Athletic InjuryPREDICTYOUTHNCT07870460
Multimodal Machine Learning for Predicting Reduced Participation in Elite Youth Football
An observational study of Athletic Injury and Fatigue Recovery, run by Palacky University at 1 site in Czechia.
Trial summary
This study protocol describes a prospective longitudinal observational study designed to evaluate the accuracy of machine learning models in predicting the short-term (24-72 h) risk of reduced participation (training modification or absence due to health complaints, injury, or illness) among elite youth football… Read more about this study
- Who is it for?
- Ages 15 to 19 years, men onlyHealthy volunteers can take part
- Conditions the study is for
- Athletic Injury, Fatigue Recovery
- How many people
- 30 participants
- Where
- 1 siteCzechia
- Study dates
- 15 Jul 2026to 30 Jun 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 19 years
- Men only
- Healthy volunteers accepted
- Child, Adult
Study population: Elite male youth football players (categories U16 and U19) registered in a licensed national youth football academy (SK Sigma Olomouc, Czechia) competing in top-tier national youth leagues.
Who may be able to join
- Registered player in the U16 or U19 squad of an elite football academy (SK Sigma Olomouc).
- At least three years of structured football training within an organized academy programme.
- Regular active participation in microcycle team training and competitive league matches.
- Written informed assent by the player and written informed consent by a parent or legal guardian (for minor participants).
- Monitoring compliance rate > 80% during the initial 14-day passive run-in period.
Who cannot join
- Pre-existing severe musculoskeletal injury, orthopedic surgery, or neurological disorder preventing full participation at baseline.
- Known cardiovascular, metabolic, or systemic disease contraindicating maximal athletic exertion.
- Inability or refusal to wear continuous monitoring sensors (Catapult GNSS unit during training, WHOOP strap during sleep).
- Prolonged absence from the squad due to non-medical administrative reasons (transfer, academic leave, disciplinary suspension).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Czechia1 site, 1 recruiting
- Recruiting
SK Sigma Olomouc Academy & AC Baluo, Palacký University Olomouc
Olomouc, 77900
David Prycl, Mgr., +420775111781, david.prycl@upol.cz
About this study
Official title: Machine Learning-Based Short-Term Prediction of Reduced Participation Within the Competitive Microcycle in Elite Youth Football Players Using Multimodal Data
This study protocol describes a prospective longitudinal observational study designed to evaluate the accuracy of machine learning models in predicting the short-term (24-72 h) risk of reduced participation (training modification or absence due to health complaints, injury, or illness) among elite youth football players (categories U16 to U19).
Full participation in training and matches is a key determinant of athletic development and squad availability in elite youth football. Conventional injury surveillance typically reduces athlete availability to a binary time-loss state and overlooks the continuum on which athletes remain active despite emerging fatigue, minor musculoskeletal complaints, or functional limitations.
Read more
In this study, continuous multimodal monitoring integrates external training and match locomotion (Catapult Vector 10 Hz GNSS / 100 Hz IMU), nocturnal autonomic nervous regulation (WHOOP 5.0 wrist-worn photoplethysmography evaluating resting heart rate, heart rate variability RMSSD, and sleep architecture), daily subjective wellness (AMS Hooper Index: sleep quality, stress, fatigue, mood, and muscle soreness), weekly neuromuscular screening (VALD ForceDecks countermovement jumps and NordBord hamstring strength), and anthropometrics with biological maturation offset.
Participation status is adjudicated daily by designated coaching and medical staff. The primary objective is to develop, compare, and internally validate short-term prediction models for the onset transition from full participation to reduced participation, formulated as a single one-step discrete-time hazard read coherently across 24-, 48-, and 72-hour operational horizons. The study aims to evaluate explainable machine learning models (Survival XGBoost, GAMM with SHAP/LIME interpretation) to support training load management and injury risk mitigation within elite academies.
Read the detailed description
STUDY DESIGN AND COHORT:
This is a prospective, longitudinal, single-site observational cohort study conducted across one complete 10-month competitive season (2026/2027) within the U16 and U19 squads of an elite youth football academy (SK Sigma Olomouc, Czechia). The cohort comprises approximately 30 elite male youth football players. The unit of analysis is the at-risk player-day in full participation (longitudinal person-period array), yielding an estimated 6,000 to 8,000 observed player-days.
PRIMARY OUTCOME (TARGET VARIABLE):
The primary outcome is the staff-adjudicated transition event from full participation into any lower category of the daily participation gradient (modified training with >20% volume reduction, reduced training intensity, or complete absence due to medical/health reasons). Conditional on full participation on day t, the primary modeled quantity is the one-step discrete-time onset hazard. Operational cumulative onset probabilities are read coherently across 24-, 48-, and 72-hour horizons. To ensure outcome adjudication reliability, an inter-rater agreement analysis (Cohen's kappa) is performed between independent staff members.
MULTIMODAL PREDICTOR DOMAINS:
Candidate predictors span eight pre-specified canonical domains (~31 candidate variables; ~33-36 parameters after categorical expansion):
- Player Profile \& Maturation: Baseline anthropometry, body composition (InBody 230: FFM, % body fat), and biological maturation offset (Mirwald equation).
- External Load: Catapult Vector GNSS/IMU metrics (total distance, high-speed running >20 km/h, sprinting >25.2 km/h, accelerations/decelerations >3.0 m/s², PlayerLoad).
- Internal Load: Daily heart rate telemetry and session-RPE derived metrics (training monotony and training strain).
- Autonomic Recovery \& Sleep: Continuously recorded overnight via WHOOP 5.0 wrist-worn wearable bands (resting heart rate, HRV RMSSD during slow-wave sleep, sleep architecture, and skin temperature).
- Neuromuscular Capacity: Repeated weekly neuromuscular screening on VALD Systems (ForceFrame hip adduction/abduction and NordBord eccentric/isometric hamstring strength and bilateral asymmetries).
- Performance Capacity: Periodic physical testing (sprint times, change of direction, and jump mechanics).
- Contextual Factors: Microcycle schedule (days to/from match day), match congestion, and playing position.
- Daily Subjective Wellness: Morning perceptual ratings on a 1-5 Likert scale (Hooper index: sleep, fatigue, stress, soreness). An objective-only sensitivity model will explicitly exclude subjective wellness to prevent construct overlap and circularity.
RESAMPLING AND LEAKAGE DISCIPLINE:
Model evaluation operates via a calendar-aligned rolling-origin cross-validation scheme with an expanding training window and temporally subsequent held-out test blocks. To prevent data leakage across the train/test boundary, an embedded temporal embargo of >=72 hours is implemented. All data-dependent preprocessing steps (imputation via MICE/PMM, scaling, dimensionality reduction) are fitted strictly within the training partition of each resample and applied to held-out test data.
STATISTICAL MODELLING AND EVALUATION:
Pre-specified candidate models include baseline logistic regressions, Generalised Additive Mixed Models (GAMM) with player-level random intercepts, and tree-based learners (Survival XGBoost with functional monotonicity constraints). Model evaluation follows a calibration-first hierarchy (Brier score, calibration slopes/curves), followed by discrimination under class imbalance (Precision-Recall AUC, Matthews Correlation Coefficient). Model behavior and domain contributions are interpreted using explainable artificial intelligence (XAI) frameworks (SHAP and LIME).
- Conditions
- Athletic Injury, Fatigue Recovery
- Keywords
- injury prevention, machine learning, multimodal monitoring, catapult GPS, WHOOP HRV, VALD dynamometry, reduced participation, youth football
- Medical subject headings
- Athletic Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Elite Youth Football Squads (U16 & U19) | Approximately 30 registered male youth football players from U16 and U19 academy squads (SK Sigma Olomouc) undergoing regular training and competitive match microcycles with continuous multimodal monitoring across one full season. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Short-Term Incidence of Change in Participation Status (24, 48, and 72-Hour Discrete-Time Hazard)
Daily morning consensus assessment (at 8:30 AM) of player participation recorded in the club Athlete Management System (AMS) on a 3-point ordinal scale: Full participation (0), Modified training with >20% volume restriction or sprint restriction due to medical/health complaints (1), and Complete absence due to injury or illness (2). Transitions from full participation to modified training or absence (Levels 1 and 2) are modeled as a binary event of participation status change under a discrete-time survival framework with a 3-day clean washout period (W = 3) for re-entry into the risk set.
Measured: Daily assessments across one complete 10-month competitive football season (predicting transitions within 24, 48, and 72 hours).
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Oct 2026
- Study start15 Jul 2026
- Primary completion30 Jun 2027 (estimated)
- Study completion30 Jun 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Athletic InjuryStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Palacky University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Karel Hulka, Palacky University
- Investigators
- Karel Hulka, doc. Mgr., Ph.D., Study director, Palacky University Olomouc
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07870460
- Sponsor's protocol ID
- IGA_FTK_2026_002
- Acronym
- PREDICTYOUTH
- Status last verified
- Oct 2026
- First submitted
- 6 Oct 2026
- Last updated
- 15 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Machine Learning-Based Short-Term Prediction of Reduced Participation Within the Competitive Microcycle in Elite Youth Football Players Using Multimodal Data
- ClinicalTrials.gov ID
- NCT07870460
- Acronym / sponsor ID
- PREDICTYOUTH / IGA_FTK_2026_002
- Conditions
- Athletic Injury, Fatigue Recovery
- Keywords
- injury prevention, machine learning, multimodal monitoring, catapult GPS, WHOOP HRV, VALD dynamometry, reduced participation, youth football
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Palacky UniversityUniversity, hospital or other
- Study start
- 15 Jul 2026 (actual)
- Primary completion
- 30 Jun 2027 (estimated)
- Study completion
- 30 Jun 2028 (estimated)
- First posted
- 13 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study protocol describes a prospective longitudinal observational study designed to evaluate the accuracy of machine learning models in predicting the short-term (24-72 h) risk of reduced participation (training modification or absence due to health complaints, injury, or illness) among elite youth football players (categories U16 to U19).
Full participation in training and matches is a key determinant of athletic development and squad availability in elite youth football. Conventional injury surveillance typically reduces athlete availability to a binary time-loss state and overlooks the continuum on which athletes remain active despite emerging fatigue, minor musculoskeletal complaints, or functional limitations.
In this study, continuous multimodal monitoring integrates external training and match locomotion (Catapult Vector 10 Hz GNSS / 100 Hz IMU), nocturnal autonomic nervous regulation (WHOOP 5.0 wrist-worn photoplethysmography evaluating resting heart rate, heart rate variability RMSSD, and sleep architecture), daily subjective wellness (AMS Hooper Index: sleep quality, stress, fatigue, mood, and muscle soreness), weekly neuromuscular screening (VALD ForceDecks countermovement jumps and NordBord hamstring strength), and anthropometrics with biological maturation offset.
Participation status is adjudicated daily by designated coaching and medical staff. The primary objective is to develop, compare, and internally validate short-term prediction models for the onset transition from full participation to reduced participation, formulated as a single one-step discrete-time hazard read coherently across 24-, 48-, and 72-hour operational horizons. The study aims to evaluate explainable machine learning models (Survival XGBoost, GAMM with SHAP/LIME interpretation) to support training load management and injury risk mitigation within elite academies.
Detailed description
STUDY DESIGN AND COHORT:
This is a prospective, longitudinal, single-site observational cohort study conducted across one complete 10-month competitive season (2026/2027) within the U16 and U19 squads of an elite youth football academy (SK Sigma Olomouc, Czechia). The cohort comprises approximately 30 elite male youth football players. The unit of analysis is the at-risk player-day in full participation (longitudinal person-period array), yielding an estimated 6,000 to 8,000 observed player-days.
PRIMARY OUTCOME (TARGET VARIABLE):
The primary outcome is the staff-adjudicated transition event from full participation into any lower category of the daily participation gradient (modified training with >20% volume reduction, reduced training intensity, or complete absence due to medical/health reasons). Conditional on full participation on day t, the primary modeled quantity is the one-step discrete-time onset hazard. Operational cumulative onset probabilities are read coherently across 24-, 48-, and 72-hour horizons. To ensure outcome adjudication reliability, an inter-rater agreement analysis (Cohen's kappa) is performed between independent staff members.
MULTIMODAL PREDICTOR DOMAINS:
Candidate predictors span eight pre-specified canonical domains (~31 candidate variables; ~33-36 parameters after categorical expansion):
- Player Profile \& Maturation: Baseline anthropometry, body composition (InBody 230: FFM, % body fat), and biological maturation offset (Mirwald equation).
- External Load: Catapult Vector GNSS/IMU metrics (total distance, high-speed running >20 km/h, sprinting >25.2 km/h, accelerations/decelerations >3.0 m/s², PlayerLoad).
- Internal Load: Daily heart rate telemetry and session-RPE derived metrics (training monotony and training strain).
- Autonomic Recovery \& Sleep: Continuously recorded overnight via WHOOP 5.0 wrist-worn wearable bands (resting heart rate, HRV RMSSD during slow-wave sleep, sleep architecture, and skin temperature).
- Neuromuscular Capacity: Repeated weekly neuromuscular screening on VALD Systems (ForceFrame hip adduction/abduction and NordBord eccentric/isometric hamstring strength and bilateral asymmetries).
- Performance Capacity: Periodic physical testing (sprint times, change of direction, and jump mechanics).
- Contextual Factors: Microcycle schedule (days to/from match day), match congestion, and playing position.
- Daily Subjective Wellness: Morning perceptual ratings on a 1-5 Likert scale (Hooper index: sleep, fatigue, stress, soreness). An objective-only sensitivity model will explicitly exclude subjective wellness to prevent construct overlap and circularity.
RESAMPLING AND LEAKAGE DISCIPLINE:
Model evaluation operates via a calendar-aligned rolling-origin cross-validation scheme with an expanding training window and temporally subsequent held-out test blocks. To prevent data leakage across the train/test boundary, an embedded temporal embargo of >=72 hours is implemented. All data-dependent preprocessing steps (imputation via MICE/PMM, scaling, dimensionality reduction) are fitted strictly within the training partition of each resample and applied to held-out test data.
STATISTICAL MODELLING AND EVALUATION:
Pre-specified candidate models include baseline logistic regressions, Generalised Additive Mixed Models (GAMM) with player-level random intercepts, and tree-based learners (Survival XGBoost with functional monotonicity constraints). Model evaluation follows a calibration-first hierarchy (Brier score, calibration slopes/curves), followed by discrimination under class imbalance (Precision-Recall AUC, Matthews Correlation Coefficient). Model behavior and domain contributions are interpreted using explainable artificial intelligence (XAI) frameworks (SHAP and LIME).
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Elite Youth Football Squads (U16 & U19) | – | –Approximately 30 registered male youth football players from U16 and U19 academy squads (SK Sigma Olomouc) undergoing regular training and competitive match microcycles with continuous multimodal monitoring across one full season. |
Who may qualify
- Ages
- 15 to 19 years
- Sex
- Male only
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
- Study population
- Elite male youth football players (categories U16 and U19) registered in a licensed national youth football academy (SK Sigma Olomouc, Czechia) competing in top-tier national youth leagues.
Key inclusion criteria (5 listed)
- Registered player in the U16 or U19 squad of an elite football academy (SK Sigma Olomouc).
- At least three years of structured football training within an organized academy programme.
- Regular active participation in microcycle team training and competitive league matches.
- Written informed assent by the player and written informed consent by a parent or legal guardian (for minor participants).
- Monitoring compliance rate > 80% during the initial 14-day passive run-in period.
Key exclusion criteria (4 listed)
- Pre-existing severe musculoskeletal injury, orthopedic surgery, or neurological disorder preventing full participation at baseline.
- Known cardiovascular, metabolic, or systemic disease contraindicating maximal athletic exertion.
- Inability or refusal to wear continuous monitoring sensors (Catapult GNSS unit during training, WHOOP strap during sleep).
- Prolonged absence from the squad due to non-medical administrative reasons (transfer, academic leave, disciplinary suspension).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Short-Term Incidence of Change in Participation Status (24, 48, and 72-Hour Discrete-Time Hazard)
Time frame: Daily assessments across one complete 10-month competitive football season (predicting transitions within 24, 48, and 72 hours).
Daily morning consensus assessment (at 8:30 AM) of player participation recorded in the club Athlete Management System (AMS) on a 3-point ordinal scale: Full participation (0), Modified training with >20% volume restriction or sprint restriction due to medical/health complaints (1), and Complete absence due to injury or illness (2). Transitions from full participation to modified training or absence (Levels 1 and 2) are modeled as a binary event of participation status change under a discrete-time survival framework with a 3-day clean washout period (W = 3) for re-entry into the risk set.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Karel Hulka, doc. Mgr., Ph.D. study director
Palacky University Olomouc
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Athletic Injury and Fatigue Recovery, run by Palacky University at 1 site in Czechia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Czechia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact David Prycl (775111781, david.prycl@upol.cz), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Short-Term Incidence of Change in Participation Status (24, 48, and 72-Hour Discrete-Time Hazard) (time frame: Daily assessments across one complete 10-month competitive football season (predicting transitions within 24, 48, and 72 hours).). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Oct 2026; AzTrials last refreshed its copy on 26 Oct 2026.