Ulnar Nerve TranspositionNCT07880470

Is Splinting After Ulnar Nerve Transposition Necessary?

A study testing Stiff splint and No splint in people with Ulnar Nerve Transposition, run by University of Chicago at 5 sites in United States.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Sites and contacts

Official record

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Trial summary

The goal of this clinical trial is to learn whether patient recovery after ulnar nerve transposition (UNT) requires a splint. The main questions it aims to answer are: Does the effect that early versus delayed mobilization after UNT have on patient sleep quality differ? What are the medical complications… Read more about this study

Who is it for?: Ages 18 years and older
Conditions the study is for: Ulnar Nerve Transposition
What is being tested?: Stiff splint and No splint
Type of treatment: Surgery or procedure
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 50 participants
Where: 5 sitesUnited States
Study dates: Oct 2026to Feb 2028
Phase: Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 years and older
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Over 18 years old
Indicated for Ulnar Nerve Transposition
Able and willing to complete online questionnaires
Able and willing to provide written informed consent

Who cannot join

Additional procedures to be performed on ipsilateral or contralateral extremity

Trial locations and contacts

5 sites in 1 country. Contact the study team or a site near you to ask about taking part.

City, postcode or hospital

5 sites in 1 country

United States5 sites

UChicago Medicine at Ingalls - Calumet City
Calumet City, Illinois, 60409
Daniel Hong, MD, 773-906-4605, daniel.hong@bsd.uchicago.edu
UChicago Medicine Crown Point
Crown Point, Indiana, 46307
Daniel Hong, MD, 773-906-4605, daniel.hong@bsd.uchicago.edu
University of Chicago Medical Center
Hyde Park, Illinois, 60637
Daniel Hong, MD, 773-906-4605, daniel.hong@bsd.uchicago.edu
Daniel Y Hong, MD
UChicago Medicine Orland Park
Orland Park, Illinois, 60462
Daniel Hong, MD, 773-906-4605, daniel.hong@bsd.uchicago.edu
UChicago Medicine at Ingalls - Tinley Park
Tinley Park, Illinois, 60477
Daniel Hong, MD, 773-906-4605, daniel.hong@bsd.uchicago.edu

Other trials in United States

About this study

The goal of this clinical trial is to learn whether patient recovery after ulnar nerve transposition (UNT) requires a splint. The main questions it aims to answer are:

Does the effect that early versus delayed mobilization after UNT have on patient sleep quality differ?
What are the medical complications, reoperations, and timeline of returning to work that result from this procedure like?

Participants will be placed in a stiff splint (that limits elbow movement) or no splint (that allows for earlier elbow movement) after this surgery. Participants will report their recovery through surveys measuring physical function, pain, and sleep. Researchers will compare the results between the two types of splinting.

Conditions: Ulnar Nerve Transposition
Being tested: Stiff splint, No splint
Keywords: Ulnar nerve transposition, Splinting

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Stiff splintProcedure or surgery
Participants receive a stiff splint that limits elbow movement
No splintProcedure or surgery
Participants receive a soft dressing that allows for movement.

Study groups in NCT07880470
Study group	Role	What they receive
Stiff Splint	Active comparator	Participants receive a stiff splint that limits elbow movement Receives: Procedure: Stiff splint
No splint	Active comparator	Participants receive a soft dressing that allows for movement. Receives: Procedure: No splint

What is being measured

The primary outcome is the main question the study is designed to answer.

Pittsburg Sleep Quality Index scores
A survey that measures self reported sleep measures from a score of 0 to 21 and a score over 5 indicates sleep difficulties and poor sleep quality.
Measured: 2 weeks, 6 weeks, 3 months, 6 months, 1 year

Secondary outcomes (4)

Patient Reported Outcome Measures Information System (PROMIS)
The PROMIS physical function instrument measures self reported capability for daily physical activities and is scored on standardized norm-based-T-score where higher scores indicate greater physical capacity and functioning. The PROMIS upper extremity instrument measures physical capability related to the hand, wrist, arm and shoulder. Responses are scored on a standardized norm-based-T-score where higher scores indicate better function. The PROMIS Pain Interference instrument measures daily pain levels and how they interrupt daily function. Responses are scored on a standardized norm-based-T-score where higher scores indicate greater pain interference.
Measured: 2 weeks, 6 weeks, 3 months, 6 months, 1 year
Average Patient-Reported Activity Level and Recovery Satisfaction
Measures how quickly the participant returns to normal function in daily life and activity in weeks. Each questionnaire has two scales that are asked at each time point up to one year post-surgery. One asks about current activity level compared to pre-surgery on a scale of 1-10 with 1 being significantly less active and 10 being significantly more active. The other asks about satisfaction with the recovery process on a scale of 1-10 with 1 being very dissatisfied and 10 being very satisfied.
Measured: 2 weeks, 6 weeks, 3 months, 6 months, 1 year
Number of Patients with Post operative complications
Includes rates of complications (wound dehiscence, recurrent nerve instability, hematoma formation) and reoperation measured by yes or no question at each timepoint.
Measured: 2 weeks, 6 weeks, 3 months, 6 months, 1 year
Change in Degrees of Elbow Range of Motion
Measures the change in elbow flexion after the procedure compared to the pre-operative baseline. The evaluation is performed during the standard clinical exam with a continuous scale of 0-145 degrees with a larger degree of flexion indicating better recovery and joint mobility.
Measured: 2 weeks, 6 weeks, 3 months, 6 months, 1 year

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

Oct 2026Feb 2028

First posted19 Oct 2026
Study startOct 2026 (estimated)
Primary completionFeb 2028 (estimated)
Study completionFeb 2028 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Ulnar Nerve TranspositionStudies of the same condition, open and under way.
More trials run by University of ChicagoThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Supportive care
Allocation: Randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 50 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07880470
Sponsor's protocol ID: IRB26-0352
Status last verified: Oct 2026
First submitted: 12 Oct 2026
Last updated: 22 Oct 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No: There is not a plan to make IPD available.