Clinical trials: Apnea, Sleep
Obstructive Sleep Apnea Syndrome, Cleft Lip/Palate
A Study to Examine the Relationship Between Sleep Apnea and Cleft Lip/Palate
The study is to examine the relationship between sleep apnea and neurocognitive behaviors in children with cleft lip/palate. Describe the incidence and severity of obstructive sleep apnea in an unselected population of grade…
- Trial name
- NCT00156442
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Obstructive Sleep Apnea of Child
Cytokine Persistence as a Marker of Inflammation in the at Risk, Low Socioeconomic Status Pediatric Population
The investigators wish to study the role of persistent markers of inflammation in executive function in young children during critical periods of synaptogenesis (ages 2-3).
- Trial name
- NCT03134300
- Testing
- Cytokine from blood
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Sleep Apnea, Obstructive
The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention
This research study aims to find out the effect of REPOSE, a patient navigation intervention, on the receipt of equitable care among children with a broad range of socioeconomic and rural/urban status with Sleep Disordered…
- Trial name
- NCT06828835
- Testing
- Reach for Equity in Pediatric Obstructive Sleep Evaluation (REPOSE), Usual Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Medical University of South Carolina
Apnea, Sleep Apnea Syndromes
Oropharyngeal Exercises and Post-Stroke Obstructive Sleep Apnea
This study evaluates the feasibility and effectiveness of an oropharyngeal exercise (O-PE) regimen in treating post-stroke obstructive sleep apnea, as an alternative therapy to continuous positive airway pressure (CPAP).
- Conditions
- Apnea, Sleep Apnea Syndromes, Sleep Apnea, Obstructive, Stroke
- Trial name
- NCT04212260
- Testing
- Oropharyngeal exercises
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Sunnybrook Health Sciences Centre
Obstructive Sleep Apnea Syndrome
Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children
The purpose of this study is to investigate the effect of treatment with a steroid and antibiotic on the size of the tonsils and symptoms of children with OSAS.
- Trial name
- NCT00456339
- Testing
- Prednisolone and amoxicillin/clavulanate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Sleep-disordered Breathing (SDB)
Sleep-disordered Breathing and Neurocognitive Assessment in Children and Young Adults
One of main problems in the management of sleep-disordered breathing (SDB) in children and young adults is their screening, and the absence or the weak correlation between clinical symptoms and polysomnography (PSG).
- Trial name
- TRSPed (NCT04971850)
- Testing
- Sleep study
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pediatric Obstructive Sleep Apnea Syndrome
Investigating the Safety of Post-surgical Analgesics in Children With Obstructive Sleep Apnea
Every year thousands of young children with obstructive sleep apnea undergo surgery which requires them to be prescribed pain medication.
- Trial name
- NCT01680939
- Testing
- Morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Obstructive Sleep Apnea
Prevalence of Sleep Apnoea in Adolescents
Obstructive sleep apnoea (OSA) is associated with a variety of important complications, namely cardiovascular, neurocognitive and metabolic disturbances. The prevalence of OSA is well studied in children and adults.
- Trial name
- NCT03895775
- Where
- Hong Kong
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnoea
The Use of Oral Appliances as an Adjunct to Continuous Positive Airway Pressure (CPAP) in the Treatment of Obstructive Sleep Apnoea
This study will look at whether patients with OSAHS already successfully treated with nasal CPAP could successfully use an oral appliance as a short-term treatment alternative and whether patients who could use an oral appliance…
- Trial name
- NCT00358605
- Testing
- The Klearway™ oral appliance
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of British Columbia
Obstructive Sleep Apnea
To Study the Impact of CPAP on Gait Parameters in OSA Patients
To study the impact of CPAP therapy on gait in patients with obstructive sleep apnea syndrome.
- Trial name
- OSA_Gait (NCT02061046)
- Testing
- CPAP therapy
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
Lung Diseases, Sleep Apnea Syndromes
Prevalence of Sleep-Disordered Breathing in Children
To investigate the prevalence and clinical significance of sleep-disordered breathing (SDB) in children.
- Trial name
- NCT00022789
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Milton S. Hershey Medical Center
Sleep Apnea
Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea
The purpose of this research study is to determine the effect of chronic nighttime low oxygen saturations on selected body systems (liver) that break down drugs in children with obstructive sleep apnea syndrome (OSAS).
- Trial name
- NCT00310323
- Testing
- Dextromethorphan, Caffeine
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Virginia Commonwealth University
Obstructive Sleep Apnea (OSA), Rapid Maxillary Expansion
Changes in Polysomnography and Rhinomanometry Parameters After Rapid Maxillary Expansion or Adenotonsilectomy in Children With Obstructive Sleep Apnea
Adenotonsillectomy (AT) is considered the most effective and the standard treatment for Obstructive Sleep Apnea (OSA) in children.
- Conditions
- Obstructive Sleep Apnea (OSA), Rapid Maxillary Expansion, Polysomnography
- Trial name
- NCT07069543
- Testing
- Adenotonsillectomy, Rapid maxillary expansion
- Where
- Brazil
- Volunteers
- 51 people
- Sponsor
- Federal University of Minas Gerais
Obstructive Sleep Apnea Hypopnea Syndrome
Contribution of Drug Induced Sleep Endoscopy of Pediatric Obstructive Sleep Apnea Hypopnea Syndrome
The role of drug-induced sleep endoscopy (DISE) in the management of obstructive sleep apnea hypopnea syndrome (OSAHS) is not precisely defined for children.
- Trial name
- ESSI (NCT03845062)
- Where
- France
- Volunteers
- 31 people
- Sponsor
- University Hospital, Montpellier
Obstructive Sleep Apnea, Down Syndrome
Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome
This is an open-label study of the combination of atomoxetine and oxybutynin (ato-oxy) in children with Down syndrome and obstructive sleep apnea (OSA) documented by polysomnography (PSG).
- Trial name
- MOSAIC (NCT05933603)
- Testing
- Atomoxetine and Oxybutynin (ato-oxy)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Arizona
Obstructive Sleep Apnea
Fentanyl Test and A Short OSAS Screening Scale for Severe Obstructive Sleep Apnea
The aim of this study was to estimate and compare the value of the preoperative fentanyl test and the short OSAS screening scale to diagnose severe obstructive sleep apnea；and to observe the required amount of hydromorphone and…
- Trial name
- NCT03705780
- Testing
- the short OSAS scale, fentanyl test
- Where
- China
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Obstructive Sleep Apnea
Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
This research study is designed to learn, first, whether two anesthetics have different effects on collapse seen within the upper airway during sleep endoscopy.
- Trial name
- NCT05303987
- Testing
- Propofol sedation, Dexmedetomidine sedation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Erin Kirkham
Hypertension, Obstructive Sleep Apnea
Hypertension and Sleep Disordered Breathing in Pediatrics
The primary objective is to determine the prevalence of sleep disordered breathing in children with primary hypertension or pre hypertension.
- Trial name
- NCT00990899
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- NYU Langone Health
Obstructive Sleep Apnea
Effect of Montelukast Therapy in Obstructive Sleep Apnea(OSA) Children
The investigators leading hypotheses are: Oral therapy with montelukast may lead to improved sleep study findings in children with mild to moderate Obstructive Sleep Apnea Syndrome (OSAS) who require surgical removal of adenoids…
- Trial name
- 32543 (NCT01027806)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Chicago