Postoperative PainNCT07863622
Assessment of Postoperative Pain Following Root Canal Obturation of Permanent Mature Teeth Using Three Different Obturation Techniques: A Randomized Clinical Trial
A study testing Cold Lateral condensation technique, Vibration thermo-dynamic technique and Injection of thermo-plasticized gutta-percha in people with Postoperative Pain, run by Tanta University at 1 site in Egypt.
Trial summary
purpose: to evaluate the postoperative pain incidence and intensity after three different obturation techniques (Cold lateral condensation technique (CLC), Vibration thermo-dynamic technique (Vibra-Tho) and Injection of thermo-plasticized gutta-percha (Fast Fill device)). Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Cold Lateral condensation technique, Vibration thermo-dynamic technique and Injection of thermo-plasticized gutta-percha
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteEgypt
- Study dates
- 7 Oct 2026to 15 Feb 2027
- Phase
- Interventional
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- patients with single rooted mature permanent teeth
- presence of symptomatic or asymptomatic irreversible pulpitis or apical periodontitis
- medically free patients
Who cannot join
- Teeth with previous root canal treatment teeth with anatomical variations patients who take analgesic or antiinflammatory drugs regularly or just before participation in the study
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site
Faculty of Dentistry, Tanta University
Tanta, Gharbia Governorate, 31527
Tokka Mohamed Mouktar, PHD, +20 1018834376, toka.rady@dent.tanta.edu.eg
About this study
purpose: to evaluate the postoperative pain incidence and intensity after three different obturation techniques (Cold lateral condensation technique (CLC), Vibration thermo-dynamic technique (Vibra-Tho) and Injection of thermo-plasticized gutta-percha (Fast Fill device)). Materials and Methods: Thirty patients with non-vital mature maxillary incisors requiring endodontic treatment will be randomly divided into three groups (n=10) according to the obturation technique used: Group I (CLC), Group II (Vibra-Tho) and Group III (Fast Fill device). Postoperative pain levels will be recorded using the visual Analogue Scale (VAS) immediately post operative and at 24 hours, 72 hours, one week and two weeks.
- Conditions
- Postoperative Pain
- Being tested
- Cold Lateral condensation technique, Vibration thermo-dynamic technique, Injection of thermo-plasticized gutta-percha
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Cold Lateral condensation techniqueProcedure or surgery
Root canal obturation technique
Vibration thermo-dynamic techniqueProcedure or surgery
a device for obturation of root canal
Injection of thermo-plasticized gutta-perchaProcedure or surgery
a device for root canal obturation
| Study group | Role | What they receive |
|---|---|---|
| Cold lateral condensation technique | Experimental | a technique for root canal obturation Receives: Procedure: Cold Lateral condensation technique |
| Vibration thermo-dynamic technique | Experimental | a technique for obturation of root canal Receives: Procedure: Vibration thermo-dynamic technique |
| Injection of thermo-plasticized gutta-percha | Experimental | a technique for obturation of root canal Receives: Procedure: Injection of thermo-plasticized gutta-percha |
What is being measured
The primary outcome is the main question the study is designed to answer.
Postoperative pain
postoperative pain will be evaluated using VAS
Measured: post operative and at 24 hours, 72 hours, one week and two weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2026
- Study start7 Oct 2026 (estimated)
- Primary completion1 Feb 2027 (estimated)
- Study completion15 Feb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tokka Mohamed Moukhtar, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07863622
- Sponsor's protocol ID
- #R-END-8-26-3292
- Status last verified
- Oct 2026
- First submitted
- 2 Oct 2026
- Last updated
- 8 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No