Clinical trials: Aggression
Aggression
Virtual Reality Intervention (VR-GINSO) for Reducing Aggression in Young Offenders
The goal of this clinical trial is to see if a specific intervention program that uses virtual reality (VR) helps young people reduce aggressive behavior more than the same program without VR or their usual treatment.
- Trial name
- VR-GINSO (NCT07484919)
- Testing
- Virtual Reality, Active Control, Treatment as usual
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Universidad Francisco de Vitoria
Schizophrenia, Schizo Affective Disorder
Young Adults With Violent Behavior During Early Psychosis (Aim 2)
This study aims to provide an evidence-based behavioral intervention to reduce violent behavior for individuals experiencing early psychosis.
- Conditions
- Schizophrenia, Schizo Affective Disorder, Schizophreniform Disorders, Delusional Disorder
- Trial name
- NCT05756855
- Testing
- adapted behavioral intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Aggression, Adolescence
Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals
This study evaluates the effectiveness of a wise Intervention to reduce aggressive behaviors and promote prosocial behaviors toward LGB-TNB individuals among Spanish adolescents.
- Trial name
- LGB-TNB (NCT07212283)
- Testing
- Wise Intervention LGB-TNB, Values alignment wise intervention
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Child Behavior Problem, Disruptive Behavior
Pilot Study of Cognitive Behavior Therapy With Role-plays in Virtual Reality for Children With Behavior Problems
The main aim of this small pilot trial is to evaluate preliminary effects and feasibility of the child intervention YourSkills for child disruptive behavior (e.g., enhanced anger or aggressive behavior) when evaluated in Sweden…
- Conditions
- Child Behavior Problem, Disruptive Behavior, Oppositional Defiant Disorder, Conduct Problems
- Trial name
- NCT06559800
- Testing
- YourSkills: Cognitive behavioral therapy for children/youth with role-plays in virtual reality
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Child Behavior Problem, Disruptive Behavior
Pilot Study of Parent Training With Role-plays in Virtual Reality for Parents of Children With Behavior Problems
The main aim of this pilot trial is to evaluate preliminary effects and feasibility of a new parent training program for parents of children aged 8-16 years with disruptive behavior (e.g., angry, aggressive or defiant behavior).
- Conditions
- Child Behavior Problem, Disruptive Behavior, Oppositional Defiant Disorder, Conduct Problems
- Trial name
- NCT06559813
- Testing
- Step-by-step: A cognitive behavioral parent program with role-plays in virtual reality
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Karolinska Institutet
Autism, Intellectual Disabilities With Other Behavioral Symptoms
Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation
The goal of this study is to help children with autism and a co-occurring intellectual disability and their families learn practical strategies for managing issues like irritability, aggression, and other challenging behaviors.
- Conditions
- Autism, Intellectual Disabilities With Other Behavioral Symptoms, Intellectual Disability
- Trial name
- RT-ID (NCT07624448)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Prader-Willi Syndrome
Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation
The goal of this study is to help teens with Prader-Willi Syndrome (PWS) and their families learn practical strategies for managing issues like irritability, meltdowns, and anxiety.
- Trial name
- RT-PWS (NCT07607730)
- Testing
- Regulating Together group therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Mercy Hospital Kansas City
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Violence, Adolescent
Addressing Root Causes for Gun Violence Prevention (ARC-GVP)
The goal of this study is to help build the evidence base for a locally-relevant youth firearm violence prevention program in Washington D.C., a city experiencing disparities in youth firearm violence outcomes.
- Conditions
- Violence, Adolescent, Firearm Injury, Aggression
- Trial name
- NCT05887973
- Testing
- The T.R.I.G.G.E.R Project
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Agitation Management, Aggression
Effect of Verbal De-Escalation-Based Simulation on Agitation Management, Perception of Aggression, and Impact of Aggression in Emergency Department Nurses
This mixed-methods randomized controlled study aims to evaluate the effects of verbal de-escalation-based simulation training on emergency department nurses' knowledge of agitation management, perceptions of aggression, and the…
- Conditions
- Agitation Management, Aggression, Verbal De-Escalation
- Trial name
- NCT07784868
- Testing
- Standard Verbal De-Escalation Training, Verbal De-Escalation-Based Simulation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Violence Risk, Early Psychosis
BRAVE Program to Improve Safety and Reduce Violence Risk in Early Psychosis
This study evaluates the feasibility and acceptability of BRAVE, a manualized cognitive behavioral therapy (CBT)-based intervention designed to address dynamic risk factors for violence among young adults with early psychosis.
- Trial name
- BRAVE (NCT07417904)
- Testing
- BRAVE (Behavioral Response Against Violence Engagement), Treatment As Usual (TAU)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Howard University
Aggression Childhood, Bullying Victimization
Examining the Efficacy of the PRAISE With Coaching Program
The PReventing Aggression In Schools Everyday (PRAISE) Program has evidence of impact when run by research staff. PRAISE was adapted using community-based participatory research to a coaching model whereby school-staff are…
- Conditions
- Aggression Childhood, Bullying Victimization, Social Behavior
- Trial name
- NCT07191782
- Testing
- Universal, classroom-based, Bullying and Aggression Prevention Program
- Where
- United States
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Aggression, Self-injurious Behavior
Refinements of Functional Communication Training
Although treatments for problem behavior, like functional communication training (FCT), can be highly effective in the clinic, changes in the way the FCT is implemented (e.g., when transferring treatment to the home, when…
- Trial name
- NCT04045600
- Testing
- Trad FCT, Mult FCT, Mult FCT + Stimulus Fading
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder, Irritability
Behavior Therapy for Irritability in Autism
This is a clinical trial of a novel intervention, Behavioral Therapy for Irritability and Aggression (BTIA), for adolescents on the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Irritability, Disruptive Behavior, Anger
- Trial name
- BTIA (NCT04654260)
- Testing
- Behavioral Therapy for Irritability in Autism, Psychoeducation and Supportive Therapy (PST)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Yale University
Aggression
NIH R01 Friend to Friend With Coaching
This study examines the effectiveness of the Friend to Friend (F2F) program when conducted by teachers and counselors with active coaching from the research team.
- Trial name
- NCT04164472
- Testing
- Friend to Friend (F2F) with Coaching
- Where
- United States
- Volunteers
- 5,250 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Conduct Disorder, Antisocial Behavior
The Effectiveness of Forensic Outpatient Systemic Therapy: a Multiple Case Experimental Design
The purpose of this study is to investigate the effectiveness and mediators of Forensic Outpatient Systemic Therapy (FAST).
- Conditions
- Conduct Disorder, Antisocial Behavior, Aggression, Behavioral Disorder
- Trial name
- FAST (NCT06032520)
- Testing
- FAST
- Where
- 2 sites in Netherlands
- Volunteers
- 21 people
- Sponsor
- Utrecht University
Autism, Intellectual Disability
Cognitive-Behavioral Therapy for Irritability in Children With Autism Spectrum Disorder and Intellectual Disability
In addition to the core symptoms, children and adolescents with Autism Spectrum Disorder (ASD) often exhibit disruptive behavior problems including irritability, tantrums, noncompliance, and aggression.
- Trial name
- NCT02914951
- Testing
- Cognitive-Behavioral Therapy, Functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Problem Behavior, Aggression
Manualized Assessment and Treatment Model of Challenging Behavior
Despite decades of mounting single-case-design evidence for the efficacy of applied behavior analysis (ABA) and other approaches for the assessment and treatment of challenging behavior, an evidence-based comprehensive approach…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05928247
- Testing
- Functional Communication Training (FCT), Non-Contingent Reinforcement (NCR), Competing Items and Response Blocking
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Conduct Disorder, Mentalization Based Therapy
Using Mentalization Based Therapy to Support Children and Adolescents Referred to Specialist Mental Health Services in the NHS for Aggressive and/or Violent Behaviour
The MICA Study is a research project that has been designed to work out how helpful mentalisation based therapy is. This is a new type of support that helps young people make sense of their own behaviours and feelings, and those…
- Conditions
- Conduct Disorder, Mentalization Based Therapy, Violent Behavior, Aggressive Behaviour
- Trial name
- MICA (NCT07091721)
- Testing
- Mentalization based therapy (MBT), Support as usual
- Where
- 8 sites in United Kingdom
- Volunteers
- 632 people
- Sponsor
- Anna Freud
Stress Disorders, Post-Traumatic, Depression
Resettled Refugee Families for Healing
The goal of this type I hybrid effectiveness-implementation trial is to test a family strengthening (FS) model delivered through multiple family groups (MFG) combined with a virtual peer mentoring program called TeenAge Health…
- Conditions
- Stress Disorders, Post-Traumatic, Depression, Antisocial Personality Disorder, Anxiety
- Trial name
- RRF4H (NCT06176638)
- Testing
- RRF4H Combination Intervention
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine