Obesity, Morbid Catheterization, PeripheralNCT07868978
Radial Artery Dimensions and the Effect of Anaesthetic Induction in Morbid Obesity
A study testing 20 G arterial cannula and 18 G arterial cannula in people with Obesity, Morbid Catheterization, Peripheral, run by Hilal Subaşı Artıran at 1 site in Turkey (Türkiye).
Trial summary
This single-centre prospective study measured the internal diameter of the radial artery and the distance between the skin surface and the arterial lumen by ultrasound in 76 adults with a body mass index of 40 kg/m2 or above who were scheduled for elective surgery under general anaesthesia. Read more about this study
- Who is it for?
- Ages 18 to 60 years
- Conditions the study is for
- Obesity, Morbid Catheterization, Peripheral
- What is being tested?
- 20 G arterial cannula and 18 G arterial cannula
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 76 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 5 Nov 2020to 10 Mar 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age 18 to 60 years
- Body mass index 40 kg/m2 or above
- American Society of Anesthesiologists physical status III
- Scheduled for elective surgery under general anaesthesia
Who cannot join
- Refusal to participate
- Haemodynamic instability
- Coronary artery disease
- Peripheral artery disease
- Diabetes mellitus
- Hypertension
- Known radial or ulnar vascular pathology
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaşa
Istanbul
About this study
Official title: Ultrasonographic Dimensions of the Radial Artery in Morbidly Obese Patients and the Effect of General Anaesthesia Induction on Arterial Diameter: A Prospective Observational Study With a Nested Randomised Cannula Comparison
This single-centre prospective study measured the internal diameter of the radial artery and the distance between the skin surface and the arterial lumen by ultrasound in 76 adults with a body mass index of 40 kg/m2 or above who were scheduled for elective surgery under general anaesthesia. Measurements were made 2 cm proximal to the radial styloid process before induction of anaesthesia and again 5 minutes after endotracheal intubation, so that each patient served as their own control. The relationship of these measurements with anthropometric variables was examined. Patients were additionally randomized to radial artery cannulation with either an 18 G or a 20 G cannula, and the two cannula gauges were compared with respect to the time to successful cannulation and the number of skin punctures.
- Being tested
- 20 G arterial cannula, 18 G arterial cannula
- Keywords
- radial artery; ultrasonography, interventional; anaesthesia, general; arterial cannulation; body mass index
- Medical subject headings
- Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
20 G arterial cannulaDevice
Ultrasound-guided radial artery cannulation using a 20 G arterial cannula. The probe was placed in the short axis to identify the artery and cannulation was performed in the long axis
18 G arterial cannulaDevice
Ultrasound-guided radial artery cannulation using an 18 G arterial cannula, by the same technique.
| Study group | Role | What they receive |
|---|---|---|
| 20 G cannula | Active comparator | Radial artery cannulation with a 20 G arterial cannula (outer diameter 1.1 mm, length 32 mm) after the second ultrasound measurement. n = 38 Receives: Device: 20 G arterial cannula; Device: 18 G arterial cannula |
| 18 G cannula | Active comparator | Radial artery cannulation with an 18 G arterial cannula (outer diameter 1.3 mm, length 45 mm) after the second ultrasound measurement. n = 38. Receives: Device: 20 G arterial cannula; Device: 18 G arterial cannula |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in internal diameter of the radial artery
Internal diameter of the radial artery measured by ultrasound in the long-axis view, 2 cm proximal to the radial styloid process, with the wrist in 45 degrees of extension. The outcome is the within-patient difference between the measurement before induction of anaesthesia and the measurement after intubation.
Measured: Before induction of anaesthesia and 5 minutes after endotracheal intubation
Secondary outcomes (4)
Distance between the skin surface and the radial artery lumen
Distance from the skin surface to the near wall of the radial artery lumen, measured by ultrasound at the same site and in the same plane as the diameter measurement.
Measured: Before induction of anaesthesia and 5 minutes after endotracheal intubation
Relationship between arterial dimensions and anthropometric variables
Correlation of radial artery diameter and skin-to-lumen distance with body weight, height, body mass index, body surface area, ideal body weight, wrist circumference, arm circumference and age.
Measured: At the time of the through study completion, an average of 4 months
Time to successful cannulation
Interval from placement of the ultrasound probe on the skin to the appearance of the arterial pressure waveform on the monitor. Compared between the two cannula gauges. Exploratory outcome.
Measured: During radial artery cannulation, immediately after the second ultrasound measurement
Number of skin punctures required for successful cannulation
Number of skin punctures until successful cannulation, compared between the two cannula gauges. Exploratory outcome
Measured: During radial artery cannulation, immediately after the second ultrasound measurement
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Oct 2026
- Study start5 Nov 2020
- Primary completion10 Mar 2021
- Study completion10 Mar 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obesity, Morbid Catheterization, PeripheralStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Observational paired measurement of radial artery dimensions before and after induction of general anaesthesia, with participants randomised to one of two cannula gauges for the subsequent arterial cannulation.
- Masking
- None (open label)
- Enrolment
- 76 participants (actual)
Sponsor and investigators
- Lead sponsor
- Hilal Subaşı Artıran
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Hilal Subaşı Artıran, Istanbul University - Cerrahpasa
- Investigators
- Department of Anaesthesiology and Reanimation Cerrahpaşa Faculty of Medicine, Istanbul University, Principal investigator, Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaş
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07868978
- Sponsor's protocol ID
- 72109855
- Other IDs
- 83045809-604.01.02-/A-39
- Status last verified
- Oct 2026
- First submitted
- 30 Sep 2026
- Last updated
- 9 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data are not available. The study was conducted as a medical specialty thesis and only aggregate data were retained.
Study at a glance
From the registry record, last updated by the sponsor on 9 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ultrasonographic Dimensions of the Radial Artery in Morbidly Obese Patients and the Effect of General Anaesthesia Induction on Arterial Diameter: A Prospective Observational Study With a Nested Randomised Cannula Comparison
- ClinicalTrials.gov ID
- NCT07868978
- Acronym / sponsor ID
- 72109855
- Keywords
- radial artery; ultrasonography, interventional; anaesthesia, general; arterial cannulation; body mass index
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 76 participants (actual)
- Lead sponsor
- Hilal Subaşı ArtıranUniversity, hospital or other
- Study start
- 5 Nov 2020 (actual)
- Primary completion
- 10 Mar 2021 (actual)
- Study completion
- 10 Mar 2021 (actual)
- First posted
- 9 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This single-centre prospective study measured the internal diameter of the radial artery and the distance between the skin surface and the arterial lumen by ultrasound in 76 adults with a body mass index of 40 kg/m2 or above who were scheduled for elective surgery under general anaesthesia. Measurements were made 2 cm proximal to the radial styloid process before induction of anaesthesia and again 5 minutes after endotracheal intubation, so that each patient served as their own control. The relationship of these measurements with anthropometric variables was examined. Patients were additionally randomized to radial artery cannulation with either an 18 G or a 20 G cannula, and the two cannula gauges were compared with respect to the time to successful cannulation and the number of skin punctures.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Observational paired measurement of radial artery dimensions before and after induction of general anaesthesia, with participants randomised to one of two cannula gauges for the subsequent arterial cannulation.
| Arm | Type | Receives |
|---|---|---|
| 20 G cannula | Active comparator | Device: 20 G arterial cannula, Device: 18 G arterial cannulaRadial artery cannulation with a 20 G arterial cannula (outer diameter 1.1 mm, length 32 mm) after the second ultrasound measurement. n = 38 |
| 18 G cannula | Active comparator | Device: 20 G arterial cannula, Device: 18 G arterial cannulaRadial artery cannulation with an 18 G arterial cannula (outer diameter 1.3 mm, length 45 mm) after the second ultrasound measurement. n = 38. |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Age 18 to 60 years
- Body mass index 40 kg/m2 or above
- American Society of Anesthesiologists physical status III
- Scheduled for elective surgery under general anaesthesia
Key exclusion criteria (7 listed)
- Refusal to participate
- Haemodynamic instability
- Coronary artery disease
- Peripheral artery disease
- Diabetes mellitus
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| 20 G arterial cannulaUltrasound-guided radial artery cannulation using a 20 G arterial cannula. The probe was placed in the short axis to identify the artery and cannulation was performed in the long axis | Device | 18 G cannula, 20 G cannula |
| 18 G arterial cannulaUltrasound-guided radial artery cannulation using an 18 G arterial cannula, by the same technique. | Device | 18 G cannula, 20 G cannula |
Primary outcome
Change in internal diameter of the radial artery
Time frame: Before induction of anaesthesia and 5 minutes after endotracheal intubation
Internal diameter of the radial artery measured by ultrasound in the long-axis view, 2 cm proximal to the radial styloid process, with the wrist in 45 degrees of extension. The outcome is the within-patient difference between the measurement before induction of anaesthesia and the measurement after intubation.
4 secondary outcomes
Distance between the skin surface and the radial artery lumen
Time frame: Before induction of anaesthesia and 5 minutes after endotracheal intubation
Relationship between arterial dimensions and anthropometric variables
Time frame: At the time of the through study completion, an average of 4 months
Time to successful cannulation
Time frame: During radial artery cannulation, immediately after the second ultrasound measurement
Number of skin punctures required for successful cannulation
Time frame: During radial artery cannulation, immediately after the second ultrasound measurement
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Oct 2026.
- Individual participant dataSharing planned: No. Individual participant data are not available. The study was conducted as a medical specialty thesis and only aggregate data were retained.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Department of Anaesthesiology and Reanimation Cerrahpaşa Faculty of Medicine, Istanbul University principal investigator
Cerrahpaşa Faculty of Medicine, Istanbul University-Cerrahpaş
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing 20 G arterial cannula and 18 G arterial cannula in people with Obesity, Morbid Catheterization, Peripheral, run by Hilal Subaşı Artıran at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in internal diameter of the radial artery (time frame: Before induction of anaesthesia and 5 minutes after endotracheal intubation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Oct 2026.