Postoperative PainNCT07863544
Dexmedetomidine vs. Tramadol With Ropivacaine in Ultrasound-Guided PENG Block for Hip Surgery
A study testing Pericapsular nerve group block in people with Postoperative Pain, run by Sargodha Medical College at 1 site in Pakistan.
Trial summary
To compare the mean onset of sensory block and mean time to first rescue analgesia between ropivacaine with dexmedetomidine and ropivacaine with tramadol in ultrasound-guided pericapsular nerve group block for postoperative analgesia in patients undergoing hip surgeries. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Pericapsular nerve group block
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 66 participants
- Where
- 1 sitePakistan
- Study dates
- 10 Oct 2026to 30 Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Patients aged 18 to 65years
- Either gender
- American Society of Anesthesiologists physical status I and II
- Patients undergoing hip surgery under spinal anaesthesia
Who cannot join
- Known allergy to ropivacaine,dexmedetomidine,tramadol,ketorolac or bupivacaine
- Contraindication to spinal anaesthesia or block,such as coagulopathy (INR above 1.5 or platelet count below 100,000/mm3) or local infection at the injection site
- Bilateral,pathological or multiple fractures
- Baseline heart rate below 60 beats per minute,heart block or use of beta blockers
- Serum creatinine above 1.5mg/dL or history of peptic ulcer disease
- History of seizures or use of antidepressants
Show all 9Show fewer
- Cognitive impairment or inability to understand the VAS
- Pregnancy
- Failed block (Hollmen grade below 3 at 30 minutes)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Dr Faisal Masood teaching Hospital Sargodha
Sargodha, Punjab Province, 40100
About this study
Official title: Comparison of Combination of Ropivacaine and Dexmedetomidine Versus Ropivacaine and Tramadol in Ultrasound-guided Pericapsular Nerve Group Block for Postoperative Analgesia in Hip Surgeries.
To compare the mean onset of sensory block and mean time to first rescue analgesia between ropivacaine with dexmedetomidine and ropivacaine with tramadol in ultrasound-guided pericapsular nerve group block for postoperative analgesia in patients undergoing hip surgeries.
- Conditions
- Postoperative Pain
- Being tested
- Pericapsular nerve group block
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pericapsular nerve group blockProcedure or surgery
With the patient supine, a low-frequency curvilinear probe will be placed over the anterior inferior iliac spine and aligned with the superior pubic ramus. The needle will be inserted in-plane,lateral to medial,into the fascial plane between the psoas tendon and the superior pubic ramus,and the drug will be injected after negative aspiration.
| Study group | Role | What they receive |
|---|---|---|
| Ropivacaine and Tramadol | Other | Not described Receives: Procedure: Pericapsular nerve group block |
| Ropivacaine with Dexmedetomidine | Other | Not described Receives: Procedure: Pericapsular nerve group block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Onset of sensory block
Measured: With in 30 minutes
Time to first rescue analgesia
Measured: With in 24 hours
Blood pressure
Measured: With in 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2026
- Study start10 Oct 2026 (estimated)
- Primary completion30 Aug 2027 (estimated)
- Study completion30 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 66 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sargodha Medical College
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07863544
- Sponsor's protocol ID
- SMC-ANS-2026-0003
- Status last verified
- Oct 2026
- First submitted
- 22 Sep 2026
- Last updated
- 7 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Combination of Ropivacaine and Dexmedetomidine Versus Ropivacaine and Tramadol in Ultrasound-guided Pericapsular Nerve Group Block for Postoperative Analgesia in Hip Surgeries.
- ClinicalTrials.gov ID
- NCT07863544
- Acronym / sponsor ID
- SMC-ANS-2026-0003
- Conditions
- Postoperative Pain
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 66 participants (estimated)
- Lead sponsor
- Sargodha Medical CollegeUniversity, hospital or other
- Study start
- 10 Oct 2026 (estimated)
- Primary completion
- 30 Aug 2027 (estimated)
- Study completion
- 30 Aug 2027 (estimated)
- First posted
- 7 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To compare the mean onset of sensory block and mean time to first rescue analgesia between ropivacaine with dexmedetomidine and ropivacaine with tramadol in ultrasound-guided pericapsular nerve group block for postoperative analgesia in patients undergoing hip surgeries.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Ropivacaine and Tramadol | Other | Procedure: Pericapsular nerve group block |
| Ropivacaine with Dexmedetomidine | Other | Procedure: Pericapsular nerve group block |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Patients aged 18 to 65years
- Either gender
- American Society of Anesthesiologists physical status I and II
- Patients undergoing hip surgery under spinal anaesthesia
Key exclusion criteria (9 listed)
- Known allergy to ropivacaine,dexmedetomidine,tramadol,ketorolac or bupivacaine
- Contraindication to spinal anaesthesia or block,such as coagulopathy (INR above 1.5 or platelet count below 100,000/mm3) or local infection at the injection site
- Bilateral,pathological or multiple fractures
- Baseline heart rate below 60 beats per minute,heart block or use of beta blockers
- Serum creatinine above 1.5mg/dL or history of peptic ulcer disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pericapsular nerve group blockWith the patient supine, a low-frequency curvilinear probe will be placed over the anterior inferior iliac spine and aligned with the superior pubic ramus. The needle will be inserted in-plane,lateral to medial,into the fascial plane between the psoas tendon and the superior pubic ramus,and the drug will be injected after negative aspiration. | Procedure or surgery | Ropivacaine and Tramadol, Ropivacaine with Dexmedetomidine |
Primary outcome
Onset of sensory block
Time frame: With in 30 minutes
Time to first rescue analgesia
Time frame: With in 24 hours
Blood pressure
Time frame: With in 24 hours
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pericapsular nerve group block in people with Postoperative Pain, run by Sargodha Medical College at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 7 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Maham Maham Idrees, MBBS, FCPS Anesthesia (03087506429, mahamidrees90009@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Onset of sensory block (time frame: With in 30 minutes). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2026.