DENT IMPLANTSPhase 2NCT07800949
Clinical and Radiographic Evaluation of Using Regular Versus Narrow Diameter Dental Implantto Support Mandibular Complete Over Denture
A Phase 2 study testing Implant in people with DENT IMPLANTS, run by Mostafa Bahaa at 1 site in Egypt.
Trial summary
After teeth extraction and over years of removable denture wearing, atrophy of residual alveolar ridges progresses. The lower complete denture is the most problem issue in oral cavity due to bone loss and presence of the tongue, which is the most movable part in the oral cavity, this condition resulting in a lack of… Read more about this study
- Who is it for?
- Ages 55 to 65 years
- Conditions the study is for
- DENT IMPLANTS
- What is being tested?
- Implant
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 12 participants
- Where
- 1 siteEgypt
- Study dates
- 25 Aug 2026to 30 Oct 2027
- Phase
- Phase 2
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 55 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- . All patients should be free from any systemic diseases that might affect the bone quality or post-operative healing.
- Completely edentulous patients with their age range from 55 to 65 years
- All patients have Angle's Class I maxillomandibular relationship
- Normal facial symmetry with no signs and symptoms of temporomandibular disorders.
- Cooperative patients
- Adequate inter-arch space.
Show all 11Show fewer
- All patients have recent and old extractions ,a period of at least 6 months from the date of last extraction.
- All patients have lower arch with irregular buccolingual thickness .
- Edentulous ridge covered by healthy firm mucoperiosteum, without abnormal morphology.
- Normal tongue size.
- All the selected patients should be free from any oral pathological lesions such as cysts, remaining root, or residual infection.
Who cannot join
- General health conditions preclude a minor surgical intervention, risk patients are excluded.
- Local anesthesia with a vasoconstrictor is contraindicated
- Immunosuppressive therapy, prolonged intake of antibiotics or corticosteroids, or brittle metabolic disease history.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Al-Azhar University
Cairo
Basma Mahrous, PhD, 01067009096, manal.hamouda@phrm.menoufia.edu.eg
About this study
After teeth extraction and over years of removable denture wearing, atrophy of residual alveolar ridges progresses. The lower complete denture is the most problem issue in oral cavity due to bone loss and presence of the tongue, which is the most movable part in the oral cavity, this condition resulting in a lack of retention, stability, and support of the dentures, which directly affect the patient's confidence, function, comfort and bring a major challenge for prosthodontics
- Conditions
- DENT IMPLANTS
- Being tested
- Implant
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ImplantOther
Two (regular and narrow) dental implants will be placed in the canine region of the edentulous mandible according to surgical protocols, its 7 accurate position will be determined as relates to the vital structures by the cone beam radiograph.
| Study group | Role | What they receive |
|---|---|---|
| Treatment arm | Other | 12 edentulous patients have mandibular ridges and have Angle's Class I maxillomandibular relationship Receives: Other: Implant |
What is being measured
The primary outcome is the main question the study is designed to answer.
Radiographical evaluation
measuring the crestal bone height around implant by cone beam computed tomography (CBCT).
Measured: 3 months
Radiographically
measuring the crestal bone density around implant by cone beam computed tomography (CBCT).
Measured: 3 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Sep 2026
- Study start25 Aug 2026
- Primary completion25 Aug 2027 (estimated)
- Study completion30 Oct 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for DENT IMPLANTSStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase 2
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 12 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mostafa Bahaa
- Sponsor type
- University, hospital or other
- Collaborators
- Faculty of Dental Medicine for Girls
- Responsible party
- Sponsor-investigator, Mostafa Bahaa, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07800949
- Sponsor's protocol ID
- 54789
- Status last verified
- Sep 2026
- First submitted
- 16 Aug 2026
- Last updated
- 2 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinical and Radiographic Evaluation of Using Regular Versus Narrow Diameter Dental Implantto Support Mandibular Complete Over Denture
- ClinicalTrials.gov ID
- NCT07800949
- Acronym / sponsor ID
- 54789
- Conditions
- DENT IMPLANTS
- Phase
- Phase 2
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 12 participants (estimated)
- Lead sponsor
- Mostafa BahaaUniversity, hospital or other
- Collaborators
- Faculty of Dental Medicine for Girls
- Study start
- 25 Aug 2026 (actual)
- Primary completion
- 25 Aug 2027 (estimated)
- Study completion
- 30 Oct 2027 (estimated)
- First posted
- 2 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
After teeth extraction and over years of removable denture wearing, atrophy of residual alveolar ridges progresses. The lower complete denture is the most problem issue in oral cavity due to bone loss and presence of the tongue, which is the most movable part in the oral cavity, this condition resulting in a lack of retention, stability, and support of the dentures, which directly affect the patient's confidence, function, comfort and bring a major challenge for prosthodontics
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Treatment arm | Other | Other: Implant12 edentulous patients have mandibular ridges and have Angle's Class I maxillomandibular relationship |
Who may qualify
- Ages
- 55 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (11 listed)
- . All patients should be free from any systemic diseases that might affect the bone quality or post-operative healing.
- Completely edentulous patients with their age range from 55 to 65 years
- All patients have Angle's Class I maxillomandibular relationship
- Normal facial symmetry with no signs and symptoms of temporomandibular disorders.
- Cooperative patients
Key exclusion criteria (3 listed)
- General health conditions preclude a minor surgical intervention, risk patients are excluded.
- Local anesthesia with a vasoconstrictor is contraindicated
- Immunosuppressive therapy, prolonged intake of antibiotics or corticosteroids, or brittle metabolic disease history.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ImplantTwo (regular and narrow) dental implants will be placed in the canine region of the edentulous mandible according to surgical protocols, its 7 accurate position will be determined as relates to the vital structures by the cone beam radiograph. | Other | Treatment arm |
Primary outcome
Radiographical evaluation
Time frame: 3 months
measuring the crestal bone height around implant by cone beam computed tomography (CBCT).
Radiographically
Time frame: 3 months
measuring the crestal bone density around implant by cone beam computed tomography (CBCT).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A Phase 2 study testing Implant in people with DENT IMPLANTS, run by Mostafa Bahaa at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 11 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
What does this phase mean?
Phase 2 studies give the treatment to a larger group to see whether it has the intended effect and to keep checking safety.
Not every study follows the same path, and some studies (observational studies, device studies) have no phase.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Radiographical evaluation (time frame: 3 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.