Difficult IntubationMEGRINCT07857395
Modified El-Ganzouri Risk Index for Predicting Difficult Intubation in Obese Patients
An observational study of Difficult Intubation and Obesity, run by Zagazig University at 1 site in Egypt.
Trial summary
This observational study aims to compare the predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) incorporating anthropometric ratios with the original El-Ganzouri Risk Index (EGRI) for predicting difficult intubation in obese adult patients undergoing elective general anesthesia. Read more about this study
- Who is it for?
- Ages 21 to 65 years
- Conditions the study is for
- Difficult Intubation, Obesity
- How many people
- 114 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Oct 2026to 31 Mar 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Age: 21-65 years old.ASA: II,III.Obese patients (Body Mass Index (BMI) 30-40 kg/m² ) scheduled for elective surgical procedures under general anesthesia
Who may be able to join
- Patient acceptance.
- Age: 21-65 years old.
- ASA: II,III.
- Obese patients (Body Mass Index (BMI) 30-40 kg/m² ) scheduled for elective surgical procedures under general anesthesia
Who cannot join
- Patients undergoing maxillofacial trauma surgery.
- Patients with a history of neck surgery or cervical spine instability.
- Pregnant patients, and those requiring rapid sequence intubation.
- Upper airway pathology or surgery.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: A Trial to Modify the El-Ganzouri Risk Index by Incorporating Anthropometric Ratios for Predicting Difficult Intubation in Obese Patients Undergoing General Anesthesia
This observational study aims to compare the predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) incorporating anthropometric ratios with the original El-Ganzouri Risk Index (EGRI) for predicting difficult intubation in obese adult patients undergoing elective general anesthesia.
- Conditions
- Difficult Intubation, Obesity
- Being tested
- No intervention
- Keywords
- El-Ganzouri Risk Index Modified El-Ganzouri Risk Index MEGRI Difficult Laryngoscopy Difficult Tracheal Intubation Anthropometric Ratios
- Medical subject headings
- Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
No interventionOther
This is an observational study. No study intervention is assigned. Patients receive standard anesthetic care, and preoperative airway assessment and intraoperative intubation outcomes are recorded for comparison of the original and Modified El-Ganzouri Risk Index.
| Study group | Role | What they receive |
|---|---|---|
| Obese Adult Patients | Adult obese patients undergoing elective general anesthesia who will be assessed preoperatively using both the original El-Ganzouri Risk Index and the Modified El-Ganzouri Risk Index, followed by assessment of laryngoscopy and intubation outcomes. Receives: Other: No intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Area Under the Receiver Operating Characteristic Curve (AUC) of the Modified El-Ganzouri Risk Index for Predicting Difficult Intubation
The predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) for difficult intubation will be evaluated using receiver operating characteristic (ROC) curve analysis and the area under the curve (AUC).
Measured: From preoperative airway assessment to completion of endotracheal intubation during surgery.
Secondary outcomes (1)
Area Under the Receiver Operating Characteristic Curve (AUC) of the Original El-Ganzouri Risk Index for Predicting Difficult Intubation
The predictive performance of the original El-Ganzouri Risk Index (EGRI) for difficult intubation will be evaluated using receiver operating characteristic (ROC) curve analysis and the area under the curve (AUC).
Measured: From preoperative airway assessment to completion of endotracheal intubation during surgery.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Oct 2026
- Study start1 Oct 2026 (estimated)
- Primary completion31 Mar 2027 (estimated)
- Study completion31 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Difficult IntubationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 114 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Zagazig University
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Islam Ramzy Ahmed Ali, Zagazig University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07857395
- Sponsor's protocol ID
- 2646/13-9-2026
- Acronym
- MEGRI
- Status last verified
- Oct 2026
- First submitted
- 26 Sep 2026
- Last updated
- 5 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Trial to Modify the El-Ganzouri Risk Index by Incorporating Anthropometric Ratios for Predicting Difficult Intubation in Obese Patients Undergoing General Anesthesia
- ClinicalTrials.gov ID
- NCT07857395
- Acronym / sponsor ID
- MEGRI / 2646/13-9-2026
- Conditions
- Difficult Intubation, Obesity
- Keywords
- El-Ganzouri Risk Index Modified El-Ganzouri Risk Index MEGRI Difficult Laryngoscopy Difficult Tracheal Intubation Anthropometric Ratios
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 114 participants (estimated)
- Lead sponsor
- Zagazig UniversityOther government
- Study start
- 1 Oct 2026 (estimated)
- Primary completion
- 31 Mar 2027 (estimated)
- Study completion
- 31 Mar 2027 (estimated)
- First posted
- 5 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study aims to compare the predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) incorporating anthropometric ratios with the original El-Ganzouri Risk Index (EGRI) for predicting difficult intubation in obese adult patients undergoing elective general anesthesia.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Obese Adult Patients | – | Other: No interventionAdult obese patients undergoing elective general anesthesia who will be assessed preoperatively using both the original El-Ganzouri Risk Index and the Modified El-Ganzouri Risk Index, followed by assessment of laryngoscopy and intubation outcomes. |
Who may qualify
- Ages
- 21 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Age: 21-65 years old.ASA: II,III.Obese patients (Body Mass Index (BMI) 30-40 kg/m² ) scheduled for elective surgical procedures under general anesthesia
Key inclusion criteria (4 listed)
- Patient acceptance.
- Age: 21-65 years old.
- ASA: II,III.
- Obese patients (Body Mass Index (BMI) 30-40 kg/m² ) scheduled for elective surgical procedures under general anesthesia
Key exclusion criteria (4 listed)
- Patients undergoing maxillofacial trauma surgery.
- Patients with a history of neck surgery or cervical spine instability.
- Pregnant patients, and those requiring rapid sequence intubation.
- Upper airway pathology or surgery.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| No interventionThis is an observational study. No study intervention is assigned. Patients receive standard anesthetic care, and preoperative airway assessment and intraoperative intubation outcomes are recorded for comparison of the original and Modified El-Ganzouri Risk Index. | Other | Obese Adult Patients |
Primary outcome
Area Under the Receiver Operating Characteristic Curve (AUC) of the Modified El-Ganzouri Risk Index for Predicting Difficult Intubation
Time frame: From preoperative airway assessment to completion of endotracheal intubation during surgery.
The predictive performance of the Modified El-Ganzouri Risk Index (MEGRI) for difficult intubation will be evaluated using receiver operating characteristic (ROC) curve analysis and the area under the curve (AUC).
1 secondary outcome
Area Under the Receiver Operating Characteristic Curve (AUC) of the Original El-Ganzouri Risk Index for Predicting Difficult Intubation
Time frame: From preoperative airway assessment to completion of endotracheal intubation during surgery.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Difficult Intubation and Obesity, run by Zagazig University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 5 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Eslam Ramzy Ahmed (+201551210896, eslameljarrah@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Area Under the Receiver Operating Characteristic Curve (AUC) of the Modified El-Ganzouri Risk Index for Predicting Difficult Intubation (time frame: From preoperative airway assessment to completion of endotracheal intubation during surgery.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Oct 2026.