Deep Bite MalocclusionNCT07851948

Effects of Anterior Bite Turbos on Deep Bite Treatment and Chewing Muscles

A study testing Anterior Bite Turbo and Fixed Orthodontic Treatment in people with Deep Bite Malocclusion, run by Ankara University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

Who is it for?: Any ageHealthy volunteers can take part
Conditions the study is for: Deep Bite Malocclusion
What is being tested?: Anterior Bite Turbo and Fixed Orthodontic Treatment
Type of treatment: Medical device, Surgery or procedure
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 28 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 20 Oct 2025to 28 Aug 2026
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages Any age
All sexes
Healthy volunteers accepted
Child, Adult, Older adult

Who may be able to join

Permanent dentition.
Angle Class I or Class II malocclusion.
Mild to moderate dental crowding (≤6 mm).
Non-extraction fixed orthodontic treatment planned.
No missing teeth, excluding third molars.
For the anterior bite turbo group: increased overbite (>4 mm).
For the control group: normal anterior overbite (2-3 mm).

Who cannot join

Bruxism or other oral parafunctional habits.
Temporomandibular joint disorder.
Craniofacial asymmetry, craniofacial syndrome, or cleft lip and/or palate.
Dental anomalies, including missing teeth other than third molars or abnormalities of tooth shape.
Previous orthodontic or myofunctional treatment.

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

Ankara University, Faculty of Dentistry, Department of Orthodontics
Ankara, 06560

Other trials in Turkey (Türkiye)

About this study

Official title: Evaluation of the Effects of Anterior Bite Turbo Application During Deep Bite Treatment on Dentoalveolar and Skeletal Structures and Masticatory Muscles

This study evaluated how anterior bite turbos used during orthodontic treatment of deep bite affect chewing muscle activity and dental and skeletal measurements. Participants were followed in two nonrandomized groups: one received anterior bite turbos as part of orthodontic treatment, and the other received orthodontic treatment without bite turbos. Surface electromyography (EMG) was used to measure muscle activity over time. Cephalometric measurements were also evaluated to assess treatment-related changes.

Read the detailed description

This prospective, nonrandomized, two-group study examined patients undergoing orthodontic treatment for deep bite. Anterior bite turbos were applied in one group; the comparison group underwent orthodontic treatment without anterior bite turbos during the study period.

Surface EMG recordings of the right and left masseter, anterior temporalis, and anterior digastric muscles were obtained at rest and during maximum voluntary clenching. Both groups were assessed before treatment, at approximately one month, and at approximately six months. The bite turbo group also underwent an EMG assessment immediately after bite turbo placement. Cephalometric measurements were evaluated at baseline and approximately six months.

Conditions: Deep Bite Malocclusion
Being tested: Anterior Bite Turbo, Fixed Orthodontic Treatment
Keywords: Anterior bite turbo, Surface electromyography, Deep overbite, Masticatory muscles, Orthodontic treatment
Medical subject headings: Overbite

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Anterior Bite TurboDevice
Composite resin bite turbos were bonded to the palatal surfaces of the maxillary central incisors during fixed orthodontic treatment. The bite turbos were used to disclude the posterior teeth during deep bite treatment.
Fixed Orthodontic TreatmentProcedure or surgery
Participants received fixed orthodontic treatment for deep bite.

Study groups in NCT07851948
Study group	Role	What they receive
Anterior Bite Turbo Group	Experimental	Participants received anterior bite turbos as part of fixed orthodontic treatment for deep bite. Surface EMG and orthodontic measurements were obtained during follow-up. Receives: Device: Anterior Bite Turbo; Procedure: Fixed Orthodontic Treatment
No Bite Turbo Group	Active comparator	Participants received fixed orthodontic treatment without anterior bite turbos during the study period. Surface EMG and orthodontic measurements were obtained during follow-up. Receives: Procedure: Fixed Orthodontic Treatment

What is being measured

The primary outcome is the main question the study is designed to answer.

Change in Mean Bilateral Masseter Muscle Activity at Rest
Surface electromyographic activity of the right and left masseter muscles was recorded at rest. The mean of the two sides, measured in microvolts (µV), was evaluated at baseline, 1 month, and 6 months. Changes over time were compared between the anterior bite turbo and no bite turbo groups.
Measured: Baseline (before bite turbo placement), 1 month, and 6 months
Change in Mean Bilateral Anterior Digastric Muscle Activity During Maximum Voluntary Clenching
Surface EMG amplitude of the right and left anterior digastric muscles during maximum voluntary clenching was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Measured: Baseline (T0), 1 month (T2), and 6 months (T3).
Change in Mean Bilateral Anterior Digastric Muscle Activity at Rest
Surface EMG amplitude of the right and left anterior digastric muscles at rest was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Measured: Baseline (T0), 1 month (T2), and 6 months (T3).
Change in Mean Bilateral Anterior Temporalis Muscle Activity During Maximum Voluntary Clenching
Surface EMG amplitude of the right and left anterior temporalis muscles during maximum voluntary clenching was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Measured: Baseline (T0), 1 month (T2), and 6 months (T3).
Change in Mean Bilateral Anterior Temporalis Muscle Activity at Rest
Surface EMG amplitude of the right and left anterior temporalis muscles at rest was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Measured: Baseline (T0), 1 month (T2), and 6 months (T3).
Change in Mean Bilateral Masseter Muscle Activity During Maximum Voluntary Clenching
Surface EMG amplitude of the right and left masseter muscles during maximum voluntary clenching was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Measured: Baseline (T0), 1 month (T2), and 6 months (T3).

Secondary outcomes (11)

Change in Overbite
Vertical overlap of the maxillary and mandibular central incisors was measured on lateral cephalograms in millimeters (mm). Change from baseline to 6 months was compared between groups.
Measured: Baseline and 6 months.
Change in Overjet
Horizontal distance between the maxillary and mandibular central incisors was measured on lateral cephalograms in millimeters (mm). Change was compared between groups.
Measured: Baseline and 6 months.
Change in SN-GoGn Angle
The angle between the Sella-Nasion and mandibular planes was measured on lateral cephalograms in degrees. Change was compared between groups.
Measured: Baseline and 6 months.
Change in Overbite
The distance from anterior nasal spine to Menton was measured on lateral cephalograms in millimeters (mm). Change was compared between groups.
Measured: Baseline and 6 months.
Change in ANB Angle
The A point-Nasion-B point angle was measured on lateral cephalograms in degrees. Change was compared between groups.
Measured: Baseline and 6 months.
Change in Upper Incisor to NA Distance
The linear distance from the maxillary central incisor to the Nasion-A point line was measured in millimeters (mm). Change was compared between groups.
Measured: Baseline and 6 months.
Change in Upper Incisor to NA Angle
The angle between the maxillary central incisor long axis and the Nasion-A point line was measured in degrees. Change was compared between groups.
Measured: Baseline and 6 months.
Change in IMPA
The angle between the mandibular central incisor long axis and mandibular plane was measured in degrees. Change was compared between groups.
Measured: Baseline and 6 months.
Change in Interincisal Angle
The angle between the long axes of the maxillary and mandibular central incisors was measured in degrees. Change was compared between groups.
Measured: Baseline and 6 months
Change in Upper Lip to S Line Distance
The distance from the upper lip to Steiner's S line was measured in millimeters (mm). Change was compared between groups.
Measured: Baseline and 6 months
Change in Lower Lip to S Line Distance
The distance from the lower lip to Steiner's S line was measured in millimeters (mm). Change was compared between groups.
Measured: Baseline and 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

20 Oct 202528 Aug 2026

First posted1 Oct 2026
Study start20 Oct 2025
Primary completion28 Aug 2026
Study completion28 Aug 2026

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (2)Papers the sponsor has linked to this study.
Other trials for Deep Bite MalocclusionStudies of the same condition, open and under way.
More trials run by Ankara UniversityThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Non-randomised
Intervention model: Parallel groups
Model description: Participants were followed in two parallel, nonrandomized groups. One group received anterior bite turbos during orthodontic treatment; the comparison group received orthodontic treatment without anterior bite turbos during the study period.
Masking: None (open label)
Enrolment: 28 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07851948
Sponsor's protocol ID: 2025-755
Status last verified: Sep 2026
First submitted: 25 Sep 2026
Last updated: 1 Oct 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No: There is currently no plan to share individual participant data with other researchers.

Publications

Al-Zoubi EM, Al-Nimri KS. A comparative study between the effect of reverse curve of Spee archwires and anterior bite turbos in the treatment of deep overbite cases. Angle Orthod. 2022 Jan 1;92(1):36-44. doi: 10.2319/020921-117.1.
PubMed 34329389
Wasinwasukul P, Nalamliang N, Pairatchawan N, Thongudomporn U. Effects of anterior bite planes fabricated from acrylic resin and thermoplastic material on masticatory muscle responses and maximum bite force in children with a deep bite: A 6-month randomised controlled trial. J Oral Rehabil. 2022 Oct;49(10):980-992. doi: 10.1111/joor.13351. Epub 2022 Jul 3.
PubMed 35730261

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

Recruiting
Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion
Class II Malocclusion
Recruiting
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Malocclusion, Class II Malocclusion
Enrolling by invitationObservational study
Long-term Stability of Treatment With the Twin Block Appliance
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Active, not recruitingObservational study
Comparative Evaluation of Functional and Aesthetic Outcomes of Box and Mini-Wing Genioplasty Techniques
Class II Malocclusion, Dentofacial Deformities
Active, not recruiting
Modified Versus Clear Twin Block for Skeletal Class II Malocclusion
Skeletal Class II Malocclusion

All Deep Bite Malocclusion trials

Study at a glance

From the registry record, last updated by the sponsor on 1 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Evaluation of the Effects of Anterior Bite Turbo Application During Deep Bite Treatment on Dentoalveolar and Skeletal Structures and Masticatory Muscles
ClinicalTrials.gov ID: NCT07851948
Acronym / sponsor ID: 2025-755
Conditions: Deep Bite Malocclusion
Keywords: Anterior bite turbo, Surface electromyography, Deep overbite, Masticatory muscles, Orthodontic treatment
Study type: Interventional
Recruitment status: Completed
Enrolment: 28 participants (actual)
Lead sponsor: Ankara UniversityUniversity, hospital or other
Study start: 20 Oct 2025 (actual)
Primary completion: 28 Aug 2026 (actual)
Study completion: 28 Aug 2026 (actual)
First posted: 1 Oct 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Study design

Primary purpose: Treatment
Allocation: Non-randomised
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2
Model description: Participants were followed in two parallel, nonrandomized groups. One group received anterior bite turbos during orthodontic treatment; the comparison group received orthodontic treatment without anterior bite turbos during the study period.

Arm	Type	Receives
Anterior Bite Turbo Group	Experimental	Device: Anterior Bite Turbo, Procedure: Fixed Orthodontic TreatmentParticipants received anterior bite turbos as part of fixed orthodontic treatment for deep bite. Surface EMG and orthodontic measurements were obtained during follow-up.
No Bite Turbo Group	Active comparator	Procedure: Fixed Orthodontic TreatmentParticipants received fixed orthodontic treatment without anterior bite turbos during the study period. Surface EMG and orthodontic measurements were obtained during follow-up.

Who may qualify

Sex: All
Healthy volunteers: Accepted
Age groups: Child, Adult, Older adult

Key inclusion criteria (7 listed)

Permanent dentition.
Angle Class I or Class II malocclusion.
Mild to moderate dental crowding (≤6 mm).
Non-extraction fixed orthodontic treatment planned.
No missing teeth, excluding third molars.

Key exclusion criteria (5 listed)

Bruxism or other oral parafunctional habits.
Temporomandibular joint disorder.
Craniofacial asymmetry, craniofacial syndrome, or cleft lip and/or palate.
Dental anomalies, including missing teeth other than third molars or abnormalities of tooth shape.
Previous orthodontic or myofunctional treatment.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Anterior Bite TurboComposite resin bite turbos were bonded to the palatal surfaces of the maxillary central incisors during fixed orthodontic treatment. The bite turbos were used to disclude the posterior teeth during deep bite treatment.	Device	Anterior Bite Turbo Group
Fixed Orthodontic TreatmentParticipants received fixed orthodontic treatment for deep bite.	Procedure or surgery	Anterior Bite Turbo Group, No Bite Turbo Group

Primary outcome

Change in Mean Bilateral Masseter Muscle Activity at Rest
Time frame: Baseline (before bite turbo placement), 1 month, and 6 months
Surface electromyographic activity of the right and left masseter muscles was recorded at rest. The mean of the two sides, measured in microvolts (µV), was evaluated at baseline, 1 month, and 6 months. Changes over time were compared between the anterior bite turbo and no bite turbo groups.
Change in Mean Bilateral Anterior Digastric Muscle Activity During Maximum Voluntary Clenching
Time frame: Baseline (T0), 1 month (T2), and 6 months (T3).
Surface EMG amplitude of the right and left anterior digastric muscles during maximum voluntary clenching was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Change in Mean Bilateral Anterior Digastric Muscle Activity at Rest
Time frame: Baseline (T0), 1 month (T2), and 6 months (T3).
Surface EMG amplitude of the right and left anterior digastric muscles at rest was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Change in Mean Bilateral Anterior Temporalis Muscle Activity During Maximum Voluntary Clenching
Time frame: Baseline (T0), 1 month (T2), and 6 months (T3).
Surface EMG amplitude of the right and left anterior temporalis muscles during maximum voluntary clenching was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Change in Mean Bilateral Anterior Temporalis Muscle Activity at Rest
Time frame: Baseline (T0), 1 month (T2), and 6 months (T3).
Surface EMG amplitude of the right and left anterior temporalis muscles at rest was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.
Change in Mean Bilateral Masseter Muscle Activity During Maximum Voluntary Clenching
Time frame: Baseline (T0), 1 month (T2), and 6 months (T3).
Surface EMG amplitude of the right and left masseter muscles during maximum voluntary clenching was averaged for each participant and measured in microvolts (µV). Change over time was compared between groups.

11 secondary outcomes

Change in Overbite
Time frame: Baseline and 6 months.
Change in Overjet
Time frame: Baseline and 6 months.
Change in SN-GoGn Angle
Time frame: Baseline and 6 months.
Change in Overbite
Time frame: Baseline and 6 months.
Change in ANB Angle
Time frame: Baseline and 6 months.
Change in Upper Incisor to NA Distance
Time frame: Baseline and 6 months.
Change in Upper Incisor to NA Angle
Time frame: Baseline and 6 months.
Change in IMPA
Time frame: Baseline and 6 months.
Change in Interincisal Angle
Time frame: Baseline and 6 months
Change in Upper Lip to S Line Distance
Time frame: Baseline and 6 months
Change in Lower Lip to S Line Distance
Time frame: Baseline and 6 months

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 1 Oct 2026.
Background: PubMed 34329389Al-Zoubi EM, Al-Nimri KS. A comparative study between the effect of reverse curve of Spee archwires and anterior bite turbos in the treatment of deep overbite cases. Angle Orthod. 2022 Jan 1;92(1):36-44. doi: 10.2319/020921-117.1.
Background: PubMed 35730261Wasinwasukul P, Nalamliang N, Pairatchawan N, Thongudomporn U. Effects of anterior bite planes fabricated from acrylic resin and thermoplastic material on masticatory muscle responses and maximum bite force in children with a deep bite: A 6-month randomised controlled trial. J Oral Rehabil. 2022 Oct;49(10):980-992. doi: 10.1111/joor.13351. Epub 2022 Jul 3.
Individual participant dataSharing planned: No. There is currently no plan to share individual participant data with other researchers.

Related trials for Deep Bite Malocclusion

Recruiting
Maxillary Arch Distalization With Infrazygomatic Crest Miniscrews for Class II Malocclusion
Class II Malocclusion
Recruiting
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Malocclusion, Class II Malocclusion
Enrolling by invitationObservational study
Long-term Stability of Treatment With the Twin Block Appliance
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Active, not recruitingObservational study
Comparative Evaluation of Functional and Aesthetic Outcomes of Box and Mini-Wing Genioplasty Techniques
Class II Malocclusion, Dentofacial Deformities
Active, not recruiting
Modified Versus Clear Twin Block for Skeletal Class II Malocclusion
Skeletal Class II Malocclusion

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Ayşe T Altuğ Demiralp, DDS, PhD, Professor principal investigator

Ankara University Faculty of Dentistry Department of Orthodontics

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Anterior Bite Turbo and Fixed Orthodontic Treatment in people with Deep Bite Malocclusion, run by Ankara University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 1 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in Mean Bilateral Masseter Muscle Activity at Rest (time frame: Baseline (before bite turbo placement), 1 month, and 6 months). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07851948, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Oct 2026.