Clinical trials: Ametropia
Astigmatism, Presbyopia
North American Comfilcon A Clinical Study
The main objective of this study is to demonstrate acceptable safety and effectiveness (performance) of comfilcon A Sphere, Toric, Multifocal, Toric Multifocal and Energys lenses, when used in the general population.
- Conditions
- Astigmatism, Presbyopia, Ametropia
- Trial name
- NCT06902584
- Testing
- comfilcon A Sphere lens, comfilcon A Toric lens, comfilcon A Multifocal lens
- Where
- 4 sites in United States
- Volunteers
- 102 people
- Sponsor
- CooperVision International Limited (CVIL)
Refractive Errors, Ametropia
Performance of Refractometers With Self-adjusting Lenses Compared to Cycloplegia in Children (REFRALENS)
This study aimed to compare refractive measurements using Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic…
- Trial name
- REFRALENS (NCT06668246)
- Testing
- Vision-S™ 700, an immersive and compact phoropter with a tunable-focus lens, and Vision-R™ 800, a phoropter with a tunable-focus lens without immersion, with cycloplegic refraction serving as the gold
- Where
- France
- Volunteers
- 43 people
- Sponsor
- University Hospital, Brest
Myopia, Ametropia
LED Low-Intensity Red Light for Myopia Control in Youth: Efficacy and Safety Study
The purpose of this clinical trial was to investigate the efficacy and safety of repetitive low-intensity single-wavelength red light from an LED light source in controlling myopia progression in children and adolescents.
- Trial name
- NCT07375589
- Testing
- Red light treatment with 1.6mW LED light source, Red light treatment with 0.001mW LED light source
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Ametropia
A Study to Evaluate the Clinical Performance and Safety of UNICON Silicone Hydrogel Daily Disposable Soft Contact Lenses
13 weeks, open-label, daily disposable contact lens dispensing study.
- Trial name
- NCT07322211
- Testing
- Treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 35 people
- Sponsor
- Unicon Optical Co. Ltd.
Ametropia, Myopia
Post-market Clinical Follow-up Study of Alcon TOTAL30® Contact Lenses (Lehfilcon A)
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to continuously assess the visual performance and safety of TOTAL30 Sphere and TOTAL30 for Astigmatism contact lenses in a real-world setting across a broad…
- Conditions
- Ametropia, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT06408649
- Testing
- Lehfilcon A spherical contact lenses, Lehfilcon A toric contact lenses
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Ametropia
Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children With a Smartphone/add-on Device in India
The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia.
- Trial name
- NCT06524115
- Testing
- Comparator device, Closed-field autorefractometer without cycloplegia, Distance visual acuity check using objective refraction without cycloplegia, Comparator device, Closed-field autorefractometer with cycloplegia
- Where
- India
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Essilor International
Ametropia
Optimization of a Photoretinoscopy Method for Determining the Objective Refraction of Children
The objective is to compare the refractive parameters of the photorefraction prototype device without cycloplegia with the refractive parameters of reference device, an autorefractometer with and without cycloplegia.
- Trial name
- NCT06295536
- Testing
- Comparator device, Closed-field autorefractometer
- Where
- Hong Kong
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Essilor International
Ametropia
Evaluation of Disinfecting Solutions and Protein Remover With a Silicone Hydrogel Lens
The purpose of this study is to determine if reduced lens deposits and increased comfort can be achieved by using Multipurpose disinfecting solutions (MPDS) in a no-rub format but in conjunction with an intensive cleaner, rather…
- Trial name
- NCT00754338
- Testing
- Alcon Opti-Free® RepleniSH® with Supraclens®, Alcon Opti-Free® RepleniSH®, B&L ReNu MultiPlus™
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia, Amblyopia
Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults
Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of…
- Conditions
- Myopia, Amblyopia, Refractive Error - Myopia Axial, Ametropia
- Trial name
- MCPT (NCT05957458)
- Testing
- Airdoc device of red light for Myopia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Ametropia
Ocular Responses to Short and Long-term Lens Wear
The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with…
- Trial name
- NCT00722891
- Testing
- Purevision Lenses with ReNu Multiplus, Purevision Lenses with Optifree RepleniSH
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Normal Subjects, Ametropia
Project Gullstrand - European Project for the Determination of Average Biometric Values of Human Eyes
The purpose of this study is to determine the average values of human ocular biometry and to correlate these values with visual function.
- Trial name
- Gullstrand (NCT01173614)
- Where
- Spain
- Volunteers
- 1,646 people, healthy volunteers welcome
- Sponsor
- European Vision Institute Clinical Research Network
Ametropia
Evaluation of the Performance of Non-molded Soft Contact Lenses
To evaluate the performance of the study soft lens for vision, comfort, physiology and lens surface properties.
- Trial name
- NCT00371787
- Testing
- Soft contact lens
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Ametropia
Contact Lens Wettability
The purpose of this study is to compare the wettability of contact lenses disinfected with three marketed contact lens care solutions.
- Trial name
- NCT00349063
- Testing
- soft contact lens, Soft contact lens multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Waterloo