Carpal Tunnel Syndrome (CTS)ELECTRO-CTSNCT07803939
Electrophysiological and Functional Recovery After Carpal Tunnel Release
A study testing Primary Carpal Tunnel Release Surgery in people with Carpal Tunnel Syndrome (CTS), run by Istanbul Medipol University Hospital.
Trial summary
Carpal tunnel syndrome occurs when the median nerve is compressed at the wrist. It can cause pain, numbness, tingling, reduced hand strength, and difficulty performing daily activities. Read more about this study
- Who is it for?
- Ages 18 to 75 years
- Conditions the study is for
- Carpal Tunnel Syndrome (CTS)
- What is being tested?
- Primary Carpal Tunnel Release Surgery
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- No sites listed yet
- Study dates
- Sep 2026to Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age between 18 and 75 years.
- Clinical and electrophysiological diagnosis of carpal tunnel syndrome.
- Scheduled to undergo primary carpal tunnel release surgery based on routine clinical evaluation.
- Availability of a preoperative nerve conduction study.
- Ability to understand and complete the study assessments and questionnaires.
- Ability to read and understand Turkish.
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- Willingness to participate and provide written informed consent.
- Ability and willingness to attend the planned postoperative follow-up assessments.
- For participants with bilateral carpal tunnel syndrome who undergo unilateral surgery during the study period, only the operated hand will be included in the study. Two hands from the same participant will not be analyzed as independent observations.
Who cannot join
- Previous carpal tunnel release surgery on the study hand.
- Planned revision carpal tunnel surgery.
- Electrophysiological evidence of generalized polyneuropathy.
- Another peripheral neuropathy affecting the median nerve or function of the study hand.
- Active cervical radiculopathy or brachial plexopathy.
- A central or peripheral neurological disorder that substantially affects upper-extremity function.
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- History of major trauma or surgery involving the study hand or wrist that may affect outcome assessments.
- Active inflammatory rheumatologic disease.
- Pregnancy.
- Uncontrolled systemic disease that may interfere with surgery, assessment, or follow-up.
- Cognitive or communication impairment that prevents completion of the study assessments.
- Inability to complete the planned postoperative follow-up assessments.
- Participants with controlled diabetes mellitus will not be excluded solely because of diabetes. However, participants with electrophysiologically confirmed generalized polyneuropathy will be excluded. Diabetes status will be recorded and considered as a potential confounding variable in the analyses.
About this study
Official title: Relationship Between Electrophysiological Recovery of the Median Nerve and Clinical and Functional Outcomes After Carpal Tunnel Release: A Prospective Observational Cohort Study
Carpal tunnel syndrome occurs when the median nerve is compressed at the wrist. It can cause pain, numbness, tingling, reduced hand strength, and difficulty performing daily activities. Carpal tunnel release surgery is commonly performed when symptoms do not improve with conservative treatment or when nerve compression is severe. However, recovery after surgery may differ between patients, and improvement in nerve conduction may not occur at the same rate as improvement in symptoms and hand function.
The purpose of this prospective observational study is to examine the relationship between electrophysiological recovery of the median nerve and clinical and functional recovery after carpal tunnel release surgery. Adults who are already scheduled to undergo primary carpal tunnel release as part of their routine clinical care will be invited to participate. The decision to perform surgery will be made by the treating physician independently of study participation.
Read more
Participants will undergo clinical and functional assessments before surgery and at postoperative week 8 These assessments will include questionnaires about carpal tunnel symptoms and upper-extremity function, pain severity, grip and pinch strength, sensory testing, and clinical examination. Nerve conduction studies will be evaluated before surgery and at postoperative month 3.
The study will assess whether changes in median nerve conduction are associated with changes in symptoms, upper-extremity function, pain, hand strength, and sensory function. The possible effects of age, sex, body mass index, symptom duration, diabetes, and preoperative electrophysiological severity on recovery will also be examined. No experimental drug, device, surgical technique, or additional treatment will be assigned as part of this study.
Read the detailed description
Carpal tunnel syndrome is the most common peripheral nerve entrapment neuropathy of the upper extremity and results from compression of the median nerve within the carpal tunnel. Patients may experience numbness, tingling, nocturnal paresthesia, pain, sensory loss, reduced grip strength, and, in advanced cases, thenar muscle weakness or atrophy. These impairments may negatively affect sleep, occupational performance, daily activities, and overall upper-extremity function.
Carpal tunnel release surgery aims to decompress the median nerve and is generally performed in patients who do not obtain adequate benefit from conservative treatment or who have progressive neurological or electrophysiological abnormalities. Although improvements in pain, paresthesia, and hand function are commonly observed after surgery, the rate and extent of recovery may vary between patients. Clinical improvement may also occur at a different rate from electrophysiological recovery of the median nerve.
This is a single-center, prospective observational cohort study involving adults with clinically and electrophysiologically confirmed carpal tunnel syndrome who are scheduled to undergo primary carpal tunnel release surgery as part of routine clinical care. The decision to perform surgery and the selection of the surgical technique will be made by the treating physician independently of participation in the study. Participation will not influence the surgical decision or the participant's routine treatment. No experimental intervention or additional treatment will be assigned by the investigators.
Only the surgically treated hand will be included in the analysis. For participants with bilateral carpal tunnel syndrome who undergo unilateral surgery during the study period, the operated hand will be evaluated. Two hands from the same participant will not be analyzed as independent observations.
Clinical and functional evaluations will be performed at baseline before surgery and at postoperative week 8. The evaluations will include the Boston Carpal Tunnel Questionnaire, Quick Disabilities of the Arm, Shoulder and Hand questionnaire, Numeric Rating Scale for pain, grip strength, pinch strength, Semmes-Weinstein monofilament testing, static two-point discrimination, and Tinel and Phalen tests.
Standard nerve conduction study findings obtained during routine clinical evaluation will be recorded at baseline and postoperative month 3. Electrophysiological variables will include median nerve distal motor latency, compound muscle action potential amplitude, sensory distal latency, sensory nerve action potential amplitude, and sensory nerve conduction velocity. Electrophysiological severity will be classified using the Bland neurophysiological grading scale. Needle electromyography will not be mandatory for study participation and will only be performed when clinically indicated as part of routine care.
The primary objective is to determine whether electrophysiological changes in the median nerve between baseline and postoperative month 6 are associated with changes in carpal tunnel symptoms and upper-extremity function. Particular emphasis will be placed on changes in distal motor latency and sensory nerve conduction velocity and their relationships with changes in the Boston Carpal Tunnel Questionnaire and QuickDASH scores.
Secondary analyses will examine the relationships between electrophysiological recovery and changes in pain severity, grip strength, pinch strength, monofilament sensation, and two-point discrimination. The study will also investigate whether demographic and clinical factors, including age, sex, body mass index, symptom duration, hand dominance, operated side, occupational hand use, diabetes mellitus, and preoperative electrophysiological severity, are associated with postoperative clinical, functional, or electrophysiological recovery.
The planned enrollment is approximately 70 to 100 participants. Findings from this study may help clarify the extent to which objective nerve conduction recovery reflects patient-reported and performance-based recovery after carpal tunnel release surgery.
- Conditions
- Carpal Tunnel Syndrome (CTS)
- Being tested
- Primary Carpal Tunnel Release Surgery
- Keywords
- Carpal Tunnel Release, Median Nerve, Electrophysiological Recovery, Hand Function, QuickDASH
- Medical subject headings
- Carpal Tunnel Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Primary Carpal Tunnel Release SurgeryProcedure or surgery
Participants will undergo primary carpal tunnel release surgery as part of their routine clinical care. The procedure aims to decompress the median nerve by releasing the transverse carpal ligament. The decision to perform surgery, the timing of surgery, and the surgical technique will be determined by the treating physician independently of study participation. The study will not require an experimental surgical technique or any modification of the participant's standard treatment. Participants will undergo clinical and functional follow-up assessments, and median nerve conduction findings will be evaluated before surgery and at postoperative month 6.
| Study group | Role | What they receive |
|---|---|---|
| Carpal Tunnel Release Group | Other | Participants with clinically and electrophysiologically confirmed carpal tunnel syndrome who are scheduled to undergo primary carpal tunnel release surgery as part of routine clinical care will be included in this single study arm. The decision to perform surgery and the surgical technique will be determined by the treating physician independently of study participation. Clinical and functional assessments will be performed before surgery and at postoperative week 8. Median nerve conduction findings will be evaluated before surgery and at postoperative month 3. No experimental drug, device, surgical technique, or additional treatment will be administered as part of the study. Receives: Procedure: Primary Carpal Tunnel Release Surgery |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Median Nerve Distal Motor Latency
Median nerve distal motor latency will be measured by a standardized nerve conduction study and recorded in milliseconds (ms). Change will be calculated as the postoperative month 6 value minus the preoperative value. A reduction in distal motor latency indicates electrophysiological improvement.
Measured: Baseline and postoperative week 8
Secondary outcomes (8)
Change in Median Nerve Sensory Nerve Conduction Velocity
Median nerve sensory nerve conduction velocity will be measured by a standardized nerve conduction study and recorded in meters per second (m/s). Change will be calculated as the postoperative month 6 value minus the preoperative value. An increase in sensory nerve conduction velocity indicates electrophysiological improvement.
Measured: Baseline and postoperative week 8
The Boston Carpal Tunnel Questionnaire consists of the Symptom Severity Scale and the Functional Status Scale. Each item is scored from 1 to 5, and the mean score is calculated separately for each subscale. Higher scores indicate greater symptom severity
The Boston Carpal Tunnel Questionnaire consists of the Symptom Severity Scale and the Functional Status Scale. Each item is scored from 1 to 5, and the mean score is calculated separately for each subscale. Higher scores indicate greater symptom severity or functional limitation. Change will be calculated relative to the baseline score. A reduction in score indicates clinical and functional improvement.
Measured: Baseline, postoperative week 8
Change in Quick Disabilities of the Arm, Shoulder and Hand Score
Upper-extremity disability will be assessed using the Quick Disabilities of the Arm, Shoulder and Hand questionnaire. The total score ranges from 0 to 100, with higher scores indicating greater disability. Change will be calculated relative to the baseline score. A reduction in score indicates improvement in upper-extremity function.
Measured: Baseline, postoperative week 8
Change in Median Nerve Sensory Nerve Action Potential Amplitude
Description: Median nerve sensory nerve action potential amplitude will be measured by nerve conduction study and recorded in microvolts (µV). Change will be calculated as the postoperative month 3 value minus the baseline value. A higher amplitude generally indicates better sensory nerve function.
Measured: Time Frame: Baseline and postoperative month 3
Change in Median Nerve Compound Muscle Action Potential Amplitude
Description: Median nerve compound muscle action potential amplitude will be measured by nerve conduction study and recorded in millivolts (mV). Change will be calculated as the postoperative month 3 value minus the baseline value. A higher amplitude generally indicates better motor nerve function.
Measured: Time Frame: Baseline and postoperative month 3
Change in Numeric Rating Scale Pain Score
Description: Hand and wrist pain intensity will be evaluated using an 11-point Numeric Rating Scale ranging from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. A reduction in score indicates improvement.
Measured: Baseline, postoperative week 8, month 3,
Change in Semmes-Weinstein Monofilament Sensory Threshold
Description: Touch-pressure sensation will be evaluated using Semmes-Weinstein monofilaments at the thumb, index finger, and middle finger of the operated hand. The lowest monofilament level perceived at each location will be recorded. A lower sensory threshold indicates better touch-pressure sensitivity.
Measured: Baseline, postoperative week 8, month 3,
Change in Static Two-Point Discrimination Distance
Description: Static two-point discrimination will be evaluated at the index and middle fingertips of the operated hand. The shortest distance at which two separate points can be distinguished will be recorded in millimeters (mm). A reduction in distance indicates improved sensory discrimination.
Time Frame: Baseline, postoperative week 6, month 3,
Measured: Time Frame: Baseline, postoperative week 8, month 3,
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Sep 2026
- Study startSep 2026 (estimated)
- Primary completionOct 2026 (estimated)
- Study completionNov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Carpal Tunnel Syndrome (CTS)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- This is a prospective, single-group study of adults undergoing primary carpal tunnel release surgery. All participants will receive carpal tunnel release as part of their routine clinical care and will be followed from the preoperative period through postoperative month 6. Clinical and functional assessments will be performed at baseline, postoperative week 6, month 3, and month 6. Nerve conduction findings will be evaluated at baseline and postoperative month 6. No experimental drug, device, surgical technique, or additional treatment will be assigned by the study.
- Masking
- None (open label)
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istanbul Medipol University Hospital
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, salih tan, Istanbul Medipol University Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07803939
- Sponsor's protocol ID
- IMU-CTS-2026-01
- Acronym
- ELECTRO-CTS
- Status last verified
- Sep 2026
- First submitted
- 1 Sep 2026
- Last updated
- 4 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship Between Electrophysiological Recovery of the Median Nerve and Clinical and Functional Outcomes After Carpal Tunnel Release: A Prospective Observational Cohort Study
- ClinicalTrials.gov ID
- NCT07803939
- Acronym / sponsor ID
- ELECTRO-CTS / IMU-CTS-2026-01
- Conditions
- Carpal Tunnel Syndrome (CTS)
- Keywords
- Carpal Tunnel Release, Median Nerve, Electrophysiological Recovery, Hand Function, QuickDASH
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Istanbul Medipol University HospitalUniversity, hospital or other
- Study start
- Sep 2026 (estimated)
- Primary completion
- Oct 2026 (estimated)
- Study completion
- Nov 2026 (estimated)
- First posted
- 4 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Carpal tunnel syndrome occurs when the median nerve is compressed at the wrist. It can cause pain, numbness, tingling, reduced hand strength, and difficulty performing daily activities. Carpal tunnel release surgery is commonly performed when symptoms do not improve with conservative treatment or when nerve compression is severe. However, recovery after surgery may differ between patients, and improvement in nerve conduction may not occur at the same rate as improvement in symptoms and hand function.
The purpose of this prospective observational study is to examine the relationship between electrophysiological recovery of the median nerve and clinical and functional recovery after carpal tunnel release surgery. Adults who are already scheduled to undergo primary carpal tunnel release as part of their routine clinical care will be invited to participate. The decision to perform surgery will be made by the treating physician independently of study participation.
Participants will undergo clinical and functional assessments before surgery and at postoperative week 8 These assessments will include questionnaires about carpal tunnel symptoms and upper-extremity function, pain severity, grip and pinch strength, sensory testing, and clinical examination. Nerve conduction studies will be evaluated before surgery and at postoperative month 3.
The study will assess whether changes in median nerve conduction are associated with changes in symptoms, upper-extremity function, pain, hand strength, and sensory function. The possible effects of age, sex, body mass index, symptom duration, diabetes, and preoperative electrophysiological severity on recovery will also be examined. No experimental drug, device, surgical technique, or additional treatment will be assigned as part of this study.
Detailed description
Carpal tunnel syndrome is the most common peripheral nerve entrapment neuropathy of the upper extremity and results from compression of the median nerve within the carpal tunnel. Patients may experience numbness, tingling, nocturnal paresthesia, pain, sensory loss, reduced grip strength, and, in advanced cases, thenar muscle weakness or atrophy. These impairments may negatively affect sleep, occupational performance, daily activities, and overall upper-extremity function.
Carpal tunnel release surgery aims to decompress the median nerve and is generally performed in patients who do not obtain adequate benefit from conservative treatment or who have progressive neurological or electrophysiological abnormalities. Although improvements in pain, paresthesia, and hand function are commonly observed after surgery, the rate and extent of recovery may vary between patients. Clinical improvement may also occur at a different rate from electrophysiological recovery of the median nerve.
This is a single-center, prospective observational cohort study involving adults with clinically and electrophysiologically confirmed carpal tunnel syndrome who are scheduled to undergo primary carpal tunnel release surgery as part of routine clinical care. The decision to perform surgery and the selection of the surgical technique will be made by the treating physician independently of participation in the study. Participation will not influence the surgical decision or the participant's routine treatment. No experimental intervention or additional treatment will be assigned by the investigators.
Only the surgically treated hand will be included in the analysis. For participants with bilateral carpal tunnel syndrome who undergo unilateral surgery during the study period, the operated hand will be evaluated. Two hands from the same participant will not be analyzed as independent observations.
Clinical and functional evaluations will be performed at baseline before surgery and at postoperative week 8. The evaluations will include the Boston Carpal Tunnel Questionnaire, Quick Disabilities of the Arm, Shoulder and Hand questionnaire, Numeric Rating Scale for pain, grip strength, pinch strength, Semmes-Weinstein monofilament testing, static two-point discrimination, and Tinel and Phalen tests.
Standard nerve conduction study findings obtained during routine clinical evaluation will be recorded at baseline and postoperative month 3. Electrophysiological variables will include median nerve distal motor latency, compound muscle action potential amplitude, sensory distal latency, sensory nerve action potential amplitude, and sensory nerve conduction velocity. Electrophysiological severity will be classified using the Bland neurophysiological grading scale. Needle electromyography will not be mandatory for study participation and will only be performed when clinically indicated as part of routine care.
The primary objective is to determine whether electrophysiological changes in the median nerve between baseline and postoperative month 6 are associated with changes in carpal tunnel symptoms and upper-extremity function. Particular emphasis will be placed on changes in distal motor latency and sensory nerve conduction velocity and their relationships with changes in the Boston Carpal Tunnel Questionnaire and QuickDASH scores.
Secondary analyses will examine the relationships between electrophysiological recovery and changes in pain severity, grip strength, pinch strength, monofilament sensation, and two-point discrimination. The study will also investigate whether demographic and clinical factors, including age, sex, body mass index, symptom duration, hand dominance, operated side, occupational hand use, diabetes mellitus, and preoperative electrophysiological severity, are associated with postoperative clinical, functional, or electrophysiological recovery.
The planned enrollment is approximately 70 to 100 participants. Findings from this study may help clarify the extent to which objective nerve conduction recovery reflects patient-reported and performance-based recovery after carpal tunnel release surgery.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- This is a prospective, single-group study of adults undergoing primary carpal tunnel release surgery. All participants will receive carpal tunnel release as part of their routine clinical care and will be followed from the preoperative period through postoperative month 6. Clinical and functional assessments will be performed at baseline, postoperative week 6, month 3, and month 6. Nerve conduction findings will be evaluated at baseline and postoperative month 6. No experimental drug, device, surgical technique, or additional treatment will be assigned by the study.
| Arm | Type | Receives |
|---|---|---|
| Carpal Tunnel Release Group | Other | Procedure: Primary Carpal Tunnel Release SurgeryParticipants with clinically and electrophysiologically confirmed carpal tunnel syndrome who are scheduled to undergo primary carpal tunnel release surgery as part of routine clinical care will be included in this single study arm. The decision to perform surgery and the surgical technique will be determined by the treating physician independently of study participation. Clinical and functional assessments will be performed before surgery and at postoperative week 8. Median nerve conduction findings will be evaluated before surgery and at postoperative month 3. No experimental drug, device, surgical technique, or additional treatment will be administered as part of the study. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (9 listed)
- Age between 18 and 75 years.
- Clinical and electrophysiological diagnosis of carpal tunnel syndrome.
- Scheduled to undergo primary carpal tunnel release surgery based on routine clinical evaluation.
- Availability of a preoperative nerve conduction study.
- Ability to understand and complete the study assessments and questionnaires.
Key exclusion criteria (13 listed)
- Previous carpal tunnel release surgery on the study hand.
- Planned revision carpal tunnel surgery.
- Electrophysiological evidence of generalized polyneuropathy.
- Another peripheral neuropathy affecting the median nerve or function of the study hand.
- Active cervical radiculopathy or brachial plexopathy.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Primary Carpal Tunnel Release SurgeryParticipants will undergo primary carpal tunnel release surgery as part of their routine clinical care. The procedure aims to decompress the median nerve by releasing the transverse carpal ligament. The decision to perform surgery, the timing of surgery, and the surgical technique will be determined by the treating physician independently of study participation. The study will not require an experimental surgical technique or any modification of the participant's standard treatment. Participants will undergo clinical and functional follow-up assessments, and median nerve conduction findings will be evaluated before surgery and at postoperative month 6. | Procedure or surgery | Carpal Tunnel Release Group |
Primary outcome
Change in Median Nerve Distal Motor Latency
Time frame: Baseline and postoperative week 8
Median nerve distal motor latency will be measured by a standardized nerve conduction study and recorded in milliseconds (ms). Change will be calculated as the postoperative month 6 value minus the preoperative value. A reduction in distal motor latency indicates electrophysiological improvement.
8 secondary outcomes
Change in Median Nerve Sensory Nerve Conduction Velocity
Time frame: Baseline and postoperative week 8
The Boston Carpal Tunnel Questionnaire consists of the Symptom Severity Scale and the Functional Status Scale. Each item is scored from 1 to 5, and the mean score is calculated separately for each subscale. Higher scores indicate greater symptom severity
Time frame: Baseline, postoperative week 8
Change in Quick Disabilities of the Arm, Shoulder and Hand Score
Time frame: Baseline, postoperative week 8
Change in Median Nerve Sensory Nerve Action Potential Amplitude
Time frame: Time Frame: Baseline and postoperative month 3
Change in Median Nerve Compound Muscle Action Potential Amplitude
Time frame: Time Frame: Baseline and postoperative month 3
Change in Numeric Rating Scale Pain Score
Time frame: Baseline, postoperative week 8, month 3,
Change in Semmes-Weinstein Monofilament Sensory Threshold
Time frame: Baseline, postoperative week 8, month 3,
Change in Static Two-Point Discrimination Distance
Time frame: Time Frame: Baseline, postoperative week 8, month 3,
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing Primary Carpal Tunnel Release Surgery in people with Carpal Tunnel Syndrome (CTS), run by Istanbul Medipol University Hospital.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 13 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 4 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Median Nerve Distal Motor Latency (time frame: Baseline and postoperative week 8). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2026.