Clinical trials: CVD - Cardiovascular Disease
Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD)
Relationship Between Insulin Dose and Complications in Type 1 Diabetes
The goal of this observational study is to better understand how the amount of insulin people with type 1 diabetes are using relates to blood glucose control and the risk of complications.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD), Severe Albuminuria, Estimated Glomerular Filtration Rate (eGFR)
- Trial name
- iDose-EDC (NCT07911033)
- Testing
- Routine/prescribed exogenous insulin dose
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rachel Miller
Obesity, Type 2 Diabetes (T2D)
A Retrospective Real-World Cohort Study
The primary objectives are to determine the prevalence and overlap of major cardiometabolic diseases, identify multimorbidity clusters, and characterize demographic, clinical, laboratory, and treatment patterns across the cohort…
- Conditions
- Obesity, Type 2 Diabetes (T2D), Prediabetes, Cardiovascular Disease (CVD)
- Trial name
- SCALA-TK-CM (NCT07781371)
- Testing
- No treatment given
- Where
- Denmark
- Volunteers
- 100,000 people
- Sponsor
- Novo Nordisk A/S
Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk
Cardiovascular Health and Nursing Interventions in 6th Grade Middle School Children
Interventions that can improve cardiovascular health behaviors in children are of critical importance for reducing the burden of cardiovascular disease in the future.
- Conditions
- Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk, Health Behavior, School Health Services
- Trial name
- NCT06812156
- Testing
- Cardiovascular Health Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Cardiovascular Diseases (CVD), Cerebro Vascular Disease
Identifying Risk Factors and Predicting Future Health Outcomes for Korean Patients With Heart and Blood Vessel Diseases: A Long-term Follow-up Study
This study aims to establish a comprehensive, long-term clinical registry infrastructure for heart and brain vascular diseases (cardiovascular diseases and stroke) at Samsung Medical Center.
- Trial name
- NCT07393412
- Testing
- Standard Medical Therapy, Revascularization Procedures, Lifestyle Modification
- Where
- South Korea
- Volunteers
- 800,000 people
- Sponsor
- Samsung Medical Center
Cardiovascular Diseases (CVD)
Heart Institute BioRepository (HIBR) for Pediatric Heart Disease
The purpose of this protocol is to redefine the Heart Institute BioRepository (HIBR) to facilitate Investigator-initiated and programmatic basic, translational, clinical and outcomes research.
- Trial name
- HIBR (NCT07478354)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
Towards Personalized Nutrition With SCAPIS2-HOME
The Swedish CardioPulmonary bioImage Study (SCAPIS) is a nationwide, open-access, population-based cohort in Sweden designed to study cardiovascular disease and chronic obstructive pulmonary disease.
- Trial name
- NCT06992921
- Testing
- Dietary intervention
- Where
- 2 sites in Sweden
- Volunteers
- 1,641 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Wearable Electronic Devices, Polygenic Risk Score
DELphi Procedure for Developing Recommendations for the Implementation of Wearable Devices and Polygenic Risk Scores
DEL-DIP is a prospective observational study employing a Delphi methodology (at least two online rounds) to elicit and consolidate the views of an expert panel within the INNOPREV project.
- Conditions
- Wearable Electronic Devices, Polygenic Risk Score, CVD - Cardiovascular Disease, Primary Prevention
- Trial name
- DEL-DIP (NCT07358481)
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gender Incongruence, Cardiovascular Disease (CVD) Risk Factors
Cardiomodulatory Effects of Gender-Affirming Hormone Therapy
Gender-affirming hormone therapy is today a well-established treatment for individuals experiencing gender-incongruence. However, little is known about the long-term effects of gender-affirming hormone therapy on the…
- Trial name
- CARMEN (NCT07128771)
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Cardiovascular Diseases (CVD)
Swiss Secondary Prevention and Rehabilitation Registry
The SwissPR study is to continuously monitor patient characteristics and short- and long-term benchmark quality measures and outcomes of patients participating in a 12-week ambulatory CR program.
- Trial name
- SwissPR (NCT05500859)
- Testing
- Data collection at Baseline, 3 months after baseline (BL), 1-year follow-up, Telephone follow-up and questionnaire 3 years and 5 years after BL
- Where
- Switzerland
- Volunteers
- 4,000 people
- Sponsor
- University Hospital, Basel, Switzerland
CVD, Cardiovascular Diseases
Hoosier Sport: Refining and Implementing a Sustainable Campus-Community Partnership in Rural Indiana
Hoosier Sport is a sport-based youth development program that uses the power of sport to teach children and adolescents sport and leadership skills while promoting health education.
- Trial name
- NCT06602596
- Testing
- Hoosier Sport
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Indiana University
Depression and CVD
Study on the Mechanism of Multi-group Analysis of the Influence of Depression on Common Cardiovascular Diseases
Cardiovascular disease is the main cause of death in the world, accounting for 32% of all deaths. In 2019, the number of people suffering from cardiovascular diseases in the world was about 523 million, of which about 18.6…
- Trial name
- NCT06975592
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Diabetes Mellitus, Cardiovascular Diseases (CVD)
Da Qing Offspring Study
This is an observational study tracking families and offspring of three cohorts from the 1986 Da Qing study: newly diagnosed diabetes, impaired glucose tolerance, and normoglycemia groups.
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases (CVD), Offspring, Adult, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- NCT06958640
- Testing
- Lifestyle interventions
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Cardiovascular Disease (CVD), Hypertension
Veteran Peer Coaches Optimizing and Advancing Cardiac Health
The purpose of this study is to test if having a Veteran peer health coach will improve blood pressure control among Veterans with high blood pressure and at least one other Cardiovascular disease (CVD) risk factor.
- Conditions
- Cardiovascular Disease (CVD), Hypertension, Hyperlipemia, Obesity
- Trial name
- Vet-COACH (NCT02697422)
- Testing
- Community-based peer health coach intervention
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- VA Office of Research and Development
Chronic Venous Disease (CVD), Vein Compliance, Venous Clinical Severity Score (VCSS)
Correlation Between Popliteal Vein Compliance and Venous Clinical Severity Score
When the liquid flow increases, the luminal caliber's stretching amplitude decreases, leading to a higher hydraulic pressure according to Poiseuille's law.
- Trial name
- NCT06175481
- Testing
- Popliteal Vein Compliance
- Where
- China
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Hyperkalemia Elevated Plasma K+ Cardiovascular Disease (CVD)
Retrospective Study to Describe Prevalence of Hyperkalemia in Russian Population Based on Large Laboratory Network (HEKATE)
This is a cross-sectional retrospective study of laboratory records of patients who take electrolytes blood tests containing the data of the serum potassium level.
- Trial name
- NCT03657875
- Where
- Russia
- Volunteers
- 53,940 people
- Sponsor
- AstraZeneca
Postpartum CVD Risk in Women With Previous Preeclampsia.
Preeclampsia and Circulating Biomarkers
In order to assess circulating biomarkers of cardiovascular risk, we will conduct a 10-year follow-up study comparing 32 exposed (women with a history of pregnancy complicated by preeclampsia) and 32 unexposed (women with a…
- Trial name
- NCT02136667
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- University of Aarhus
Cardiovascular Disease (CVD) Risk Factors
Feedback of Treatment Intensification Data to Reduce Cardiovascular Disease Risk (FIT)
The primary research question of this study is to determine whether measuring, reporting and feeding back information to primary care teams on the need for treatment intensification in patients at high risk for cardiovascular…
- Trial name
- FIT (NCT00517686)
- Testing
- Information feedback intervention
- Where
- United States
- Volunteers
- 16,584 people
- Sponsor
- Kaiser Permanente