Clinical trials: Alcoholism
Alcohol Use Disorder
Cannabidiol in Youth Alcohol Use Disorder
The goal of this study is to test cannabidiol (CBD) as a potentially effective candidate medication for youth alcohol use disorder (AUD).
- Trial name
- NCT05317546
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Abuse
A Community-Based Strategy for Preventing Underage Drinking
This project evaluates a combination of policy and social influence interventions to reduce adolescent alcohol use and its sequelae.
- Trial name
- NCT02448134
- Testing
- Youth Access
- Where
- United States
- Volunteers
- 7,379 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Alcohol Abuse, Cannabis Abuse
Trial of Computerized SBI to Reduce Teen Alcohol Use
The goal of this project is to test the effectiveness of a computer-facilitated alcohol screening and brief intervention (c-ASBI) system for 12- to 18-year-old primary care patients in a multi-site, randomized comparative…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Nicotine Dependence
- Trial name
- NCT01784627
- Testing
- c-ASBI
- Where
- 6 sites in United States
- Sponsor
- Boston Children's Hospital
Antisocial Behavior
Multisystemic Therapy-Emerging Adults (MST-EA) for Substance Abuse
This study's purpose is to examine the effectiveness of a promising intervention for emerging adults (EAs) with alcohol and other drug (AOD) abuse and justice involvement in achieving the ultimate outcome of reduced criminal…
- Trial name
- NCT03035877
- Testing
- Multisystemic Therapy-Emerging Adults, Enhanced Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 183 people
- Sponsor
- Chestnut Health Systems
Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency
The Whole Day First Grade Program
This five-year prevention services application is concerned with preventing substance abuse, comorbid mental and behavioral disorders, and school failure.
- Conditions
- Prevention of Drug Abuse and Dependency, Alcohol Abuse and Dependency, High Risk Sex Behavior, Smoking Tobacco
- Trial name
- NCT00257088
- Testing
- whole day first grade program
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- American Institutes for Research
Alcohol Use Disorder
Effect of Hypnotherapy in Alcohol Use Disorder Compared to Motivational Interviewing.
This study was carried out at an inpatient clinic in Norway. A six- week long treatment programme included intensive group therapy, but also five hours of individual therapy, given as motivational interviewing (MI).
- Trial name
- NCT03583788
- Testing
- Hypnotherapy, Motivational Interviewing
- Volunteers
- 31 people
- Sponsor
- Sykehuset Innlandet HF
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Alcohol Use Disorder
Citicoline in Youth Alcohol Use Disorder
The goal of this study is to evaluate how citicoline, an over-the-counter supplement, versus a placebo pill (i.e., an inactive pill) affects the immune system, brain, and cognition in adolescents who may use alcohol.
- Trial name
- NCT05870111
- Testing
- Citicoline (cytidine diphosphate-choline)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Alcohol Drinking, Alcohol Problem Drinking
Parent Feedback Intervention Targeting Student Transitions and Alcohol Related Trajectories (+) Efficacy Study
FITSTART (Feedback Intervention Targeting Student Transitions and Risk Trajectories) is a parent-based social norms intervention that has been shown to reduce risky drinking in incoming first year students.This program uses…
- Conditions
- Alcohol Drinking, Alcohol Problem Drinking, Parenting
- Trial name
- FITSTART+ (NCT04549454)
- Testing
- FITSTART+ PBI, General Parenting Advice
- Where
- United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Alcohol Consumption
Role of Dopamine in Response to Alcohol
This study will examine the role of the brain chemical dopamine in people's response to alcohol consumption. Dopamine is thought to influence whether people have a strong or weak response to alcohol and how pleasurable that…
- Trial name
- NCT00050219
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Use; Tobacco, Harmful, Alcohol Abuse
Dental and Medical Office iMET to Reduce Teen Tobacco, Alcohol, and Drug Use
The purpose of the project is to improve adolescent behavioral counseling services in healthcare settings with a new Internet/Intranet-based Motivational Enhancement Therapy (iMET) intervention that targets the use of tobacco…
- Conditions
- Use; Tobacco, Harmful, Alcohol Abuse, Drug Abuse
- Trial name
- NCT00907309
- Testing
- iMET, iMET/TE
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Boston Children's Hospital
Alcohol Abuse
Pilot Test of Computerized MET to Reduce Adolescent Alcohol Use
The goal of this project is to conduct a pilot study evaluating feasibility, acceptability, and estimating the effect size of a new computerized Motivational Enhancement Therapy (cMET) intervention for alcohol-involved adolescent…
- Trial name
- NCT01796158
- Testing
- cASBI+cMET, cASBI
- Where
- United States
- Sponsor
- Boston Children's Hospital
Alcohol Use Disorder
Promoting Medications for Alcohol Use Disorder on the General Medicine Service
Medications for Alcohol use disorder (MAUD) (acamprosate, naltrexone, and disulfiram) remain underutilized despite guideline recommendations and rising alcohol-related morbidity and mortality.
- Trial name
- NCT04287790
- Testing
- audit and feedback, educational meetings, and academic detailing to promote medication receipt, Acamprosate, naltrexone, or disulfiram
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Yale University
Alcohol Abuse, Substance Use
Adaptation and Evaluation of Bright Horizons
This study will test if a program called 'Bright Horizons' is effective at reducing binge substance use among adolescents. Bright Horizons is a culturally adapted intervention developed and tested through a partnership between…
- Trial name
- NCT05743699
- Testing
- Bright Horizons, Case Management
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Alcoholism
Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support
Hazardous drinking is common among Veteran primary care patients and increases risk for more costly and complex medical problems over the long-term. Yet, the vast majority of these Veterans go untreated.
- Trial name
- PS-Stand Down (NCT05473598)
- Testing
- Stand Down app, Peer-Supported Stand Down, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 234 people
- Sponsor
- VA Office of Research and Development
Alcohol and Substance-Related Mental Disorders
Effectiveness of an Evidence-based Stepped Care System for Alcohol and Other Drug Use Problems Among Congolese Refugees in Zambia
This is a randomized controlled trial (RCT) evaluating the effectiveness of a screening, brief intervention, and referral to treatment (SBIRT) stepped-care system in reducing unhealthy AOD use among Congolese refugees and the…
- Trial name
- NCT05471921
- Testing
- SBIRT, Treatment as usual
- Where
- 2 sites in United States, Zambia
- Volunteers
- 400 people
- Sponsor
- Columbia University
Alcohol Dependence, Drug Dependence
LINK: Aftercare Monitoring Project
The prevalence of substance use disorders (SUD) in the VA is rising, making SUD(s) among the most commonly diagnosed disorders in the VA.
- Trial name
- NCT00265512
- Testing
- Telephone Case Monitoring, Continuing Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 667 people
- Sponsor
- VA Office of Research and Development
Substance Related Disorders
Screening and Brief Advice to Reduce Teen Substance Use
The purpose of this study is to test the effectiveness of a brief intervention for alcohol and drug use in adolescents that a primary care doctor can give in his/her office.
- Trial name
- NCT00227877
- Testing
- cSBA - New England, USA, cSBA - Prague, CZR
- Where
- 6 sites in United States, Czechia
- Volunteers
- 2,695 people
- Sponsor
- Boston Children's Hospital
Alcohol Abuse, Criminalism
Survey of Adolescent Living in Vestmanland
The interaction of MAO-A genotype and psychosocial risk, in relation to male adolescent criminality The interaction of 5-HTTLPR genotype and psychosocial risk in relation to excessive adolescent alcohol consumption The…
- Conditions
- Alcohol Abuse, Criminalism, Depression
- Trial name
- SALVe (NCT01306812)
- Where
- Sweden
- Volunteers
- healthy volunteers welcome
- Sponsor
- Uppsala University
Alcohol Abuse
Emotion Regulation Interventions for Preventing Collegiate Escalations in Drinking
In the most recent National Survey on Drug Use and Health (NSDUH), college aged respondents between 18 and 25 years old reported the highest alcohol use rates (over 58%) as well as the highest rates of binge drinking of any age…
- Trial name
- PACER (NCT04492982)
- Testing
- Yoga, Distress Tolerance
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of Connecticut