Clinical trials: Atrial Fibrillation
Thromboembolic Events
Association of Genetic Variants With Risk of Stroke in Patients With Atrial Fibrillation Off-anticoagulation
Life-long therapy with oral anticoagulants (OAC) is strongly recommended in AF patients receiving left atrial appendage isolation (LAAI) to prevent thromboembolic (TE) events.
- Trial name
- GSAF (NCT04115436)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation, Arrythmia
Design and Rationale of the Assessment of the MindMics Recording System
MindMics earbuds is a new technology designed enhance an individual's quality of life by continuously monitoring the heart rate, stress, and blood pressure allowing patients to make decisions regarding their health.
- Trial name
- NCT05103579
- Testing
- MindMics
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- MindMics Inc
Atrial Fibrillation (AF), Esophageal Perforation
Esophageal Safety of High and Very High Power Short Duration Pulmonary Vein Isolation: a Randomized Comparison of the 50W and 90W Power Settings
Pulmonary vein isolation (PVI) is the most effective means of maintaining sinus rhythm in atrial fibrillation (AF), while a widely used approach to PVI is point-by-point radiofrequency (RF) catheter ablation.
- Conditions
- Atrial Fibrillation (AF), Esophageal Perforation, Esophageal Perforation, Traumatic
- Trial name
- HPSD-Esophagus (NCT06617442)
- Testing
- Pulmonary vein isolation
- Where
- Hungary
- Volunteers
- 150 people
- Sponsor
- Semmelweis University
Atrial Fibrillation, Coronary Artery Disease
LAAO With DAPT Versus Antithrombotic Therapy
This study will retrospectively review and compare clinical outcomes between left atrial appendage occlusion with dual antiplatelet therapy versus conventional antithrombotic therapy in patients with atrial fibrillation…
- Trial name
- NCT03310801
- Testing
- ACP or Watchman
- Volunteers
- 480 people
- Sponsor
- Korea University Anam Hospital
Left Atrial Appendage, Non-Valvular Atrial Fibrillation
Canadian Left Atrial Appendage Closure Study
The purpose of the study is to demonstrate the safety and the rate of closure of the Ultrasept Left Atrial Appendage (LAA) Closure System for the percutaneous occlusion of the left atrial appendage in patients with non-valvular…
- Trial name
- CLASS (NCT03133806)
- Testing
- Ultrasept LAA Closure System
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Cardia Inc.
Atrial Fibrillation
Retrospective Observational Registry of Patients With Atrial Fibrillation From Vigo´s Health Area
Registry of all consecutive patients with atrial fibrillation from Heath Area of Vigo, since 2013 to 2020, in order to study therapy, mortality, cardiovascular complications and bleeding events.
- Trial name
- CardioCHUVI-AF (NCT04364516)
- Testing
- Anticoagulation
- Where
- Spain
- Volunteers
- 15,000 people
- Sponsor
- Hospital Álvaro Cunqueiro
Coronary Artery Bypass
Atorvastatin for Prevention of Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting Surgery
The purpose of this study is to determine whether pretreatment with atorvastatin protects against atrial fibrillation following off-pump coronary artery bypass graft surgery.
- Trial name
- NCT00611143
- Testing
- atorvastatin
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Samsung Medical Center
Cardiac Valve Disease, Aortic Valve Stenosis
Remote ECG Monitoring of TAVI Patients
After surgery, patients who undergo transcatheter aortic valve implantation (TAVI) are at risk of developing cardiac arrhythmias such as heart blocks and atrial fibrillation.
- Trial name
- NCT03810820
- Testing
- mobile Cardiac Arrhythmia Diagnostics Service (m-CARDS)
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Population Health Research Institute
Sleep Disorders
Validation of Ambulatory Sleep Test (WP200/U) Compared In-lab Sleep Testing in Cardiac Subjects
Subjects with cardiac disorders will be tested in the sleep laboratory with a conventional full-night PSG recording along with WP 200/WP200U ambulatory sleep diagnostic device in a synchronized manner.
- Trial name
- NCT02369705
- Where
- 10 sites in United States, Canada and 2 more
- Volunteers
- 200 people
- Sponsor
- Itamar-Medical, Israel
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Germany)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Phenprocoumon for the first…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947959
- Testing
- Rivaroxaban (Xarelto, Bay59-7939), Standard of care
- Where
- Germany
- Volunteers
- 665,533 people
- Sponsor
- Bayer
Atrial Fibrillation, Lone Atrial Fibrillation
Atrial Fibrillation in Young Patients: a Prospective Multicentre Registry
Atrial fibrillation is a rare cardiac arrhythmia in young (i.e. <= 35-year-old) patients. Etiological factors, current management and mid- to long-term outcomes remain unknown.
- Trial name
- YOUNG-AF (NCT04776759)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Atrial Fibrillation Ablation Using PENTARAY Catheter
Predictors of Atrial Fibrillation Recurrence After Ablation Using PENTARAY Catheter
CARTO represent a new way of 3D electroanaromic mapping for AF which has improved safety and success rate of AF ablation compared with other conventional methods of AF ablation as it provide accurate visualization of atrial…
- Trial name
- NCT05101980
- Volunteers
- 20 people
- Sponsor
- Assiut University
Stroke, Coronary Artery Disease
Cerebral Artery Stenosis, Coronary Artery Disease and Arrhythmia
There are many reports about the association of coronary artery disease (CAD) and cerebral artery stenosis (CAS), which had been proved to induce stroke and cognition decline after the revascularization including coronary bypass…
- Conditions
- Stroke, Coronary Artery Disease, Arrhythmia
- Trial name
- NCT00247533
- Testing
- Digital subtraction angiography and 24-hour simultaneous recorder of electrocardiograph
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Paroxysmal Atrial Fibrillation
Ultrasensitive Electroanatomic Mapping to Adjudicate Endpoints for Ablation In Paroxysmal AF Patients Using Cryoballoon
Ultrasensitive Electroanatomic Mapping to Adjudicate Endpoints for Ablation In Paroxysmal AF Patients Using Cryoballoon
- Trial name
- NCT04109053
- Sponsor
- BayCare Health System
Atrial Fibrillation (AF), Tricuspid Regurgitation (TR)
Efficacy of Early Rhythm Control in AF With TR Patients
Atrial fibrillation is frequently accompanied by tricuspid regurgitation and may contribute to right atrial and tricuspid annular remodeling, leading to progression of tricuspid regurgitation and adverse clinical outcomes.
- Trial name
- TRAF (NCT07607093)
- Testing
- Anti-arrhythmic drugs for rhythm control, DC cardioversion, catheter ablation for rhythm control, Usual care
- Where
- South Korea
- Volunteers
- 5,800 people
- Sponsor
- Samsung Medical Center
Cardiovascular Diseases, Heart Diseases
Epidemiology of Symptomatic Arrhythmias
To acquire a better understanding of the spontaneous clinical behavior of paroxysmal tachycardia by studying epidemiologic features of symptomatic tachycardia patients.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Atrial Fibrillation, Arrhythmia
- Trial name
- NCT00005237
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Myocardial Infarction
Development and Validation of a Risk Prediction Model for Ischemic Stroke in Acute Myocardial Infarction Without Comorbid Atrial Fibrillation
Study Goal: This observational study aims to develop a tool to predict the risk of ischemic stroke(stroke caused by a blood clot) in people who survive a heart attack and do not have irregular heartbeats (atrial fibrillation) .
- Trial name
- NCT07171892
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Atrial Fibrillation
Atrial Fibrillation Rate Control Therapy Guided By Continuous Ambulatory Monitoring
The purpose of this study is to demonstrate that the use of a continuous ambulatory monitoring device will reduce both the time to effective rate control and the health care expenditures associated with standard methods of rate…
- Trial name
- NCT00115843
- Testing
- Mobile Cardiac Outpatient Telemetry
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
ECG Monitoring
Biomedical Shirt-based ECG Monitoring
Cardiovascular diseases (CVD) are associated with high healthcare costs, as well as are a leading cause of mortality and hospitalizations.
- Trial name
- ECG-shirt (NCT03068169)
- Where
- 3 sites in Poland
- Volunteers
- 220 people
- Sponsor
- Medical University of Warsaw
Atrial Fibrillation
The Value of add-on Arrhythmia Surgery in Patients With Atrial Fibrillation Undergoing Cardiac Surgery
The hypothesis being studied is that add-on arrhythmia surgery in patients with atrial fibrillation (AF) undergoing valvular or coronary surgery improves quality of life, is cost-effective, reduces perioperative and long-term…
- Trial name
- NCT01019759
- Testing
- pulmonary vein isolation
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center