Postoperative Pulmonary Complications (PPC)NCT07862777
Geriatric Nutritional Risk Index and ASA Status for Predicting Lung Complications After Major Abdominal Surgery in Older Adults
An observational study of Postoperative Pulmonary Complications (PPC), run by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Postoperative pulmonary complications (PPCs), such as pneumonia, atelectasis, and respiratory failure, are major causes of illness, prolonged hospital stays, and intensive care admissions in older patients undergoing elective major abdominal surgery. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Postoperative Pulmonary Complications (PPC)
- How many people
- 170 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 2 Oct 2026to 1 Aug 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: The study population will consist of adults aged 65 years or older who are scheduled to undergo elective major abdominal surgery under general anesthesia at Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital in Ankara, Turkey. Eligible participants will be enrolled consecutively after informed consent is obtained from the participant or their legal representative. Major procedures may include colorectal surgery, gastrectomy, pancreatic surgery, and major hepatobiliary resection. Patients undergoing emergency or minor surgery, those with active pneumonia or acute respiratory failure before surgery, and those with missing preoperative albumin, weight, or height data will be excluded.
Who may be able to join
- Age 65 years or older.
- Scheduled for elective major abdominal surgery under general anesthesia, including colorectal surgery, gastrectomy, pancreatic surgery, or major hepatobiliary resection.
- American Society of Anesthesiologists Physical Status (ASA-PS) class I, II, III, or IV.
- Informed consent provided by the participant or their legal representative.
Who cannot join
- Emergency surgery.
- Minor or superficial procedures that do not require major intra-abdominal surgery, such as diagnostic laparoscopy, simple laparoscopic cholecystectomy, or simple hernia repair.
- Active pneumonia or acute respiratory failure before surgery.
- Missing preoperative serum albumin, body weight, or height measurements.
- Does not provide informed consent or withdraws from the study.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Dr. Abdurrahman Yurtaslan Ankara Oncology Hospital
Yenimahalle, Ankara, 06370
arif timuroglu, 05072601980, ariftimuroglu@yahoo.com
About this study
Official title: Contribution of the Geriatric Nutritional Risk Index in Addition to the American Society of Anesthesiologists Physical Status Classification for Predicting Postoperative Pulmonary Complications After Elective Major Abdominal Surgery in Geriatric Patients
Postoperative pulmonary complications (PPCs), such as pneumonia, atelectasis, and respiratory failure, are major causes of illness, prolonged hospital stays, and intensive care admissions in older patients undergoing elective major abdominal surgery. The American Society of Anesthesiologists Physical Status (ASA-PS) classification is commonly used before surgery to estimate risk. However, ASA-PS does not directly measure nutritional depletion or muscle weakness, which are critical risk factors in geriatric patients.
The Geriatric Nutritional Risk Index (GNRI) is a simple, objective screening tool calculated from preoperative serum albumin levels and body weight.
The purpose of this observational study is to evaluate the role of GNRI in predicting postoperative pulmonary complications and to determine whether adding GNRI to the standard ASA-PS classification improves the ability to identify older patients at high risk for lung complications after major abdominal surgery.
- Keywords
- Geriatric Nutritional Risk Index, ASA Physical Status, Postoperative Pulmonary Complications, Elective Major Abdominal Surgery
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Older Adults Undergoing Elective Major Abdominal Surgery | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incidence of Postoperative Pulmonary Complications Within 30 Days
The proportion of participants who develop at least one postoperative pulmonary complication within 30 days after surgery. Complications, including pneumonia, atelectasis, respiratory failure, or reintubation, will be identified according to the European Perioperative Clinical Outcome (EPCO) consensus definitions using hospital records and the planned 30-day follow-up.
Measured: From the date of surgery through postoperative day 30.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Oct 2026
- Study start2 Oct 2026
- Primary completion1 Jul 2027 (estimated)
- Study completion1 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Postoperative Pulmonary Complications (PPC)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 170 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Arif Timuroğlu, MD, Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Investigators
- arif timuroglu, Principal investigator, Dr. Abdurrahman yurtaslan Ankara Oncology Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07862777
- Sponsor's protocol ID
- 2026-09/215
- Status last verified
- Oct 2026
- First submitted
- 2 Oct 2026
- Last updated
- 7 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be publicly shared to protect participant confidentiality and comply with institutional and local ethical approval restrictions. Aggregated data and study findings will be available within the published manuscript and supplementary files.
Study at a glance
From the registry record, last updated by the sponsor on 7 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Contribution of the Geriatric Nutritional Risk Index in Addition to the American Society of Anesthesiologists Physical Status Classification for Predicting Postoperative Pulmonary Complications After Elective Major Abdominal Surgery in Geriatric Patients
- ClinicalTrials.gov ID
- NCT07862777
- Acronym / sponsor ID
- 2026-09/215
- Keywords
- Geriatric Nutritional Risk Index, ASA Physical Status, Postoperative Pulmonary Complications, Elective Major Abdominal Surgery
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 170 participants (estimated)
- Lead sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research HospitalUniversity, hospital or other
- Study start
- 2 Oct 2026 (actual)
- Primary completion
- 1 Jul 2027 (estimated)
- Study completion
- 1 Aug 2027 (estimated)
- First posted
- 7 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Postoperative pulmonary complications (PPCs), such as pneumonia, atelectasis, and respiratory failure, are major causes of illness, prolonged hospital stays, and intensive care admissions in older patients undergoing elective major abdominal surgery. The American Society of Anesthesiologists Physical Status (ASA-PS) classification is commonly used before surgery to estimate risk. However, ASA-PS does not directly measure nutritional depletion or muscle weakness, which are critical risk factors in geriatric patients.
The Geriatric Nutritional Risk Index (GNRI) is a simple, objective screening tool calculated from preoperative serum albumin levels and body weight.
The purpose of this observational study is to evaluate the role of GNRI in predicting postoperative pulmonary complications and to determine whether adding GNRI to the standard ASA-PS classification improves the ability to identify older patients at high risk for lung complications after major abdominal surgery.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Older Adults Undergoing Elective Major Abdominal Surgery | – | – |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- The study population will consist of adults aged 65 years or older who are scheduled to undergo elective major abdominal surgery under general anesthesia at Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital in Ankara, Turkey. Eligible participants will be enrolled consecutively after informed consent is obtained from the participant or their legal representative. Major procedures may include colorectal surgery, gastrectomy, pancreatic surgery, and major hepatobiliary resection. Patients undergoing emergency or minor surgery, those with active pneumonia or acute respiratory failure before surgery, and those with missing preoperative albumin, weight, or height data will be excluded.
Key inclusion criteria (4 listed)
- Age 65 years or older.
- Scheduled for elective major abdominal surgery under general anesthesia, including colorectal surgery, gastrectomy, pancreatic surgery, or major hepatobiliary resection.
- American Society of Anesthesiologists Physical Status (ASA-PS) class I, II, III, or IV.
- Informed consent provided by the participant or their legal representative.
Key exclusion criteria (5 listed)
- Emergency surgery.
- Minor or superficial procedures that do not require major intra-abdominal surgery, such as diagnostic laparoscopy, simple laparoscopic cholecystectomy, or simple hernia repair.
- Active pneumonia or acute respiratory failure before surgery.
- Missing preoperative serum albumin, body weight, or height measurements.
- Does not provide informed consent or withdraws from the study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Incidence of Postoperative Pulmonary Complications Within 30 Days
Time frame: From the date of surgery through postoperative day 30.
The proportion of participants who develop at least one postoperative pulmonary complication within 30 days after surgery. Complications, including pneumonia, atelectasis, respiratory failure, or reintubation, will be identified according to the European Perioperative Clinical Outcome (EPCO) consensus definitions using hospital records and the planned 30-day follow-up.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Oct 2026.
- Individual participant dataSharing planned: No. Individual participant data will not be publicly shared to protect participant confidentiality and comply with institutional and local ethical approval restrictions. Aggregated data and study findings will be available within the published manuscript and supplementary files.
Related trials for Postoperative Pulmonary Complications (PPC)
Not yet recruiting
Postoperative Pulmonary Complications After Use of Supraglottic Airway Devices and Neuromuscular Blockade
Postoperative Pulmonary Complications
Not yet recruiting
High-Flow Nasal Cannula After Major Abdominal Surgery to Prevent Postoperative Pulmonary Complications
Postoperative Complications, Atelectasis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
arif timuroglu principal investigator
Dr. Abdurrahman yurtaslan Ankara Oncology Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Postoperative Pulmonary Complications (PPC), run by Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact arif timuroglu, MD (05072601980, ariftimuroglu@yahoo.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incidence of Postoperative Pulmonary Complications Within 30 Days (time frame: From the date of surgery through postoperative day 30.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Oct 2026.