Clinical trials: Astigmatism
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Refractive Errors
Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses
The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric)…
- Trial name
- NCT06462456
- Testing
- Verofilcon A spherical soft contact lenses, Verofilcon A toric soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- Alcon Research
Cataract
Total Corneal Astigmatism Prevalence in Cataract Patients
The purpose of this study is to report the prevalence data for total corneal astigmatism (TCA) in cataract surgery candidates.
- Trial name
- NCT06148857
- Testing
- IOLMaster 700
- Where
- China
- Volunteers
- 11,000 people
- Sponsor
- Peking University Third Hospital
Astigmatism
Bilateral Dispensing Study of MyDay Toric, 1-day Acuvue Moist for Astigmatism, and Dailies Aquacomfort Plus Toric Lenses
Bilateral dispensing study of MyDay Toric, 1-day Acuvue Moist for Astigmatism, and Dailies Aquacomfort Plus Toric lenses
- Trial name
- NCT03134248
- Testing
- Dailies Aquacomfort Plus Toric, 1-Day Acuvue Moist for Astigmatism, MyDay Toric
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Myopia
Acuity 200™ (Fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
The objective of this clinical investigation is to collect scientifically valid safety and effectiveness data on the Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear.
- Trial name
- Acuity200OK (NCT06009458)
- Testing
- Acuity 200™ (fluoroxyfocon A) Orthokeratology Contact Lens for Overnight Wear
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 387 people
- Sponsor
- Acuity Polymers, Inc.
Astigmatism Bilateral
A Bilateral Dispensing Comparison of Comfilcon A Over Senofilcon C Contact Lenses
The aim of this study is to evaluate the subjective acceptance of Comfilcon A contact lenses when worn on a daily wear modality over one month.
- Trial name
- NCT03684928
- Testing
- Comfilcon A (test), Senofilcon C (control)
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Astigmatism
Clinical Evaluation of Two Toric Contact Lenses in Current Non-toric Lens Users
The purpose of this study is to evaluate the clinical performance, defined as successful fit, of two toric contact lenses (one daily disposable and the other daily wear reusable contact lens to correct astigmatism) in current…
- Trial name
- NCT01180998
- Testing
- Senofilcon A Toric (AOfA), Etafilcon A Toric (1DAMfA)
- Where
- 18 sites in United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Keratoconus, High Myopia
Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging
The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.
- Trial name
- NCT06739018
- Testing
- pentacam scheimpflug tomography
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Ametropia, Myopia
Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT06408649
- Testing
- Lehfilcon A spherical contact lenses, Lehfilcon A toric contact lenses
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Visual Acuity, Astigmatism
LFR-260 vs Traditional Phoropter in Visual Acuity Testing
The purpose of this study is to establish if LFR-260 (investigational device) is not inferior in effectiveness to a traditional phoropter (control device) when applied in visual acuity test in subjects undergoing a full routine…
- Conditions
- Visual Acuity, Astigmatism, Anisometropia
- Trial name
- NCT05259163
- Testing
- LFR-260 portable phoropter, Traditional phoropter (SOC)
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolution Optiks Limited
Myopia (Disorder), Astigmatism
Optical Quality of the Cornea in Orthokeratology
Analyzing Optical Quality After the Use of Overnight Orthokeratology (Ortho-K)
- Trial name
- COPCORTO (NCT06775509)
- Testing
- Ortho-K
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Congenital Cataract
Reduction of Corneal Astigmatism With Toric Intraocular Lens Implantation in Congenital Cataract
This study was conducted to evaluate changes of reduction of corneal astigmatism with toric intraocular lens(IOL) in congenital cataract.
- Trial name
- NCT02040129
- Testing
- Acrysof Toric IOL
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Kyungpook National University Hospital
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in gas permeable lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912781
- Testing
- FID 120947A contact lens disinfecting solution, Boston Simplus multi-action solution, Gas permeable contact lenses
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Hyperopic Astigmatism
Effect of WRAD Lens on Axial Growth and Refraction in Low-hyperopic Chinese Children
Myopia is one of the most common visual impairments worldwide.This not only poses long-term risks to individual health but also imposes significant medical and economic burdens on society.
- Trial name
- NCT07682974
- Testing
- With-the-Rule Astigmatic Defocus Lens, With-the-Rule Astigmatic Defocus Lens (Non-plano), Single Vision
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- He Eye Hospital
Keratoconus, Keratoconus, Artificial Intelligence, Support Vector Machine
Predicting Manifest Astigmatism in Keratoconus Patients.
The cornea of the human eye has several functions. It is transparent to allow light into the eye and its shape focuses the incoming light onto the retina.
- Trial name
- NCT06798779
- Testing
- Glasses, Corneal topography
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Amblyopia Bilateral, Hyperopia of Both Eyes
Hyperopia Detection GCK With Glow Fixation
"GoCheck Kids" has added to its iPhone 7+ smart phone with flash concentrator a non-accommodating glow box fixation target. In pediatric eye patients, the "GCK" with glow box is compared to cycloplegic refraction as well as…
- Conditions
- Amblyopia Bilateral, Hyperopia of Both Eyes, Astigmatism Bilateral, Accommodation Disorder
- Trial name
- NCT04297969
- Testing
- objective pediatric vision screen "GCK glow fixation"
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- Alaska Blind Child Discovery