Clinical trials: Binocular Visual Function
Acquired Esotropia
Botox Instead of Strabismus Surgery (BISS)
The purpose of the study is to evaluate if strabismus can be successfully treated requiring less surgical interventions with a Botox-based treatment regimen compared to a purely surgery based treatment regimen.
- Trial name
- BISS (NCT03459092)
- Testing
- Botulinum toxin type A, Strabismus surgery
- Where
- 8 sites in France, Switzerland
- Volunteers
- 63 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Convergence Insufficiency, Binocular Vision Disorder
Convergence Insufficiency Treatment Trial (CITT)
The purposes of the CITT are: To determine whether Home-based Pencil Push-up therapy, Home-based Pencil Push-ups with Computer Vision Therapy/Orthoptics or Office-based VT/Orthoptics more effective than placebo treatment, and…
- Trial name
- NCT00338611
- Testing
- Home-based Pencil Push-Up Therapy, Home-based Pencil Push-ups with Computer Vision Therapy/Orthoptics, Office-based Vision Therapy/Orthoptics
- Where
- 9 sites in United States
- Volunteers
- 221 people
- Sponsor
- National Eye Institute (NEI)
Concussion; Syndrome
Correlation Between Changes in Measures of the Visual System and Changes in Concussion-associated Symptoms
Sports-related concussion affect 1.6 to 3.8 million people each year in the United States. Despite increased media attention and awareness campaigns, the exact number is difficult to determine due to underreporting by athletes.
- Trial name
- NCT03259178
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- McGill University
Amblyopia
Proof of Concept Study of Binocular Videogames Versus Patching for Amblyopia
The purpose of this PoC study was to evaluate the potential therapeutic efficacy of binocular video games played on a tablet and to compare the efficacy of binocular video games versus patching in amblyopic patients 4 to 7 years…
- Trial name
- NCT04784390
- Testing
- Binocular video games, Patching of the sound eye
- Where
- 8 sites in United States, Australia and 1 more
- Volunteers
- 27 people
- Sponsor
- Novartis Pharmaceuticals
Vision Disorders, Strabismus
Vision in Children Born to Opioid-dependent Methadone-maintained Mothers
The investigators will re-investigate 150 children studied extensively in the past. 100 of these children were born to mothers prescribed methadone during their pregnancy because of opiate dependency, and 50 were comparison…
- Conditions
- Vision Disorders, Strabismus, Nystagmus, Binocular Vision Disorder
- Trial name
- VINCH (NCT03603301)
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- NHS Greater Glasgow and Clyde
Amblyopia
Treatment for Amblyopia Under Binocular Conditions Versus the Standard of Care, Monocular Deprivation Treatment
Screening A child is considered for the study after undergoing a standard of care and study specific eye examinations (by a study investigator as part of standard of care) that identifies amblyopia appearing to meet the…
- Trial name
- NCT05185076
- Testing
- CureSight
- Where
- 2 sites in Israel
- Volunteers
- 114 people
- Sponsor
- NovaSight
Amblyopia
Binocular iPad Sub-Study
1. To determine whether a binocular iPad game app is effective in improving visual acuity and reducing interocular suppression in amblyopic children 2.
- Trial name
- NCT02365090
- Testing
- patching, binocular games
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Retina Foundation of the Southwest
Amblyopia
Eye-tracking Based Amblyopia Training
An Eye-Tracking-Based Binocular Amblyopia Technology Improves Both Visual Acuity and Binocularity Screening A child is considered for the study after undergoing a standard of care and study-specific eye examinations (by a study…
- Trial name
- NCT05078099
- Testing
- CureSight
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- NovaSight
Strabismus
Basic Intermittent Exotropia and Risk Factors for Postoperative Overcorrection and Under Correction
To evaluate preoperative risk factors for overcorrection and undercorrection following surgery for basic intermittent exotropia such as axial length of the globe, refractive error, age and sex
- Trial name
- NCT03153423
- Testing
- Strabismus surgery
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Minia University
Convergence Insufficiency
The Effectiveness of Visual Training in Convergence Insufficiency Patients
Convergence insufficiency (CI) is one of the most common binocular vision disorders. The prevalence of CI ranges from 3% to 6% in school-aged children.
- Trial name
- NCT05603962
- Testing
- Visual training
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Taiwan University Hospital
Amblyopia, Anisometropia
Dichoptic Virtual Reality Therapy for Amblyopia in Adults
This was a randomized, masked, controlled study of the effect of a virtual reality, binocular, 3-dimensional video game on visual acuity and stereopsis in adult patients with amblyopia.
- Conditions
- Amblyopia, Anisometropia, Strabismus
- Trial name
- NCT02246556
- Testing
- Dichoptic therapy, Patching therapy, Dioptic (non-dichoptic) therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Francisco
Exotropia, Exophoria
A-eyedrops on Ocular Alignment and Binocular Vision
Atropine is a non-selective muscarinic acetylcholine (M) receptor antagonist that paralyzes the ciliary muscle, dilates the pupil, and reduces the power of accommodation.
- Conditions
- Exotropia, Exophoria, Myopia
- Trial name
- NCT05379855
- Testing
- 0.01% atropine eye drops, 0.05% atropine eye drops
- Where
- China
- Volunteers
- 339 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Amblyopia, Strabismus
The Use of Interactive Binocular Treatment (I-BiT) for the Management of Anisometropic, Strabismic and Mixed Amblyopia in Children Aged 3.5 - 12 Years
Around one child in fifty has a lazy eye (termed amblyopia) where the eye is structurally normal but the vision fails to develop correctly.
- Trial name
- I-BiT Plus (NCT02810847)
- Testing
- I-Bit plus
- Volunteers
- 182 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Amblyopia, Binocular Vision Disorder
A Patch Free Treatment for Young Children With Amblyopia
The purpose of this study is to test whether a binocular treatment can improve vision and motor function in young children with amblyopia.
- Trial name
- NCT04086524
- Testing
- Binocular cartoon treatment at home, Patching, Binocular cartoon treatment in office
- Where
- 2 sites in United States, Australia
- Volunteers
- 34 people
- Sponsor
- University of Waterloo
Myopia
Binocular Peripheral Myopic Defocus Using a Clinical Prototype Device
Kubota Vision Inc. has developed a spectacle-like prototype device which is designed to be used as a light-based therapy to reduce myopia progression.
- Trial name
- NCT05425108
- Testing
- Binocular CP1
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Kubota Vision Inc.
Amblyopia
I-BiT - Evaluation of a Novel Binocular Treatment System (I-BiTTM) in Children With Amblyopia
The study aims to determine whether 30 minutes of treatment playing an interactive computer game weekly for 6 weeks, improves visual acuity.
- Trial name
- I-BiT (NCT01702727)
- Testing
- I-BiTTM game, Non-I-BiTTM game, I-BiTTM DVD
- Where
- 2 sites in United Kingdom
- Volunteers
- 75 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Binocular Dysfunction, Vertical Heterophoria
Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria
The purpose of this study is to demonstrate whether, in patients diagnosed with Vertical Heterophoria, the symptoms of dizziness, headache and / or anxiety are reduced or eliminated when a kind of correction called vertical prism…
- Conditions
- Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
- Trial name
- NCT00785135
- Testing
- Lenses containing prismatic correction, Lenses not containing prismatic correction
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Vision Specialists of Birmingham
Amblyopia
CURESIGHT BINOCULAR AMBLYOPIA TREATMENT STUDY
Screening A child is considered for the study after undergoing a standard of care and study specific eye examinations (by a study investigator as part of standard of care) that identifies amblyopia appearing to meet the…
- Trial name
- NCT04785690
- Testing
- CureSight, Patching
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- NovaSight
Amblyopia
Binocular Dig Rush Game Treatment for Amblyopia
To compare the efficacy of 1 hour/day of binocular game play 5 days per week plus spectacle correction with spectacle correction only, for treatment of amblyopia in children 4 to <13 years of age.
- Trial name
- ATS20 (NCT02983552)
- Testing
- iPad®, Spectacle correction
- Where
- 62 sites in United States, Canada
- Volunteers
- 320 people
- Sponsor
- Jaeb Center for Health Research
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function
An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury
The early prospective study of Traq™ (an investigational binocular ophthalmic neurodiagnostic device) will measure binocular ocular functions (bilateral foveal fixation, foveal binocularity, and fovea-tracked saccadic latency) in…
- Conditions
- Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
- Trial name
- REB-001 (NCT07742878)
- Testing
- Binocular ophthalmic neurodiagnostic device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.