Accelerate Tooth MovementLLLT- piezoNCT07873853
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth
A study testing low level LAZER therapy., Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. and Piezocision-assisted orthodontic retraction in people with Accelerate Tooth Movement, run by Al-Azhar University at 1 site in Egypt.
Trial summary
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation (Comparative Clinical Study) Read more about this study
- Who is it for?
- Ages 14 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Accelerate Tooth Movement
- What is being tested?
- low level LAZER therapy., Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. and Piezocision-assisted orthodontic retraction
- Type of treatment
- Medical device, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Nov 2026to 1 Aug 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 25 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Age between 14 to 25.
- Patients who need upper or all four first premolar extraction for canine retraction.
- No systemic disease.
- No previous extraction of permanent teeth.
- Not receiving medical treatment that could interfere with bone metabolism.
- A good level of oral hygiene.
- No periodontal disease or radiographic evidence of bone loss
Who cannot join
- 1. Periodontally compromised patients. 2. Missing teeth. 3. Systemic diseases. 4. Drug dependencies. 5. Uncooperative patient.
- -
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Department of Orthodontic,Faculty Of Dental Medicine ,AL-Azhar University ,Assuit Branch
Asyut
Mohamed Ahmed Mohamed, Professor, +201092901408, mohamed.a.salem.46@azhar.edu.eg
Mohamed Ahmed Salim, Professor, esmailhewy1459.el@azhar.edu.eg
About this study
Official title: Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation (Comparative Clinical Study)
Read the detailed description
This study will be conducted as a prospective, control, clinical trial, a convenience sampling technique was used for patient selection.
- Conditions
- Accelerate Tooth Movement
- Being tested
- low level LAZER therapy., Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods., Piezocision-assisted orthodontic retraction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
low level LAZER therapy.Device
Application of low-level laser therapy (LLLT) as an adjunct to conventional en-masse retraction to accelerate tooth movement.
Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods.Procedure or surgery
Standard en-masse retraction using conventional orthodontic mechanics without adjunctive acceleration techniques.
Piezocision-assisted orthodontic retractionProcedure or surgery
Minimally invasive surgical procedure (piezocision) used alongside conventional mechanics to facilitate accelerated tooth movement during en-masse retraction.
| Study group | Role | What they receive |
|---|---|---|
| Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. | Experimental | Not described Receives: Procedure: Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. |
| Retraction of Maxillary Anterior Teeth (en-mass) aided with low level LAZER therapy. | Experimental | Not described Receives: Device: low level LAZER therapy. |
| Retraction of Maxillary Anterior Teeth (en-mass) aided with piezocision method. | Experimental | Not described Receives: Procedure: Piezocision-assisted orthodontic retraction |
What is being measured
The primary outcome is the main question the study is designed to answer.
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth
To evaluate and compare the rate and amount of en-masse retraction of maxillary anterior teeth using different orthodontic acceleration techniques through digital software analysis.
Measured: Base line (T0), 1 month (T1), 2months (T2), and 3months(T3) after the start of retraction
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Oct 2026
- Study start1 Nov 2026 (estimated)
- Primary completion1 Apr 2028 (estimated)
- Study completion1 Aug 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Accelerate Tooth MovementStudies of the same condition, open and under way.
- More trials run by Al-Azhar UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 24 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Al-Azhar University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Alhassan Hatem Mohamed, Al-Azhar University
- Investigators
- Mohamed Ahmed Salim, Professor, Study director, Al-Azhar University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07873853
- Sponsor's protocol ID
- Alazhar U
- Acronym
- LLLT- piezo
- Status last verified
- Aug 2026
- First submitted
- 22 Jul 2025
- Last updated
- 4 Nov 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Nov 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation
- ClinicalTrials.gov ID
- NCT07873853
- Acronym / sponsor ID
- LLLT- piezo / Alazhar U
- Conditions
- Accelerate Tooth Movement
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 24 participants (estimated)
- Lead sponsor
- Al-Azhar UniversityUniversity, hospital or other
- Study start
- 1 Nov 2026 (estimated)
- Primary completion
- 1 Apr 2028 (estimated)
- Study completion
- 1 Aug 2028 (estimated)
- First posted
- 14 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth: A Digital Software Evaluation (Comparative Clinical Study)
Detailed description
This study will be conducted as a prospective, control, clinical trial, a convenience sampling technique was used for patient selection.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. | Experimental | Procedure: Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. |
| Retraction of Maxillary Anterior Teeth (en-mass) aided with low level LAZER therapy. | Experimental | Device: low level LAZER therapy. |
| Retraction of Maxillary Anterior Teeth (en-mass) aided with piezocision method. | Experimental | Procedure: Piezocision-assisted orthodontic retraction |
Who may qualify
- Ages
- 14 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (7 listed)
- Age between 14 to 25.
- Patients who need upper or all four first premolar extraction for canine retraction.
- No systemic disease.
- No previous extraction of permanent teeth.
- Not receiving medical treatment that could interfere with bone metabolism.
Key exclusion criteria (2 listed)
- 1. Periodontally compromised patients. 2. Missing teeth. 3. Systemic diseases. 4. Drug dependencies. 5. Uncooperative patient.
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| low level LAZER therapy.Application of low-level laser therapy (LLLT) as an adjunct to conventional en-masse retraction to accelerate tooth movement. | Device | Retraction of Maxillary Anterior Teeth (en-mass) aided with low level LAZER therapy. |
| Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods.Standard en-masse retraction using conventional orthodontic mechanics without adjunctive acceleration techniques. | Procedure or surgery | Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. |
| Piezocision-assisted orthodontic retractionMinimally invasive surgical procedure (piezocision) used alongside conventional mechanics to facilitate accelerated tooth movement during en-masse retraction. | Procedure or surgery | Retraction of Maxillary Anterior Teeth (en-mass) aided with piezocision method. |
Primary outcome
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth
Time frame: Base line (T0), 1 month (T1), 2months (T2), and 3months(T3) after the start of retraction
To evaluate and compare the rate and amount of en-masse retraction of maxillary anterior teeth using different orthodontic acceleration techniques through digital software analysis.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Nov 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Mohamed Ahmed Salim, Professor study director
Al-Azhar University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing low level LAZER therapy., Retraction of Maxillary Anterior Teeth (en-mass) with conventional methods. and Piezocision-assisted orthodontic retraction in people with Accelerate Tooth Movement, run by Al-Azhar University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 4 Nov 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact AL-Hassan Hatem Mohamed (+201029086038, alhasanhatem49@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Impact of Various Acceleration Techniques on En-masse Retraction of Maxillary Anterior Teeth (time frame: Base line (T0), 1 month (T1), 2months (T2), and 3months(T3) after the start of retraction). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Nov 2026.