Inguinal HerniaNCT07910240
Bassini Repair Versus Desarda Technique in Urgent Complicated Inguinal Hernia Repair
A study testing Bassini Inguinal Herniorrhaphy and Desarda Inguinal Hernia Repair in people with Inguinal Hernia and Incarcerated Inguinal Hernia, run by Assiut University.
Trial summary
Inguinal hernias occur when abdominal contents, such as intestine or fat, protrude through a weakness in the lower abdominal wall. While most hernia repairs are scheduled electively, some hernias present as urgent emergencies due to incarceration (the contents become trapped) or strangulation (the blood supply to the… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Inguinal Hernia, Incarcerated Inguinal Hernia, Strangulated Inguinal Hernia
- What is being tested?
- Bassini Inguinal Herniorrhaphy and Desarda Inguinal Hernia Repair
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 70 participants
- Where
- No sites listed yet
- Study dates
- Nov 2026to Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients aged 18 years and older
- Urgent presentation of complicated inguinal hernia (incarcerated or strangulated)
- American Society of Anesthesiologists (ASA) Physical Status Classification I, II, or III
- Provision of signed written informed consent
Who cannot join
- Age under 18 years
- Elective (non-urgent) inguinal hernia presentations
- Recurrent inguinal hernia (history of prior ipsilateral groin or inguinal surgery)
- Documented coagulopathy or long-term anticoagulation therapy that cannot be reversed preoperatively
- American Society of Anesthesiologists (ASA) Physical Status Classification IV or V
- Refusal to provide written informed consent
About this study
Official title: Bassini Repair Versus Desarda Technique in Urgent Complicated Inguinal Hernia Repair: A Prospective Randomized Controlled Study
Inguinal hernias occur when abdominal contents, such as intestine or fat, protrude through a weakness in the lower abdominal wall. While most hernia repairs are scheduled electively, some hernias present as urgent emergencies due to incarceration (the contents become trapped) or strangulation (the blood supply to the trapped tissue is cut off). In emergency operations, synthetic mesh placement may be avoided due to the increased risk of surgical site infections, tissue swelling, or bowel contamination. In such settings, surgeons rely on tissue-based (mesh-free) repairs. The conventional Bassini repair is a standard non-mesh technique, but it can be associated with higher hernia recurrence rates. The Desarda technique is a physiological, mesh-free repair that uses an undetached strip of the patient's own external oblique aponeurosis (tendinous muscle tissue) to reinforce the weakened inguinal floor without tension.
The main objective of this study is to compare the surgical outcomes of conventional Bassini repair alone versus Bassini repair combined with the Desarda technique in adult patients undergoing emergency surgery for urgent, complicated inguinal hernias.
Read more
This prospective randomized controlled trial is conducted at the Department of General Surgery, Assiut University Hospital. A total of 70 eligible participants presenting with acutely complicated inguinal hernias will be randomly assigned to one of two equal groups:
- Group A (Bassini Repair): Patients undergo standard open emergency tissue herniorrhaphy alone.
- Group B (Desarda Repair): Patients undergo emergency herniorrhaphy combined with the Desarda aponeurotic reinforcement technique.
Participants are monitored during their hospital stay and will attend structured outpatient follow-up visits up to 12 months postoperatively. The primary outcome evaluated is the rate of hernia recurrence. Secondary outcomes include surgical site infections, seroma and hematoma formation, postoperative pain scores (using the Visual Analogue Scale), duration of operative procedure, hospital stay length, and time required to resume normal activities and return to work.
- Being tested
- Bassini Inguinal Herniorrhaphy, Desarda Inguinal Hernia Repair
- Keywords
- Bassini repair, Desarda technique, Emergency hernia repair, Complicated inguinal hernia, Tissue-based repair, Non-mesh repair, Herniorrhaphy
- Medical subject headings
- Hernia, Inguinal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Bassini Inguinal HerniorrhaphyProcedure or surgery
Standard open tissue-based repair performed without prosthetic mesh. Through a transverse groin incision, the hernia sac is dissected, contents reduced (non-viable bowel resected with primary anastomosis), and high transfixion ligation completed at the deep ring with a 2-0 polypropylene suture. Posterior inguinal canal wall reconstruction is achieved by placing interrupted 0-polypropylene sutures approximating the conjoint tendon (inguinal falx) to the shelving edge of the inguinal ligament from the pubic tubercle to the deep ring. The external oblique aponeurosis is then closed over the spermatic cord using 2-0 polyglactin.
Desarda Inguinal Hernia RepairProcedure or surgery
Open tissue-based repair reinforcing the posterior inguinal canal wall using an autologous aponeurotic strip without prosthetic mesh. Following standard sac dissection, content reduction, and high ligation, a rectangular strip measuring 2-3 cm wide and 7-9 cm long is created from the lower leaf of the external oblique aponeurosis (EOA), remaining attached laterally near the deep ring. The medial free end is sutured to the conjoint tendon at the pubic tubercle, and the inferior border is sutured to the inguinal ligament using interrupted 0-polypropylene sutures. The upper leaf of the EOA is then sutured to the superior margin of the strip with 2-0 polyglactin.
| Study group | Role | What they receive |
|---|---|---|
| Group A: Bassini Repair (Herniorrhaphy Alone) | Active comparator | Patients undergo open emergency inguinal hernia repair via a transverse groin incision. The hernia sac is dissected, contents reduced (with bowel resection and primary anastomosis performed if non-viable), and high ligation performed at the deep ring using a 2-0 polypropylene suture. Posterior inguinal canal wall repair is performed using the Bassini technique: interrupted 0-polypropylene sutures approximate the conjoint tendon (inguinal falx) to the shelving edge of the inguinal ligament from the pubic tubercle to the deep inguinal ring without prosthetic mesh. The external oblique aponeurosis is closed over the cord using 2-0 polyglactin. Receives: Procedure: Bassini Inguinal Herniorrhaphy |
| Group B: Herniorrhaphy Combined with Desarda Technique | Experimental | Patients undergo open emergency repair with identical initial access, sac reduction, and high ligation as Group A. Following high ligation, a 2-3 cm wide by 7-9 cm long strip is fashioned from the lower leaf of the external oblique aponeurosis (EOA), left undetached laterally near the deep ring. The medial free end is sutured to the conjoint tendon at the pubic tubercle with interrupted 0-polypropylene sutures, and the inferior border is sutured to the shelving edge of the inguinal ligament up to the deep ring. The upper leaf of the EOA is sutured to the superior edge of the strip with 2-0 polyglactin, providing a physiological, tension-free posterior wall repair without prosthetic mesh. Receives: Procedure: Desarda Inguinal Hernia Repair |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of Inguinal Hernia Recurrence
Defined as the presence of any clinically detectable protrusion or bulge in the ipsilateral groin or inguinal region on physical examination, confirmed objectively by high-resolution inguinal ultrasonography.
Measured: 12 months postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Nov 2026
- Study startNov 2026 (estimated)
- Primary completionNov 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Inguinal HerniaStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 70 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hossam Mamdouh Mohamed Abdellatif, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07910240
- Sponsor's protocol ID
- Bassini vs. Desarda for Hernia
- Status last verified
- Oct 2026
- First submitted
- 27 Oct 2026
- Last updated
- 2 Nov 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Bassini Repair Versus Desarda Technique in Urgent Complicated Inguinal Hernia Repair: A Prospective Randomized Controlled Study
- ClinicalTrials.gov ID
- NCT07910240
- Acronym / sponsor ID
- Bassini vs. Desarda for Hernia
- Keywords
- Bassini repair, Desarda technique, Emergency hernia repair, Complicated inguinal hernia, Tissue-based repair, Non-mesh repair, Herniorrhaphy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 70 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- Nov 2026 (estimated)
- Primary completion
- Nov 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 2 Nov 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Inguinal hernias occur when abdominal contents, such as intestine or fat, protrude through a weakness in the lower abdominal wall. While most hernia repairs are scheduled electively, some hernias present as urgent emergencies due to incarceration (the contents become trapped) or strangulation (the blood supply to the trapped tissue is cut off). In emergency operations, synthetic mesh placement may be avoided due to the increased risk of surgical site infections, tissue swelling, or bowel contamination. In such settings, surgeons rely on tissue-based (mesh-free) repairs. The conventional Bassini repair is a standard non-mesh technique, but it can be associated with higher hernia recurrence rates. The Desarda technique is a physiological, mesh-free repair that uses an undetached strip of the patient's own external oblique aponeurosis (tendinous muscle tissue) to reinforce the weakened inguinal floor without tension.
The main objective of this study is to compare the surgical outcomes of conventional Bassini repair alone versus Bassini repair combined with the Desarda technique in adult patients undergoing emergency surgery for urgent, complicated inguinal hernias.
This prospective randomized controlled trial is conducted at the Department of General Surgery, Assiut University Hospital. A total of 70 eligible participants presenting with acutely complicated inguinal hernias will be randomly assigned to one of two equal groups:
- Group A (Bassini Repair): Patients undergo standard open emergency tissue herniorrhaphy alone.
- Group B (Desarda Repair): Patients undergo emergency herniorrhaphy combined with the Desarda aponeurotic reinforcement technique.
Participants are monitored during their hospital stay and will attend structured outpatient follow-up visits up to 12 months postoperatively. The primary outcome evaluated is the rate of hernia recurrence. Secondary outcomes include surgical site infections, seroma and hematoma formation, postoperative pain scores (using the Visual Analogue Scale), duration of operative procedure, hospital stay length, and time required to resume normal activities and return to work.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A: Bassini Repair (Herniorrhaphy Alone) | Active comparator | Procedure: Bassini Inguinal HerniorrhaphyPatients undergo open emergency inguinal hernia repair via a transverse groin incision. The hernia sac is dissected, contents reduced (with bowel resection and primary anastomosis performed if non-viable), and high ligation performed at the deep ring using a 2-0 polypropylene suture. Posterior inguinal canal wall repair is performed using the Bassini technique: interrupted 0-polypropylene sutures approximate the conjoint tendon (inguinal falx) to the shelving edge of the inguinal ligament from the pubic tubercle to the deep inguinal ring without prosthetic mesh. The external oblique aponeurosis is closed over the cord using 2-0 polyglactin. |
| Group B: Herniorrhaphy Combined with Desarda Technique | Experimental | Procedure: Desarda Inguinal Hernia RepairPatients undergo open emergency repair with identical initial access, sac reduction, and high ligation as Group A. Following high ligation, a 2-3 cm wide by 7-9 cm long strip is fashioned from the lower leaf of the external oblique aponeurosis (EOA), left undetached laterally near the deep ring. The medial free end is sutured to the conjoint tendon at the pubic tubercle with interrupted 0-polypropylene sutures, and the inferior border is sutured to the shelving edge of the inguinal ligament up to the deep ring. The upper leaf of the EOA is sutured to the superior edge of the strip with 2-0 polyglactin, providing a physiological, tension-free posterior wall repair without prosthetic mesh. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients aged 18 years and older
- Urgent presentation of complicated inguinal hernia (incarcerated or strangulated)
- American Society of Anesthesiologists (ASA) Physical Status Classification I, II, or III
- Provision of signed written informed consent
Key exclusion criteria (6 listed)
- Age under 18 years
- Elective (non-urgent) inguinal hernia presentations
- Recurrent inguinal hernia (history of prior ipsilateral groin or inguinal surgery)
- Documented coagulopathy or long-term anticoagulation therapy that cannot be reversed preoperatively
- American Society of Anesthesiologists (ASA) Physical Status Classification IV or V
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Bassini Inguinal HerniorrhaphyStandard open tissue-based repair performed without prosthetic mesh. Through a transverse groin incision, the hernia sac is dissected, contents reduced (non-viable bowel resected with primary anastomosis), and high transfixion ligation completed at the deep ring with a 2-0 polypropylene suture. Posterior inguinal canal wall reconstruction is achieved by placing interrupted 0-polypropylene sutures approximating the conjoint tendon (inguinal falx) to the shelving edge of the inguinal ligament from the pubic tubercle to the deep ring. The external oblique aponeurosis is then closed over the spermatic cord using 2-0 polyglactin. | Procedure or surgery | Group A: Bassini Repair (Herniorrhaphy Alone) |
| Desarda Inguinal Hernia RepairOpen tissue-based repair reinforcing the posterior inguinal canal wall using an autologous aponeurotic strip without prosthetic mesh. Following standard sac dissection, content reduction, and high ligation, a rectangular strip measuring 2-3 cm wide and 7-9 cm long is created from the lower leaf of the external oblique aponeurosis (EOA), remaining attached laterally near the deep ring. The medial free end is sutured to the conjoint tendon at the pubic tubercle, and the inferior border is sutured to the inguinal ligament using interrupted 0-polypropylene sutures. The upper leaf of the EOA is then sutured to the superior margin of the strip with 2-0 polyglactin. | Procedure or surgery | Group B: Herniorrhaphy Combined with Desarda Technique |
Primary outcome
Incidence of Inguinal Hernia Recurrence
Time frame: 12 months postoperatively
Defined as the presence of any clinically detectable protrusion or bulge in the ipsilateral groin or inguinal region on physical examination, confirmed objectively by high-resolution inguinal ultrasonography.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Nov 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Bassini Inguinal Herniorrhaphy and Desarda Inguinal Hernia Repair in people with Inguinal Hernia and Incarcerated Inguinal Hernia, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 2 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of Inguinal Hernia Recurrence (time frame: 12 months postoperatively). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Nov 2026.