Relieves Vaginal Dryness / Improves Self-LubricationNCT07893795
A Clinical Trial to Evaluate the Effects of the NeuEve Dryness Treatment Kit on Vaginal Health, Comfort, and Quality of Life in Postmenopausal Women
A study testing Intervention in people with Relieves Vaginal Dryness / Improves Self-Lubrication and Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin), run by NeuEve at 1 site in United States.
Trial summary
This is a decentralized, single-group, open-label clinical trial evaluating a 12-week regimen of the NeuEve Dryness Treatment Kit (comprising Feminine Moisture Support oral softgels, Bone Support oral capsules, NeuEve Salve vulvar topical cream, NeuEve vaginal suppositories, and NeuEve Multivitamin) in postmenopausal… Read more about this study
- Who is it for?
- Ages 55 to 65 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Relieves Vaginal Dryness / Improves Self-Lubrication, Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin), Improves Vaginal Wall Thickness
- What is being tested?
- Intervention
- Type of treatment
- Pill or oral medicine
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- Sep 2026to Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 to 65 years
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
None listed.
Who cannot join
- Female, aged 55-65 years at the time of consent. Postmenopausal (defined as ≥12 consecutive months without menstrual bleeding, or surgical menopause). Currently experiencing self-reported vaginal dryness, painful sex (dyspareunia), and vaginal itching. Willing and able to use all five products of the NeuEve Dryness Treatment Kit as directed for 12 weeks. Willing to perform at-home vaginal pH testing and at-home vaginal microbiome sample collection. Willing to maintain current diet, sleep schedule, and physical activity level for the duration of the 12-week study. Willing to complete all study questionnaires via the Citruslabs platform. Resides in the United States with a deliverable shipping address.
- Known allergy or hypersensitivity to any ingredient in any component of the NeuEve Dryness Treatment Kit (including palm/coconut oil, beeswax, sea buckthorn, evening primrose, botanical extracts, or essential oils listed in the formulations). Currently pregnant, breastfeeding, or planning pregnancy during the study period. Self-reported diagnosed with or treated for a sexually transmitted infection (STI), pelvic inflammatory disease (PID), or a vaginal or urinary tract infection within the past 30 days. Current use of systemic or vaginal estrogen therapy, vaginal DHEA, or any other prescription treatment for vaginal dryness/GSM, unless on a stable regimen for ≥3 months and willing to maintain it without changes during the study (use of competing topical/vaginal moisturizers, lubricants, or suppositories during the study period is not permitted). History of gynecologic cancer (cervical, vaginal, vulvar, endometrial, or ovarian) within the past 2 years, or current active malignancy. Current participation in another interventional clinical study. Any medical condition that, in the opinion of the investigator, would compromise participant safety or the integrity of the study data. Planning to travel outside of the United States during the study duration.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
This is a decentralized, single-group, open-label clinical trial evaluating a 12-week regimen of the NeuEve Dryness Treatment Kit (comprising Feminine Moisture Support oral softgels, Bone Support oral capsules, NeuEve Salve vulvar topical cream, NeuEve vaginal suppositories, and NeuEve Multivitamin) in postmenopausal women aged 55-65 who experience vaginal dryness, painful sex, and vaginal itching. The study aims to evaluate the effect of the kit on vaginal symptoms, vaginal pH, vaginal microbiome composition, sexual function, and quality of life over 12 weeks of use.
- Conditions
- Relieves Vaginal Dryness / Improves Self-Lubrication, Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin), Improves Vaginal Wall Thickness, Reduces Pain During Sex, Reduces Vaginal Odor, Improves Vaginal Microbiome i.e. Increases Lactobacilli
- Being tested
- Intervention
- Medical subject headings
- Aortic Stenosis, Supravalvular, Orgasm
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
InterventionDietary supplement
All participants receive the five-component NeuEve Dryness Treatment Kit for 12 weeks: Feminine Moisture Support (1 softgel orally twice daily with meals); Bone Support (1 capsule orally twice daily with meals); NeuEve Salve (dime-sized amount applied topically to the vulva once daily at bedtime); NeuEve Silk Suppository (1 suppository inserted vaginally every other day at bedtime for Weeks 1-4) transitioning to NeuEve Silver Suppository (1 suppository inserted vaginally every 5 days for Weeks 5-12); and NeuEve Multivitamin (3 capsules daily with food, divided equally across the day).
| Study group | Role | What they receive |
|---|---|---|
| NeuEve Dryness Treatment Ki | Experimental | Not described Receives: Dietary Supplement: Intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Vaginal Dryness
Change from Baseline to Week 12 in self-reported vaginal dryness assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
Measured: Baseline to Week 12
Change in Vaginal Itching
Change from Baseline to Week 12 in self-reported vaginal itching assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
Measured: Baseline to Week 12
Change in Vaginal Burning
Change from Baseline to Week 12 in self-reported vaginal burning assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
Measured: Baseline to Week 12
Secondary outcomes (2)
Change in Painful Sex (Dyspareunia)
Change from Baseline to Week 12 in self-reported painful sex assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
Measured: Baseline to Week 12
Change in Vaginal pH
Change from Baseline to Week 12 in vaginal pH measured by at-home vaginal pH test strips (self-administered)
Measured: Baseline, Week 4, Week 8, and Week 12
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Oct 2026
- Study startSep 2026 (estimated)
- Primary completionDec 2026 (estimated)
- Study completionDec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Relieves Vaginal Dryness / Improves Self-LubricationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- NeuEve
- Sponsor type
- Industry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07893795
- Sponsor's protocol ID
- NEUEV-38977
- Status last verified
- Aug 2026
- First submitted
- 19 Oct 2026
- Last updated
- 26 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 26 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Clinical Trial to Evaluate the Effects of the NeuEve Dryness Treatment Kit on Vaginal Health, Comfort, and Quality of Life in Postmenopausal Women
- ClinicalTrials.gov ID
- NCT07893795
- Acronym / sponsor ID
- NEUEV-38977
- Conditions
- Relieves Vaginal Dryness / Improves Self-Lubrication, Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin), Improves Vaginal Wall Thickness, Reduces Pain During Sex, Reduces Vaginal Odor, Improves Vaginal Microbiome i.e. Increases Lactobacilli
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- NeuEveIndustry (pharma, biotech, devices)
- Collaborators
- Citruslabs
- Study start
- Sep 2026 (estimated)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- Dec 2026 (estimated)
- First posted
- 26 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This is a decentralized, single-group, open-label clinical trial evaluating a 12-week regimen of the NeuEve Dryness Treatment Kit (comprising Feminine Moisture Support oral softgels, Bone Support oral capsules, NeuEve Salve vulvar topical cream, NeuEve vaginal suppositories, and NeuEve Multivitamin) in postmenopausal women aged 55-65 who experience vaginal dryness, painful sex, and vaginal itching. The study aims to evaluate the effect of the kit on vaginal symptoms, vaginal pH, vaginal microbiome composition, sexual function, and quality of life over 12 weeks of use.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| NeuEve Dryness Treatment Ki | Experimental | Dietary Supplement: Intervention |
Who may qualify
- Ages
- 55 to 65 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (0 listed)
Key exclusion criteria (2 listed)
- Female, aged 55-65 years at the time of consent. Postmenopausal (defined as ≥12 consecutive months without menstrual bleeding, or surgical menopause). Currently experiencing self-reported vaginal dryness, painful sex (dyspareunia), and vaginal itching. Willing and able to use all five products of the NeuEve Dryness Treatment Kit as directed for 12 weeks. Willing to perform at-home vaginal pH testing and at-home vaginal microbiome sample collection. Willing to maintain current diet, sleep schedule, and physical activity level for the duration of the 12-week study. Willing to complete all study questionnaires via the Citruslabs platform. Resides in the United States with a deliverable shipping address.
- Known allergy or hypersensitivity to any ingredient in any component of the NeuEve Dryness Treatment Kit (including palm/coconut oil, beeswax, sea buckthorn, evening primrose, botanical extracts, or essential oils listed in the formulations). Currently pregnant, breastfeeding, or planning pregnancy during the study period. Self-reported diagnosed with or treated for a sexually transmitted infection (STI), pelvic inflammatory disease (PID), or a vaginal or urinary tract infection within the past 30 days. Current use of systemic or vaginal estrogen therapy, vaginal DHEA, or any other prescription treatment for vaginal dryness/GSM, unless on a stable regimen for ≥3 months and willing to maintain it without changes during the study (use of competing topical/vaginal moisturizers, lubricants, or suppositories during the study period is not permitted). History of gynecologic cancer (cervical, vaginal, vulvar, endometrial, or ovarian) within the past 2 years, or current active malignancy. Current participation in another interventional clinical study. Any medical condition that, in the opinion of the investigator, would compromise participant safety or the integrity of the study data. Planning to travel outside of the United States during the study duration.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| InterventionAll participants receive the five-component NeuEve Dryness Treatment Kit for 12 weeks: Feminine Moisture Support (1 softgel orally twice daily with meals); Bone Support (1 capsule orally twice daily with meals); NeuEve Salve (dime-sized amount applied topically to the vulva once daily at bedtime); NeuEve Silk Suppository (1 suppository inserted vaginally every other day at bedtime for Weeks 1-4) transitioning to NeuEve Silver Suppository (1 suppository inserted vaginally every 5 days for Weeks 5-12); and NeuEve Multivitamin (3 capsules daily with food, divided equally across the day). | Dietary supplement | NeuEve Dryness Treatment Ki |
Primary outcome
Change in Vaginal Dryness
Time frame: Baseline to Week 12
Change from Baseline to Week 12 in self-reported vaginal dryness assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
Change in Vaginal Itching
Time frame: Baseline to Week 12
Change from Baseline to Week 12 in self-reported vaginal itching assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
Change in Vaginal Burning
Time frame: Baseline to Week 12
Change from Baseline to Week 12 in self-reported vaginal burning assessed via a study-specific vaginal symptom questionnaire administered through the Citruslabs platform
2 secondary outcomes
Change in Painful Sex (Dyspareunia)
Time frame: Baseline to Week 12
Change in Vaginal pH
Time frame: Baseline, Week 4, Week 8, and Week 12
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Oct 2026.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Intervention in people with Relieves Vaginal Dryness / Improves Self-Lubrication and Improves Strength & Elasticity of Vagina (Aka Collagen and Elastin), run by NeuEve at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 26 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Patrick Renner (42424250284, hello@citruslabs.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Vaginal Dryness (time frame: Baseline to Week 12). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Oct 2026.