Mental Health and Psychological Well-BeingAI ChatbotNCT07848022
Effectiveness of a Nurse-facilitated Artificial Intelligence Chatbot on Psychological Well-being and Mental Health Stigma Among Patients With Psychiatric Disorders: A Quasi-experimental Study
A study testing Nurse-Facilitated Artificial Intelligence Chatbot in people with Mental Health and Psychological Well-Being, run by Al-Zaytoonah University of Jordan at 1 site in Jordan.
Trial summary
This quasi-experimental study aims to evaluate the effectiveness of a nurse-facilitated artificial intelligence (AI) chatbot in improving psychological well-being and reducing mental health stigma among patients with psychiatric disorders. Read more about this study
- Who is it for?
- Ages 18 to 65 months
- Conditions the study is for
- Mental Health and Psychological Well-Being
- What is being tested?
- Nurse-Facilitated Artificial Intelligence Chatbot
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 72 participants
- Where
- 1 siteJordan
- Study dates
- 11 Jan 2023to 12 May 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 months
- All sexes
- No healthy volunteers
- Child
Inclusion Criteria Adult patients aged 18-65 years. Diagnosed with a psychiatric disorder by a qualified psychiatrist. Receiving care at the selected psychiatric outpatient clinic or mental health facility.
Able to read and communicate in Arabic. Possess a smartphone or device with internet access to use the AI chatbot. Willing to participate and provide informed consent.
Exclusion Criteria Patients experiencing an acute psychiatric episode requiring immediate hospitalization.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of a Nurse-Facilitated Artificial Intelligence Chatbot Intervention on Psychological Well-Being and Mental Health Stigma Among Patients With Psychiatric Disorders: A Quasi-Experimental Study
This quasi-experimental study aims to evaluate the effectiveness of a nurse-facilitated artificial intelligence (AI) chatbot in improving psychological well-being and reducing mental health stigma among patients with psychiatric disorders. Participants will receive support through an AI chatbot supervised by trained psychiatric nurses. The chatbot will provide mental health education, emotional support, coping strategies, and guidance for self-management. Outcomes will include changes in psychological well-being and levels of mental health stigma before and after the intervention. The findings may help determine whether AI-assisted nursing interventions can enhance mental health care and support recovery among individuals with psychiatric disorders.
- Being tested
- Nurse-Facilitated Artificial Intelligence Chatbot
- Keywords
- Artificial Intelligence Chatbot AI Mental Health Intervention Nurse-Facilitated Intervention Psychological Well-Being Mental Health Stigma
- Medical subject headings
- Psychological Well-Being
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nurse-Facilitated Artificial Intelligence ChatbotBehavioural
A nurse-facilitated artificial intelligence chatbot designed to provide psychoeducational information, emotional support, coping strategies, and mental health guidance for patients with psychiatric disorders. The chatbot is supervised by psychiatric nurses and aims to improve psychological well-being and reduce mental health stigma.
| Study group | Role | What they receive |
|---|---|---|
| Usual Care Control Group | No intervention | Participants receive the standard psychiatric care routinely provided by the healthcare facility, including regular psychiatric consultations, prescribed treatment, and follow-up services. Participants in this arm do not receive access to the nurse-facilitated artificial intelligence chatbot during the study period. Outcome measures are assessed at the same time points as the intervention group for comparison purposes. |
| Nurse-Facilitated AI Chatbot Intervention | Experimental | Participants receive the standard psychiatric care routinely provided by the healthcare facility, including regular psychiatric consultations, prescribed treatment, and follow-up services. Participants in this arm do not receive access to the nurse-facilitated artificial intelligence chatbot during the study period. Outcome measures are assessed at the same time points as the intervention group for comparison purposes. Receives: Behavioral: Nurse-Facilitated Artificial Intelligence Chatbot |
What is being measured
The primary outcome is the main question the study is designed to answer.
Psychological Well-being
Change in psychological well-being scores among patients with psychiatric disorders following participation in the nurse-facilitated artificial intelligence chatbot intervention.
Measured: Baseline (pre-intervention) and 2 weeks post-intervention Baseline (pre-intervention) and 4 weeks post-intervention Baseline (pre-intervention) and 3 months post-intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Sep 2026
- Study start11 Jan 2023
- Primary completion11 Apr 2023
- Study completion12 May 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Mental Health and Psychological Well-BeingStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- This is a quasi-experimental, nonrandomized study evaluating the effect of a nurse-facilitated AI chatbot intervention on psychological well-being and mental health stigma among patients with psychiatric disorders.
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 72 participants (actual)
Sponsor and investigators
- Lead sponsor
- Al-Zaytoonah University of Jordan
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Eman Abdelfatah Shokr, Al-Zaytoonah University of Jordan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07848022
- Sponsor's protocol ID
- AlZaytoonahU
- Acronym
- AI Chatbot
- Status last verified
- Sep 2026
- First submitted
- 31 Jul 2026
- Last updated
- 29 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
16. Ryff C. D. (2014). Psychological well-being revisited: advances in the science and practice of eudaimonia. Psychotherapy and psychosomatics, 83(1), 10-28. https://doi.org/10.1159/000353263. 17. Yasuhara, K., Formon, D. L., Phillips, S. & Yenne, E. M. Mental health stigma scale [Database record]. APA PsycTests (2019). https://doi.org/10.1037/t76798-000 18. Andersen, S. M., Randers, A., Jensen, C. M., Bisgaard, C., & Steinhausen, H. C. (2013). Preceding diagnoses to young adult bipolar disorder and schizophrenia in a nationwide study. BMC psychiatry, 13, 343. https://doi.org/10.1186/1471-244X-13-343 19. McKenzie, S. K., Oliffe, J. L., Black, A., & Collings, S. (2022). Men's Experiences of Mental Illness Stigma Across the Lifespan: A Scoping Review. American journal of men's health, 16(1), 15579883221074789. https://doi.org/10.1177/15579883221074789 20. Kirkbride, J. B., Anglin, D. M., Colman, I., Dykxhoorn, J., Jones, P. B., Patalay, P., Pitman, A., Soneson, E., Steare, T., Wright, T., & Griffiths, S. L. (2024). The social determinants of mental health and disorder: evidence, prevention and recommendations. World psychiatry: official journal of the World Psychiatric Association (WPA), 23(1), 58-90. https://doi.org/10.1002/wps.21160 21. Waqas, A., Malik, S., Fida, A., Abbas, N., Mian, N., Miryala, S., Amray, A. N., Shah, Z., & Naveed, S. (2020). Interventions to Reduce Stigma Related to Mental Illnesses in Educational Institutes: a Systematic Review. The Psychiatric quarterly, 91(3), 887-903. https://doi.org/10.1007/s11126-020-09751-4
Study at a glance
From the registry record, last updated by the sponsor on 29 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of a Nurse-Facilitated Artificial Intelligence Chatbot Intervention on Psychological Well-Being and Mental Health Stigma Among Patients With Psychiatric Disorders: A Quasi-Experimental Study
- ClinicalTrials.gov ID
- NCT07848022
- Acronym / sponsor ID
- AI Chatbot / AlZaytoonahU
- Keywords
- Artificial Intelligence Chatbot AI Mental Health Intervention Nurse-Facilitated Intervention Psychological Well-Being Mental Health Stigma
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 72 participants (actual)
- Lead sponsor
- Al-Zaytoonah University of JordanUniversity, hospital or other
- Study start
- 11 Jan 2023 (actual)
- Primary completion
- 11 Apr 2023 (actual)
- Study completion
- 12 May 2024 (actual)
- First posted
- 29 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This quasi-experimental study aims to evaluate the effectiveness of a nurse-facilitated artificial intelligence (AI) chatbot in improving psychological well-being and reducing mental health stigma among patients with psychiatric disorders. Participants will receive support through an AI chatbot supervised by trained psychiatric nurses. The chatbot will provide mental health education, emotional support, coping strategies, and guidance for self-management. Outcomes will include changes in psychological well-being and levels of mental health stigma before and after the intervention. The findings may help determine whether AI-assisted nursing interventions can enhance mental health care and support recovery among individuals with psychiatric disorders.
Study design
- Primary purpose
- Prevention
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- This is a quasi-experimental, nonrandomized study evaluating the effect of a nurse-facilitated AI chatbot intervention on psychological well-being and mental health stigma among patients with psychiatric disorders.
| Arm | Type | Receives |
|---|---|---|
| Usual Care Control Group | No intervention | –Participants receive the standard psychiatric care routinely provided by the healthcare facility, including regular psychiatric consultations, prescribed treatment, and follow-up services. Participants in this arm do not receive access to the nurse-facilitated artificial intelligence chatbot during the study period. Outcome measures are assessed at the same time points as the intervention group for comparison purposes. |
| Nurse-Facilitated AI Chatbot Intervention | Experimental | Behavioral: Nurse-Facilitated Artificial Intelligence ChatbotParticipants receive the standard psychiatric care routinely provided by the healthcare facility, including regular psychiatric consultations, prescribed treatment, and follow-up services. Participants in this arm do not receive access to the nurse-facilitated artificial intelligence chatbot during the study period. Outcome measures are assessed at the same time points as the intervention group for comparison purposes. |
Who may qualify
- Ages
- 18 to 65 months
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nurse-Facilitated Artificial Intelligence ChatbotA nurse-facilitated artificial intelligence chatbot designed to provide psychoeducational information, emotional support, coping strategies, and mental health guidance for patients with psychiatric disorders. The chatbot is supervised by psychiatric nurses and aims to improve psychological well-being and reduce mental health stigma. | Behavioural | Nurse-Facilitated AI Chatbot Intervention |
Primary outcome
Psychological Well-being
Time frame: Baseline (pre-intervention) and 2 weeks post-intervention Baseline (pre-intervention) and 4 weeks post-intervention Baseline (pre-intervention) and 3 months post-intervention
Change in psychological well-being scores among patients with psychiatric disorders following participation in the nurse-facilitated artificial intelligence chatbot intervention.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Sep 2026.
- Results publication16. Ryff C. D. (2014). Psychological well-being revisited: advances in the science and practice of eudaimonia. Psychotherapy and psychosomatics, 83(1), 10-28. https://doi.org/10.1159/000353263. 17. Yasuhara, K., Formon, D. L., Phillips, S. & Yenne, E. M. Mental health stigma scale [Database record]. APA PsycTests (2019). https://doi.org/10.1037/t76798-000 18. Andersen, S. M., Randers, A., Jensen, C. M., Bisgaard, C., & Steinhausen, H. C. (2013). Preceding diagnoses to young adult bipolar disorder and schizophrenia in a nationwide study. BMC psychiatry, 13, 343. https://doi.org/10.1186/1471-244X-13-343 19. McKenzie, S. K., Oliffe, J. L., Black, A., & Collings, S. (2022). Men's Experiences of Mental Illness Stigma Across the Lifespan: A Scoping Review. American journal of men's health, 16(1), 15579883221074789. https://doi.org/10.1177/15579883221074789 20. Kirkbride, J. B., Anglin, D. M., Colman, I., Dykxhoorn, J., Jones, P. B., Patalay, P., Pitman, A., Soneson, E., Steare, T., Wright, T., & Griffiths, S. L. (2024). The social determinants of mental health and disorder: evidence, prevention and recommendations. World psychiatry: official journal of the World Psychiatric Association (WPA), 23(1), 58-90. https://doi.org/10.1002/wps.21160 21. Waqas, A., Malik, S., Fida, A., Abbas, N., Mian, N., Miryala, S., Amray, A. N., Shah, Z., & Naveed, S. (2020). Interventions to Reduce Stigma Related to Mental Illnesses in Educational Institutes: a Systematic Review. The Psychiatric quarterly, 91(3), 887-903. https://doi.org/10.1007/s11126-020-09751-4
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nurse-Facilitated Artificial Intelligence Chatbot in people with Mental Health and Psychological Well-Being, run by Al-Zaytoonah University of Jordan at 1 site in Jordan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 29 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Jordan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Psychological Well-being (time frame: Baseline (pre-intervention) and 2 weeks post-intervention Baseline (pre-intervention) and 4 weeks post-intervention Baseline (pre-intervention) and 3 months post-intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07848022, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Sep 2026.