Adenoid HypertrophyNCT07856771
Conventional Curettage Versus Endoscopic Microdebrider-Assisted Adenoidectomy in Children
A study testing Conventional Curretage Adenoidectomy and Endoscopic Microdebrider-Assisted Adenoidectomy in people with Adenoid Hypertrophy, run by Allama Iqbal Teaching Hospital at 1 site in Pakistan.
Trial summary
The purpose of this randomized clinical trial is to compare two surgical methods for removing enlarged adenoids in children: conventional curettage adenoidectomy and endoscopic microdebrider-assisted adenoidectomy. Read more about this study
- Who is it for?
- Ages 3 to 16 years
- Conditions the study is for
- Adenoid Hypertrophy
- What is being tested?
- Conventional Curretage Adenoidectomy and Endoscopic Microdebrider-Assisted Adenoidectomy
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 88 participants
- Where
- 1 sitePakistan
- Study dates
- 1 May 2025to 30 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 3 to 16 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
None listed.
Who cannot join
- Craniofacial syndromes (cleft lip, cleft palate)
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Allama Iqbal Teaching Hospital
Dera Ghazi Khan, Punjab Province, 32200
About this study
Official title: A Comparative Study of Conventional Curettage Adenoidectomy Versus Endoscopic Microdebrider-Assisted Adenoidectomy in Children
The purpose of this randomized clinical trial is to compare two surgical methods for removing enlarged adenoids in children: conventional curettage adenoidectomy and endoscopic microdebrider-assisted adenoidectomy. Enlarged adenoids can cause problems such as snoring, mouth breathing, obstructive sleep apnea, and changes in facial appearance.
The main question this study aims to answer is:
Read more
- Does endoscopic microdebrider-assisted adenoidectomy result in different operative outcomes compared with conventional curettage adenoidectomy?
The study will include 88 children aged 3-16 years who have enlarged adenoids and symptoms such as obstructive sleep apnea, mouth breathing, or snoring. Participants will be randomly assigned to one of two groups:
- Group A: Adenoidectomy using a conventional adenoid curette.
- Group B: Adenoidectomy using a microdebrider while viewing the adenoids with an endoscope.
All procedures will be performed under general anesthesia. The researchers will record the duration of the operation and the amount of blood lost during surgery. These outcomes will be compared between the two groups to determine whether the surgical techniques differ in operative time and blood loss.
Parents or guardians will provide informed consent before their child participates in the study.
- Conditions
- Adenoid Hypertrophy
- Being tested
- Conventional Curretage Adenoidectomy, Endoscopic Microdebrider-Assisted Adenoidectomy
- Keywords
- Adenoidectomy, Adenoid Hypertrophy, Endoscopic Adenoidectomy, Microdebrider, Curettage Adenoidectomy, Pediatric Adenoidectomy, Obstructive Sleep Apnea, Snoring, Mouth Breathing, Operative time, Blood loss
- Medical subject headings
- Sleep Apnea, Obstructive, Snoring, Mouth Breathing, Hemorrhage
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Conventional Curretage AdenoidectomyProcedure or surgery
Surgical removal of enlarged adenoid tissue using a St. Clair Thompson adenoid curette under general anesthesia with orotracheal intubation.
Endoscopic Microdebrider-Assisted AdenoidectomyProcedure or surgery
A 45° angled blade will be introduced through the oropharynx, with irrigation at 15 mL/min and the microdebrider set at 5000 oscillations/second. A zero-degree endoscope will be inserted through either nostril for visualization during the procedure.
| Study group | Role | What they receive |
|---|---|---|
| Conventional Curretage Adenoidectomy | Active comparator | Participants will undergo conventional adenoidectomy using a St. Clair Thompson adenoid curette under general anesthesia with orotracheal intubation. Receives: Procedure: Conventional Curretage Adenoidectomy |
| Endoscopic Microdebrider-Assisted Adenoidectomy | Experimental | Participants will undergo adenoidectomy using a microdebrider under endoscopic visualization. Receives: Procedure: Endoscopic Microdebrider-Assisted Adenoidectomy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Intraoperative Blood Loss
Total blood loss during adenoidectomy, measured from the graduated suction cylinder and by weighing pre-weighed roller packs used in the nasopharynx, with 1 gram of blood equivalent to 1 mL.
Measured: From the start of surgery until completion of adenoidectomy and handover of the patient to the anesthetist for extubation.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Oct 2026
- Study start1 May 2025
- Primary completion30 Oct 2025
- Study completion30 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Adenoid HypertrophyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 88 participants (actual)
Sponsor and investigators
- Lead sponsor
- Allama Iqbal Teaching Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Hasham Wahid, Allama Iqbal Teaching Hospital
- Investigators
- Muhammad W Saleem, FCPS, Study chair, Allama Iqbal Teaching Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07856771
- Sponsor's protocol ID
- U1111-1347-4945
- Status last verified
- Sep 2026
- First submitted
- 28 Sep 2026
- Last updated
- 5 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Comparative Study of Conventional Curettage Adenoidectomy Versus Endoscopic Microdebrider-Assisted Adenoidectomy in Children
- ClinicalTrials.gov ID
- NCT07856771
- Acronym / sponsor ID
- U1111-1347-4945
- Conditions
- Adenoid Hypertrophy
- Keywords
- Adenoidectomy, Adenoid Hypertrophy, Endoscopic Adenoidectomy, Microdebrider, Curettage Adenoidectomy, Pediatric Adenoidectomy, Obstructive Sleep Apnea, Snoring
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 88 participants (actual)
- Lead sponsor
- Allama Iqbal Teaching HospitalOther government
- Study start
- 1 May 2025 (actual)
- Primary completion
- 30 Oct 2025 (actual)
- Study completion
- 30 Oct 2025 (actual)
- First posted
- 5 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this randomized clinical trial is to compare two surgical methods for removing enlarged adenoids in children: conventional curettage adenoidectomy and endoscopic microdebrider-assisted adenoidectomy. Enlarged adenoids can cause problems such as snoring, mouth breathing, obstructive sleep apnea, and changes in facial appearance.
The main question this study aims to answer is:
- Does endoscopic microdebrider-assisted adenoidectomy result in different operative outcomes compared with conventional curettage adenoidectomy?
The study will include 88 children aged 3-16 years who have enlarged adenoids and symptoms such as obstructive sleep apnea, mouth breathing, or snoring. Participants will be randomly assigned to one of two groups:
- Group A: Adenoidectomy using a conventional adenoid curette.
- Group B: Adenoidectomy using a microdebrider while viewing the adenoids with an endoscope.
All procedures will be performed under general anesthesia. The researchers will record the duration of the operation and the amount of blood lost during surgery. These outcomes will be compared between the two groups to determine whether the surgical techniques differ in operative time and blood loss.
Parents or guardians will provide informed consent before their child participates in the study.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Conventional Curretage Adenoidectomy | Active comparator | Procedure: Conventional Curretage AdenoidectomyParticipants will undergo conventional adenoidectomy using a St. Clair Thompson adenoid curette under general anesthesia with orotracheal intubation. |
| Endoscopic Microdebrider-Assisted Adenoidectomy | Experimental | Procedure: Endoscopic Microdebrider-Assisted AdenoidectomyParticipants will undergo adenoidectomy using a microdebrider under endoscopic visualization. |
Who may qualify
- Ages
- 3 to 16 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (0 listed)
Key exclusion criteria (1 listed)
- Craniofacial syndromes (cleft lip, cleft palate)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Conventional Curretage AdenoidectomySurgical removal of enlarged adenoid tissue using a St. Clair Thompson adenoid curette under general anesthesia with orotracheal intubation. | Procedure or surgery | Conventional Curretage Adenoidectomy |
| Endoscopic Microdebrider-Assisted AdenoidectomyA 45° angled blade will be introduced through the oropharynx, with irrigation at 15 mL/min and the microdebrider set at 5000 oscillations/second. A zero-degree endoscope will be inserted through either nostril for visualization during the procedure. | Procedure or surgery | Endoscopic Microdebrider-Assisted Adenoidectomy |
Primary outcome
Intraoperative Blood Loss
Time frame: From the start of surgery until completion of adenoidectomy and handover of the patient to the anesthetist for extubation.
Total blood loss during adenoidectomy, measured from the graduated suction cylinder and by weighing pre-weighed roller packs used in the nasopharynx, with 1 gram of blood equivalent to 1 mL.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Muhammad W Saleem, FCPS study chair
Allama Iqbal Teaching Hospital
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Conventional Curretage Adenoidectomy and Endoscopic Microdebrider-Assisted Adenoidectomy in people with Adenoid Hypertrophy, run by Allama Iqbal Teaching Hospital at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 0 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Intraoperative Blood Loss (time frame: From the start of surgery until completion of adenoidectomy and handover of the patient to the anesthetist for extubation.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Oct 2026.