Clinical trials: Breast Cancer Surgery
Intraabdominal Hypertension, Breast Neoplasms
DIEP Flap Surgery and Intraabdominal Pressure
Aim: The primary aim of this study is to test if closure of the abdominal donor site increases the Intraabdominal Pressure (IAP) in women undergoing secondary Deep Inferior epigastric perforator (DIEP) flap breast reconstruction.
- Trial name
- NCT05764577
- Testing
- DIEP flap surgery
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Aalborg University Hospital
Breast Cancer
Combination Chemotherapy Following Surgery in Treating Women With Early Stage Breast Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known which combination chemotherapy regimen is more effective following surgery for breast…
- Trial name
- NCT00003012
- Testing
- CMF regimen, cyclophosphamide, epirubicin hydrochloride
- Where
- 10 sites in United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Scottish Cancer Therapy Network
Breast Cancer
Axillary Lymph Node Preservation Surgery in Reducing Lymphedema in Patients With Breast Cancer
This pilot phase I and randomized phase II trial studies the best way to perform axillary lymph node preservation surgery and to see how well it works in preventing lymphedema in patients with breast cancer.
- Trial name
- NCT00932035
- Testing
- axillary lymph node dissection, isosulfan blue based lymphatic mapping, quality-of-life assessment
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- City of Hope Medical Center
Breast Cancer Surgery
Effect of Intravenous S-ketamine on Opioid Consumption
Female patients with an American Society of Anesthesia (ASA) physical status I-II, scheduled for elective breast cancer surgery will be included in the study.
- Trial name
- NCT05060068
- Testing
- S-ketamine (low dose), S-ketamine (high dose)
- Where
- China
- Volunteers
- 345 people
- Sponsor
- The Second Hospital of Anhui Medical University
Carcinoma Breast Stage IV
Role of Surgery for the Primary in Patients With Breast Cancer Stage IV.
The purpose of this study is to determine benefits of surgery for the primary in patients with breast cancer stage IV in randomized controlled study.
- Trial name
- NCT01906112
- Testing
- Surgery for primary breast tumor.
- Where
- 9 sites in Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Cancer Institute, Thailand
Breast Disease, Breast Neoplasms
Pattern of Clinical Presentation of Different Breast Disease in Surgical Opd at BPKIHS
Research Title PATTERN OF CLINICAL PRESENTATION OF DIFFERENT BREAST DISEASE IN SURGICAL OPD AT BPKIHS Rationale: The Study will help us to know about pattern of presentation of different breast diseases Aims and Objectives: 1.
- Conditions
- Breast Disease, Breast Neoplasms, Breast Pain, Breast Fibroadenoma
- Trial name
- NCT06026176
- Where
- Nepal
- Volunteers
- 1,023 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Breast Cancer, Chemotherapy Effect
Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer
Introduction: Neoadjuvant chemotherapy (NACT) has been the standard therapy for treating patients with locally advanced breast cancer (LABC). Doxorubicin-based regimen showed a clinical response for 70-80%.
- Trial name
- NCT04418089
- Testing
- Simvastatin 40mg
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Breast Cancer
A Prospective Comparative Study Between Oncoplastic Breast Surgery and Standard Wide Local Excision
The aim of this study is to asses the oncological safety of oncoplastic breast surgery, and its impact on patient satisfaction.
- Trial name
- NCT02923635
- Testing
- Standard wide local excision., oncoplastic breast surgery.
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Non Metastatic Breast Cancer
The Impact of Oncoplastic Breast Surgery on the Oncological Safety and Patient Satisfaction
The aim of this study is to asses the oncological safety of oncoplastic breast surgery, its impact on patient satisfaction and is it worthy for general breast surgeon to learn different oncoplastic techniques.
- Trial name
- NCT02901223
- Testing
- Standard quadrantectomy, oncoplastic breast surgery
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Breast Cancer
Anti-tumour Effects & Tolerability of Faslodex Alone or in Combination With Arimidex in Post Menopausal Women Prior to Surgery for Primary Breast Cancer
To compare the anti-tumour effects as measured by changes in various biomarkers, of a combination of Faslodex and Arimidex with Faslodex alone and Arimidex alone in postmenopausal women patients with primary breast cancer who are…
- Trial name
- NCT00259090
- Testing
- Fulvestrant, Anastrazole
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Breast Cancer
Exemestane, Letrozole, or Anastrozole in Treating Postmenopausal Women Who Are Undergoing Surgery for Stage II or Stage III Breast Cancer
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using exemestane, letrozole, or anastrozole, may fight breast cancer by lowering the amount of estrogen the body makes.
- Trial name
- NCT00265759
- Testing
- anastrozole, exemestane, letrozole
- Where
- 3 sites in United States
- Volunteers
- 622 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Breast Cancer
Physiotherapy Program for Breast Cancer Women Following Surgery: A Pilot Clinical Trial
pilot study on physical therapy in women with breast cancer immediately following surgery
- Trial name
- NCT04894565
- Testing
- rehabilitation
- Where
- Saudi Arabia
- Volunteers
- 23 people
- Sponsor
- King Fahad Medical City
Breast Cancer
Chemotherapy in Treating Women With Breast Cancer That Can Be Surgically Removed
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if chemotherapy given before surgery is more effective with or without docetaxel given…
- Trial name
- NCT00002707
- Testing
- Cyclophosphamide, Docetaxel, Doxorubicin
- Where
- 145 sites in United States, Canada
- Volunteers
- 2,411 people
- Sponsor
- NSABP Foundation Inc
Breast Cancer
Trial Comparing Perioperative Care for Breast Cancer Patients at a Patient Hotel vs a General Surgical Ward
To explore the possible benefit of a patient hotel, a study was undertaken to test the hypothesis that perioperative care at a patient hotel would be valued better than care in a general ward.
- Trial name
- NCT02403973
- Testing
- IN2005E
- Volunteers
- 151 people
- Sponsor
- Danderyd Hospital
Breast Cancer Surgery, Benign Breast Tumors
Analysis of Recurrence of Intraductal Papilloma Treated With Vacuum-assisted Rotary Excision
To study the postoperative recurrence of intraductal papillomas (IDP) treated with ultrasound-guided vacuum-assisted excision (VAE), and to investigate the effect of different lesion characteristics on recurrence.
- Trial name
- IDP (NCT06970561)
- Testing
- enlarged resection
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Wuhan Children's Hospital
Breast Cancer
Effect of Fluvastatin on Biomarkers in Women Who Are Undergoing Surgery for Ductal Carcinoma In Situ or Stage I Breast Cancer
RATIONALE: Collecting samples of blood and tissue from patients with cancer to study in the laboratory may help doctors learn how fluvastatin effects biomarkers related to breast cancer.
- Trial name
- NCT00416403
- Testing
- fluvastatin sodium, Breast Cancer Surgery Only - Arm III
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Francisco
Breast Cancer
Collecting Tissue Samples for Future Research From Women Undergoing Surgery for Breast Cancer
RATIONALE: Collecting and storing samples of tumor tissue from patients with breast cancer to study in the laboratory may help doctors learn more about cancer.
- Trial name
- NCT00898131
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Northwestern University
Breast Cancer
How Breast Conservative Surgery (BCS) Affects Women's Daily Activities On Post-Operation 2 Days?
we revise 8 disability items from SPADI into Chinese to develop a simple self-completion questionnaire for the assessment of restriction in daily activities resulting from breast conservative surgery.
- Trial name
- NCT00265213
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Breast Cancer, Modified Radical Mastectomy
Use of Harmonic in Breast Surgery
To compare harmonic scalpel with electrocautery for outcomes i.e. estimated blood loss (EBL), operating time, drain Volume and drain Days, seroma formation, surgical site infection and postoperative pain in adult females…
- Trial name
- HMRM (NCT01587248)
- Testing
- Harmonic, electrocautery
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Aga Khan University
Breast Cancer
Studying Cells Collected Through Ductal Lavage in Women Undergoing Surgery for Ductal Carcinoma In Situ or Other Breast Cancer
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00896857
- Testing
- RNA analysis, polymerase chain reaction, protein expression analysis
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences