AnemiaNCT07814378
Impact of Iron Supplementation During Pregnancy
An observational study of Anemia and Iron Deficiency Anaemia in Childbirth, run by Johann Wolfgang Goethe University Hospital at 2 sites in Germany.
Trial summary
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth. Around half of pregnant women develop anemia, and after delivery, up to 85% of women may be affected. Read more about this study
- Who is it for?
- Ages 18 years and older, women only
- Conditions the study is for
- Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
- What is being tested?
- Iron
- How many people
- 800 participants
- Where
- 2 sitesGermany
- Study dates
- 1 Oct 2026to 31 Dec 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- No healthy volunteers
- Adult, Older adult
Study population: anemia walk-in clinic
Who may be able to join
- Pregnancy
Who cannot join
- Thalassemia
- Sickle cell disease
- Aplastic anemia
- Hemochromatosis
- Chronic inflammatory diseases associated with anemia of chronic disease
- Severe renal insufficiency
- Intravenous iron administration within 3 months prior to enrollment
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Germany2 sites
University Hospital Frankfurt, Department for Anaesthesiolgy, Intensive Care, and Pain Therapy
Frankfurt
Kai Zacharowski, MD, 049-069-6301-5868, zacharowski@med.uni-frankfurt.de
University Hospital Würzburg, Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine
Würzburg
Peter Kranke, MD, +49 931 201-30001, kranke_p@ukw.de
Patrick Meybohm, MD, +49 931 201-30001
About this study
Official title: Impact of Iron Supplementation on Haemoglobin Levels and Quality-of-life in Iron-deficient (Anaemic) Women Before and After Delivery
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth. Around half of pregnant women develop anemia, and after delivery, up to 85% of women may be affected.
This study looks at whether iron given through a vein (intravenous iron) can improve blood levels and how women feel and function in everyday life before and after giving birth.
- Conditions
- Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
- Being tested
- Iron
- Keywords
- Pregancy, Iron deficiency, Anemia
- Medical subject headings
- Anemia, Iron Deficiencies
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
IronDrug
Iron supplementation will be performed according to Hamza et al., Recommendations of the AGG (Obstetrics Working Group, Section for Maternal Diseases) for the Management of Anemia in Pregnancy - Part 1 (Iron Deficiency Anemia) (https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2628-7308.pdf)
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of patients achieving an increase in hemoglobin concentration of ≥1 g/dL
Proportion of patients with an increase in hemoglobin concentration of ≥1 g/dL from before the first intravenous iron administration to the last available measurement before delivery
Measured: between iron supplementation and follow-up: 2-4 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Sep 2026
- Study start1 Oct 2026 (estimated)
- Primary completion30 Aug 2028 (estimated)
- Study completion31 Dec 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AnemiaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 800 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Johann Wolfgang Goethe University Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Wuerzburg University Hospital
- Responsible party
- Principal investigator, Dr. Patrick Meybohm, M.D., Johann Wolfgang Goethe University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07814378
- Sponsor's protocol ID
- 2026-2980
- Status last verified
- Sep 2026
- First submitted
- 4 Sep 2026
- Last updated
- 11 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Iron Supplementation on Haemoglobin Levels and Quality-of-life in Iron-deficient (Anaemic) Women Before and After Delivery
- ClinicalTrials.gov ID
- NCT07814378
- Acronym / sponsor ID
- 2026-2980
- Conditions
- Anemia, Iron Deficiency Anaemia in Childbirth, Pregnancy
- Keywords
- Pregancy, Iron deficiency, Anemia
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 800 participants (estimated)
- Lead sponsor
- Johann Wolfgang Goethe University HospitalUniversity, hospital or other
- Collaborators
- Wuerzburg University Hospital
- Study start
- 1 Oct 2026 (estimated)
- Primary completion
- 30 Aug 2028 (estimated)
- Study completion
- 31 Dec 2028 (estimated)
- First posted
- 11 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
During pregnancy, iron deficiency is the most common cause of anemia. Anemia is very common during pregnancy and after childbirth. Around half of pregnant women develop anemia, and after delivery, up to 85% of women may be affected.
This study looks at whether iron given through a vein (intravenous iron) can improve blood levels and how women feel and function in everyday life before and after giving birth.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- anemia walk-in clinic
Key inclusion criteria (1 listed)
- Pregnancy
Key exclusion criteria (7 listed)
- Thalassemia
- Sickle cell disease
- Aplastic anemia
- Hemochromatosis
- Chronic inflammatory diseases associated with anemia of chronic disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| IronIron supplementation will be performed according to Hamza et al., Recommendations of the AGG (Obstetrics Working Group, Section for Maternal Diseases) for the Management of Anemia in Pregnancy - Part 1 (Iron Deficiency Anemia) (https://www.thieme-connect.com/products/ejournals/pdf/10.1055/a-2628-7308.pdf) | Drug | – |
Primary outcome
Proportion of patients achieving an increase in hemoglobin concentration of ≥1 g/dL
Time frame: between iron supplementation and follow-up: 2-4 weeks
Proportion of patients with an increase in hemoglobin concentration of ≥1 g/dL from before the first intravenous iron administration to the last available measurement before delivery
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Sep 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Anemia and Iron Deficiency Anaemia in Childbirth, run by Johann Wolfgang Goethe University Hospital at 2 sites in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 11 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Suma Choorapoikayil, PhD (049-069-6301-83169, Choorapoikayil@med.uni-frankfurt.de), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proportion of patients achieving an increase in hemoglobin concentration of ≥1 g/dL (time frame: between iron supplementation and follow-up: 2-4 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Sep 2026.