Coronary Bypass Revascularization (HbA1c)
Glycosylated Hemoglobin (HbA1c) is considered as one of the best markers to assess the glycaemia treatment over a period of 3 to 4 months, and is considered as predictive marker for perioperative mortality and morbidity.
- Conditions
- Cardiovascular Event, Coronary Artery Bypass Graft, Diabetes Mellitus
- Trial name
- NCT03590223
- Testing
- Coronary Bypass Revascularization
- Where
- Switzerland
- Volunteers
- 589 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiac Event
Pharmacokinetics of Post Operative Cefuroxime in Infants Undergoing Cardiac Surgery
To evaluate plasma concentrations of Cefuroxime in this patient population To determine if certain pathophysiological and/or iatrogenic conditions alter the pharmacokinetics in this patient group.
- Trial name
- PHOXEY (NCT02850250)
- Testing
- Cefuroxime
- Sponsor
- Alder Hey Children's NHS Foundation Trust