Clinical trials: Antenatal Care
Covid19, Pregnancy Related
Safety, Testing/Transmission, and Outcomes in Pregnancies With COVID-19
Pregnant women are a vulnerable and high-risk population, as COVID-19 is associated with an increased risk preterm birth, cesarean section, and maternal critical care.
- Conditions
- Covid19, Pregnancy Related, Maternal Complication of Pregnancy, Coronavirus
- Trial name
- STOPCOVID19 (NCT04718220)
- Testing
- Antibody testing for SARS-CoV-2 IgG, Testing for SARS-CoV-2 RNA, Testing for SARS-CoV-2 IgM/IgG
- Where
- United States
- Volunteers
- 448 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Fetal Conditions
Early Pregnancy Ultrasound Parameters Including Corpus Luteum Doppler in Prediction of First Trimester Pregnancy Outcome in Spontaneous Pregnancies.
The synthesis of progesterone by corpus luteum is extremely important for the maintenance of normal pregnancy in the first seven weeks.
- Trial name
- NCT07204028
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maternal Dietary Diversity, Iron-Folic Acid Supplementation
Assessing the Feasibility of Integrating a Package of Maternal Nutrition Interventions Into Antenatal Care Services in Burkina Faso
Alive \& Thrive (A\&T) is an initiative that supports the scaling up of nutrition interventions to save lives, prevent illnesses, and contribute to healthy growth and development through improved maternal nutrition, breastfeeding…
- Conditions
- Maternal Dietary Diversity, Iron-Folic Acid Supplementation, Early Initiation of Breastfeeding
- Trial name
- NCT04155437
- Testing
- Health Facility Level Interventions, Community Level Interventions, Health System Level Interventions
- Where
- United States
- Volunteers
- 8,110 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Premature Birth, Premature Infant
Growing Little PEAPODS Study
The goal of this clinical trial is to learn more about how the food and nutrition babies receive while in the Neonatal Intensive Care Unit (NICU) influences their ability to gain weight and fat-free mass, and their future growth…
- Conditions
- Premature Birth, Premature Infant, Premature, Intrauterine Growth Restriction
- Trial name
- NCT06226051
- Testing
- PEAPOD Infant Body Composition measuring device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Wisconsin, Madison
Oral Glucose Tolerance Test, Low Birth Weight
Association Between Low Plasma Glucose After Oral Glucose Tolerance Test in Pregnancy With Impaired Fetal Growth
Objective: To study the association of low maternal plasma glucose in 2 hour 75 g oral glucose tolerance test (OGTT) in women with impaired birth weight and determinate if this result is predictive of low birth weight (<10th…
- Trial name
- NCT04144595
- Testing
- 2 hour 75 g Oral glucose tolerance test
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Maternal Health
Mobile Health Intervention (Support-moms) in Antenatal Care to Improve Maternal Health in Uganda
High maternal mortality is a major public health problem in many settings. Because of low antenatal care (ANC) and skilled birth usage, Ugandan women and their children suffer from high maternal and perinatal mortality.
- Trial name
- Support-Moms (NCT05940831)
- Testing
- Support-Moms, Control
- Where
- 2 sites in Uganda
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Intrapartum Fetal Distress, Neonatal Asphyxia
Oral Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings
The goal of this feasibility pilot clinical trial is to determine if sildenafil citrate 50mg orally, up to three times during labor, can: 1) reduce perinatal mortality and/or bag and mask ventilation at birth in planned vaginal…
- Conditions
- Intrapartum Fetal Distress, Neonatal Asphyxia, Intrapartum Asphyxia, Instrumental Delivery; Affecting Fetus
- Trial name
- NCT06522854
- Testing
- Sildenafil 50 mg Oral Tablet
- Where
- 4 sites in Nigeria
- Sponsor
- University of Alabama at Birmingham
Immunization; Infection, Pregnancy Related
VAX-MOM COVID-19: Increasing Maternal COVID-19 Vaccination
COVID-19 infection during pregnancy is associated with increased risk of pre-eclampsia, preterm birth and stillbirth. Pregnant people with COVID-19 have a higher rate of ICU admission and intubation than those who are not…
- Conditions
- Immunization; Infection, Pregnancy Related, COVID-19
- Trial name
- NCT05570630
- Testing
- VAX-MOM COVID-19 Intervention, Standard of Care
- Where
- United States
- Volunteers
- 6,911 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Impacted Fetal Head, Full Dilatation Caesarean Section
Lifting the Impacted Fetal Head; the Fetal Pillow and Tydeman Tube Trial
A single centre prospective observational comparison trial to compare the Tydeman Tube and Fetal Pillow, to aid delivery of the impacted fetal head at full dilatation caesarean section, and to evaluate the use of the Tydeman Tube…
- Trial name
- LIFT (NCT07372768)
- Testing
- Fetal Pillow, Tydeman Tube
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Anxiety, Pregnancy Related
The Effect of Web-based Mindfulness-based Stress Reduction Program on Pregnant Women
Pregnancy is a period in which physiological and psychological changes are experienced and discomforts related to these changes are observed, and comfort is affected for the pregnant.
- Trial name
- NCT05441124
- Testing
- Mindfullness Based Stress Reduction (MBSR) intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Amasya University
Birth Weight
Healthy Mums, Healthy Babies: Multiple Micronutrient Supplementation in Ethiopia
Background: This programme effectiveness study responds to the need for evidence on the effect on birthweight of switching from iron-folic acid supplementation (IFA) to multiple micronutrient supplementation (MMS) as part of…
- Trial name
- NCT05708183
- Testing
- Multiple micronutrient supplementation (MMS), Iron folate supplementation (IFA)
- Where
- 6 sites in Ethiopia
- Volunteers
- 25,620 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Maternal Morbidity and Mortality, Stillbirth and Neonatal Mortality
Emergency Obstetric and Neonatal Care: The EmONC Trial
The objective of this cluster randomized controlled trial is to reduce maternal and neonatal mortality by increasing access to and improving the quality of obstetric and neonatal care for pregnant women in study clusters.
- Trial name
- EmONC (NCT01073488)
- Testing
- Community Mobilization, HBLSS and facility improvement
- Where
- 7 sites in Argentina, Guatemala and 4 more
- Volunteers
- 267,181 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Fetal Hemoglobin, Thalassemia Major
Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta Thalassemia
The project "Unraveling the Impact of Thalidomide at Diverse Doses in Transfusion Dependent Beta Thalassemia" investigates the safety and efficacy of low-dose thalidomide in managing beta thalassemia, a genetic disorder causing…
- Conditions
- Fetal Hemoglobin, Thalassemia Major, Genetic Disease
- Trial name
- BTM (NCT06490627)
- Testing
- Thalidomide
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
Lipid Profile, Neonates
Omega-3 on Lipid Profile and Serum Leptin Level n Neonates With Intrauterine Growth Restriction
The aim of our study will demonstrate the effect of omega 3 supplementation on serum lipid profile level and leptin level in neonates with Intrauterine Growth Restriction( IUGR)
- Conditions
- Lipid Profile, Neonates, Intrauterine Growth Restriction
- Trial name
- NCT05242107
- Testing
- Omega-3 supplement group, Full feeding without receiving any supplementation group
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
HIV
Early ART Initiation Among HIV-positive Pregnant Women in Central Mozambique
The overall objective of the study is to develop and test a pilot intervention in central Mozambique to implement the new WHO "Option B+" guidelines that seek to increase the proportion of HIV-positive pregnant women in six…
- Trial name
- NCT02371265
- Testing
- Adherence and retention package
- Where
- Mozambique
- Volunteers
- 761 people
- Sponsor
- University of Washington
Fetal Distress With Antenatal Problem, Fetal Growth Retardation
Validation of Sensors for Long-term Non-Invasive Fetal Monitoring
A multidisciplinary team of a doctor and engineers have developed a new sensor that will be able to detect mothers' and babies' heartbeat and babies movements in late pregnancy.
- Trial name
- NCT06952777
- Testing
- Non-adhesive capacitively-coupled sensors
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Cardiometabolic Diseases, Obesity
Prenatal Programming of Childhood Obesity and Cardio Metabolic Disorders
This is a prospective 11-17 -years follow-up of two existing pregnancy cohort (PREDO) and prevention (RADIEL) studies. The main objective is to investigate the associations between maternal overweight, obesity, hypertensive…
- Trial name
- NCT05223530
- Where
- Finland
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Preterm Premature Rupture of Membranes
Indomethacin Versus Placebo in Women With Preterm Premature Rupture of Membranes (PPROM)
The purpose of this study is to determine if the short term use of indomethacin will reduce the number of women delivering within 48 hours when given to women with preterm premature rupture of membranes (PPROM) between 24- 32…
- Trial name
- NCT00466128
- Testing
- indomethacin
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Intrauterine Growth Restriction, Fetal Anomaly
Diagnosis and Management of Intrauterine Growth Restriction and Congenital Anomalies
The purpose of this prospective cohort study is to build a large platform that includes clinical information (prenatal diagnosis and postnatal follow-up data) and biological specimen banks of fetuses/infants with IUGR or…
- Conditions
- Intrauterine Growth Restriction, Fetal Anomaly, Chromosomal Anomalies, Pregnancy
- Trial name
- NCT03398629
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Fetal Growth Restriction
Evaluation of Fetal Heart
Evaluation of fetal cardiac functions in cases complicated with growth restriction
- Trial name
- NCT07760194
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Assiut University