Postmenopausal OsteoporosisNCT07875894
Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis
A study testing Sensorimotor-Based Balance Training and Digitally Augmented Core Stabilization in people with Postmenopausal Osteoporosis, run by Riphah International University at 1 site in Pakistan.
Trial summary
This randomized controlled trial aims to compare the effects of sensorimotor-based balance training and digitally augmented core stabilization on postural control and fall risk in postmenopausal women with osteoporosis. Read more about this study
- Who is it for?
- Ages 45 to 70 years, women only
- Conditions the study is for
- Postmenopausal Osteoporosis
- What is being tested?
- Sensorimotor-Based Balance Training and Digitally Augmented Core Stabilization
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 sitePakistan
- Study dates
- Sep 2026to 31 Jul 2027
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 70 years
- Women only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- PMW diagnosed with osteoporosis through DEXA (T-score ≤ -2.5)
- Age (45-70 years).
- Able to participate in sessions and walk independently.
- Mild to moderate Balance impairment as per BBS
Who cannot join
- • Women with severe mobility impairments.
- History of fragility fracture within the last 6 months
- Women with cognitive conditions affecting participation.
- Women with lower limb joint injury or surgery.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Muhammad Adnan Saeed
Islamabad, Federal, 44000
Muhammad Adnan Saeed, PhD, +93219565124, dasnmc@gmail.com
About this study
Official title: Effects of Sensorimotor-Based Balance Training Versus Digitally Augmented Core Stabilization on Postural Control and Fall Risk in Postmenopausal Women With Osteoporosis
This randomized controlled trial aims to compare the effects of sensorimotor-based balance training and digitally augmented core stabilization on postural control and fall risk in postmenopausal women with osteoporosis. Osteoporosis is a common condition in postmenopausal women that can impair balance, reduce functional mobility, and increase the risk of falls and fractures. Eligible participants will be randomly assigned to one of two intervention groups. Group A will receive a structured sensorimotor-based balance training program, while Group B will receive a digitally augmented core stabilization exercise program supported through the HEP2Go platform and monitored via WhatsApp. Both groups will receive supervised physiotherapy sessions three times per week for 8 weeks. Outcome measures including postural control, fall risk, spinal alignment, core muscle endurance, proprioception, muscle strength, adherence, and usability will be assessed before and after the intervention. The findings of this study may provide evidence regarding effective physiotherapy strategies for improving balance and reducing fall risk in postmenopausal women with osteoporosis.
Read the detailed description
Osteoporosis is a progressive skeletal disorder characterized by reduced bone mineral density and deterioration of bone microarchitecture, resulting in increased bone fragility and susceptibility to fractures. Postmenopausal women are particularly affected because estrogen deficiency accelerates bone loss, leading to impaired postural stability, reduced muscle strength, proprioceptive deficits, and an increased risk of falls. Falls are a major cause of morbidity, disability, and reduced quality of life among women with osteoporosis.
Exercise-based physiotherapy is an important non-pharmacological intervention for improving balance, postural control, muscle strength, and functional mobility in individuals with osteoporosis. Sensorimotor-based balance training aims to improve proprioception, neuromuscular coordination, and postural stability through progressively challenging balance and functional activities. Core stabilization exercises focus on strengthening deep trunk muscles to improve spinal stability, posture, and movement control.
Digital rehabilitation technologies have increasingly been incorporated into physiotherapy practice to improve exercise adherence, accessibility, and patient engagement. In this study, digital augmentation will be delivered through the HEP2Go platform by providing individualized home exercise programs with exercise illustrations and written instructions. Participants in the digitally augmented group will also receive regular follow-up and adherence monitoring through WhatsApp communication with the assistance of caregivers.
This study will be conducted as a randomized controlled trial involving postmenopausal women diagnosed with osteoporosis. Eligible participants who satisfy the inclusion criteria and provide written informed consent will undergo baseline assessment and then be randomly allocated to one of two intervention groups. Group A will receive a structured sensorimotor-based balance training program, whereas Group B will receive a digitally augmented core stabilization exercise program. Both interventions will be administered three times per week for 8 weeks.
Primary outcomes include postural control and fall risk. Secondary outcomes include thoracic kyphosis angle, core muscle endurance, lumbar joint position sense, trunk extensor strength, exercise adherence, and system usability. Outcome measures will be recorded before and after completion of the intervention using standardized assessment tools. Data will be analyzed using SPSS version 26 to compare within-group and between-group changes.
- Conditions
- Postmenopausal Osteoporosis
- Being tested
- Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization
- Keywords
- Postmenopausal Osteoporosis, Sensorimotor-Based Balance Training, Core Stabilization, Digitally Augmented Rehabilitation, Postural Control, Fall Risk, Balance Training, Women's Health Physical Therapy, Exercise Therapy, Postmenopausal Women, Osteoporosis Rehabilitation, Randomized Controlled Trial, Tele-rehabilitation, Physiotherapy
- Medical subject headings
- Osteoporosis, Postmenopausal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sensorimotor-Based Balance TrainingBehavioural
A supervised sensorimotor-based balance training program comprising progressive static and dynamic balance exercises, proprioceptive training, gait training, lower-limb strengthening, functional balance activities, and cool-down exercises. Sessions will be conducted three times per week for 8-12 weeks to improve postural control, balance, and functional mobility in postmenopausal women with osteoporosis.
Digitally Augmented Core StabilizationBehavioural
A supervised core stabilization exercise program focusing on activation and strengthening of deep trunk muscles, postural alignment, and functional stability. Digital augmentation will be provided through the HEP2Go platform by delivering individualized home exercise programs with exercise illustrations and written instructions. Participants will also receive regular WhatsApp reminders, educational support, and adherence monitoring throughout the 8-12-week intervention period.
| Study group | Role | What they receive |
|---|---|---|
| Sensorimotor-Based Balance Training | Experimental | Participants assigned to this arm will receive a structured sensorimotor-based balance training program aimed at improving postural control, proprioception, balance, and reducing fall risk in postmenopausal women with osteoporosis. The intervention consists of warm-up exercises, static and dynamic balance training, sensorimotor and proprioceptive exercises, gait and functional training, lower-limb strengthening exercises, and cool-down activities. Supervised physiotherapy sessions will be conducted three times per week for 8 weeks, with progressive exercise intensity according to participant tolerance. Receives: Behavioral: Sensorimotor-Based Balance Training |
| Digitally Augmented Core Stabilization | Experimental | Participants assigned to this arm will receive a structured core stabilization exercise program enhanced through digital augmentation using the HEP2Go platform. Individualized home exercise programs containing exercise illustrations and written instructions will be provided through HEP2Go. The intervention includes warm-up, deep core muscle activation, core stabilization exercises, functional core training, postural training, and cool-down exercises. Supervised physiotherapy sessions will be conducted three times per week for 8 weeks. Exercise adherence and progress will be monitored through regular WhatsApp communication with participants and their caregivers. Receives: Behavioral: Digitally Augmented Core Stabilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postural Control (Mini-BESTest)
Postural control will be assessed using the Mini-Balance Evaluation Systems Test (Mini-BESTest), a 14-item clinical measure of postural control. Total scores range from 0 to 28 points, with higher scores indicating better postural control.
Measured: Baseline (pre-intervention) and immediately after completion of the 8-week intervention.
Fall Risk
Fall risk will be assessed using the Timed Up and Go (TUG) Test. Time is recorded in seconds, with shorter completion times indicating better functional mobility and lower fall risk.
Measured: Baseline (pre-intervention) and immediately after completion of the 8-week intervention.
Secondary outcomes (6)
Thoracic Kyphosis Angle
Thoracic kyphosis angle will be measured using a Flexicurve ruler.
Measured: Baseline and immediately after completion of the 8-week intervention.
Core Muscle Endurance
core muscle endurance will be assessed using the Modified McGill Trunk Endurance Test.
Measured: Baseline and immediately after completion of the 8-week intervention
Proprioception
Lumbar proprioception will be assessed using the lumbar joint position sense repositioning error test.
Measured: Baseline and immediately after completion of the 8-week intervention.
Trunk Extensor Muscle Strength
Trunk extensor muscle strength will be measured using a handheld dynamometer.
Measured: Baseline and immediately after completion of the 8-week intervention.
Exercise Adherence
Exercise adherence will be evaluated using attendance records and home exercise adherence logs throughout the intervention period.
Measured: Throughout the 8-week intervention period.
System Usability
System usability of the digitally augmented intervention will be assessed using the System Usability Scale (SUS). The SUS consists of 10 items and provides a total score ranging from 0 to 100 points, with higher scores indicating better perceived usability of the digitally augmented intervention.
Measured: At the end of the 8-week intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Oct 2026
- Study startSep 2026 (estimated)
- Primary completion30 Jun 2027 (estimated)
- Study completion31 Jul 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for Postmenopausal OsteoporosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- A will receive sensorimotor-based balance training, while Group B will receive a digitally augmented core stabilization exercise program. Both interventions will be delivered over a 8-week period with supervised sessions three times per week. Outcome measures will be assessed at baseline and after completion of the intervention. Participants will remain in their assigned group throughout the study, and no crossover between groups will occur.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Huma Riaz, Principal investigator, Riphah International University, Islamabad
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07875894
- Sponsor's protocol ID
- Hadia
- Status last verified
- Oct 2026
- First submitted
- 16 Sep 2026
- Last updated
- 15 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared publicly because the dataset contains confidential participant information collected for an academic research project. Data will be stored securely and used only for the purposes of this study. Any future sharing of de-identified data will require approval from the Institutional Review Board/Ethics Committee and the principal investigator, in accordance with institutional policies and participant consent.
Publications
Mohebbi R, Shojaa M, Kohl M, von Stengel S, Jakob F, Kerschan-Schindl K, Lange U, Peters S, Thomasius F, Uder M, Kemmler W. Exercise training and bone mineral density in postmenopausal women: an updated systematic review and meta-analysis of intervention studies with emphasis on potential moderators. Osteoporos Int. 2023 Jul;34(7):1145-1178. doi: 10.1007/s00198-023-06682-1. Epub 2023 Feb 7.
PubMed 36749350Zhou X, Deng H, Shen X, Lei Q. Effect of balance training on falls in patients with osteoporosis: A systematic review and meta-analysis. J Rehabil Med. 2018 Jul 17;50(7):577-581. doi: 10.2340/16501977-2334.
PubMed 29767225Wei F, Hu Z, He R, Wang Y. Effects of balance training on balance and fall efficacy in patients with Osteoporosis: A systematic review and meta-analysis with trial sequential analysis. J Rehabil Med. 2023 May 17;55:jrm00390. doi: 10.2340/jrm.v55.4529.
PubMed 37194565Alonso Perez JL, Martin Perez S, Battaglino A, Villafane JH, Alonso-Sal A, Sanchez Romero EA. An Up-Date of the Muscle Strengthening Exercise Effectiveness in Postmenopausal Women with Osteoporosis: A Qualitative Systematic Review. J Clin Med. 2021 May 21;10(11):2229. doi: 10.3390/jcm10112229.
PubMed 34063906Anupama DS, Norohna JA, Acharya KK, Ravishankar, George A. Effect of exercise on bone mineral density and quality of life among postmenopausal women with osteoporosis without fracture: A systematic review. Int J Orthop Trauma Nurs. 2020 Nov;39:100796. doi: 10.1016/j.ijotn.2020.100796. Epub 2020 Jul 28.
PubMed 33041224Kemmler W, Shojaa M, Kohl M, von Stengel S. Effects of Different Types of Exercise on Bone Mineral Density in Postmenopausal Women: A Systematic Review and Meta-analysis. Calcif Tissue Int. 2020 Nov;107(5):409-439. doi: 10.1007/s00223-020-00744-w. Epub 2020 Aug 12.
PubMed 32785775