Clinical trials: Anesthesia,General
Cystic Fibrosis
Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia
Four methods are routinely used to monitor CO2 in patients. End tidal CO2 (EtCO2) is monitored through the endotracheal tube during general anesthesia.
- Trial name
- NCT03734822
- Testing
- End tidal CO2 (EtCO2), Transcutaneous CO2 (TCO2), Capillary CO2 (CapCO2)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Nationwide Children's Hospital
Anesthetic, Sevoflurane
Sevoflurane Concentrations in Children
The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.
- Conditions
- Anesthetic, Sevoflurane, Age
- Trial name
- NCT06510803
- Testing
- The washin of sevoflurane in the GE Ohmeda workstation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Preoperative Sedation
Intranasal Dexmedetomidine Premedication in Children
BACKGROUND INFORMATION AND RATIONALE Pediatric patients scheduled for dental procedures under general anesthesia can have significant anxiety before the procedure.
- Trial name
- NCT02250703
- Testing
- Midazolam, Dexmedetomidine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Mississippi Medical Center
Anesthesia
SedLine Engineering Data Collection Study in Pediatric Patients Undergoing General Anesthesia or Sedation
The purpose of the study is to collect EEG data with the Masimo SedLine device along with vital signs, patient demographics, anesthetic record and surgical procedure during general anesthesia or sedation.
- Trial name
- NCT03128931
- Testing
- Pediatric SedLine forehead EEG sensor
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Masimo Corporation
Post-Operative Nausea and Vomiting
A Study of Kytril (Granisetron) in the Prevention of Post-Operative Nausea and Vomiting (PONV) in Pediatric Subjects Undergoing Tonsillectomy or Adenotonsillectomy
This 2 arm study will evaluate the efficacy and safety of a single intravenous injection of Kytril in preventing postoperative nausea and vomiting (PONV) in children.
- Trial name
- NCT00231478
- Testing
- granisetron
- Where
- 11 sites in United States
- Volunteers
- 171 people
- Sponsor
- Hoffmann-La Roche
Ventilation
A Comparison of Different Ventilation Strategies in Infants Using the PLMA™
The purpose of this research study is to compare difference between breathing by oneself or with the partial help from an anesthesia machine in infants under general anesthesia.
- Trial name
- NCT03235817
- Testing
- Spontaneous ventilation, Pressure support ventilation, Pressure control ventilation
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Wake Forest University
Supracondylar Fractures
A Comparison of UGSB and GA to IV Narcotics and GA for Post-Op Pain in Children With Supracondylar Fractures.
This study compares nerve blocks to IV pain medicines in children with broken arms. We are trying to see if blocking the nerves in the broken arm results in better pain control and less side effects than injections of morphine…
- Trial name
- NCT02056288
- Testing
- Fentanyl, Ropivacaine
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Children Requiring MRI
Pediatric Temperature Variation in the MRI Scanner Under General Anesthesia
The number of children undergoing MRI imaging has increased significantly in the past years, because many young children cannot stay still for the duration of the scan, have difficulty tolerating the confined space and the noise…
- Trial name
- NCT01119248
- Testing
- axillary temperature before MRI and after the MRI
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rutgers, The State University of New Jersey
Anesthesia, Pain
Near Infrared Spectroscopy Cortical Response to Noxious and Auditory Stimuli in Subjects Under General Anesthesia
The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to…
- Trial name
- NCT02703090
- Testing
- Remifentanil, Normal saline
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Boston Children's Hospital
Anesthesia, General, Neuromuscular Blockade
Pharmacokinetic-pharmacodynamic Analysis of Sugammadex in Children
This study administers sugammadex sodium to pediatric patients under general anesthesia with rocuronium. Pharmacokinetic and pharmacodynamic analysis are performed based on plasma concentration of sugammadex sodium and monitoring…
- Trial name
- NCT03943888
- Testing
- Sugammadex Injection 2mg/kg, Sugammadex Injection 4mg/kg, Sugammadex Injection 8mg/kg
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Surgeries Undergoing General Anesthesia
Study: Study to Compare Video Miller Device to Direct Laryngoscopy
The purpose of this study is to compare: the standard pediatric intubation instrument (Miller blade) used as direct laryngoscopy during tracheal intubation to the VideoMiller device (the standard pediatric blade with a camera…
- Trial name
- NCT01371032
- Testing
- VideoMiller, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Cedars-Sinai Medical Center
Pain, Procedural
The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
The purpose of this study is to compare patient responses during and after surgery when local anesthetic is used for dental treatment under general anesthesia (GA) and when it is not used.
- Trial name
- NCT04500158
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Virginia Commonwealth University
Hypothermia
An Epidemiology Survey on the Incidence of Perioperative Hypothermia
The purpose of this study is to understand and grasp the incidence rate of hypothermia during perioperative period of elective operations under general anaesthesia in Beijing.
- Trial name
- NCT01913041
- Where
- China
- Volunteers
- 869 people
- Sponsor
- Jie YI
Airway Complication of Anaesthesia
Effectiveness and Safety of the Levitan Scope for Laryngoscopy and Tracheal Intubation With a Simulated Difficult Airway
A laryngoscope is a medical instrument that is used to get a view of the voice box and the space in between the vocal cords. A laryngoscope is used to place a breathing tube into the trachea (windpipe or airway) to protect the…
- Trial name
- NCT01491984
- Testing
- Laryngoscopy order: 1) MAC, 2) Levitan, Laryngoscopy order: 1) Levitan, 2) MAC
- Volunteers
- 105 people
- Sponsor
- IWK Health Centre
Anesthesia, Depth of Hypnosis Monitoring
The Effect of DSA on Recovery of Anaesthesia in Children
In this randomised, blinded study, we will investigate the influence of DSA on recovery from general anaesthesia. DSA monitoring provides continuous information on depth of hypnosis.
- Trial name
- DSA-RCT-1 (NCT05525104)
- Testing
- Narcotrend Monitor (MT MonitorTechnik, Hannover, Germany)
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- Erasmus Medical Center
Myringotomy
Effect of Dexmedetomidine on Emergence Agitation in Children With or Without Tube Insertion Under General Anesthesia
The investigators are inviting your child to participate in this research study because your child is having myringotomy (putting a tiny incision in the eardrum with or without tube insertion) under general anesthesia.
- Trial name
- NCT01535287
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Martin Mueller
Sleep Apnea, Obstructive, Tonsillectomy
The Effect of Caffeine on Postextubation Adverse Respiratory Events in Children With Obstructive Sleep Apnea (OSA).
This is a research study using caffeine in children who have an obstructive sleep apnea (OSA). OSA means children who stop breathing during their sleep due to obstruction in their airway.
- Conditions
- Sleep Apnea, Obstructive, Tonsillectomy, Adenoidectomy, Postoperative Complications
- Trial name
- OSA (NCT00273754)
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- The University of Texas Health Science Center, Houston
Strabismus
The Effect of Povidone-iodine Ophthalmic Surgical Prep Solution on Respiration in Children Undergoing Strabismus Surgery With General Anesthesia.
Determine whether the application of povidone-iodine ophthalmic solution onto the ocular surface causes a change in respiration in children undergoing strabismus surgery with general anesthesia.
- Trial name
- NCT03349515
- Testing
- Provodine-Iodine Solution, Group B will receive three drops in each eye of ophthalmic balanced salt solution.
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Anxiety, Separation, Psychomotor Agitation
Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Nearly 50% of young children undergoing surgery exhibit high level of anxiety during induction of anesthesia because of exposure to unfamiliar environment and people and separation from parents.
- Trial name
- NCT02027844
- Testing
- Cartoon, parental presence
- Where
- South Korea
- Volunteers
- 117 people
- Sponsor
- Yeungnam University College of Medicine
Emergence Agitation, Pain
Can Acetaminophen Given 1-2 Hours to Children Before Ear Tube Surgery Reduce Agitation After Anesthesia?
Emergence agitation (EA) occurs in up to 67% of pediatric patients after anesthesia for bilateral myringotomy tubes (BMT, "ear tubes").
- Trial name
- NCT01737593
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles