Chronic Nasal ObstructionNCT07832916

Comparison Between Turbinoplasty Techniques in Chronic Nasal Obstruction Microdebrider Coblation andSubmucosalBipolarDiathermyTechniquesduetohypertrophoidturbinate

A study testing Submucosal Bipolar Diathermy Assisted Turbinoplasty, Coblation-Assisted Turbinoplasty and Microdebrider-Assisted Turbinoplasty in people with Chronic Nasal Obstruction, run by Assiut University.

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Official record

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Trial summary

Who is it for?: Ages 18 to 60 years
Conditions the study is for: Chronic Nasal Obstruction
What is being tested?: Submucosal Bipolar Diathermy Assisted Turbinoplasty, Coblation-Assisted Turbinoplasty and Microdebrider-Assisted Turbinoplasty
Type of treatment: Surgery or procedure
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 66 participants
Where: No sites listed yet
Study dates: Oct 2026to Oct 2028
Phase: Interventional
Are there results?: Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 60 years
All sexes
No healthy volunteers
Adult

Who may be able to join

Adult patients aged 18- 60 years of either sex.
Chronic nasal obstruction of more than 3 months' duration attributable to bilateral inferior turbinate hypertrophy (Grade II or III on endoscopic grading).

Who cannot join

Nasal obstruction primarily attributable to severe septal deviation requiring septoplasty as the main corrective procedure.
Chronic rhinosinusitis with nasal polyposis.
Nasal or paranasal sinus tumors/masses.
Previous nasal, turbinate, or sinus surgery.
Atrophic rhinitis or empty nose syndrome.
Uncontrolled bleeding disorders or use of anticoagulant/antiplatelet therapy that cannot be safely withheld.

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Uncontrolled systemic disease (e.g., uncontrolled diabetes mellitus, hypertension) precluding surgery/anesthesia.
Pregnancy.
Active nasal infection at the time of surgery.
Patient refusal to participate or to complete follow-up.

About this study

Chronic nasal obstruction is one of the most common complaints in otorhinolaryngology practice, with inferior turbinate hypertrophy being a major anatomical cause that significantly impairs nasal airflow and quality of life.(1) It is commonly associated with allergic rhinitis, vasomotor rhinitis, chronic rhinosinusitis, and compensatory hypertrophy secondary to septal deviation. (2) When medical treatment fails, surgical reduction of the inferior turbinate becomes necessary.(2) Available techniques include Microdebrider (3) , Coblation(4), and Submucosal Bipolar Diathermy(5) aim to reduce turbinate volume while maintaining normal mucosal function and are associated with less tissue damage than conventional procedures. (6) Although several surgical techniques have shown good clinical outcomes, no single method has been established as the gold standard. Comparative evidence evaluating microdebrider, coblation, and bipolar in the same prospective study remains limited,(7) particularly in the Egyptian population.

Therefore, this study aims to compare these techniques regarding efficacy, safety, postoperative outcomes, and patient satisfaction to provide evidence that supports appropriate surgical decision-making

Conditions: Chronic Nasal Obstruction
Being tested: Submucosal Bipolar Diathermy Assisted Turbinoplasty, Coblation-Assisted Turbinoplasty, Microdebrider-Assisted Turbinoplasty

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Submucosal Bipolar Diathermy Assisted TurbinoplastyProcedure or surgery
minimally invasive surgical procedure used to shrink enlarged inferior nasal turbinates and improve nasal breathing
Coblation-Assisted TurbinoplastyProcedure or surgery
a minimally invasive surgical procedure that uses low-temperature radiofrequency plasma energy to shrink enlarged nasal turbinates and improve breathing
Microdebrider-Assisted TurbinoplastyProcedure or surgery
a minimally invasive surgical procedure used to reduce the size of enlarged inferior turbinates

Study groups in NCT07832916
Study group	Role	What they receive
Group A	Active comparator	Microdebrider-Assisted Turbinoplasty Receives: Procedure: Microdebrider-Assisted Turbinoplasty
Group B	Active comparator	Coblation-Assisted Turbinoplasty Receives: Procedure: Coblation-Assisted Turbinoplasty
Group c	Active comparator	Submucosal Bipolar Diathermy Assisted Turbinoplasty Receives: Procedure: Submucosal Bipolar Diathermy Assisted Turbinoplasty

What is being measured

The primary outcome is the main question the study is designed to answer.

Change in endoscopic inferior turbinate grade
Measured: 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

Oct 2026Oct 2028

First posted22 Sep 2026
Study startOct 2026 (estimated)
Primary completionOct 2027 (estimated)
Study completionOct 2028 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for Chronic Nasal ObstructionStudies of the same condition, open and under way.
More trials run by Assiut UniversityThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind
Who is masked: Outcomes assessor
Enrolment: 66 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07832916
Sponsor's protocol ID: turbinoplasty
Status last verified: Sep 2026
First submitted: 16 Sep 2026
Last updated: 22 Sep 2026
Results posted: No
Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No

Interested in taking part?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

Official record

Recruiting
Pharyngeal Mucosal Conditioning to Prevent Postoperative Sore Throat in Septoplasty Patients With Severe Nasal Obstruction
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Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.
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Traditional vs. Posterior Nasal Radiofrequency Ablation for Chronic Rhinitis
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All Chronic Nasal Obstruction trials

Study at a glance

From the registry record, last updated by the sponsor on 22 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Comparison Between Turbinoplasty Techniques in Chronic Nasal Obstruction Microdebrider Coblation andSubmucosalBipolarDiathermyTechniquesduetohypertrophoidturbinate
ClinicalTrials.gov ID: NCT07832916
Acronym / sponsor ID: turbinoplasty
Conditions: Chronic Nasal Obstruction
Study type: Interventional
Recruitment status: Not yet recruiting
Enrolment: 66 participants (estimated)
Lead sponsor: Assiut UniversityUniversity, hospital or other
Study start: Oct 2026 (estimated)
Primary completion: Oct 2027 (estimated)
Study completion: Oct 2028 (estimated)
First posted: 22 Sep 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind (outcomes assessor)
Number of arms: 3

Arm	Type	Receives
Group A	Active comparator	Procedure: Microdebrider-Assisted TurbinoplastyMicrodebrider-Assisted Turbinoplasty
Group B	Active comparator	Procedure: Coblation-Assisted TurbinoplastyCoblation-Assisted Turbinoplasty
Group c	Active comparator	Procedure: Submucosal Bipolar Diathermy Assisted TurbinoplastySubmucosal Bipolar Diathermy Assisted Turbinoplasty

Who may qualify

Ages: 18 to 60 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult

Key inclusion criteria (2 listed)

Adult patients aged 18- 60 years of either sex.
Chronic nasal obstruction of more than 3 months' duration attributable to bilateral inferior turbinate hypertrophy (Grade II or III on endoscopic grading).

Key exclusion criteria (10 listed)

Nasal obstruction primarily attributable to severe septal deviation requiring septoplasty as the main corrective procedure.
Chronic rhinosinusitis with nasal polyposis.
Nasal or paranasal sinus tumors/masses.
Previous nasal, turbinate, or sinus surgery.
Atrophic rhinitis or empty nose syndrome.

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Submucosal Bipolar Diathermy Assisted Turbinoplastyminimally invasive surgical procedure used to shrink enlarged inferior nasal turbinates and improve nasal breathing	Procedure or surgery	Group c
Coblation-Assisted Turbinoplastya minimally invasive surgical procedure that uses low-temperature radiofrequency plasma energy to shrink enlarged nasal turbinates and improve breathing	Procedure or surgery	Group B
Microdebrider-Assisted Turbinoplastya minimally invasive surgical procedure used to reduce the size of enlarged inferior turbinates	Procedure or surgery	Group A

Primary outcome

Change in endoscopic inferior turbinate grade
Time frame: 6 months

Results and safety

This study is still under way. Results are not available in the source record yet.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2026.

Related trials for Chronic Nasal Obstruction

Recruiting
Pharyngeal Mucosal Conditioning to Prevent Postoperative Sore Throat in Septoplasty Patients With Severe Nasal Obstruction
Postoperative Sore Throat, Nasal Obstruction
Not yet recruiting
Position-Directed Budesonide Nasal Drops for CRS-associated Olfactory Dysfunction
Chronic Rhinosinusitis (CRS), Olfactory Dysfunction
Not yet recruiting
Active vs. Passive VR During Office-based ENT Procedures
Pain, Anxiety
RecruitingObservational study
Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.
Chronic Rhinosinusitis Phenotype With Nasal Polyps (CRSwNP), Smell Loss
Active, not recruiting
Traditional vs. Posterior Nasal Radiofrequency Ablation for Chronic Rhinitis
Nasal Obstruction, Chronic Rhinitis

Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.

The record lists no contact. Use the official record to reach the sponsor.

Questions about this trial

What is this clinical trial studying?

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 22 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Change in endoscopic inferior turbinate grade (time frame: 6 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07832916.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2026.