Clinical trials: Bilateral Cerebral Palsy
Cerebral Palsy
Evidence-based Physical Therapy in Children With Cerebral Palsy
The study aims to evaluate evidence-based practice behavior in usual care physical therapy in Flanders. Secondly, it aims to compare the effectiveness of a predefined physical therapy program based on evidence-based guidelines to…
- Trial name
- NCT02193386
- Testing
- No intervention, no follow-up, only registration, Intervention period
- Where
- Belgium
- Volunteers
- 16 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy
The Impact of Dosing Parameters on Motor Skill Acquisition and Retention in Bilateral Cerebral Palsy (BCP)
A recent systematic review found that therapeutic interventions that apply principles of motor learning with intense practice improve functional upper extremity movement in children with unilateral CP.
- Trial name
- NCT03940989
- Testing
- HABIT-ILE
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- Shriners Hospitals for Children
Cerebral Palsy
Effect of HABIT-ILE on the Body Function and Structures of Children With Cerebral Palsy
There is strong evidence that recent intensive interventions based on motor skill learning principles are efficient on functional and neuroplastic changes of children with cerebral palsy (CP).
- Trial name
- NCT04403490
- Testing
- HABIT-ILE, Conventional intervention
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Université Catholique de Louvain
Cerebral Palsy
Functional Effects and Impact on Motor Neuronal Activity of Early and Intensive Motrice (Hand and Arm Bimanual Intensive Therapy Including Lower Extremities: HABIT-ILE) Reeducation in Children With Pre-school Bilateral Cerebral Palsy
One of the urgent priorities in the field of pediatric neuro-rehabilitation is the development of efficient early motor interventions for children with cerebral palsy (CP).
- Trial name
- MOOV (NCT04362800)
- Testing
- MRI, Electro-Encephalography-High Density, 3D and EMG analysis
- Where
- 2 sites in France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Brest
Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
Effects of WALKBOT-G Robot-assisted Gait Training on Anticipatory Posture Adjustment Function and Balance With Cerebral Palsy
In children with cerebral palsy, the quality of walking decreases due to a decrease in the ability to control limbs, including walking, and coordination among various activities of daily living due to a decrease in functional…
- Conditions
- Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Bilateral Spastic Cerebral Palsy, Gait Disorders, Neurologic
- Trial name
- NCT04884386
- Testing
- robot-assisted gait training, conventional locomotion therapy
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Sahmyook University
Spastic Diplegia Cerebral Palsy
Evaluation of INRS With BCSK in Children With Spastic Bilateral Cerebral Palsy: a Randomized Controlled Trial.
A randomized control trial investigating "Biomechanical Correction of the Spine according to Kozyavkin" (BCSK) which is a part of the treatment concept "Intensive Neurophysiological Rehabilitation System" (INRS).
- Trial name
- NCT02166541
- Testing
- BCSK, Traditional spinal manipulation, INRS
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Cerebral Palsy, Bilateral Cerebral Palsy
Stepping to Understand Lower Limb Impairments in Bilateral Cerebral Palsy
The purpose of this study is to investigate lower limb impairments in children with bilateral cerebral palsy during stepping tasks.
- Conditions
- Cerebral Palsy, Bilateral Cerebral Palsy, Diplegic Cerebral Palsy
- Trial name
- NCT04957277
- Testing
- load modulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Periventricular Leukomalacia
Telerehabilitation of Working Memory in Children With Periventricular Leukomalacia and Bilateral Cerebral Palsy
Periventricular Leukomalacia (PVL) is a white matter lesion surrounding the lateral ventricles of the brain occurring in the prenatal period, associated with a disorder of movement and posture, known as bilateral cerebral palsy.
- Trial name
- NCT02342990
- Testing
- Cluster B CogMed: an home-based and computer-based solution to improve working memory deficit, Cluster A No training. Delay start of CogMed
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Fondazione Stella Maris
Bilateral Spastic Cerebral Palsy, Cerebral Palsy
Effect of Treadmill Gait Training Combined With Conventional Physiotherapy on Gait Performance and Functional Mobility in Children With Bilateral Spastic Cerebral Palsy: A Randomized Controlled Trial
Cerebral palsy is a neurological condition that affects movement, muscle control, and walking ability in children. Children with bilateral spastic cerebral palsy often experience increased muscle stiffness, difficulty with…
- Conditions
- Bilateral Spastic Cerebral Palsy, Cerebral Palsy, Spasticity Due to Cerebral Palsy, Gait Abnormality
- Trial name
- GAIT-CP (NCT07683338)
- Testing
- Treadmill Gait Training, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Syeda Khatoon e Jannat Welfare Foundation
Unilateral and Bilateral Cerebral Palsy
Quality of Life in Children With Cerebral Palsy
Cerebral Palsy (CP) is an umbrella term that defines a group of permanent disorders of movement and posture, happening during the developing foetal or infant brain.
- Trial name
- NCT06288958
- Testing
- Quality of Life and social participation in Italian children with CP
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Fondazione Stella Maris
Cerebral Palsy, Hip Surgery Corrective
Tranexamic Acid to Reduce Blood Loss After Varus Derotation Osteotomy
TABLO (Tranexamic Acid to reduce Blood Loss after varus derotation Osteotomy) is a clinical trial of postoperative tranexamic acid vs placebo in non-ambulatory children with cerebral palsy (CP) undergoing reconstructive hip…
- Conditions
- Cerebral Palsy, Hip Surgery Corrective, Tranexamic Acid Use, Blood Loss, Surgical
- Trial name
- TABLO (NCT07672158)
- Testing
- Tranexamic Acid (IV)
- Where
- Australia
- Volunteers
- 52 people
- Sponsor
- Murdoch Childrens Research Institute
Bilateral Spastic Cerebral Palsy
Kinesio Taping Versus Electrical Stimulation on Dysphagia in Bilateral Cerebral Palsy
The purpose of this study will be to compare the effect between kinesiotaping and neuromuscular electrical stimulation on dysphagia in children with bilateral spastic cerebral palsy.
- Trial name
- NCT07695350
- Testing
- Structured Oromotor Exercises, Kinesio Taping, Neuromuscular Electrical Stimulation
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Spastic Cerebral Palsy (sCP)
Bilateral Asymmetry of Respiratory Muscle Activity During Breathing in Children With Spastic Cerebral Palsy
This observational cross-sectional study investigates the bilateral asymmetry of respiratory muscle activity during breathing in children with spastic cerebral palsy (CP).
- Trial name
- NCT07777809
- Testing
- Surface Electromyography (sEMG) assessment
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Sahmyook University
Cerebral Palsy
Effect of Designed Physical Training After Selective Dorsal Rhizotomy on Motor Function of Ambulant Children With Spastic Diplegia
The management of cerebral palsy is complex and requires a multidisciplinary approach. Selective dorsal rhizotomy is a neurosurgical technique that aims to reduce spasticity in the lower limbs and improve motor function.
- Trial name
- NCT04997044
- Testing
- Concomitant physical rehabilitation, Standard Orthotic Management, selective dorsal rhizotomy
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Orthopedic Complications in Cerebral Palsy
Cohort of Children With Severe Cerebral Palsy
" Cohort CP " is a multicentre cohort study, initiated by the Hospices Civils de Lyon in September 2009. Population targeted are children with bilateral cerebral palsy, level GMFCS IV or V, aged from 2 to 10 years at inclusion.
- Trial name
- CPCohort (NCT01840930)
- Where
- France
- Volunteers
- 385 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy
Development of Kinect-assisted Home-based Bilateral Arm Training Program for Cerebral Palsy
The purpose of the present study is to develop a long term cost-effectiveness (efficient protocol, playful context, and practical strategy) training program for school-age children with Cerebral Palsy.
- Trial name
- NCT02801279
- Testing
- Conventional bilateral arm training, Kinect-based bilateral arm training
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cerebral Palsy
Implementation of a HABIT-ILE Intervention at Home for Children With Bilateral Cerebral Palsy
Intensive interventions based on the principles of motor skill learning, like Hand-Arm Bimanual Therapy Including Lower Extremities (HABIT-ILE), have demonstrated excellent effectiveness in improving motor function and daily life…
- Trial name
- HABITILEhome (NCT05740605)
- Testing
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE), Hand-Arm Bimanual Intensive Therapy Including Lower Extremities at home, Follow-up Hand-Arm Bimanual Intensive Therapy Including Lower Extremities
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Université Catholique de Louvain
Hemiplegic Cerebral Palsy
Use of Joystick-operated Ride-on-toys to Improve Affected Arm Use and Function in Children With Hemiplegic Cerebral Palsy
This research is being done to explore if modified, commercially available, joystick-operated, ride-on-cars can be used to promote bilateral arm function in children with hemiplegic Cerebral Palsy (CP).
- Trial name
- NCT05559320
- Testing
- Ride-on-toy navigation training, Upper extremity functional training
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Connecticut
Cerebral Palsy
Effect of a New Interactive Device on the Motor and Functional Abilities of Children With Bilateral Cerebral Palsy
Recent research has shown that interventions with assistive technologies lead to an improvement in the motor and functional abilities of children with cerebral palsy (CP).
- Trial name
- NCT04403464
- Testing
- HABIT-ILE with REAtouch®, HABIT-ILE without REAtouch®
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Université Catholique de Louvain