Surgical AnesthesiaNCT07814703
Intercostobrachial Nerve Block vs Erector Spinae Block for Medial Arm A-V Fistula Surgery
A study testing intercostobrachial nerve block and ultrasound-guided erector spinae plane block in people with Surgical Anesthesia, run by Fayoum University Hospital at 1 site in Egypt.
Trial summary
Comparison Between Ultrasound-guided Intercostobrachial Nerve Block with Supraclavicular Block versus Ultrasound -guided Erector Spinae block with Supraclavicular Block for Medial Arm A-V Fistula Surgery Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Surgical Anesthesia
- What is being tested?
- intercostobrachial nerve block and ultrasound-guided erector spinae plane block
- Type of treatment
- Injection or infusion, Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 158 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Apr 2026to 1 Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- ESRD patient undergoing creation AVF in the medial side of the arm.
Who cannot join
- 1. Patient refusal 2. Drug allergies 3. Body Mass Index of 35 kg/m² or more 4. Coagulation abnormalities 5. Severe heart, kidney, and liver diseases, 6. Pregnancy 7. Vasculitis 8. Unstable hemodynamics 9. Upper extremity neuropathy 10. Mental illness 11. Seizures 12. Contralateral chest problems 13. Infection at site of injection
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Fayoum University hospital
Al Fayyum, Madīnat Al Fayyūm, Faiyum Governorate, 4312
taghreed shabaan korany, Msc, 00201007195396, Taghreedshaban60@gmail.com
About this study
Official title: Comparison Between Ultrasound-guided Intercostobrachial Nerve Block With Supraclavicular Block Versus Ultrasound -Guided Erector Spinae Block With Supraclavicular Block for Medial Arm A-V Fistula Surgery: Observer Blinded Randomized Comparative Study
Comparison Between Ultrasound-guided Intercostobrachial Nerve Block with Supraclavicular Block versus Ultrasound -guided Erector Spinae block with Supraclavicular Block for Medial Arm A-V Fistula Surgery
Read the detailed description
Intravenous access will be obtained with an 18-gauge intravenous (IV) cannula in the contralateral upper limb of the surgical site and monitors (pulse oximeter, electrocardiography, non-invasive blood pressure and capnography) will be applied.
All patients will receive 5 L/min of oxygen was delivered via a face mask.
In all patients, the SCPB was performed before the assigned supplemental block. Patients were placed supine with the head turned approximately 30° away from the surgical side and a small towel positioned between the scapulae to optimize access. After aseptic preparation, a high-frequency linear US probe (6 - 12 MHz) of ultrasound US machine (LOGIQ P7) covered with a sterile sheath was placed in the coronal-oblique plane just superior to the clavicle and lateral to the sternocleidomastoid muscle to visualize the subclavian artery medially, the brachial plexus divisions as a cluster of hypoechoic round structures lateral to the artery, and the first rib and pleura as hyperechoic lines deep to the artery.
Lidocaine 1% was injected at the entry site of the needle, Using an in-plane lateral-to-medial approach, a 22-G, 80-mm insulated block needle was advanced under continuous US guidance toward the "corner pocket" bordered by the subclavian artery medially, the first rib inferiorly, and the brachial plexus laterally. After negative aspiration, 5 - 10 mL of was injected into the corner pocket, and the needle was redirected to deposit additional 3 - 5 mL aliquots around the remaining plexus divisions to ensure circumferential spread, for a total of a mixture of 15 ml each of 0.5% bupivacaine and 2% lidocaine.
In group (I), following the SCPB, the intercostobrachial nerve (ICBN) was blocked using Ultrasound-Guided Intercostobrachial Nerve Block Procedure after SCPB, the ICBN was blocked under US guidance at the mid-axillary level. The patient was positioned supine with the arm abducted to 90°. A high-frequency linear probe (6 - 12 MHz) was placed transversely over the mid-axillary line at the level of the 2nd-3rd intercostal spaces. The axillary vein and artery were first visualized, then the probe was adjusted superficially to identify the fascial plane between the subcutaneous tissue and the serratus anterior muscle.
The ICBN appeared as a small hyperechoic oval or linear structure within this plane. Using an in-plane, posterio-anterior needle approach, an 80-mm block needle was advanced into the fascial plane. After confirming negative aspiration, 10 ml of the same local anesthetic mixture was administered (0.5% bupivacaine and 2% lidocaine), and real-time sonographic imaging confirmed the spread of local anesthetic along the plane both anteriorly and posteriorly.
In group (E) for the ultrasound-guided erector spinae plane block. At first the patient will be placed in a lateral decubitus with the operation site up and we will count the vertebrae from cephalad to caudal direction until we reach T2 spinous process as the first palpable spinous process is C7. Ultrasound probe will be placed vertically 3 cm lateral to the T2 spinous process. linear transducer was placed on the superior-posterior aspect of the operation site shoulder close to the neck to observe the short axis view of the transverse processes of T2 and T3. The same type of block needle was inserted and advanced in a caudad-to-cephalad direction toward the space between the two transverse processes using in-plane ultrasound guidance. Immediately after penetrating the anterior fascia of the erector spinae muscles, 10 ml of the same local anesthetic mixture was administered.
Twenty minutes after the completion of the nerve blocks, a pinprick test showed that the entire upper arm and lateral aspect of the left upper chest wall were anesthetized. Thereafter, surgery was initiated.
- Conditions
- Surgical Anesthesia
- Being tested
- intercostobrachial nerve block, ultrasound-guided erector spinae plane block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
intercostobrachial nerve blockProcedure or surgery
the intercostobrachial nerve will be blocked using Ultrasound-Guided Procedure after SCPB, the ICBN was blocked under US guidance at the mid-axillary level. The patient was positioned supine with the arm abducted to 90°. A high-frequency linear probe will be placed transversely over the mid-axillary line at the level of the 2nd-3rd intercostal spaces. The axillary vein and artery were first visualized, then the probe was adjusted superficially to identify the fascial plane between the subcutaneous tissue and the serratus anterior muscle. The ICBN appeared as a small hyperechoic oval or linear structure within this plane. Using an in-plane, posterio-anterior needle approach, an 80-mm block needle was advanced into the fascial plane. After confirming negative aspiration, 10 ml of the same local anesthetic mixture was administered (0.5% bupivacaine and 2% lidocaine)
ultrasound-guided erector spinae plane blockProcedure or surgery
patient will be placed in a lateral decubitus with the operation site up and we will count the vertebrae from cephalad to caudal direction until we reach T2 spinous process as the first palpable spinous process is C7. Ultrasound probe will be placed vertically 3 cm lateral to the T2 spinous process. linear transducer was placed on the superior-posterior aspect of the operation site shoulder close to the neck to observe the short axis view of the transverse processes of T2 and T3. The same type of block needle was inserted and advanced in a caudad-to-cephalad direction toward the space between the two transverse processes using in-plane ultrasound guidance. Immediately after penetrating the anterior fascia of the erector spinae muscles, 10 ml of the same local anesthetic mixture was administered
| Study group | Role | What they receive |
|---|---|---|
| intercostobrachial nerve block | Active comparator | Not described Receives: Procedure: intercostobrachial nerve block |
| ultrasound-guided erector spinae plane block | Active comparator | Not described Receives: Procedure: ultrasound-guided erector spinae plane block |
What is being measured
The primary outcome is the main question the study is designed to answer.
achievement of complete sensory block
pinprick test showed that the entire upper arm and lateral aspect of the left upper chest wall are anesthetized
Measured: 20 minutes after the completion of the nerve blocks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Sep 2026
- Study start1 Apr 2026
- Primary completion1 Apr 2027 (estimated)
- Study completion1 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Surgical AnesthesiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Investigator
- Enrolment
- 158 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Fayoum University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Taghreed shaban, Fayoum University Hospital
- Investigators
- mohamed ahmed Ismail, professor, Study chair, Faculty of medicine,Fayoum University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07814703
- Sponsor's protocol ID
- D475
- Status last verified
- Sep 2026
- First submitted
- 6 Sep 2026
- Last updated
- 11 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 11 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Between Ultrasound-guided Intercostobrachial Nerve Block With Supraclavicular Block Versus Ultrasound -Guided Erector Spinae Block With Supraclavicular Block for Medial Arm A-V Fistula Surgery: Observer Blinded Randomized Comparative Study
- ClinicalTrials.gov ID
- NCT07814703
- Acronym / sponsor ID
- D475
- Conditions
- Surgical Anesthesia
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 158 participants (estimated)
- Lead sponsor
- Fayoum University HospitalUniversity, hospital or other
- Study start
- 1 Apr 2026 (actual)
- Primary completion
- 1 Apr 2027 (estimated)
- Study completion
- 1 Jun 2027 (estimated)
- First posted
- 11 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Comparison Between Ultrasound-guided Intercostobrachial Nerve Block with Supraclavicular Block versus Ultrasound -guided Erector Spinae block with Supraclavicular Block for Medial Arm A-V Fistula Surgery
Detailed description
Intravenous access will be obtained with an 18-gauge intravenous (IV) cannula in the contralateral upper limb of the surgical site and monitors (pulse oximeter, electrocardiography, non-invasive blood pressure and capnography) will be applied.
All patients will receive 5 L/min of oxygen was delivered via a face mask.
In all patients, the SCPB was performed before the assigned supplemental block. Patients were placed supine with the head turned approximately 30° away from the surgical side and a small towel positioned between the scapulae to optimize access. After aseptic preparation, a high-frequency linear US probe (6 - 12 MHz) of ultrasound US machine (LOGIQ P7) covered with a sterile sheath was placed in the coronal-oblique plane just superior to the clavicle and lateral to the sternocleidomastoid muscle to visualize the subclavian artery medially, the brachial plexus divisions as a cluster of hypoechoic round structures lateral to the artery, and the first rib and pleura as hyperechoic lines deep to the artery.
Lidocaine 1% was injected at the entry site of the needle, Using an in-plane lateral-to-medial approach, a 22-G, 80-mm insulated block needle was advanced under continuous US guidance toward the "corner pocket" bordered by the subclavian artery medially, the first rib inferiorly, and the brachial plexus laterally. After negative aspiration, 5 - 10 mL of was injected into the corner pocket, and the needle was redirected to deposit additional 3 - 5 mL aliquots around the remaining plexus divisions to ensure circumferential spread, for a total of a mixture of 15 ml each of 0.5% bupivacaine and 2% lidocaine.
In group (I), following the SCPB, the intercostobrachial nerve (ICBN) was blocked using Ultrasound-Guided Intercostobrachial Nerve Block Procedure after SCPB, the ICBN was blocked under US guidance at the mid-axillary level. The patient was positioned supine with the arm abducted to 90°. A high-frequency linear probe (6 - 12 MHz) was placed transversely over the mid-axillary line at the level of the 2nd-3rd intercostal spaces. The axillary vein and artery were first visualized, then the probe was adjusted superficially to identify the fascial plane between the subcutaneous tissue and the serratus anterior muscle.
The ICBN appeared as a small hyperechoic oval or linear structure within this plane. Using an in-plane, posterio-anterior needle approach, an 80-mm block needle was advanced into the fascial plane. After confirming negative aspiration, 10 ml of the same local anesthetic mixture was administered (0.5% bupivacaine and 2% lidocaine), and real-time sonographic imaging confirmed the spread of local anesthetic along the plane both anteriorly and posteriorly.
In group (E) for the ultrasound-guided erector spinae plane block. At first the patient will be placed in a lateral decubitus with the operation site up and we will count the vertebrae from cephalad to caudal direction until we reach T2 spinous process as the first palpable spinous process is C7. Ultrasound probe will be placed vertically 3 cm lateral to the T2 spinous process. linear transducer was placed on the superior-posterior aspect of the operation site shoulder close to the neck to observe the short axis view of the transverse processes of T2 and T3. The same type of block needle was inserted and advanced in a caudad-to-cephalad direction toward the space between the two transverse processes using in-plane ultrasound guidance. Immediately after penetrating the anterior fascia of the erector spinae muscles, 10 ml of the same local anesthetic mixture was administered.
Twenty minutes after the completion of the nerve blocks, a pinprick test showed that the entire upper arm and lateral aspect of the left upper chest wall were anesthetized. Thereafter, surgery was initiated.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| intercostobrachial nerve block | Active comparator | Procedure: intercostobrachial nerve block |
| ultrasound-guided erector spinae plane block | Active comparator | Procedure: ultrasound-guided erector spinae plane block |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- ESRD patient undergoing creation AVF in the medial side of the arm.
Key exclusion criteria (1 listed)
- 1. Patient refusal 2. Drug allergies 3. Body Mass Index of 35 kg/m² or more 4. Coagulation abnormalities 5. Severe heart, kidney, and liver diseases, 6. Pregnancy 7. Vasculitis 8. Unstable hemodynamics 9. Upper extremity neuropathy 10. Mental illness 11. Seizures 12. Contralateral chest problems 13. Infection at site of injection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| intercostobrachial nerve blockthe intercostobrachial nerve will be blocked using Ultrasound-Guided Procedure after SCPB, the ICBN was blocked under US guidance at the mid-axillary level. The patient was positioned supine with the arm abducted to 90°. A high-frequency linear probe will be placed transversely over the mid-axillary line at the level of the 2nd-3rd intercostal spaces. The axillary vein and artery were first visualized, then the probe was adjusted superficially to identify the fascial plane between the subcutaneous tissue and the serratus anterior muscle. The ICBN appeared as a small hyperechoic oval or linear structure within this plane. Using an in-plane, posterio-anterior needle approach, an 80-mm block needle was advanced into the fascial plane. After confirming negative aspiration, 10 ml of the same local anesthetic mixture was administered (0.5% bupivacaine and 2% lidocaine) | Procedure or surgery | intercostobrachial nerve block |
| ultrasound-guided erector spinae plane blockpatient will be placed in a lateral decubitus with the operation site up and we will count the vertebrae from cephalad to caudal direction until we reach T2 spinous process as the first palpable spinous process is C7. Ultrasound probe will be placed vertically 3 cm lateral to the T2 spinous process. linear transducer was placed on the superior-posterior aspect of the operation site shoulder close to the neck to observe the short axis view of the transverse processes of T2 and T3. The same type of block needle was inserted and advanced in a caudad-to-cephalad direction toward the space between the two transverse processes using in-plane ultrasound guidance. Immediately after penetrating the anterior fascia of the erector spinae muscles, 10 ml of the same local anesthetic mixture was administered | Procedure or surgery | ultrasound-guided erector spinae plane block |
Primary outcome
achievement of complete sensory block
Time frame: 20 minutes after the completion of the nerve blocks
pinprick test showed that the entire upper arm and lateral aspect of the left upper chest wall are anesthetized
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Sep 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
mohamed ahmed Ismail, professor study chair
Faculty of medicine,Fayoum University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing intercostobrachial nerve block and ultrasound-guided erector spinae plane block in people with Surgical Anesthesia, run by Fayoum University Hospital at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact taghreed shabaan korany, assistant lecturer (00201007195396, Taghreedshaban60@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
achievement of complete sensory block (time frame: 20 minutes after the completion of the nerve blocks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Sep 2026.