StrokeNCT07887360
Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors
A study testing Lower Limb PNF Combined with Core Stability Training and Lower Limb PNF alone in people with Stroke, run by Ibadat International University, Islamabad at 1 site in Pakistan.
Trial summary
This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors. Read more about this study
- Who is it for?
- Ages 40 years and older
- Conditions the study is for
- Stroke
- What is being tested?
- Lower Limb PNF Combined with Core Stability Training and Lower Limb PNF alone
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 sitePakistan
- Study dates
- 25 Jul 2026to 30 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥ 40 years Male and female participants. Clinically diagnosed chronic stroke (>6 months post-onset). Impaired dynamic balance or mobility. Ability to follow simple verbal instructions and medically stable.
Who cannot join
- Severe cognitive impairment preventing participation. Severe spasticity (Modified Ashworth Scale >3). Other neurological or musculoskeletal conditions affecting balance. Uncontrolled cardiovascular conditions.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Stroke support foundation
Mingora, KPK, 19130
Physical therapist, 923463234458, behlol109@gmail.com
Somiya Naz, BSPT, PPDPT, PhD Scholar, 923315163093, dr.somiyanaz@gmail.com
About this study
This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors. The study aims to determine whether adding core stability training produces greater improvements in dynamic balance and functional mobility.
Read the detailed description
Participants will be allocated to two groups. Group A will receive supervised lower limb PNF combined with core stability exercises 5 times per week for 6 weeks, with each session lasting 30-35 minutes. Group B will receive supervised lower limb PNF alone with the same frequency and duration. PNF will include diagonal and spiral lower-limb patterns (D1 and D2 flexion-extension), with functional PNF patterns and rhythmic stabilization as described in the protocol. The combined group will additionally perform core exercises including bridging, planks, Swiss-ball activities, and core integration tasks. Outcomes will be assessed at baseline and after 6 weeks using the Timed Up and Go (TUG) test and 10-Meter Walk Test (10MWT).
- Conditions
- Stroke
- Being tested
- Lower Limb PNF Combined with Core Stability Training, Lower Limb PNF alone
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Lower Limb PNF Combined with Core Stability TrainingOther
Lower limb PNF (D1/D2 diagonal and spiral patterns, rhythmic stabilization, functional PNF patterns) plus core stability exercises including bridging, planks, Swiss-ball activities and core integration; 5 times/week for 6 weeks; 30-35 minutes/session
Lower Limb PNF aloneOther
Lower limb PNF using D1/D2 diagonal and spiral patterns, rhythmic stabilization and functional PNF patterns without added core stability exercises; 5 times/week for 6 weeks; 30-35 minutes/session.
| Study group | Role | What they receive |
|---|---|---|
| Lower Limb PNF Combined with Core Stability Training | Experimental | Lower limb PNF (D1/D2 diagonal and spiral patterns, rhythmic stabilization, functional PNF patterns) plus core stability exercises including bridging, planks, Swiss-ball activities and core integration; 5 times/week for 6 weeks; 30-35 minutes/session. Receives: Other: Lower Limb PNF Combined with Core Stability Training |
| Lower Limb PNF alone | Active comparator | Lower limb PNF using D1/D2 diagonal and spiral patterns, rhythmic stabilization and functional PNF patterns without added core stability exercises; 5 times/week for 6 weeks; 30-35 minutes/session. Receives: Other: Lower Limb PNF alone |
What is being measured
The primary outcome is the main question the study is designed to answer.
Timed Up and Go (TUG) Test
The Timed Up and Go (TUG) Test is a reliable clinical test used to assess functional mobility, dynamic balance, walking ability, and risk of falls. A reduction in completion time generally indicates improved functional mobility
Measured: baseline and after 6 weeks of intervention.
10-Meter Walk Test (10MWT)
The 10-Meter Walk Test (10MWT) is a standardized clinical assessment used to measure walking speed (gait speed) in metres per second (m/s). Increased walking speed generally indicates improved walking performance.
Measured: baseline and after 6 weeks of intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Oct 2026
- Study start25 Jul 2026
- Primary completion25 Dec 2026 (estimated)
- Study completion30 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ibadat International University, Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Somiya Naz, Ibadat International University, Islamabad
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07887360
- Sponsor's protocol ID
- IIUI/RERC/ADT/2026/07/378
- Status last verified
- Oct 2026
- First submitted
- 14 Oct 2026
- Last updated
- 21 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Lower Limb Proprioceptive Neuromuscular Facilitation Combined With Core Stability Training Versus Proprioceptive Neuromuscular Facilitation Alone on Balance and Functional Mobility in Chronic Stroke Survivors
- ClinicalTrials.gov ID
- NCT07887360
- Acronym / sponsor ID
- IIUI/RERC/ADT/2026/07/378
- Conditions
- Stroke
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Ibadat International University, IslamabadUniversity, hospital or other
- Study start
- 25 Jul 2026 (actual)
- Primary completion
- 25 Dec 2026 (estimated)
- Study completion
- 30 Dec 2026 (estimated)
- First posted
- 21 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial compares lower limb proprioceptive neuromuscular facilitation (PNF) combined with core stability training versus lower limb PNF alone in chronic stroke survivors. The study aims to determine whether adding core stability training produces greater improvements in dynamic balance and functional mobility.
Detailed description
Participants will be allocated to two groups. Group A will receive supervised lower limb PNF combined with core stability exercises 5 times per week for 6 weeks, with each session lasting 30-35 minutes. Group B will receive supervised lower limb PNF alone with the same frequency and duration. PNF will include diagonal and spiral lower-limb patterns (D1 and D2 flexion-extension), with functional PNF patterns and rhythmic stabilization as described in the protocol. The combined group will additionally perform core exercises including bridging, planks, Swiss-ball activities, and core integration tasks. Outcomes will be assessed at baseline and after 6 weeks using the Timed Up and Go (TUG) test and 10-Meter Walk Test (10MWT).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Lower Limb PNF Combined with Core Stability Training | Experimental | Other: Lower Limb PNF Combined with Core Stability TrainingLower limb PNF (D1/D2 diagonal and spiral patterns, rhythmic stabilization, functional PNF patterns) plus core stability exercises including bridging, planks, Swiss-ball activities and core integration; 5 times/week for 6 weeks; 30-35 minutes/session. |
| Lower Limb PNF alone | Active comparator | Other: Lower Limb PNF aloneLower limb PNF using D1/D2 diagonal and spiral patterns, rhythmic stabilization and functional PNF patterns without added core stability exercises; 5 times/week for 6 weeks; 30-35 minutes/session. |
Who may qualify
- Ages
- 40 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Age ≥ 40 years Male and female participants. Clinically diagnosed chronic stroke (>6 months post-onset). Impaired dynamic balance or mobility. Ability to follow simple verbal instructions and medically stable.
Key exclusion criteria (1 listed)
- Severe cognitive impairment preventing participation. Severe spasticity (Modified Ashworth Scale >3). Other neurological or musculoskeletal conditions affecting balance. Uncontrolled cardiovascular conditions.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Lower Limb PNF Combined with Core Stability TrainingLower limb PNF (D1/D2 diagonal and spiral patterns, rhythmic stabilization, functional PNF patterns) plus core stability exercises including bridging, planks, Swiss-ball activities and core integration; 5 times/week for 6 weeks; 30-35 minutes/session | Other | Lower Limb PNF Combined with Core Stability Training |
| Lower Limb PNF aloneLower limb PNF using D1/D2 diagonal and spiral patterns, rhythmic stabilization and functional PNF patterns without added core stability exercises; 5 times/week for 6 weeks; 30-35 minutes/session. | Other | Lower Limb PNF alone |
Primary outcome
Timed Up and Go (TUG) Test
Time frame: baseline and after 6 weeks of intervention.
The Timed Up and Go (TUG) Test is a reliable clinical test used to assess functional mobility, dynamic balance, walking ability, and risk of falls. A reduction in completion time generally indicates improved functional mobility
10-Meter Walk Test (10MWT)
Time frame: baseline and after 6 weeks of intervention.
The 10-Meter Walk Test (10MWT) is a standardized clinical assessment used to measure walking speed (gait speed) in metres per second (m/s). Increased walking speed generally indicates improved walking performance.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Oct 2026.
- Individual participant dataSharing planned: No
Related trials for Stroke
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Temporal Interference Stimulation for Upper-Limb Motor Recovery in Early Subacute Stroke
Acute Ischemic Stroke
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ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
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Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
Acute Ischemic Stroke, Basilar Artery Occlusion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Lower Limb PNF Combined with Core Stability Training and Lower Limb PNF alone in people with Stroke, run by Ibadat International University, Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 21 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Physical therapist (923415026592, behlol109@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Timed Up and Go (TUG) Test (time frame: baseline and after 6 weeks of intervention.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Oct 2026.