Clinical trials: Borderline Symptoms
Self Harm, Borderline Personality Disorder
Predictors of Clinical Course and Treatment Response in DBT Programmes
The project is a collaboration between The National Centre for Suicide Research and Prevention (NSSF) and clinical units with Dialectical Behaviour Therapy (DBT) programmes.
- Trial name
- NCT04318899
- Testing
- Dialectical Behaviour Therapy adapted for adolescents (DBT-A), Dialectical Behaviour Therapy - Standard version (DBT)
- Where
- 5 sites in Norway
- Volunteers
- 250 people
- Sponsor
- Oslo University Hospital
Acute Undifferentiated Leukemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative
Collecting and Storing Malignant, Borderline Malignant Neoplasms, and Related Samples From Young Patients With Cancer
This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer.
- Conditions
- Acute Undifferentiated Leukemia, Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, Childhood Acute Lymphoblastic Leukemia, Childhood Acute Myeloid Leukemia
- Trial name
- NCT00898079
- Testing
- Cytology Specimen Collection Procedure
- Where
- 192 sites in United States, Australia and 4 more
- Volunteers
- 2,545 people
- Sponsor
- Children's Oncology Group
Self-harm, Personality Disorder, Borderline
Self-harm Behaviour Among the Most At-risk Adolescents
In the proposed study, three objectives will be pursued: 1. To develop a method to identify more effectively the acute and long-term risk of adolescents with the most threatening self-harm behaviours. 2.
- Conditions
- Self-harm, Personality Disorder, Borderline, Epigenetic Disorder, Non-Suicidal Self Injury
- Trial name
- SH-MARA (NCT05765864)
- Testing
- Enrollment questionnaire, General questionnaire1, General questionnaire2, General questionnaire3, Columbia Suicide Severity Rating Scale (CSSRS), The Brief Non-Suicidal Self-Injury Assessment Tool (B-NSSI-AT)
- Where
- 2 sites in Slovenia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana, Faculty of Medicine
Borderline Intellectual Functioning (BIF), Intellectual Disability
Co-design of an AI Rehabilitation Program for Children With Borderline Intellectual Disorder
Co-design of an AI Rehabilitation Program for Children With Borderline Intellectual Disorder
- Trial name
- NCT07625592
- Testing
- Tablet-Based AI Cognitive and Language Rehabilitation Program
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder
Emotional and Non-emotional Regulation in Patients With Emotional Instability and ADHD
The purpose of this study is to investigate how emotional and non-emotional regulation processes differ in EIP patients (with different levels of ADHD symptoms/ADHD-comorbidity) compared to controls.
- Conditions
- Emotional Instability Personality Disorder (Borderline Personality Disorder), Attention Deficit Hyperactivity Disorder, Healthy Controls
- Trial name
- NCT02797873
- Testing
- fMRI - Stroop task, fMRI - MID task, Stop Signal Task
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Borderline Symptoms, Borderline Personality Disorder
The Effectiveness of Group Schema Therapy in the Treatment of Borderline Symptoms in Adolescents
The goal of this randomized and controlled trial is to assess the effectiveness of group schema therapy in the treatment of adolescents with borderline symptoms.
- Trial name
- NCT06606002
- Testing
- Group schema therapy, Treatment as Usual (TAU)
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Breast Cancer, Leukemia
Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Breast Cancer, Leukemia, Lymphoma, Neuroblastoma
- Trial name
- NCT00003425
- Testing
- filgrastim, amifostine trihydrate, cyclophosphamide
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Kentucky
Borderline Personality Disorder, Eating Disorders
Chrysalis Day Program Body Mass Index Study
This is a study to determine if the approach taken to treat patients in the Chrysalis Day Hospital Program will favourably effect their health status as assessed by Body Mass Index (BMI)
- Trial name
- NCT00202215
- Testing
- Chrysalis Day Program
- Where
- Canada
- Volunteers
- 106 people
- Sponsor
- Queen's University
Cluster B Personality Disorder (Diagnosis), Borderline Personality Disorder
Comparing Mentalization-based Treatment And A Dialectical Behavior Therapy-inspired Treatment On The Utilization Of Services And The Dropout Rate In A Clinical Adult Population With A Cluster B Personality Disorder
Cluster B personality disorders (borderline, narcissistic, antisocial and/or histrionic) are an important clinical consideration because of their high prevalence and associated morbidity.
- Trial name
- NCT05014217
- Testing
- Mentalization-based Treatment, Dialectical Behavior Therapy-inspired Treatment
- Volunteers
- 403 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Cancer
External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Indinavir and ritonavir may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
- Trial name
- NCT00637637
- Testing
- indinavir sulfate, ritonavir, radiation therapy
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people
- Sponsor
- Oncology Institute of Southern Switzerland
Personality Disorder, Borderline
Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Borderline personality disorder (BPD) is the most prevalent personality disorder in young community population whose most severe complication is suicide.
- Trial name
- NCT03011190
- Testing
- Emotional regulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Silvia Elisa Hurtado Santiago
Borderline Personality Disorder in Adolescence
Dialectical Behavior Therapy for Adolescents at Rutgers University
This project expands our existing psychological services clinic (the Dialectical Behavior Therapy Clinic at Rutgers University; DBT-RU) to include an adolescent treatment arm.
- Trial name
- NCT03861858
- Testing
- DBT-A
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Rutgers, The State University of New Jersey
Deliberate Self Harm
Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents
Deliberate Self-Harm (DSH) among adolescents is a serious behavioral problem associated with significant injury, impaired functioning, reduced quality of life, and high rates of psychiatric hospitalizations.
- Trial name
- NCT01111734
- Testing
- N-Acetylcysteine, fMRI
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Self-Harm, Deliberate, Suicidal Behavior
Intensive Dialectical Behavior Therapy for Self-Harm and Suicidal Behavior in Youth: A Pilot Study
The prevalence of self-harm and suicidal behavior among adolescents has increased dramatically over the past two decades-a fourfold rise that represents both a severe personal burden and a substantial public health challenge.
- Conditions
- Self-Harm, Deliberate, Suicidal Behavior, Borderline Personality Disorder (BPD)
- Trial name
- NCT07450105
- Testing
- Intensive Dialectical Behavior Therapy
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Haukeland University Hospital
Common Bile Duct Stone
Management of Borderline Common Bile Duct Stone
Evaluation of the best line of treatment of borderline CBD stones associated with gallbladder stones whether by conservative treatment or endoscopic stone extraction as regard complete clearance rate of the CBD stones followed by…
- Trial name
- CBDS (NCT02460523)
- Testing
- conservative, ERCP
- Volunteers
- 35 people
- Sponsor
- Mansoura University
Dyslexia, Developmental, Developmental Language Disorder
Intervention Effectiveness Study of BEtter AT LEarning (BEATLE)- Digital Neuropsychological Rehabilitation Program
The purpose of this study is to evaluate the effectiveness of BEATLE with clinical samples of patients diagnosed with Developmental Language Disorder (DLD), Dyslexia, and Mixed Specific Developmental Disorder.
- Conditions
- Dyslexia, Developmental, Developmental Language Disorder, Specific Learning Disorder, Borderline Intellectual Functioning
- Trial name
- BEATLE (NCT06713863)
- Testing
- BEtter AT LEarning (BEATLE)- Digital Care Pathway
- Where
- 2 sites in Finland
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Deliberate Self Harm, Borderline Personality Disorder
Adapted Dialectical Behaviour Therapy for Adolescents With Deliberate Self-Harm: A Pre-post Observational Study
The investigators conducted a pre-post naturalistic study regarding changes observed associated with a 15-week course of an adapted form of dialectical behaviour therapy for adolescents.
- Trial name
- NCT02988037
- Testing
- A-DBT-A
- Volunteers
- 33 people
- Sponsor
- University of Ottawa
Self Injurious Behavior Without Suicidal Intent, Self-Injurious Behavior
Genetics of Self-injurious Behaviour
Nonsuicidal Self-Injury (NSSI) is being increasingly regarded as a separate psychiatric disorder. Since the latest Diagnostic and Statistical Manual of Mental Disorders - DSM-5 from 2013 defined NSSI as a separate diagnosis under…
- Trial name
- NCT05563324
- Testing
- DNA extraction and genotyping of candidate genetic polymorphisms, self-assessment questionnaires
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Maribor
Borderline Personality Disorder, Suicide and Self-harm
Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT04779099
- Testing
- Brief 4-session intervention for borderline personality disorder, Treatment as usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health