Comparative Study Between Erector Spinae Plane Block Versus Combined Pectoralis and Serratus Interfascial Plane Blocks for Post-operative Analgesia After Thoracic Surgery.

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

• Ages 18 to 70 years
• All sexes
• No healthy volunteers
• Adult, Older adult

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

About this study

Official title: Randomized Controlled Double Blinded Comparative Study Between Erector Spinae Plane Block Versus Combined Pectoralis and Serratus Interfascial Plane Blocks for Post-operative Analgesia After Thoracic Surgery.

Conditions

Post Operative Pain, Thoracic Surgery

Being tested

Erector spinae plane block, Combined pectoralis and serratus anterior plane blocks

Keywords

Nerve block in thoracic surgery

Medical subject headings

Pain, Postoperative

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

• Erector spinae plane blockProcedure or surgery

  Also called ESPB

  Patients will be positioned in the lateral position, The thoracic vertebrae spinous process convenient to level of incision (T5-T7:the level which covers thoracic area) will be identified and the transducer will be placed approximately to 2-3 cm lateral to midline ,The needle tip will be advanced until it is located in the interfascial plane deep to the erector spinae muscle group and superior to the transverse process. Once in position, 30 ml bupivacaine 0.25% will be injected under ultrasound guidance. Correct needle-tip position will be confirmed by the presence of linear spread between the transverse process and the presence of linear spread between the transverse process and the erector spinae muscle group.

• Combined pectoralis and serratus anterior plane blocksProcedure or surgery

  Also called PECS &SAPB

  Serratus anterior plane block will be performed with the patient in the supine position , The probe will be placed in a sagittal position, the mid-axillary region of the thoracic cage. The needle will be advanced with an in-plane technique and 20 ml bupivacaine 0.25% will be injected .

  PECS block will be performed at the same position. The ultrasound probe will be placed obliquely over the lateral third of the clavicle. the needle will be advanced, in the same plane as the probe, from the medial to lateral direction ,10 ml 0.25% bupivacaine will be injected. Then the needle will be advanced to the fascial plane between the pectoralis minor and serratus anterior muscles, at which point an additional 10 ml 0.25% bupivacaine will be administered.

What is being measured

The primary outcome is the main question the study is designed to answer.

1. First analgesic request

   The time of first request to analgesia by patient post operative

   Measured: 24 hours

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1. First posted2 Oct 2026
2. Study start1 Apr 2025
3. Primary completionNov 2026 (estimated)
4. Study completionNov 2026 (estimated)

Resources

• Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
• Other trials for Post Operative PainStudies of the same condition, open and under way.
• What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.