This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real WorldIMPLEMENTNCT07832396

Community Study to Increase Mammogram Screening Among Overdue Women

A study testing Evidence-based behavioural intervention in people with This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real World, run by National University Hospital, Singapore at 1 site in Singapore.

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts

Official record

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Trial summary

Breast cancer is the most common cancer among women in Singapore, and regular mammogram screening can detect breast cancer early when treatment is more effective. However, many eligible women do not attend regular mammogram screening despite national screening programs and free screening for eligible women enrolled in… Read more about this study

Who is it for?: Ages 50 to 69 years, women onlyHealthy volunteers can take part
Conditions the study is for: This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real World
What is being tested?: Evidence-based behavioural intervention
Type of treatment: Lifestyle or therapy programme
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 15,000 participants
Where: 1 siteSingapore
Study dates: 1 Nov 2026to 31 Dec 2029
Phase: Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 50 to 69 years
Women only
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

Singaporean citizen
Age 50-69 years
Registered patients of NUHS
No history of breast cancer
Eligible for free mammograms (Signed up with Healthier SG with a primary care provider within the NUHS Primary Care Network)
In each individual trial in this proposed series of trials, the participants will either be:
Repeat screeners: Have undergone a mammogram at least once in the past, but not within the past 2 years Never screeners: Have never done mammogram in the past (no records in EPIC) Active screeners: Have undergone a mammogram within the past 20-24 months but have not scheduled their next screening in Health Appointment System (HAS)

Who cannot join

Diagnosis of breast cancer in EPIC
Pregnant woman

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Singapore1 site

National University Hospital Singapore
Singapore

Other trials in Singapore

About this study

Official title: A Community-Based Implementation Study of Pragmatic Interventions to Improve Mammography Uptake in Non-Screen Adherent Women

The IMPLEMENT Study is a community-based implementation study that will evaluate whether practical, low-cost behavioural interventions can increase mammogram screening among women who are overdue for screening or have never been screened. The interventions have previously been shown to be effective in randomized controlled trials conducted by the study team.

The study will be conducted in the Health District @ Queenstown (HD@QT). Women living in Happy Village @ Mei Ling will receive one behavioural intervention that has been shown to be effective in a previous randomized trial, while eligible women living in the remainder of HD@QT will receive usual care with no study intervention. Different implementation trials will be conducted for different screening populations, including women who have never undergone mammography, women who are overdue for repeat mammography, and women who are due for their next mammogram.

The primary objective is to determine whether implementing these evidence-based interventions in a real-world community setting increases the proportion of women completing mammography within four months. Results from this study will help determine whether these interventions can be integrated into community health programs to improve breast cancer screening participation in Singapore.

Conditions: This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real World
Being tested: Evidence-based behavioural intervention
Keywords: Breast Neoplasms, Mammography
Medical subject headings: Breast Neoplasms

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Evidence-based behavioural interventionBehavioural
Evidence-based behavioural intervention delivered to eligible women in Happy Village @ Mei Ling to encourage mammography screening. The specific intervention, delivery method, frequency, and duration will be defined for each screening population based on the corresponding previous randomized trial. In Trial 1 the intervention will be mailed reminder (MR) with dedicated appointment scheduling hotline. In Trial 2, the intervention will be MR with prescheduled appointment.

Study groups in NCT07832396
Study group	Role	What they receive
Evidence-based behavioural intervention	Experimental	Eligible women residing in Happy Village @ Mei Ling will receive the evidence-based behavioural intervention specified for their screening population. The intervention will be implemented in the community to increase mammography completion within four months. In Trial A on defaulted repeats screeners the intervention will be Mailed Reminder (MR) with dedicated hotline scheduling. In Trial 2 on never-screeners the intervention will be MR with Prescheduled Appointment. Receives: Behavioral: Evidence-based behavioural intervention
Comparator group	No intervention	Eligible women residing in the remainder of HD@QT will receive usual care without the study-delivered behavioural intervention. Mammography completion will be assessed using the same outcome definition and follow-up period.

What is being measured

The primary outcome is the main question the study is designed to answer.

Proportion of eligible women who complete mammography within four months of intervention delivery.
This community-based implementation study will evaluate the effectiveness of evidence-based behavioural interventions to increase mammography screening in eligible women residing in the Health District @ Queenstown. Eligible women living in Happy Village @ Mei Ling will receive the intervention assigned to their screening population, while eligible women living in the remainder of the health district will receive usual care. The study will include implementation cohorts of women who have never undergone mammography, women who are overdue for repeat mammography, and women who are due for their next mammogram. The intervention will be delivered in parallel to usual care, and allocation will be non-randomized based on residential location. Mammography completion will be assessed within four months of intervention delivery.
Measured: 4 month

Secondary outcomes (2)

Time from mailed reminder to mammography completion
Time from intervention mailer delivery to completion of mammography, measured in days.
Measured: From mailer delivery through 4 months.
Time to appointment booking
Time from intervention mailer delivery to the first mammography appointment booking, measured in days.
Measured: From mailer delivery through 4 months.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Nov 202631 Dec 2029

First posted22 Sep 2026
Study start1 Nov 2026 (estimated)
Primary completion1 Nov 2028 (estimated)
Study completion31 Dec 2029 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Other trials for This Study Evaluates Interventions to Increase Surveillance Mammography Uptake for Early Breast Cancer Detection Among Singaporean Women in Real WorldStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Health services research
Allocation: Non-randomised
Intervention model: Parallel groups
Model description: Each woman belongs to one group and receives either the intervention or usual care during the study.
Masking: None (open label)
Enrolment: 15,000 participants (estimated)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07832396
Sponsor's protocol ID: 2026-0741
Acronym: IMPLEMENT
Status last verified: Aug 2026
First submitted: 16 Sep 2026
Last updated: 22 Sep 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No